Click here to switch to the map view.

The map label for this gene is yjcE [H]

Identifier: 17232112

GI number: 17232112

Start: 5522320

End: 5523882

Strand: Reverse

Name: yjcE [H]

Synonym: all4620

Alternate gene names: 17232112

Gene position: 5523882-5522320 (Counterclockwise)

Preceding gene: 17232114

Following gene: 17232110

Centisome position: 86.13

GC content: 42.61

Gene sequence:

>1563_bases
ATGGTACTTGAATCAGCAATCAGTGAAGAAGTGATCGCCACGAATCTCAAGCAGTTTCTTTTAGTACTTTCGGTTTCTTT
AGGTGTAGCCACCTTACCCCAAGTATTTAGTTGGTTTCGCCAAATCCCTTATACCTTACTTCTGGTAATTGTCGGTTTGG
GACTAGCAGTCGTTGATGTGCGCCTGGTTGTCCTGTCTCCTGCTTTAATTTTGTCTATCTTTTTACCACCCTTATTATTT
GAAGCCGCATGGAATTTGAAATGGTCAGATTTGCAGCGTGATTTTGTCCCAATTTGTCTATATGCCGTGTTTGGGGTGAT
AATCTCAATTGCCGGAGTAGCAATTGGACTTAATCAACTGGCGGGAATTTCCCTAACTACAGCGTTACTCATCGGTGCGA
GTCTTTCTGCTACTGACCCTGTTTCCGTCACCGCTTTGTTTCGTGAATTGGGTGTAGGAACTCGACTTGTCACCCTCATG
GAAGGCGAAAGCTTATTTAACGACGGGATGGCAGTAGTCGCCTTTGGTTTTTTGGTGGCTTTGCCTTTTGGGAATGCCGA
ATTAGGCTTTCAACCAATTTTGTTACAGCTTATACAAGTGGTGGGTATCGGTGTAGCAGTAGGCTGTTTGATTGGTTTTG
CTATTTCCTACCTGACCCAACGTTTTGACTTGCCAATGGTGGAACAGTCCTTAACTTTGGTGTCTGCTTACGGTACTTAT
CTCATTACCGAAGACTTGGGGGGTTCCGGCGTAATCGGGGTTGTCACTACAGGTTTGATATTAGGTAACTTTGGTTCACG
TATAGGCATGAATCCCCGGACTCGGATTATTGTTTCCGAATTTTGGGAATTTTTAGCGTTTTTTGTCAATTCGATTGTTT
TTTTATTAATTGGCGACCAAATCCGTTTTGCCAGTTTAGGAGAAAATCTGCAAATCATTGCTATTACAGTAGGTGCAATG
ATTTTAATGCGAGCAGTTGCATTATTTATTCTCAGCAAATTGAGCGTTATGATGACTCAATCACAAGTCTCCTTACCTGA
ACAGACTATTCTTTGGTGGGGTGGGTTACGTGGTTCTGTGTCAATTGCCCTGGCATTGAGTGTACCGAATGTATTGCCAG
GGCGAGAAAAAATCATTGCTACCGTCTTTGGAGTAGTTTTATTTACGCTACTAGTCCAGGGATTAACAATTAAACCCCTG
CTGCAAAAGCTCAATCTGCTCGGCGATGCACCCTTACGCGAACAGTATTTACAACTAGTCGCCCGTAGTGTTGCTCTAGA
AAGAGTATTGCAATACCTCCAAACAGAGAAACGTCCCGGTATCGACCCAGAGTTTATTCGTTACCAAGAGAAACTTGTCA
CAGGTGAAATTGCAGAATTGCAAACCAAGATTGATAAATTACACAATGAATACCCCAATCTTCAGAACTTTACAACAGAA
CAATTCCGCGATGAACTACTAGCAATTGAGGCAGATACTTATGCGGAATTTGTCAAGTCTGGGCGATTAAATAAAGAATT
GGCTCCGATGCTGGAAGATGTATTAGGTCATCAAAGAGACTAG

Upstream 100 bases:

>100_bases
TAAATATTCATGCCTAGATGATTAAAATCTTATATTCAGGCGATGCCATCTGAATATATTCCCTGGACAATCAGTACAGA
ATTCTACTAAATACTTACTC

Downstream 100 bases:

>100_bases
AGTTTAGAGACTAGCGCTCAGAAATTATCTCTTACCCAATCCCTATCTTTACTTCACAACAGCAGCAAAAGGACAACGGC
TAGTTTGTAAATTTGCTGGT

Product: Na+/H+-exchanging protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MVLESAISEEVIATNLKQFLLVLSVSLGVATLPQVFSWFRQIPYTLLLVIVGLGLAVVDVRLVVLSPALILSIFLPPLLF
EAAWNLKWSDLQRDFVPICLYAVFGVIISIAGVAIGLNQLAGISLTTALLIGASLSATDPVSVTALFRELGVGTRLVTLM
EGESLFNDGMAVVAFGFLVALPFGNAELGFQPILLQLIQVVGIGVAVGCLIGFAISYLTQRFDLPMVEQSLTLVSAYGTY
LITEDLGGSGVIGVVTTGLILGNFGSRIGMNPRTRIIVSEFWEFLAFFVNSIVFLLIGDQIRFASLGENLQIIAITVGAM
ILMRAVALFILSKLSVMMTQSQVSLPEQTILWWGGLRGSVSIALALSVPNVLPGREKIIATVFGVVLFTLLVQGLTIKPL
LQKLNLLGDAPLREQYLQLVARSVALERVLQYLQTEKRPGIDPEFIRYQEKLVTGEIAELQTKIDKLHNEYPNLQNFTTE
QFRDELLAIEADTYAEFVKSGRLNKELAPMLEDVLGHQRD

