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The map label for this gene is accB

Identifier: 17232549

GI number: 17232549

Start: 6030127

End: 6030675

Strand: Reverse

Name: accB

Synonym: all5057

Alternate gene names: 17232549

Gene position: 6030675-6030127 (Counterclockwise)

Preceding gene: 17232550

Following gene: 17232548

Centisome position: 94.03

GC content: 47.36

Gene sequence:

>549_bases
GTGCCATTGGACTTTAATGAAATCCGTCAACTGCTGACAACTATTGCACAAACAGATATCGCGGAAGTAACGCTCAAAAG
TGATGATTTTGAACTAACGGTGCGTAAAGCTGTTGGTGTGAATAATAGTGTTGTGCCGGTTGTGACAGCACCCTTGAGTG
GTGTGGTAGGTTCGGGATTGCCATCGGCTATACCGATTGTAGCCCATGCTGCCCCATCTCCATCTCCAGAGCCGGGAACA
AGCCGTGCTGCTGATCATGCTGTCACGAGTTCTGGCTCACAGCCAGGAGCAAAAATCATTGACCAAAAATTAGCAGAAGT
GGCTTCCCCAATGGTGGGAACATTTTACCGCGCTCCTGCACCAGGTGAAGCGGTATTTGTGGAAGTCGGCGATCGCATCC
GTCAAGGTCAAACCGTCTGCATCATCGAAGCAATGAAGCTGATGAATGAAATTGAGGCTGATGTTTCTGGGCAAGTGATC
GAAATTCTCGTCCAAAACGGCGAACCTGTAGAATATAATCAACCTTTGATGAGAATTAAACCAGATTAA

Upstream 100 bases:

>100_bases
CTGGATTCCCTTAAGGTTTCTGAGTCTCAATGGTAGATGGATTTTGGAGAGTTGGTATGAAAAATTCTTTATTTACGGAC
TGGTCGAGGTAATAAAAACT

Downstream 100 bases:

>100_bases
GTATTAATGTATATAGGTGAGTCATTACTAACTCAAGTTGCTAGTTATGTTTGGTAATTGGTAACTGGTGATTGCTAATT
GGTAATTGAGAAAAATTTTA

Product: biotin carboxyl carrier protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MPLDFNEIRQLLTTIAQTDIAEVTLKSDDFELTVRKAVGVNNSVVPVVTAPLSGVVGSGLPSAIPIVAHAAPSPSPEPGT
SRAADHAVTSSGSQPGAKIIDQKLAEVASPMVGTFYRAPAPGEAVFVEVGDRIRQGQTVCIIEAMKLMNEIEADVSGQVI
EILVQNGEPVEYNQPLMRIKPD

Sequences:

>Translated_182_residues
MPLDFNEIRQLLTTIAQTDIAEVTLKSDDFELTVRKAVGVNNSVVPVVTAPLSGVVGSGLPSAIPIVAHAAPSPSPEPGT
SRAADHAVTSSGSQPGAKIIDQKLAEVASPMVGTFYRAPAPGEAVFVEVGDRIRQGQTVCIIEAMKLMNEIEADVSGQVI
EILVQNGEPVEYNQPLMRIKPD
>Mature_181_residues
PLDFNEIRQLLTTIAQTDIAEVTLKSDDFELTVRKAVGVNNSVVPVVTAPLSGVVGSGLPSAIPIVAHAAPSPSPEPGTS
RAADHAVTSSGSQPGAKIIDQKLAEVASPMVGTFYRAPAPGEAVFVEVGDRIRQGQTVCIIEAMKLMNEIEADVSGQVIE
ILVQNGEPVEYNQPLMRIKPD

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain

Homologues:

Organism=Escherichia coli, GI1789653, Length=178, Percent_Identity=37.6404494382022, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BCCP_NOSS1 (Q06881)

Other databases:

- EMBL:   L14863
- EMBL:   BA000019
- PIR:   AI2437
- PIR:   B53311
- RefSeq:   NP_489097.1
- ProteinModelPortal:   Q06881
- SMR:   Q06881
- STRING:   Q06881
- GeneID:   1108661
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all5057
- NMPDR:   fig|103690.1.peg.5364
- eggNOG:   COG0511
- HOGENOM:   HBG745267
- OMA:   EPRVEMV
- ProtClustDB:   CLSK286668
- BioCyc:   NSP103690:ALL5057-MONOMER
- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053
- PRINTS:   PR01071
- TIGRFAMs:   TIGR00531

Pfam domain/function: PF00364 Biotin_lipoyl; SSF51230 Hybrid_motif

EC number: NA

Molecular weight: Translated: 19180; Mature: 19049

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00188 BIOTIN; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDFNEIRQLLTTIAQTDIAEVTLKSDDFELTVRKAVGVNNSVVPVVTAPLSGVVGSGL
CCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCEEEEEECCHHHHHCCCC
PSAIPIVAHAAPSPSPEPGTSRAADHAVTSSGSQPGAKIIDQKLAEVASPMVGTFYRAPA
CCHHCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCC
PGEAVFVEVGDRIRQGQTVCIIEAMKLMNEIEADVSGQVIEILVQNGEPVEYNQPLMRIK
CCCEEEEECCHHHHCCCEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEC
PD
CC
>Mature Secondary Structure 
PLDFNEIRQLLTTIAQTDIAEVTLKSDDFELTVRKAVGVNNSVVPVVTAPLSGVVGSGL
CCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCEEEEEECCHHHHHCCCC
PSAIPIVAHAAPSPSPEPGTSRAADHAVTSSGSQPGAKIIDQKLAEVASPMVGTFYRAPA
CCHHCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCC
PGEAVFVEVGDRIRQGQTVCIIEAMKLMNEIEADVSGQVIEILVQNGEPVEYNQPLMRIK
CCCEEEEECCHHHHCCCEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEC
PD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102363; 11759840