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The map label for this gene is cvrA [H]

Identifier: 17232324

GI number: 17232324

Start: 5751639

End: 5752928

Strand: Reverse

Name: cvrA [H]

Synonym: all4832

Alternate gene names: 17232324

Gene position: 5752928-5751639 (Counterclockwise)

Preceding gene: 17232326

Following gene: 17232322

Centisome position: 89.7

GC content: 37.91

Gene sequence:

>1290_bases
ATGGTAGATATTTATATTATTGACCTATTTGTAATTGGGCTACTTTTGCTCGTCGTTACATTAGGTTCTGGTTGGATTTC
GCGGTTACCTCTATCTTTTGCCTTGATATATCTCTTAGTGGGAATCATTCTCGGCCCTTATGGCTTTGGGTTGATACAAC
TAAGGCGGGATGATGTATTTAATGCAGATTTATTGGAAAGAATCACAGAATTTGTCGTCATTATTTCCGTTTTTAGCTGT
GGATTAAAAATAATCCATCCCCTGAGACGTAGAGTGTGGGATATTACCGCACGCCTTATTGGTTTCTTAATGCCTATTTC
TATTTTTGCCATAGCTGTTGTAGCTAAATTATTTTTAGGCATGAATTGGGGCGAAGCGATTTTATTAGGAGCCATTCTTG
CCCCCACTGACCCAGTGTTAGCATCGGAAGTTCAACTAACAGATATCAATGATAAAGATGAGCTACGTTTTGGTTTAACC
TCGGAAGGTGGTTTAAATGATGCCTTAGCATTTCCTTTTGTCTATTTTGGACTTTTTGCTATCAAAGATGACAACTGGAA
CACATGGTTTAAGCAGTGGGTAGCAGTTGATTTAATTTGGGCGATCGCTGCTGCATTAATTATGGGTTTTGTTGTTGCCA
AAGCAATAGTTTGGATTGATCAAAAAGTCCAGAAGCGTCGTTCTGCTGATGCGTTGATGGAAGATTTTATTGCTCTCAGT
GCAATATTGTTAACTTATTCTCTAACAGAAGTTGTCAACGGTTATGGATTTTTAGCAGTATTTATTGCTGGATTAGTTTT
CCAAGATACTTATAGAAATCCAGAAAAACCACTTGCACAATTAGAATTTATTGAACGCTTAGAAAAACTTTTAGAAGTTG
GCACAATATTATTATTAGGTTCGATATTACTATGGCAACCAATAATTAACTATGGCTATCAGTCTTTGATAATAATTATT
TTCCTATTTTTAATTATTCGACCTATTGGAGCCTGGATTAGCACCATTGGCAAACGTCCTTTAGCATCCCATCGCCGCCG
CCTCCATCCTGGAACTCGCTGGTTACTTGGCTGGTTTGGCATTCGTGGCGTTGGTTCCTTATATTATCTCGCCTATGCCT
TTGGTCATGGTTTAAAAGATGCAGTTGCCGAAGAAATAGCTTGGATAACTTACACTACGGTGGTAGTTTCTGTAGTTATA
CATGGCATATCTGCTACGCCATTAATGAGTTGGTATGAACGCAATATTGCTAATGAGCAGAAAACTTCTTTGCCTGAAAC
TTTAAATTAA

Upstream 100 bases:

>100_bases
GATAAATCATCTTAATAATATCTATCTGTAGATCATTTATACAAATAGGCGATCGCTTCTAAAATAACGTAGCTATCCAG
ATTTTTTATACATAAATTAT

Downstream 100 bases:

>100_bases
ATATGTTATCGTTTTTGACCAAACTAGTATGAGTGGTCAAAGAGAAATCAAAACCATTCATTTTCATTTCTCTATCTCAT
CGTTTTTGACCAAACTAGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MVDIYIIDLFVIGLLLLVVTLGSGWISRLPLSFALIYLLVGIILGPYGFGLIQLRRDDVFNADLLERITEFVVIISVFSC
GLKIIHPLRRRVWDITARLIGFLMPISIFAIAVVAKLFLGMNWGEAILLGAILAPTDPVLASEVQLTDINDKDELRFGLT
SEGGLNDALAFPFVYFGLFAIKDDNWNTWFKQWVAVDLIWAIAAALIMGFVVAKAIVWIDQKVQKRRSADALMEDFIALS
AILLTYSLTEVVNGYGFLAVFIAGLVFQDTYRNPEKPLAQLEFIERLEKLLEVGTILLLGSILLWQPIINYGYQSLIIII
FLFLIIRPIGAWISTIGKRPLASHRRRLHPGTRWLLGWFGIRGVGSLYYLAYAFGHGLKDAVAEEIAWITYTTVVVSVVI
HGISATPLMSWYERNIANEQKTSLPETLN

Sequences:

>Translated_429_residues
MVDIYIIDLFVIGLLLLVVTLGSGWISRLPLSFALIYLLVGIILGPYGFGLIQLRRDDVFNADLLERITEFVVIISVFSC
GLKIIHPLRRRVWDITARLIGFLMPISIFAIAVVAKLFLGMNWGEAILLGAILAPTDPVLASEVQLTDINDKDELRFGLT
SEGGLNDALAFPFVYFGLFAIKDDNWNTWFKQWVAVDLIWAIAAALIMGFVVAKAIVWIDQKVQKRRSADALMEDFIALS
AILLTYSLTEVVNGYGFLAVFIAGLVFQDTYRNPEKPLAQLEFIERLEKLLEVGTILLLGSILLWQPIINYGYQSLIIII
FLFLIIRPIGAWISTIGKRPLASHRRRLHPGTRWLLGWFGIRGVGSLYYLAYAFGHGLKDAVAEEIAWITYTTVVVSVVI
HGISATPLMSWYERNIANEQKTSLPETLN
>Mature_429_residues
MVDIYIIDLFVIGLLLLVVTLGSGWISRLPLSFALIYLLVGIILGPYGFGLIQLRRDDVFNADLLERITEFVVIISVFSC
GLKIIHPLRRRVWDITARLIGFLMPISIFAIAVVAKLFLGMNWGEAILLGAILAPTDPVLASEVQLTDINDKDELRFGLT
SEGGLNDALAFPFVYFGLFAIKDDNWNTWFKQWVAVDLIWAIAAALIMGFVVAKAIVWIDQKVQKRRSADALMEDFIALS
AILLTYSLTEVVNGYGFLAVFIAGLVFQDTYRNPEKPLAQLEFIERLEKLLEVGTILLLGSILLWQPIINYGYQSLIIII
FLFLIIRPIGAWISTIGKRPLASHRRRLHPGTRWLLGWFGIRGVGSLYYLAYAFGHGLKDAVAEEIAWITYTTVVVSVVI
HGISATPLMSWYERNIANEQKTSLPETLN

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 48119; Mature: 48119

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDIYIIDLFVIGLLLLVVTLGSGWISRLPLSFALIYLLVGIILGPYGFGLIQLRRDDVF
CEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
NADLLERITEFVVIISVFSCGLKIIHPLRRRVWDITARLIGFLMPISIFAIAVVAKLFLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MNWGEAILLGAILAPTDPVLASEVQLTDINDKDELRFGLTSEGGLNDALAFPFVYFGLFA
CCCCHHHHHHHHHCCCCCHHHCCEEEECCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHH
IKDDNWNTWFKQWVAVDLIWAIAAALIMGFVVAKAIVWIDQKVQKRRSADALMEDFIALS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILLTYSLTEVVNGYGFLAVFIAGLVFQDTYRNPEKPLAQLEFIERLEKLLEVGTILLLG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SILLWQPIINYGYQSLIIIIFLFLIIRPIGAWISTIGKRPLASHRRRLHPGTRWLLGWFG
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHH
IRGVGSLYYLAYAFGHGLKDAVAEEIAWITYTTVVVSVVIHGISATPLMSWYERNIANEQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCH
KTSLPETLN
HHCCCCCCC
>Mature Secondary Structure
MVDIYIIDLFVIGLLLLVVTLGSGWISRLPLSFALIYLLVGIILGPYGFGLIQLRRDDVF
CEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
NADLLERITEFVVIISVFSCGLKIIHPLRRRVWDITARLIGFLMPISIFAIAVVAKLFLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MNWGEAILLGAILAPTDPVLASEVQLTDINDKDELRFGLTSEGGLNDALAFPFVYFGLFA
CCCCHHHHHHHHHCCCCCHHHCCEEEECCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHH
IKDDNWNTWFKQWVAVDLIWAIAAALIMGFVVAKAIVWIDQKVQKRRSADALMEDFIALS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILLTYSLTEVVNGYGFLAVFIAGLVFQDTYRNPEKPLAQLEFIERLEKLLEVGTILLLG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SILLWQPIINYGYQSLIIIIFLFLIIRPIGAWISTIGKRPLASHRRRLHPGTRWLLGWFG
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHH
IRGVGSLYYLAYAFGHGLKDAVAEEIAWITYTTVVVSVVIHGISATPLMSWYERNIANEQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCH
KTSLPETLN
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]