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The map label for this gene is btuC [H]

Identifier: 17231524

GI number: 17231524

Start: 4857483

End: 4858571

Strand: Direct

Name: btuC [H]

Synonym: alr4032

Alternate gene names: 17231524

Gene position: 4857483-4858571 (Clockwise)

Preceding gene: 17231523

Following gene: 17231525

Centisome position: 75.74

GC content: 36.55

Gene sequence:

>1089_bases
ATGTTAAGTGAAAAATATAAATTTAAAAACTCTTTATTAACCCACAATTCTCAAATTATAAAAAGCCTTATTTTCTCAGT
TTTATTAATAGGTTTACTATGTGCCTTTTTATTAGACTTAGCTTTAGGCTCAGTTGATATCCCTATCAACGAAGTAGTCA
ATATTTTACTCGGACAAGAACCAGAAAAAGCAACTCATGCTCATATTATTCTCAAATTTCGCTTACCTAAAGCTTTAACT
GCAACTTTAGCAGGTGCAGCTTTAGGTGTGAGTGGCTTACAAATGCAAACCTTATTTAAAAATCCCTTAGCGGGGCCTTT
TGTATTGGGAATTAGTTCTGGTGCAAGTTTAGGTGTGGCGTTAGTTGTGCTGACAGCAAGTGTAACAACACCAACATTAT
TAACAGATTTGGGAATCATTAGTGATTTTGGTTTAGTTATAGCAGCAAGTCTCGGCGCAGCATCAGTTTTAGGGATGATG
TTAGTTGTGTCTCGCCGAGTGCAAGACACAATGACGCTACTGATTTTAGGTTTATTGTTTGGTTATGCTACTAGTGCAAT
TGTGAGTATTTTGTTGCAGTTTAGCTCAAAGGAACGCATTCAAAATTATATTATGTGGACTTTTGGGAGTTTTGCTGGGG
TGACTTGGAAACAGTTAATTGTTTTAATTCCAGTGATAGTTTTAAGTTTATTAGTGGCGGTGTTGCAATCGAAGTCTTTA
AATGCGCTGTTATTGGGAGAAACTTACGCACGTAGTTTAGGCTTAACAGTACAGAAAACTAGATTTTCAATTATTACTAG
TGCGTCTATATTAGCAGGGGCAATTACGGCTTTTTGTGGCCCTATAGCATTTCTAGGTGTGGCTATTCCCCATCTGTGCC
GTAGTTTATTTAATACTTCCGACCATAGAATGTTAATCCCTAGTGTAATAATTATGGGTGCAATCTTAGCATTAATTGCT
GATTTGTTTTCTCAACTTTGGGTAAGTCAGATGGTTTTACCTTTGAATGCAATTACTGCTTTAATTGGTACTCCTGTTGT
AACTTGGGTAATTCTGCGGCGTAATTCCCAAAAATCTTTCCCGTCATGA

Upstream 100 bases:

>100_bases
TTAGTAACCCAGATATAGTTTTATCTGACTTAATTAGAATACTGCATCCAGAGATATTACCGAATCATCAATTATTTTAT
TACCACAAAATTCTTAAATA

Downstream 100 bases:

>100_bases
GTAATCCAATTTTAACAACTCACAATCTGACTATTGGTTATAAAACATCCAGAAAAAATGTTCGGTGTGTTGCATCAGAT
ATTTCGGTATCTCTGCAATC

Product: permease protein of iron(III) ABC transporter

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLSEKYKFKNSLLTHNSQIIKSLIFSVLLIGLLCAFLLDLALGSVDIPINEVVNILLGQEPEKATHAHIILKFRLPKALT
ATLAGAALGVSGLQMQTLFKNPLAGPFVLGISSGASLGVALVVLTASVTTPTLLTDLGIISDFGLVIAASLGAASVLGMM
LVVSRRVQDTMTLLILGLLFGYATSAIVSILLQFSSKERIQNYIMWTFGSFAGVTWKQLIVLIPVIVLSLLVAVLQSKSL
NALLLGETYARSLGLTVQKTRFSIITSASILAGAITAFCGPIAFLGVAIPHLCRSLFNTSDHRMLIPSVIIMGAILALIA
DLFSQLWVSQMVLPLNAITALIGTPVVTWVILRRNSQKSFPS

Sequences:

>Translated_362_residues
MLSEKYKFKNSLLTHNSQIIKSLIFSVLLIGLLCAFLLDLALGSVDIPINEVVNILLGQEPEKATHAHIILKFRLPKALT
ATLAGAALGVSGLQMQTLFKNPLAGPFVLGISSGASLGVALVVLTASVTTPTLLTDLGIISDFGLVIAASLGAASVLGMM
LVVSRRVQDTMTLLILGLLFGYATSAIVSILLQFSSKERIQNYIMWTFGSFAGVTWKQLIVLIPVIVLSLLVAVLQSKSL
NALLLGETYARSLGLTVQKTRFSIITSASILAGAITAFCGPIAFLGVAIPHLCRSLFNTSDHRMLIPSVIIMGAILALIA
DLFSQLWVSQMVLPLNAITALIGTPVVTWVILRRNSQKSFPS
>Mature_362_residues
MLSEKYKFKNSLLTHNSQIIKSLIFSVLLIGLLCAFLLDLALGSVDIPINEVVNILLGQEPEKATHAHIILKFRLPKALT
ATLAGAALGVSGLQMQTLFKNPLAGPFVLGISSGASLGVALVVLTASVTTPTLLTDLGIISDFGLVIAASLGAASVLGMM
LVVSRRVQDTMTLLILGLLFGYATSAIVSILLQFSSKERIQNYIMWTFGSFAGVTWKQLIVLIPVIVLSLLVAVLQSKSL
NALLLGETYARSLGLTVQKTRFSIITSASILAGAITAFCGPIAFLGVAIPHLCRSLFNTSDHRMLIPSVIIMGAILALIA
DLFSQLWVSQMVLPLNAITALIGTPVVTWVILRRNSQKSFPS

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=35.5400696864112, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1790740, Length=320, Percent_Identity=31.25, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790741, Length=290, Percent_Identity=32.4137931034483, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786804, Length=284, Percent_Identity=31.6901408450704, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786347, Length=321, Percent_Identity=29.595015576324, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786805, Length=321, Percent_Identity=30.5295950155763, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38579; Mature: 38579

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEKYKFKNSLLTHNSQIIKSLIFSVLLIGLLCAFLLDLALGSVDIPINEVVNILLGQE
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PEKATHAHIILKFRLPKALTATLAGAALGVSGLQMQTLFKNPLAGPFVLGISSGASLGVA
CCCCCCEEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHH
LVVLTASVTTPTLLTDLGIISDFGLVIAASLGAASVLGMMLVVSRRVQDTMTLLILGLLF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYATSAIVSILLQFSSKERIQNYIMWTFGSFAGVTWKQLIVLIPVIVLSLLVAVLQSKSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NALLLGETYARSLGLTVQKTRFSIITSASILAGAITAFCGPIAFLGVAIPHLCRSLFNTS
CEEEECHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHRMLIPSVIIMGAILALIADLFSQLWVSQMVLPLNAITALIGTPVVTWVILRRNSQKSF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PS
CC
>Mature Secondary Structure
MLSEKYKFKNSLLTHNSQIIKSLIFSVLLIGLLCAFLLDLALGSVDIPINEVVNILLGQE
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PEKATHAHIILKFRLPKALTATLAGAALGVSGLQMQTLFKNPLAGPFVLGISSGASLGVA
CCCCCCEEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHH
LVVLTASVTTPTLLTDLGIISDFGLVIAASLGAASVLGMMLVVSRRVQDTMTLLILGLLF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYATSAIVSILLQFSSKERIQNYIMWTFGSFAGVTWKQLIVLIPVIVLSLLVAVLQSKSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NALLLGETYARSLGLTVQKTRFSIITSASILAGAITAFCGPIAFLGVAIPHLCRSLFNTS
CEEEECHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHRMLIPSVIIMGAILALIADLFSQLWVSQMVLPLNAITALIGTPVVTWVILRRNSQKSF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA