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The map label for this gene is sasA [H]

Identifier: 17231588

GI number: 17231588

Start: 4934422

End: 4935492

Strand: Reverse

Name: sasA [H]

Synonym: all4096

Alternate gene names: 17231588

Gene position: 4935492-4934422 (Counterclockwise)

Preceding gene: 17231589

Following gene: 17231584

Centisome position: 76.95

GC content: 40.62

Gene sequence:

>1071_bases
ATGGAAACTCAACCATCCATTTTGGTGATTGATGATGAACCGGATAACTTTGATGTTGTAGAAACATTGCTAGATGGCGA
AAACTATCAGTTGCATTATGCTTCTGGTGGTCAACAAGCGATCGCTCGCCTCAGCAGTTTTCAGCCGGATGTGATTTTGC
TAGATGTGATGATGCCTCATTTAGATGGGATAGAAGTATGCCGACGCATTAAAGCTGATCCCCAGTGGCAGGCAGTACCC
ATTATTATTGTCACAGCATTAACTGCTAAAGAAGACCTGGCTCACTGTTTGAACGCAGGAGCAGATGACTTTATTAGTAA
GCCTCTCAACAGCGTAGAGTTAAGAGCTAGAGTTAATTCTATGTTGCGGATTAAGCAACAGCATGATAACTTGCAAGGTT
TACTTAAATTGCAGGAAGACATGGTTAATATGATTGTCCATGACCTGCGAAATCCTCTAGCCAGTATTGTGATCTCAACA
GAAATGCTCAAATTTCCTAGTTTGCCACCAGACAAACAGCAACAAAAAGTAAGTCAAATAGCGATCGCCTGTCAACAACT
ACAAACCCTGATTGATAGCCTATTGACCATGGCCAAGCTAGAATCCGGTAAAATGGTGCTTAACTATACAGAGATAGACC
TTTGTGCTATTTGTATATCAGCCTTAGCAGATATTGAAGATATTGCTGCTCAAAAGCGTCTGAGGCTCATCAGCGAATTA
CCAGAACCGGGTGGTATGGTCAAAATAGATGCAGCTATTTTTCGCCGAGTACTAGATAATCTGCTCTCTAATGCAATTAA
GTTTTCACCATCAAACGCACGGGTAATTCTCAAAGCAGCGTATTTAGAAACAGGTGCGAAATTACAGGTGATTGATTCAG
GTAAAGGAATTTCTCAAGAATTAAGGCACAGCATTTTCCAGAAGTATGAAATCGGCAATATAGTGTCCGAAGTTTCCCAA
CTTGGTCTAGGATTAGCATTTTGTAAAATGGCAATAGAAGCACACAATGGCACGATTACTATCGAAGATAATCATCCCCA
AGGTTCTATTTTTACAGTCTTAATTCCCTAA

Upstream 100 bases:

>100_bases
AAAACCATCAGGAACTACATACATCAAAATACCGGAAGAGTGACTAGGAAAAGTTTTCCCTACTCAGCACTATTTTCAAC
TTAGTCAGGAAGTATTCTAA

Downstream 100 bases:

>100_bases
GAATAAATATTTTTAACCTTTCTCTCGATTAATCCAAACACCCCTTAACCCGGCTGCTTTTGCTCCTTGATAATCTTCTT
CAATACTATCGCCAATGTGC

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
METQPSILVIDDEPDNFDVVETLLDGENYQLHYASGGQQAIARLSSFQPDVILLDVMMPHLDGIEVCRRIKADPQWQAVP
IIIVTALTAKEDLAHCLNAGADDFISKPLNSVELRARVNSMLRIKQQHDNLQGLLKLQEDMVNMIVHDLRNPLASIVIST
EMLKFPSLPPDKQQQKVSQIAIACQQLQTLIDSLLTMAKLESGKMVLNYTEIDLCAICISALADIEDIAAQKRLRLISEL
PEPGGMVKIDAAIFRRVLDNLLSNAIKFSPSNARVILKAAYLETGAKLQVIDSGKGISQELRHSIFQKYEIGNIVSEVSQ
LGLGLAFCKMAIEAHNGTITIEDNHPQGSIFTVLIP

Sequences:

>Translated_356_residues
METQPSILVIDDEPDNFDVVETLLDGENYQLHYASGGQQAIARLSSFQPDVILLDVMMPHLDGIEVCRRIKADPQWQAVP
IIIVTALTAKEDLAHCLNAGADDFISKPLNSVELRARVNSMLRIKQQHDNLQGLLKLQEDMVNMIVHDLRNPLASIVIST
EMLKFPSLPPDKQQQKVSQIAIACQQLQTLIDSLLTMAKLESGKMVLNYTEIDLCAICISALADIEDIAAQKRLRLISEL
PEPGGMVKIDAAIFRRVLDNLLSNAIKFSPSNARVILKAAYLETGAKLQVIDSGKGISQELRHSIFQKYEIGNIVSEVSQ
LGLGLAFCKMAIEAHNGTITIEDNHPQGSIFTVLIP
>Mature_356_residues
METQPSILVIDDEPDNFDVVETLLDGENYQLHYASGGQQAIARLSSFQPDVILLDVMMPHLDGIEVCRRIKADPQWQAVP
IIIVTALTAKEDLAHCLNAGADDFISKPLNSVELRARVNSMLRIKQQHDNLQGLLKLQEDMVNMIVHDLRNPLASIVIST
EMLKFPSLPPDKQQQKVSQIAIACQQLQTLIDSLLTMAKLESGKMVLNYTEIDLCAICISALADIEDIAAQKRLRLISEL
PEPGGMVKIDAAIFRRVLDNLLSNAIKFSPSNARVILKAAYLETGAKLQVIDSGKGISQELRHSIFQKYEIGNIVSEVSQ
LGLGLAFCKMAIEAHNGTITIEDNHPQGSIFTVLIP

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=30.2222222222222, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788713, Length=216, Percent_Identity=31.4814814814815, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786911, Length=118, Percent_Identity=35.5932203389831, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=29.957805907173, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788394, Length=131, Percent_Identity=35.8778625954198, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=29.4605809128631, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=28.4584980237154, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=34.1880341880342, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789809, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=120, Percent_Identity=32.5, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.9915966386555, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=35.042735042735, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=266, Percent_Identity=24.0601503759398, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=24.1228070175439, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=28.125, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788393, Length=272, Percent_Identity=25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=31.0924369747899, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=219, Percent_Identity=29.2237442922374, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082012, Length=179, Percent_Identity=25.1396648044693, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789402, Length=117, Percent_Identity=29.9145299145299, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=29.0598290598291, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787375, Length=95, Percent_Identity=30.5263157894737, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=20.253164556962, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 39279; Mature: 39279

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQPSILVIDDEPDNFDVVETLLDGENYQLHYASGGQQAIARLSSFQPDVILLDVMMPH
CCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCEEEHHHHHCC
LDGIEVCRRIKADPQWQAVPIIIVTALTAKEDLAHCLNAGADDFISKPLNSVELRARVNS
CCHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
MLRIKQQHDNLQGLLKLQEDMVNMIVHDLRNPLASIVISTEMLKFPSLPPDKQQQKVSQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AIACQQLQTLIDSLLTMAKLESGKMVLNYTEIDLCAICISALADIEDIAAQKRLRLISEL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEPGGMVKIDAAIFRRVLDNLLSNAIKFSPSNARVILKAAYLETGAKLQVIDSGKGISQE
CCCCCEEEEHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEEEEECCCCHHHH
LRHSIFQKYEIGNIVSEVSQLGLGLAFCKMAIEAHNGTITIEDNHPQGSIFTVLIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCCEEEEEEC
>Mature Secondary Structure
METQPSILVIDDEPDNFDVVETLLDGENYQLHYASGGQQAIARLSSFQPDVILLDVMMPH
CCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCEEEHHHHHCC
LDGIEVCRRIKADPQWQAVPIIIVTALTAKEDLAHCLNAGADDFISKPLNSVELRARVNS
CCHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
MLRIKQQHDNLQGLLKLQEDMVNMIVHDLRNPLASIVISTEMLKFPSLPPDKQQQKVSQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AIACQQLQTLIDSLLTMAKLESGKMVLNYTEIDLCAICISALADIEDIAAQKRLRLISEL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEPGGMVKIDAAIFRRVLDNLLSNAIKFSPSNARVILKAAYLETGAKLQVIDSGKGISQE
CCCCCEEEEHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEEEEECCCCHHHH
LRHSIFQKYEIGNIVSEVSQLGLGLAFCKMAIEAHNGTITIEDNHPQGSIFTVLIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA