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The map label for this gene is fbp [H]

Identifier: 17231513

GI number: 17231513

Start: 4842083

End: 4843132

Strand: Reverse

Name: fbp [H]

Synonym: all4021

Alternate gene names: 17231513

Gene position: 4843132-4842083 (Counterclockwise)

Preceding gene: 17231514

Following gene: 17231512

Centisome position: 75.51

GC content: 44.0

Gene sequence:

>1050_bases
ATGGCTAAAGCCTCAGAATCCTTGGATTTGTCTGTCAACGAGTCTACAGATAAAGCTCTAGACCGCGATTGTACAACCTT
ATCCCGTCACGTCCTCCAACAACTCCAAAGTTTTTCCGCAGATGCACAAGATTTGAGTGCATTAATGAATCGGATTGCTT
TAGCAGGTAAATTAGTTGCCCGTCGCCTTAGCCGCGCTGGTTTAATGGAAGGGGTTCTCGGATTTACTGGGGAGGTAAAT
GTACAAGGTGAATCCGTCAAAAAGATGGATGTCTATGCCAATGACGTGTTTATCTCAGTGTTTAAGCAAAGCGGCTTAGT
TTGTCGTCTTGCATCTGAGGAAATGGATGAACCATATTACATTCCCGAAAATTGCCCCATAGGTCGTTACACCTTACTGT
ATGACCCAATAGACGGTTCCTCAAACACAGATACAAATCTCAGTTTGGGTTCCATTTTCTCTATCCGTCAACAGGAAGGT
GATGATAGTGATGGCCAAGCTAAAGACCTCCTCACCAACGGACGCAAGCAGATTGCGGCGGGTTACATTTTATATGGGCC
TAGCACGATGCTAGTTTATACAATGGGTACGGGAGTTCACTCATTTACCCTTGATCCCAGCTTAGGAGAATTCATCCTCA
GCGAAGAAAATATCCGCATTCCCGACCACGGCGCAGTTTACAGCGTTAATGAAGGTAACTTCTGGCAATGGGAAGAATCA
ATGCGGGAATATATCCGCTATGTTCACCGTACAGAAGGTTACACAGCTCGTTACAGTGGTGCAATGGTGAGCGATATCCA
TAGAATTTTGGTACAAGGTGGTGTGTTTCTCTACCCAGGGACGATTCAAAACCCTGAAGGTAAATTACGGTTGTTGTATG
AATCTGCTCCTTTAGCCTTTTTAATTCAACAAGCTGGTGGTCGGGCAACTACGGGATTAGTAGATATCTTAGATGTTGTA
CCGAAAAAACTACACCAACGTACACCTCTGATTATTGGTAGTAAAGAGGACGTAGCCAAGGTTGAATCATTTATTCAGAA
TGGTCATTAA

Upstream 100 bases:

>100_bases
CATCTAGGTTATCAAATTACCTTTCTAAGATAGAGGCAGCAACTATGTGTTGCCACGCAAACTTGATCCAACTAACAGCA
GTCGCTAGGAAGTACATAAC

Downstream 100 bases:

>100_bases
CAGGCAGGAGGCAGGGGGAGAATAAGAAATAATAATTCCTAACGCCCTACTCAGCACTTACTACTCAGCACTTTCTCAGC
TAAATGTGAGAGATTATCTC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MAKASESLDLSVNESTDKALDRDCTTLSRHVLQQLQSFSADAQDLSALMNRIALAGKLVARRLSRAGLMEGVLGFTGEVN
VQGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDEPYYIPENCPIGRYTLLYDPIDGSSNTDTNLSLGSIFSIRQQEG
DDSDGQAKDLLTNGRKQIAAGYILYGPSTMLVYTMGTGVHSFTLDPSLGEFILSEENIRIPDHGAVYSVNEGNFWQWEES
MREYIRYVHRTEGYTARYSGAMVSDIHRILVQGGVFLYPGTIQNPEGKLRLLYESAPLAFLIQQAGGRATTGLVDILDVV
PKKLHQRTPLIIGSKEDVAKVESFIQNGH

Sequences:

