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The map label for this gene is crp [C]

Identifier: 17231946

GI number: 17231946

Start: 5339390

End: 5340070

Strand: Direct

Name: crp [C]

Synonym: alr4454

Alternate gene names: 17231946

Gene position: 5339390-5340070 (Clockwise)

Preceding gene: 17231941

Following gene: 17231947

Centisome position: 83.25

GC content: 41.56

Gene sequence:

>681_bases
GTGGGGAGTAGTGAATGGGGAGTAATTCTTGTTACTTCTATAATTTTAGTCAAGTACATGATCAATTTTTTAAACATTGA
CCATCTGCCAGAAAATATCAAAATGGCGATGGCAATCACCTATGAGAGTTTAACGGCTGGACAGCCGCTTTTCCATCAAG
GAGATTTAACCAGAGCCATTTTTGTAGTCATATCTGGACAGATCAGACTCATGCACTATACCGACGCTGGTCAATCCATC
AAGCACTATGAAGTCAAAGCTGGAGAGAGTTTTGCAGAAGCTGCATTGTTCAATGAGTTTTATGATTGTACAGCGATCGC
TGATATTCCTTCCCGTGTCGCTACTTTTCCTAAACAGGCGTTTCTAGCAACTTTGCGCCAATATCCAGATTTATCAGAGG
CTCTCATAGTACAACTGGCACGAAGATTTCACCAAGTAAAAATCTTACTAGAACTACGGAGTATTCGTTCTGCGCGCGAT
CGCGTGCTGCGTTATTTGGAAATTTCCGCCCATCCACACGGAAACACCGTCAATCTGGATAAACCTCTGAAAGAAATAGC
CGAAGATATGGGATTGAGCCAGGAAGCATTGTCTCGCGTTTTGAGTCAACTGCAAAAAGACGGGACAATTACCCGCAAAA
AACGACAAATTGTATTAATTCAAGAATTAAATCGAACTTAA

Upstream 100 bases:

>100_bases
ACACCAAGAAAATCCACCCCCAAAGCGAAACCTCGTCGCCAAATATCAGCTTTGGGGTAATATTTTTTGGGGATACGTTC
GATGGTCATAAAAATGGGGG

Downstream 100 bases:

>100_bases
TCGCAAAATTACGGAATATTAAAAATCATCTCAAACTTGATTTCAATCAAAGAAGTCTCTGTGACGAAAGCATAGATTTA
GCTACGGAAATCTGACGCTA

Product: transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; FNR-Like Transcriptional Regulator; Transcription Regulator; Transcriptional Regulator DnrS; CRP Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator NNR Like; DnrE Protein; Crp-Like Transcriptional Regulator; Fnr-Like Transcriptional Activator; Dnr-Like Transcriptional Activator; CAMP-Bindin Transcriptional Regulator; Transcriptional Regulator Dnr

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGSSEWGVILVTSIILVKYMINFLNIDHLPENIKMAMAITYESLTAGQPLFHQGDLTRAIFVVISGQIRLMHYTDAGQSI
KHYEVKAGESFAEAALFNEFYDCTAIADIPSRVATFPKQAFLATLRQYPDLSEALIVQLARRFHQVKILLELRSIRSARD
RVLRYLEISAHPHGNTVNLDKPLKEIAEDMGLSQEALSRVLSQLQKDGTITRKKRQIVLIQELNRT

Sequences:

>Translated_226_residues
MGSSEWGVILVTSIILVKYMINFLNIDHLPENIKMAMAITYESLTAGQPLFHQGDLTRAIFVVISGQIRLMHYTDAGQSI
KHYEVKAGESFAEAALFNEFYDCTAIADIPSRVATFPKQAFLATLRQYPDLSEALIVQLARRFHQVKILLELRSIRSARD
RVLRYLEISAHPHGNTVNLDKPLKEIAEDMGLSQEALSRVLSQLQKDGTITRKKRQIVLIQELNRT
>Mature_225_residues
GSSEWGVILVTSIILVKYMINFLNIDHLPENIKMAMAITYESLTAGQPLFHQGDLTRAIFVVISGQIRLMHYTDAGQSIK
HYEVKAGESFAEAALFNEFYDCTAIADIPSRVATFPKQAFLATLRQYPDLSEALIVQLARRFHQVKILLELRSIRSARDR
VLRYLEISAHPHGNTVNLDKPLKEIAEDMGLSQEALSRVLSQLQKDGTITRKKRQIVLIQELNRT

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25609; Mature: 25478

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSEWGVILVTSIILVKYMINFLNIDHLPENIKMAMAITYESLTAGQPLFHQGDLTRAI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCCCCCCCHHHHH
FVVISGQIRLMHYTDAGQSIKHYEVKAGESFAEAALFNEFYDCTAIADIPSRVATFPKQA
HEEEECCEEEEEECCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FLATLRQYPDLSEALIVQLARRFHQVKILLELRSIRSARDRVLRYLEISAHPHGNTVNLD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCH
KPLKEIAEDMGLSQEALSRVLSQLQKDGTITRKKRQIVLIQELNRT
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCCC
>Mature Secondary Structure 
GSSEWGVILVTSIILVKYMINFLNIDHLPENIKMAMAITYESLTAGQPLFHQGDLTRAI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCCCCCCCHHHHH
FVVISGQIRLMHYTDAGQSIKHYEVKAGESFAEAALFNEFYDCTAIADIPSRVATFPKQA
HEEEECCEEEEEECCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FLATLRQYPDLSEALIVQLARRFHQVKILLELRSIRSARDRVLRYLEISAHPHGNTVNLD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCH
KPLKEIAEDMGLSQEALSRVLSQLQKDGTITRKKRQIVLIQELNRT
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA