Click here to switch to the map view.

The map label for this gene is tktB [C]

Identifier: 17231544

GI number: 17231544

Start: 4877766

End: 4879667

Strand: Reverse

Name: tktB [C]

Synonym: all4052

Alternate gene names: 17231544

Gene position: 4879667-4877766 (Counterclockwise)

Preceding gene: 17231545

Following gene: 17231543

Centisome position: 76.08

GC content: 47.27

Gene sequence:

>1902_bases
ATGACTATACAAGAGCAACTACACCAATGGCATGAATTAGCGCAACAATTGCGAATAGATAGTATTCGCGCCACAACTGG
CGCTACTTCAGGCCACCCTACTTCTTCCATGTCCCCTGCCGATTTAATGGCGGTTTTATTAACTAATTATCTTCACTACG
ATTTTGACAATCCACATCACCCTAATAACGATCGCTTTATTCTCTCAAAAGGACACGCTGCACCCTTACTTTACGCCATG
TATAAAGCGGCTGGGGTCATCACTGATGAGGAATTAATGTCACTACGACAAATGGGCAGCCGTCTGGAAGGTCATCCCAC
ACCGGTATTACCTTGGGTGGATGTGGCGACTGGTTCCTTAGGGCAAGGATTACCCATCGGTGTGGGGTTGGGGTTAGCGG
GGAAATATTTAGACCAGCTACCTTATAACGTCTGGGTGTTATTAGGTGACAGTGAAACAGCCGAAGGTTCAGTGTGGGAA
GCTTTCGACCATGCCGCACACTACACCCTAGACAACCTCATTGCCATTATCGATGTTAACCGCCTTGGTCAACGGGGTCA
GACAGAACTAGGCTGGAATACTCAAGCCTATGCTAATCGTGCCAAGGCTTTTGGTTGGCAAGCAATAGAAATAGATGGTC
ACGATTTGACGGAAATTGACCAAGCCTTTAGCGCTGCTGTCAGTATTAACGATCGCCCCACTGTAATTATTGCCCGTACC
AAAAAAGGTAAAGGCGTAGCATCTTTGGAAGATTTGGGTGGGTGGCATGGCAAAGCTTTAAAGCCTGATGCAGCAAAACA
AGCGATCGCTGAATTAGGTGGTGAACGTCAGATTACTATTCAAGTAGCCAAACCGGAGCCAGAACAACCCGCATTAGCTA
ACCCCCAACCCTTCCAACTACCAACCTATGAACAAGGTGCAGAAGTTGCCACCCGTCGCGCCTATGGTGATGCTCTCAAA
GCCTTAGGTGCTGCTCAACCTGATGTTGTTGCCCTGGATGCAGAGGTGAGCAATTCCACTTACACTGAAGATTTTGCCGA
AGCTTACCCAGAAAGATACTTTGAGATGTACATTGCCGAACAGCAAATGGTTGCAGCTGCTGTTGGCTTGCAAGTACGCC
AGTATAAACCCTTTGCTTCGACCTTCGCCGCCTTCTTAAGTCGTGCCTACGACTTTGTGAGGATGGCTGCTGTCTCTCGC
GCCAATATTAAATTAGTGGGTTCCCACGCGGGTGTATCCATTGGTCAAGACGGCCCTTCACAAATGGCATTGGAAGACTT
AGCCGCCTTTCGAGCAGTGTGGAATAGTACCGTACTCTACCCCTGTGATGCCAATCAAACAGCGAAATTAGTAGAACAGA
TGAGCGATCTCCAGGGTATTGTTTATCTGCGTACCACCAGAGAAAATACACCAGTGATCTACGGAACTGAAGAAGATTTT
CCCATCGGCGGCAGTAAAGTTATTCGTAGTTCCGACCAAGACCAAGCCACCATCATTGGTGCAGGTATAACTTTACACGA
AGCCATCAAAGCAGGCGATCACCTCAAAAACGAAGGCATTATAGTCCGCATCATCGATGCTTACTCTGTTAAACCCATTG
ACGTAAAGACTCTGCATCAAGCAGCCAATGACACAGAAGGCAATTTAGTAGTCGTCGAAGACCATTGGCATGAAGGCGGA
TTAGGTGCAGCCGTACTGGATGCCTTTGCTGGTGTTGGTAACCTTTCTAGCTACGATGGCCCTCCATTGCAACTAATTAA
GTTAGCAGTTCATAATATGCCAGGTTCTGGCACACCAGAAGAATTACTCCATGCAGCCAAAATTGACGCTGATGCGATCG
TCGAAGCCGTAAAATTGCAAGTCAGACATCCTATTGGTGCCAGAATTTCAATACATCCTTAA

Upstream 100 bases:

>100_bases
ACATAATAAGAATCTATTTAACTTTCACATCTTTTCGTGTTGGCTGTCAACTGTTAACAAACCATACAAGTGACTATGTA
ATTTAAAAGCTTCATAGCTT

Downstream 100 bases:

>100_bases
TAAAATCTGTCAACTGACTTCAGTCGTCAGCCAGAGGGAAACGAGACAAAACTTTTTTAAGCTGATAGACAGATTATTCT
ATCTTGCACAATTGGTAACA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTIQEQLHQWHELAQQLRIDSIRATTGATSGHPTSSMSPADLMAVLLTNYLHYDFDNPHHPNNDRFILSKGHAAPLLYAM
YKAAGVITDEELMSLRQMGSRLEGHPTPVLPWVDVATGSLGQGLPIGVGLGLAGKYLDQLPYNVWVLLGDSETAEGSVWE
AFDHAAHYTLDNLIAIIDVNRLGQRGQTELGWNTQAYANRAKAFGWQAIEIDGHDLTEIDQAFSAAVSINDRPTVIIART
KKGKGVASLEDLGGWHGKALKPDAAKQAIAELGGERQITIQVAKPEPEQPALANPQPFQLPTYEQGAEVATRRAYGDALK
ALGAAQPDVVALDAEVSNSTYTEDFAEAYPERYFEMYIAEQQMVAAAVGLQVRQYKPFASTFAAFLSRAYDFVRMAAVSR
ANIKLVGSHAGVSIGQDGPSQMALEDLAAFRAVWNSTVLYPCDANQTAKLVEQMSDLQGIVYLRTTRENTPVIYGTEEDF
PIGGSKVIRSSDQDQATIIGAGITLHEAIKAGDHLKNEGIIVRIIDAYSVKPIDVKTLHQAANDTEGNLVVVEDHWHEGG
LGAAVLDAFAGVGNLSSYDGPPLQLIKLAVHNMPGSGTPEELLHAAKIDADAIVEAVKLQVRHPIGARISIHP

Sequences:

>Translated_633_residues
MTIQEQLHQWHELAQQLRIDSIRATTGATSGHPTSSMSPADLMAVLLTNYLHYDFDNPHHPNNDRFILSKGHAAPLLYAM
YKAAGVITDEELMSLRQMGSRLEGHPTPVLPWVDVATGSLGQGLPIGVGLGLAGKYLDQLPYNVWVLLGDSETAEGSVWE
AFDHAAHYTLDNLIAIIDVNRLGQRGQTELGWNTQAYANRAKAFGWQAIEIDGHDLTEIDQAFSAAVSINDRPTVIIART
KKGKGVASLEDLGGWHGKALKPDAAKQAIAELGGERQITIQVAKPEPEQPALANPQPFQLPTYEQGAEVATRRAYGDALK
ALGAAQPDVVALDAEVSNSTYTEDFAEAYPERYFEMYIAEQQMVAAAVGLQVRQYKPFASTFAAFLSRAYDFVRMAAVSR
ANIKLVGSHAGVSIGQDGPSQMALEDLAAFRAVWNSTVLYPCDANQTAKLVEQMSDLQGIVYLRTTRENTPVIYGTEEDF
PIGGSKVIRSSDQDQATIIGAGITLHEAIKAGDHLKNEGIIVRIIDAYSVKPIDVKTLHQAANDTEGNLVVVEDHWHEGG
LGAAVLDAFAGVGNLSSYDGPPLQLIKLAVHNMPGSGTPEELLHAAKIDADAIVEAVKLQVRHPIGARISIHP
>Mature_632_residues
TIQEQLHQWHELAQQLRIDSIRATTGATSGHPTSSMSPADLMAVLLTNYLHYDFDNPHHPNNDRFILSKGHAAPLLYAMY
KAAGVITDEELMSLRQMGSRLEGHPTPVLPWVDVATGSLGQGLPIGVGLGLAGKYLDQLPYNVWVLLGDSETAEGSVWEA
FDHAAHYTLDNLIAIIDVNRLGQRGQTELGWNTQAYANRAKAFGWQAIEIDGHDLTEIDQAFSAAVSINDRPTVIIARTK
KGKGVASLEDLGGWHGKALKPDAAKQAIAELGGERQITIQVAKPEPEQPALANPQPFQLPTYEQGAEVATRRAYGDALKA
LGAAQPDVVALDAEVSNSTYTEDFAEAYPERYFEMYIAEQQMVAAAVGLQVRQYKPFASTFAAFLSRAYDFVRMAAVSRA
NIKLVGSHAGVSIGQDGPSQMALEDLAAFRAVWNSTVLYPCDANQTAKLVEQMSDLQGIVYLRTTRENTPVIYGTEEDFP
IGGSKVIRSSDQDQATIIGAGITLHEAIKAGDHLKNEGIIVRIIDAYSVKPIDVKTLHQAANDTEGNLVVVEDHWHEGGL
GAAVLDAFAGVGNLSSYDGPPLQLIKLAVHNMPGSGTPEELLHAAKIDADAIVEAVKLQVRHPIGARISIHP

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=620, Percent_Identity=48.0645161290323, Blast_Score=594, Evalue=1e-170,
Organism=Homo sapiens, GI4507521, Length=620, Percent_Identity=48.0645161290323, Blast_Score=594, Evalue=1e-170,
Organism=Homo sapiens, GI133778974, Length=621, Percent_Identity=45.4106280193237, Blast_Score=520, Evalue=1e-147,
Organism=Homo sapiens, GI225637459, Length=621, Percent_Identity=40.9017713365539, Blast_Score=464, Evalue=1e-130,
Organism=Homo sapiens, GI225637461, Length=621, Percent_Identity=40.4186795491143, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI225637463, Length=585, Percent_Identity=40.5128205128205, Blast_Score=433, Evalue=1e-121,
Organism=Escherichia coli, GI1788808, Length=590, Percent_Identity=29.3220338983051, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI48994911, Length=586, Percent_Identity=27.8156996587031, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786622, Length=650, Percent_Identity=24.4615384615385, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17539652, Length=624, Percent_Identity=45.9935897435897, Blast_Score=555, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6325331, Length=579, Percent_Identity=29.8791018998273, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6319593, Length=584, Percent_Identity=27.0547945205479, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI45551847, Length=623, Percent_Identity=44.7833065810594, Blast_Score=537, Evalue=1e-152,
Organism=Drosophila melanogaster, GI45550715, Length=623, Percent_Identity=44.7833065810594, Blast_Score=537, Evalue=1e-152,
Organism=Drosophila melanogaster, GI24645119, Length=585, Percent_Identity=44.6153846153846, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24666278, Length=625, Percent_Identity=40.8, Blast_Score=489, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 68458; Mature: 68327

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQEQLHQWHELAQQLRIDSIRATTGATSGHPTSSMSPADLMAVLLTNYLHYDFDNPHH
CCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PNNDRFILSKGHAAPLLYAMYKAAGVITDEELMSLRQMGSRLEGHPTPVLPWVDVATGSL
CCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCC
GQGLPIGVGLGLAGKYLDQLPYNVWVLLGDSETAEGSVWEAFDHAAHYTLDNLIAIIDVN
CCCCCEEECCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEHH
RLGQRGQTELGWNTQAYANRAKAFGWQAIEIDGHDLTEIDQAFSAAVSINDRPTVIIART
HCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHEEEECCCCEEEEEEC
KKGKGVASLEDLGGWHGKALKPDAAKQAIAELGGERQITIQVAKPEPEQPALANPQPFQL
CCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCC
PTYEQGAEVATRRAYGDALKALGAAQPDVVALDAEVSNSTYTEDFAEAYPERYFEMYIAE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
QQMVAAAVGLQVRQYKPFASTFAAFLSRAYDFVRMAAVSRANIKLVGSHAGVSIGQDGPS
HHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHH
QMALEDLAAFRAVWNSTVLYPCDANQTAKLVEQMSDLQGIVYLRTTRENTPVIYGTEEDF
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCC
PIGGSKVIRSSDQDQATIIGAGITLHEAIKAGDHLKNEGIIVRIIDAYSVKPIDVKTLHQ
CCCCHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHH
AANDTEGNLVVVEDHWHEGGLGAAVLDAFAGVGNLSSYDGPPLQLIKLAVHNMPGSGTPE
HCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
ELLHAAKIDADAIVEAVKLQVRHPIGARISIHP
HHHHHHHCCHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
TIQEQLHQWHELAQQLRIDSIRATTGATSGHPTSSMSPADLMAVLLTNYLHYDFDNPHH
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PNNDRFILSKGHAAPLLYAMYKAAGVITDEELMSLRQMGSRLEGHPTPVLPWVDVATGSL
CCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCC
GQGLPIGVGLGLAGKYLDQLPYNVWVLLGDSETAEGSVWEAFDHAAHYTLDNLIAIIDVN
CCCCCEEECCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEHH
RLGQRGQTELGWNTQAYANRAKAFGWQAIEIDGHDLTEIDQAFSAAVSINDRPTVIIART
HCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHEEEECCCCEEEEEEC
KKGKGVASLEDLGGWHGKALKPDAAKQAIAELGGERQITIQVAKPEPEQPALANPQPFQL
CCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCC
PTYEQGAEVATRRAYGDALKALGAAQPDVVALDAEVSNSTYTEDFAEAYPERYFEMYIAE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
QQMVAAAVGLQVRQYKPFASTFAAFLSRAYDFVRMAAVSRANIKLVGSHAGVSIGQDGPS
HHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHH
QMALEDLAAFRAVWNSTVLYPCDANQTAKLVEQMSDLQGIVYLRTTRENTPVIYGTEEDF
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCC
PIGGSKVIRSSDQDQATIIGAGITLHEAIKAGDHLKNEGIIVRIIDAYSVKPIDVKTLHQ
CCCCHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHH
AANDTEGNLVVVEDHWHEGGLGAAVLDAFAGVGNLSSYDGPPLQLIKLAVHNMPGSGTPE
HCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
ELLHAAKIDADAIVEAVKLQVRHPIGARISIHP
HHHHHHHCCHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]