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The map label for this gene is infC [H]

Identifier: 17232115

GI number: 17232115

Start: 5528319

End: 5528933

Strand: Reverse

Name: infC [H]

Synonym: all4623

Alternate gene names: 17232115

Gene position: 5528933-5528319 (Counterclockwise)

Preceding gene: 17232116

Following gene: 17232114

Centisome position: 86.2

GC content: 45.53

Gene sequence:

>615_bases
GTGCTGCTTAGGCAGACCAATCAAAACAAAGCAATCAAGTCCACATTACATCACTTAACAAAGAAGCTCCCACAAATCAT
AATGCCTGTGATTGAGAAAAAAAGAACTCGCGATCTGCCCCAAATTAACGAACGGATCCGCTTCCCGAAAATTCGAGTCA
TTGACACTGATGGTTCCCAGCTAGGAATTCTAACTCCACAGGAAGCGCTGCAACTAGCAGAGGAGAAGGAGTTGGATTTA
GTACTGCTCAGTGACAAGGCCGACCCGCCGGTGTGTCGGATTATGGATTACGGGAAATACAAGTTCGAGCAGGAGAAGAA
GGCGCGGGAAGCTCGGAAGAAACAGCACACGGCTGATGTGAAAGAAGTGAAGATGCGCTACAAAATTGAGGAACACGACT
ACAATGTGCGTGTTAAGCAAGCAGAACGCTTCTTAAAAGATGGTGATAAAGTCAAAGCAACTGTGATGTTCCGGGGTCGA
GAGATTCAACACAGTGATTTAGCTGAAGATTTATTGAAGCGAATGGCAACGGATCTGGAACCGTTTGGTGAAGTGCAACA
AGCACCCAAAAAAGAAGGGCGAAATATGATGATGCTTATCTCGCCTAAGAAGTAA

Upstream 100 bases:

>100_bases
GTGAGTAAAATAACAAATACAGAAACCAAATAAACTATTTTATGGATTAGTTCCTATAAAACTATAGACTCCTTCTTAAA
TTCTCAGTTATTTTAGTATT

Downstream 100 bases:

>100_bases
TACTCATAAGTATTCTTGTAACCAAGTAATCCACCACTGAAAATATCAAAACGGCTTCACCGTCGTTGAAATTAATTGCA
ACTTGATAGTCCTGAACTCT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLLRQTNQNKAIKSTLHHLTKKLPQIIMPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDL
VLLSDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGR
EIQHSDLAEDLLKRMATDLEPFGEVQQAPKKEGRNMMMLISPKK

Sequences:

>Translated_204_residues
MLLRQTNQNKAIKSTLHHLTKKLPQIIMPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDL
VLLSDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGR
EIQHSDLAEDLLKRMATDLEPFGEVQQAPKKEGRNMMMLISPKK
>Mature_204_residues
MLLRQTNQNKAIKSTLHHLTKKLPQIIMPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDL
VLLSDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGR
EIQHSDLAEDLLKRMATDLEPFGEVQQAPKKEGRNMMMLISPKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=165, Percent_Identity=46.0606060606061, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 23901; Mature: 23901

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRQTNQNKAIKSTLHHLTKKLPQIIMPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCE
LGILTPQEALQLAEEKELDLVLLSDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADV
EECCCHHHHHHHHHHCCCCEEEECCCCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHCCH
KEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLE
HHHHHHHEEECCCCCEEHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCC
PFGEVQQAPKKEGRNMMMLISPKK
HHHHHHHCHHHCCCCEEEEEECCC
>Mature Secondary Structure
MLLRQTNQNKAIKSTLHHLTKKLPQIIMPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCE
LGILTPQEALQLAEEKELDLVLLSDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADV
EECCCHHHHHHHHHHCCCCEEEECCCCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHCCH
KEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLE
HHHHHHHEEECCCCCEEHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCC
PFGEVQQAPKKEGRNMMMLISPKK
HHHHHHHCHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA