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The map label for this gene is spoVK [H]

Identifier: 17231725

GI number: 17231725

Start: 5069431

End: 5070903

Strand: Reverse

Name: spoVK [H]

Synonym: all4233

Alternate gene names: 17231725

Gene position: 5070903-5069431 (Counterclockwise)

Preceding gene: 17231726

Following gene: 17231723

Centisome position: 79.06

GC content: 41.62

Gene sequence:

>1473_bases
ATGCTGATTTTTGAAGAGCATTTTCAAGACAATCGCTGTAGCTGGGTAACACGAGATAGTGAAGAGTGTAGCCTTTGCAT
GGACGTGAGTCATTATGTATTTGACCATAAACGTGCAGGTGATACATATTGGCTATCGTGGAACTCAGCCGAGTTCTTTT
ATGAGAGAACGAATTTTCATATTCATATAGTTCTAGAAAAAGCTGCTGGTGTAGATGATCATGGTTATGGTTTTGTCTGG
GGATTGTCAGACGTTAGCAATTTCTTTGAGTTCGTGATTTCGGGCAATGGTCACTATCGCATCACGGAAATCAAAGATGG
TAACTTTATTAATTACACAGATTGGAAAAGGTGCGATCGCATTCACCGTAGTGACTCGGTTAACCTTTTAGAAATTACCC
GTGTGGGTAATATGGTAGAGTTCTATATCAACAGTACTTTAGTAGATAAATTTCCTGCCGATAAGTTAGTTGATGTCTCA
GGGAAAAATTTTGGTTTTGTGATTCATGACAAAATCAAAATGAAAGTCCATAGTTTAATTGTCAGCGCTCCCGATACGGA
AAAAGAATCGGTTGATAGTCATAGTGATACTCGTGATTCTAAGCAGGAGACAAAAGCCTCTTTTGTTGAGCATGACCCCC
CAGAAAAGGATACTGTAGAAGCTGTGTTTGCAGACTTAAAGGCATTAGTTGGGCATGAGCAAACTAAACATCAACTTTTC
TCCTTAGCCAACTACTTGAAAGTACAAACGGAACGGAGAAAACGAGGACTAAAAATAGTAGACACTTCACTACACCTAAT
GCTTTACGGCCCCCCAGGTACAGGTAAGACGACCATCGCCCGTTTGGTAGGGCGTTTATATAAACAAATGGGATTTTTTC
CACGGGGACACGTTGTTGAAACCGATCGCGCCGGCATCATTGGCGGTTATATTGGACAAACTGCCCTACGAATGGAAAGT
GCTGTACACCAAGCCATCGGCGGTGTTTTGTTCATTGACGAAGCCCACGCCTTAGCGGCTGAAGATACCCCTAGCGATTT
TGGCAAGGAAGCATTGCAGATATTAATTAAACGCATGGAAGATTACCGCGATCACATGGCTGTGGTTGTCGCCGGCTACA
CTGATGAAATGGATCGCTTATTAGAGTTAAACCCCGGTTTTAAATCACGGTTAAATCGGTTATTTTATCTTGATCACTAC
ACTCCCAATCAGTTGCTATTGATTTTCAAGAAATTCTGTCAAGACAACGGTTATATTTTAGACTCCTCAGCCATTATCGT
GCTGCAAGCCACCTTTGAGGTCGCCTACGCCAAACGGGACAAAAGTTTTGGTAATGGACGCTTTGCGCGGGCGCTATTTG
AACGCAGCATTGAACAACAAGCTAACCGCATCGTTACACATTTACAAGAGTTAGATGATTACGAAATTAACTTGATTCTT
GCTGAAGATTTGTCTTTTATAGAATTCAAATAG

Upstream 100 bases:

>100_bases
GGCTCTTCTGCCAGGGAGAGGGGTTATAAAATCATAAAACCTCTTGTTAGAGTGAAATAGCTAGCAGCTGATTTTACACA
CAGAGCTACAGAGGAACGCA

Downstream 100 bases:

>100_bases
TGGGCTGTCATCTCTAACCCAAAAATAGCTTATAGGCTGGGTTCTGGCTTTCATCCCAATACTGGTAGCCGAGGGAATCG
AGAAATGCTTGCCATTCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MLIFEEHFQDNRCSWVTRDSEECSLCMDVSHYVFDHKRAGDTYWLSWNSAEFFYERTNFHIHIVLEKAAGVDDHGYGFVW
GLSDVSNFFEFVISGNGHYRITEIKDGNFINYTDWKRCDRIHRSDSVNLLEITRVGNMVEFYINSTLVDKFPADKLVDVS
GKNFGFVIHDKIKMKVHSLIVSAPDTEKESVDSHSDTRDSKQETKASFVEHDPPEKDTVEAVFADLKALVGHEQTKHQLF
SLANYLKVQTERRKRGLKIVDTSLHLMLYGPPGTGKTTIARLVGRLYKQMGFFPRGHVVETDRAGIIGGYIGQTALRMES
AVHQAIGGVLFIDEAHALAAEDTPSDFGKEALQILIKRMEDYRDHMAVVVAGYTDEMDRLLELNPGFKSRLNRLFYLDHY
TPNQLLLIFKKFCQDNGYILDSSAIIVLQATFEVAYAKRDKSFGNGRFARALFERSIEQQANRIVTHLQELDDYEINLIL
AEDLSFIEFK

Sequences:

>Translated_490_residues
MLIFEEHFQDNRCSWVTRDSEECSLCMDVSHYVFDHKRAGDTYWLSWNSAEFFYERTNFHIHIVLEKAAGVDDHGYGFVW
GLSDVSNFFEFVISGNGHYRITEIKDGNFINYTDWKRCDRIHRSDSVNLLEITRVGNMVEFYINSTLVDKFPADKLVDVS
GKNFGFVIHDKIKMKVHSLIVSAPDTEKESVDSHSDTRDSKQETKASFVEHDPPEKDTVEAVFADLKALVGHEQTKHQLF
SLANYLKVQTERRKRGLKIVDTSLHLMLYGPPGTGKTTIARLVGRLYKQMGFFPRGHVVETDRAGIIGGYIGQTALRMES
AVHQAIGGVLFIDEAHALAAEDTPSDFGKEALQILIKRMEDYRDHMAVVVAGYTDEMDRLLELNPGFKSRLNRLFYLDHY
TPNQLLLIFKKFCQDNGYILDSSAIIVLQATFEVAYAKRDKSFGNGRFARALFERSIEQQANRIVTHLQELDDYEINLIL
AEDLSFIEFK
>Mature_490_residues
MLIFEEHFQDNRCSWVTRDSEECSLCMDVSHYVFDHKRAGDTYWLSWNSAEFFYERTNFHIHIVLEKAAGVDDHGYGFVW
GLSDVSNFFEFVISGNGHYRITEIKDGNFINYTDWKRCDRIHRSDSVNLLEITRVGNMVEFYINSTLVDKFPADKLVDVS
GKNFGFVIHDKIKMKVHSLIVSAPDTEKESVDSHSDTRDSKQETKASFVEHDPPEKDTVEAVFADLKALVGHEQTKHQLF
SLANYLKVQTERRKRGLKIVDTSLHLMLYGPPGTGKTTIARLVGRLYKQMGFFPRGHVVETDRAGIIGGYIGQTALRMES
AVHQAIGGVLFIDEAHALAAEDTPSDFGKEALQILIKRMEDYRDHMAVVVAGYTDEMDRLLELNPGFKSRLNRLFYLDHY
TPNQLLLIFKKFCQDNGYILDSSAIIVLQATFEVAYAKRDKSFGNGRFARALFERSIEQQANRIVTHLQELDDYEINLIL
AEDLSFIEFK

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR014232 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 56188; Mature: 56188

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFEEHFQDNRCSWVTRDSEECSLCMDVSHYVFDHKRAGDTYWLSWNSAEFFYERTNFH
CEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCEE
IHIVLEKAAGVDDHGYGFVWGLSDVSNFFEFVISGNGHYRITEIKDGNFINYTDWKRCDR
EEEEEEECCCCCCCCCEEEEEHHHHHHHHHEEECCCCCEEEEEECCCCEECCCCHHHHHH
IHRSDSVNLLEITRVGNMVEFYINSTLVDKFPADKLVDVSGKNFGFVIHDKIKMKVHSLI
HHCCCCCCEEEEEHHCCEEEEEECCHHHCCCCCCCEEECCCCCEEEEEEHHHHHEEEEHE
VSAPDTEKESVDSHSDTRDSKQETKASFVEHDPPEKDTVEAVFADLKALVGHEQTKHQLF
EECCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
SLANYLKVQTERRKRGLKIVDTSLHLMLYGPPGTGKTTIARLVGRLYKQMGFFPRGHVVE
HHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEE
TDRAGIIGGYIGQTALRMESAVHQAIGGVLFIDEAHALAAEDTPSDFGKEALQILIKRME
CCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
DYRDHMAVVVAGYTDEMDRLLELNPGFKSRLNRLFYLDHYTPNQLLLIFKKFCQDNGYIL
HHHCCEEEEEECCHHHHHHHHCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
DSSAIIVLQATFEVAYAKRDKSFGNGRFARALFERSIEQQANRIVTHLQELDDYEINLIL
ECCEEEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AEDLSFIEFK
ECCCCCEECC
>Mature Secondary Structure
MLIFEEHFQDNRCSWVTRDSEECSLCMDVSHYVFDHKRAGDTYWLSWNSAEFFYERTNFH
CEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCEE
IHIVLEKAAGVDDHGYGFVWGLSDVSNFFEFVISGNGHYRITEIKDGNFINYTDWKRCDR
EEEEEEECCCCCCCCCEEEEEHHHHHHHHHEEECCCCCEEEEEECCCCEECCCCHHHHHH
IHRSDSVNLLEITRVGNMVEFYINSTLVDKFPADKLVDVSGKNFGFVIHDKIKMKVHSLI
HHCCCCCCEEEEEHHCCEEEEEECCHHHCCCCCCCEEECCCCCEEEEEEHHHHHEEEEHE
VSAPDTEKESVDSHSDTRDSKQETKASFVEHDPPEKDTVEAVFADLKALVGHEQTKHQLF
EECCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
SLANYLKVQTERRKRGLKIVDTSLHLMLYGPPGTGKTTIARLVGRLYKQMGFFPRGHVVE
HHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEE
TDRAGIIGGYIGQTALRMESAVHQAIGGVLFIDEAHALAAEDTPSDFGKEALQILIKRME
CCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
DYRDHMAVVVAGYTDEMDRLLELNPGFKSRLNRLFYLDHYTPNQLLLIFKKFCQDNGYIL
HHHCCEEEEEECCHHHHHHHHCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
DSSAIIVLQATFEVAYAKRDKSFGNGRFARALFERSIEQQANRIVTHLQELDDYEINLIL
ECCEEEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AEDLSFIEFK
ECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1787791; 9384377 [H]