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The map label for this gene is suhB [H]

Identifier: 17231953

GI number: 17231953

Start: 5345634

End: 5346440

Strand: Reverse

Name: suhB [H]

Synonym: all4461

Alternate gene names: 17231953

Gene position: 5346440-5345634 (Counterclockwise)

Preceding gene: 17231954

Following gene: 17231952

Centisome position: 83.36

GC content: 45.6

Gene sequence:

>807_bases
ATGAATGATTTTTGGACGACAATTCTCGATTTTGCCCAAACTACCACCACCAGAGTGGGCGCGCGATTAATGCAGGACTT
TGGGCAAGTGCAGGCTTTACAAAAAGCTGACGGTAGCTTGGTAACCCAAGCCGATAAATGGGCAGATCAAGAAATTCGAG
ATGCGATCGCCTCTACTTTTTCTGGTTATGGAATTTTAACTGAAGAAAGCGAACGCACATTTCCTGGGACAGAGTGGTGC
TGGGTTATAGATCCTTTAGATGGGACAACGAACTTTACACGAGGTATTCCCATCTGGTCGATTTCTCTGGCTTTGCTTTA
CCGAGGGACACCGATTTTTGGTTATGTTTATGCGCCACCCCTCAATCAAGCCTTTCATGGTTTTTGGCCTGGTACATCTG
GTTTAAGCACACCCTCTGGGGCATTTCTCAATCATCACCCAATTCATACCAGTAGTGATGCTCCCAGCAGCAATCATTTT
TTTAACCTTTGTTCCCGCAGTTTAGCTGTTGTCCAGAACGGATTTCCCTGCAAAATTCGGATGCTGGGTGTCGCTAGTTA
CAATTTCCTGACGGTTGCGGCTGGTGCAACATTAGGAGGGATAGAAGCAACACCAAAAGTTTGGGACATAGCAGGCGCTT
GGGTAATTGTCCAAGCTGCTGGTGGTAGCTGGGTTTCCCTCGACTCAGAAGCGTTTCCTTTGTCAGACGGGGAAGATTAT
AGCGATCGCTCTTTCCCTACTCTCGTTGTTAGTCGCTCAGACTTAGTTACATTTTTTACACCCTTAATTAAAGATGTAAA
AATTTAA

Upstream 100 bases:

>100_bases
TCCTGAACCGAGTTAGCGTGAAGGAATTTCAAACTACCACCAAGAAAGCGATCGCTTCTGTTTTAGAAAGTGATTTAGAT
TAGAACGTGAGAACTTATTG

Downstream 100 bases:

>100_bases
CTCACCCAATACTTTTTTATCAACCCAGGTTGCCTGTAATCACAAAAAATTTTACAGGCGACCTGGGTAATTTTTCTGGA
TATGAGATTTTTTCGACGTA

Product: inositol monophosphate family protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNDFWTTILDFAQTTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTFSGYGILTEESERTFPGTEWC
WVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPPLNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHF
FNLCSRSLAVVQNGFPCKIRMLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEAFPLSDGEDY
SDRSFPTLVVSRSDLVTFFTPLIKDVKI

Sequences:

>Translated_268_residues
MNDFWTTILDFAQTTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTFSGYGILTEESERTFPGTEWC
WVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPPLNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHF
FNLCSRSLAVVQNGFPCKIRMLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEAFPLSDGEDY
SDRSFPTLVVSRSDLVTFFTPLIKDVKI
>Mature_268_residues
MNDFWTTILDFAQTTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTFSGYGILTEESERTFPGTEWC
WVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPPLNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHF
FNLCSRSLAVVQNGFPCKIRMLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEAFPLSDGEDY
SDRSFPTLVVSRSDLVTFFTPLIKDVKI

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=253, Percent_Identity=24.901185770751, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=24.901185770751, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1788882, Length=243, Percent_Identity=29.6296296296296, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193202572, Length=235, Percent_Identity=27.2340425531915, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193202570, Length=212, Percent_Identity=27.8301886792453, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320493, Length=222, Percent_Identity=30.6306306306306, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357329, Length=280, Percent_Identity=28.2142857142857, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24664926, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24664922, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29202; Mature: 29202

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFWTTILDFAQTTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHH
SGYGILTEESERTFPGTEWCWVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPP
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHEEHEECCCCEEEEEECCC
LNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHFFNLCSRSLAVVQNGFPCKIR
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
MLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEAFPLSDGEDY
EEEEECCCEEEEECCCEECCCCCCCCEEEECCEEEEEEECCCCEEEECCCCCCCCCCCCC
SDRSFPTLVVSRSDLVTFFTPLIKDVKI
CCCCCCEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDFWTTILDFAQTTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHH
SGYGILTEESERTFPGTEWCWVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPP
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHEEHEECCCCEEEEEECCC
LNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHFFNLCSRSLAVVQNGFPCKIR
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
MLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEAFPLSDGEDY
EEEEECCCEEEEECCCEECCCCCCCCEEEECCEEEEEEECCCCEEEECCCCCCCCCCCCC
SDRSFPTLVVSRSDLVTFFTPLIKDVKI
CCCCCCEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]