Sequences:

>Translated_520_residues
MVLESAISEEVIATNLKQFLLVLSVSLGVATLPQVFSWFRQIPYTLLLVIVGLGLAVVDVRLVVLSPALILSIFLPPLLF
EAAWNLKWSDLQRDFVPICLYAVFGVIISIAGVAIGLNQLAGISLTTALLIGASLSATDPVSVTALFRELGVGTRLVTLM
EGESLFNDGMAVVAFGFLVALPFGNAELGFQPILLQLIQVVGIGVAVGCLIGFAISYLTQRFDLPMVEQSLTLVSAYGTY
LITEDLGGSGVIGVVTTGLILGNFGSRIGMNPRTRIIVSEFWEFLAFFVNSIVFLLIGDQIRFASLGENLQIIAITVGAM
ILMRAVALFILSKLSVMMTQSQVSLPEQTILWWGGLRGSVSIALALSVPNVLPGREKIIATVFGVVLFTLLVQGLTIKPL
LQKLNLLGDAPLREQYLQLVARSVALERVLQYLQTEKRPGIDPEFIRYQEKLVTGEIAELQTKIDKLHNEYPNLQNFTTE
QFRDELLAIEADTYAEFVKSGRLNKELAPMLEDVLGHQRD
>Mature_520_residues
MVLESAISEEVIATNLKQFLLVLSVSLGVATLPQVFSWFRQIPYTLLLVIVGLGLAVVDVRLVVLSPALILSIFLPPLLF
EAAWNLKWSDLQRDFVPICLYAVFGVIISIAGVAIGLNQLAGISLTTALLIGASLSATDPVSVTALFRELGVGTRLVTLM
EGESLFNDGMAVVAFGFLVALPFGNAELGFQPILLQLIQVVGIGVAVGCLIGFAISYLTQRFDLPMVEQSLTLVSAYGTY
LITEDLGGSGVIGVVTTGLILGNFGSRIGMNPRTRIIVSEFWEFLAFFVNSIVFLLIGDQIRFASLGENLQIIAITVGAM
ILMRAVALFILSKLSVMMTQSQVSLPEQTILWWGGLRGSVSIALALSVPNVLPGREKIIATVFGVVLFTLLVQGLTIKPL
LQKLNLLGDAPLREQYLQLVARSVALERVLQYLQTEKRPGIDPEFIRYQEKLVTGEIAELQTKIDKLHNEYPNLQNFTTE
QFRDELLAIEADTYAEFVKSGRLNKELAPMLEDVLGHQRD

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI15529998, Length=391, Percent_Identity=25.8312020460358, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI41872703, Length=358, Percent_Identity=25.9776536312849, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI294997330, Length=371, Percent_Identity=27.7628032345013, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI110227626, Length=371, Percent_Identity=27.7628032345013, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI5454070, Length=369, Percent_Identity=27.9132791327913, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI148727259, Length=386, Percent_Identity=25.3886010362694, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI14211919, Length=412, Percent_Identity=26.4563106796117, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI27734935, Length=365, Percent_Identity=25.4794520547945, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI194239733, Length=388, Percent_Identity=26.8041237113402, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI27777632, Length=434, Percent_Identity=24.4239631336406, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4759144, Length=359, Percent_Identity=27.5766016713092, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790501, Length=538, Percent_Identity=26.5799256505576, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI25150332, Length=474, Percent_Identity=24.8945147679325, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71980847, Length=384, Percent_Identity=24.21875, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71999817, Length=411, Percent_Identity=27.007299270073, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71999819, Length=411, Percent_Identity=27.007299270073, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71999821, Length=384, Percent_Identity=27.0833333333333, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71993590, Length=362, Percent_Identity=27.9005524861878, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71993582, Length=362, Percent_Identity=27.9005524861878, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71990932, Length=397, Percent_Identity=24.1813602015113, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71990924, Length=397, Percent_Identity=24.1813602015113, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25147678, Length=392, Percent_Identity=25.765306122449, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71987537, Length=544, Percent_Identity=24.8161764705882, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71987535, Length=544, Percent_Identity=24.8161764705882, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71992107, Length=320, Percent_Identity=24.6875, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71992101, Length=320, Percent_Identity=24.6875, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71987559, Length=421, Percent_Identity=23.5154394299287, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71987545, Length=421, Percent_Identity=23.5154394299287, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320663, Length=340, Percent_Identity=25, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI281360447, Length=532, Percent_Identity=24.4360902255639, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221510734, Length=369, Percent_Identity=28.4552845528455, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI221510738, Length=369, Percent_Identity=28.4552845528455, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI221473215, Length=432, Percent_Identity=25.9259259259259, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221473212, Length=440, Percent_Identity=26.1363636363636, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281364513, Length=373, Percent_Identity=26.8096514745308, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI221473222, Length=373, Percent_Identity=26.8096514745308, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221510736, Length=373, Percent_Identity=28.4182305630027, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221510732, Length=373, Percent_Identity=28.4182305630027, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585580, Length=373, Percent_Identity=28.4182305630027, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585578, Length=373, Percent_Identity=28.4182305630027, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221510740, Length=373, Percent_Identity=28.4182305630027, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 56766; Mature: 56766

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]