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The map label for this gene is mdlB [C]

Identifier: 17232223

GI number: 17232223

Start: 5638395

End: 5639063

Strand: Reverse

Name: mdlB [C]

Synonym: all4731

Alternate gene names: 17232223

Gene position: 5639063-5638395 (Counterclockwise)

Preceding gene: 17232224

Following gene: 17232222

Centisome position: 87.92

GC content: 43.65

Gene sequence:

>669_bases
ATGAGAACTCCAGCCCCAGTTATTGCCTCCGAGCAACAAGCAACTAAGCAACTTTCAACCTTACGACGCTTCTTACAATA
CCTGCGTCCCTTTCGCAAAGAAGTTCCCATTGCTTTGAGTTTAGTATTAACTGGCGCTGCCACCCAGGCGATCGGGCCGT
TTTTACTGGGTTGGTCAGTTGATAACCTGATAGCCAAAGGGAATTTACAAGGATTACTACTGTTATTAGTATTATTAGGG
CTAAATTATAGTTTTGGTATCTGGGCAATCCGTGGGCAAGTTATTCGCGTCGGCTGGATTATGCAGCGATTACTGGCTCA
GTTGAGGCAAGACATTTTTACTAAAATTCAGAGTTTACCACTCAGCTTTTTTGACCGTAGTGAAGCCGGCGATTTAATGA
GTCGTCTGCTAAATGATGTCAACACTGTTAATCAAGCCTTTGGGCAAACAGTGGCACAAATGCTAGGTAATACCTTCAGT
TTGGTGGGTATTGTCATTGCTATGCTCTCTATTAATTTACAACTTGGTTTGTTAAGTAACCTAGTCGTCCCTCTGATGAT
TTTTACCACCAGCTTATTTGCCCGGTGGGCTAGGACTAAATTTCGCGTCACCAGACAAACCATCGGAGAACTTTCCGCCA
AGTTAGAAGAAGACATTGGCAGTGTGTGA

Upstream 100 bases:

>100_bases
GAGGAGCGGGGGAGCAGGGGAGCAGGGGAGACATAAGAAGTAATGATTGTTTACTCCTAACTCATTACCCATTACCCATT
ACCCATTACCCATTACCCCC

Downstream 100 bases:

>100_bases
GAAGCCCAAGCCTTTAATCGGGTACATCTCAACATCGCAGAATTCGACATTCTCAACGCCGCTAATCGTGATGCCAACGT
TGAGGCTGTGGCGATTACGG

Product: ATP-binding protein of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRTPAPVIASEQQATKQLSTLRRFLQYLRPFRKEVPIALSLVLTGAATQAIGPFLLGWSVDNLIAKGNLQGLLLLLVLLG
LNYSFGIWAIRGQVIRVGWIMQRLLAQLRQDIFTKIQSLPLSFFDRSEAGDLMSRLLNDVNTVNQAFGQTVAQMLGNTFS
LVGIVIAMLSINLQLGLLSNLVVPLMIFTTSLFARWARTKFRVTRQTIGELSAKLEEDIGSV

Sequences:

>Translated_222_residues
MRTPAPVIASEQQATKQLSTLRRFLQYLRPFRKEVPIALSLVLTGAATQAIGPFLLGWSVDNLIAKGNLQGLLLLLVLLG
LNYSFGIWAIRGQVIRVGWIMQRLLAQLRQDIFTKIQSLPLSFFDRSEAGDLMSRLLNDVNTVNQAFGQTVAQMLGNTFS
LVGIVIAMLSINLQLGLLSNLVVPLMIFTTSLFARWARTKFRVTRQTIGELSAKLEEDIGSV
>Mature_222_residues
MRTPAPVIASEQQATKQLSTLRRFLQYLRPFRKEVPIALSLVLTGAATQAIGPFLLGWSVDNLIAKGNLQGLLLLLVLLG
LNYSFGIWAIRGQVIRVGWIMQRLLAQLRQDIFTKIQSLPLSFFDRSEAGDLMSRLLNDVNTVNQAFGQTVAQMLGNTFS
LVGIVIAMLSINLQLGLLSNLVVPLMIFTTSLFARWARTKFRVTRQTIGELSAKLEEDIGSV

Specific function: Unknown

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955966, Length=207, Percent_Identity=25.1207729468599, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI45243524, Length=207, Percent_Identity=25.1207729468599, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI9955968, Length=207, Percent_Identity=25.1207729468599, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1786654, Length=210, Percent_Identity=27.1428571428571, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 24630; Mature: 24630

Theoretical pI: Translated: 11.44; Mature: 11.44

Prosite motif: PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPAPVIASEQQATKQLSTLRRFLQYLRPFRKEVPIALSLVLTGAATQAIGPFLLGWSV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
DNLIAKGNLQGLLLLLVLLGLNYSFGIWAIRGQVIRVGWIMQRLLAQLRQDIFTKIQSLP
HHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSFFDRSEAGDLMSRLLNDVNTVNQAFGQTVAQMLGNTFSLVGIVIAMLSINLQLGLLSN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LVVPLMIFTTSLFARWARTKFRVTRQTIGELSAKLEEDIGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTPAPVIASEQQATKQLSTLRRFLQYLRPFRKEVPIALSLVLTGAATQAIGPFLLGWSV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
DNLIAKGNLQGLLLLLVLLGLNYSFGIWAIRGQVIRVGWIMQRLLAQLRQDIFTKIQSLP
HHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSFFDRSEAGDLMSRLLNDVNTVNQAFGQTVAQMLGNTFSLVGIVIAMLSINLQLGLLSN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LVVPLMIFTTSLFARWARTKFRVTRQTIGELSAKLEEDIGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]