>Translated_349_residues
MAKASESLDLSVNESTDKALDRDCTTLSRHVLQQLQSFSADAQDLSALMNRIALAGKLVARRLSRAGLMEGVLGFTGEVN
VQGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDEPYYIPENCPIGRYTLLYDPIDGSSNTDTNLSLGSIFSIRQQEG
DDSDGQAKDLLTNGRKQIAAGYILYGPSTMLVYTMGTGVHSFTLDPSLGEFILSEENIRIPDHGAVYSVNEGNFWQWEES
MREYIRYVHRTEGYTARYSGAMVSDIHRILVQGGVFLYPGTIQNPEGKLRLLYESAPLAFLIQQAGGRATTGLVDILDVV
PKKLHQRTPLIIGSKEDVAKVESFIQNGH
>Mature_348_residues
AKASESLDLSVNESTDKALDRDCTTLSRHVLQQLQSFSADAQDLSALMNRIALAGKLVARRLSRAGLMEGVLGFTGEVNV
QGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDEPYYIPENCPIGRYTLLYDPIDGSSNTDTNLSLGSIFSIRQQEGD
DSDGQAKDLLTNGRKQIAAGYILYGPSTMLVYTMGTGVHSFTLDPSLGEFILSEENIRIPDHGAVYSVNEGNFWQWEESM
REYIRYVHRTEGYTARYSGAMVSDIHRILVQGGVFLYPGTIQNPEGKLRLLYESAPLAFLIQQAGGRATTGLVDILDVVP
KKLHQRTPLIIGSKEDVAKVESFIQNGH

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=323, Percent_Identity=42.7244582043344, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI16579888, Length=323, Percent_Identity=42.7244582043344, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI22907028, Length=339, Percent_Identity=41.5929203539823, Blast_Score=254, Evalue=1e-67,
Organism=Escherichia coli, GI1790679, Length=327, Percent_Identity=44.6483180428135, Blast_Score=296, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17508131, Length=337, Percent_Identity=44.213649851632, Blast_Score=290, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6323409, Length=330, Percent_Identity=40.6060606060606, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI45550998, Length=331, Percent_Identity=44.1087613293051, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI19921562, Length=331, Percent_Identity=44.1087613293051, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 38519; Mature: 38388

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKASESLDLSVNESTDKALDRDCTTLSRHVLQQLQSFSADAQDLSALMNRIALAGKLVA
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RRLSRAGLMEGVLGFTGEVNVQGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDEPYY
HHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHEEHHHCCCEEEECCCCCCCCEE
IPENCPIGRYTLLYDPIDGSSNTDTNLSLGSIFSIRQQEGDDSDGQAKDLLTNGRKQIAA
CCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHC
GYILYGPSTMLVYTMGTGVHSFTLDPSLGEFILSEENIRIPDHGAVYSVNEGNFWQWEES
CEEEECCCEEEEEEECCCCEEEEECCCHHHHHCCCCCEECCCCCCEEEECCCCCCHHHHH
MREYIRYVHRTEGYTARYSGAMVSDIHRILVQGGVFLYPGTIQNPEGKLRLLYESAPLAF
HHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHH
LIQQAGGRATTGLVDILDVVPKKLHQRTPLIIGSKEDVAKVESFIQNGH
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKASESLDLSVNESTDKALDRDCTTLSRHVLQQLQSFSADAQDLSALMNRIALAGKLVA
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RRLSRAGLMEGVLGFTGEVNVQGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDEPYY
HHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHEEHHHCCCEEEECCCCCCCCEE
IPENCPIGRYTLLYDPIDGSSNTDTNLSLGSIFSIRQQEGDDSDGQAKDLLTNGRKQIAA
CCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHC
GYILYGPSTMLVYTMGTGVHSFTLDPSLGEFILSEENIRIPDHGAVYSVNEGNFWQWEES
CEEEECCCEEEEEEECCCCEEEEECCCHHHHHCCCCCEECCCCCCEEEECCCCCCHHHHH
MREYIRYVHRTEGYTARYSGAMVSDIHRILVQGGVFLYPGTIQNPEGKLRLLYESAPLAF
HHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHH
LIQQAGGRATTGLVDILDVVPKKLHQRTPLIIGSKEDVAKVESFIQNGH
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA