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The map label for this gene is resE [H]

Identifier: 17231474

GI number: 17231474

Start: 4795771

End: 4797135

Strand: Direct

Name: resE [H]

Synonym: alr3982

Alternate gene names: 17231474

Gene position: 4795771-4797135 (Clockwise)

Preceding gene: 17231472

Following gene: 17231480

Centisome position: 74.77

GC content: 42.93

Gene sequence:

>1365_bases
ATGTTAATGTCTGCCAGTTCAGATTTTGTGGCTCTATGTCGAGAGCAAATAGCACTACTTACCCAAGGGCTAGGAGCTTC
TTTAAGTGTAGTTTATCTAACCCAAGAATTGATAGAGTCGCCAACGGGGGAGGCGAAACTGATTCCTGTGGTTGTTTACC
CAGAGACGGCAGTTATACTACCAGGAGAAGAGCTTGCTGAGGTGAATGCACGTAAACAATTACAAGTGGGTGAGGTACTG
TTGCTACCTCAAAAACAGGGAAAGTTATTGACTGTAGCGCCAGCCGAAGAAACACCAGAGTCGGGGAGAGCGCCTACAGT
AGGTGGAACGTCATCGCCTTTTGGTGATGATTACTTGTTAGATGAACGCCAAATAGTCTTACCTCTGGTGCATGAGGGCG
TAATGATGGGATTATTGGTAACAAGCAGAGCCGATCGCCCCTGGAACGAACAAGAGCAAAGTCAAGTGGAGAAAGTCGGA
CAAACATTGGCGATCGCTTGTATTTTGGATCAGCGTCGAGCATGGTTGCAACACCAACTGCATCAACAACAAATTCTGCA
AGAACAACAGCAAGATTTACTTGATAATTTATTGCATCAGTTTCGTAATCCCTTAACTGCCTTACGGACTTTTGGTAAAC
TTCTCTTGAAAAGATTGCGCCCTGGTGATCCAAATCGAGATGTGGGCGAGAATATTGTCAGGGAGAGCGATCGCCTCAAG
GAATTGCTACAAAAGTTTGAGCAAGTTATTGATTGGACAGAGGCAGATTTATCTAGGCTAGTGTTACCAGAAAAAGAGGG
ATTTGTCGAAGCCACTGTCCAAAAAGAAGCCAAACCAGCGCTATTATTACCGGGGACGGGAGAGCAATTAACTGATTGTG
CTGTAGTTGATTTATTAACACCATTACTCATGTCAGCCAAAGCGATCGCCCAAGACAGACATATCAAGTTAAAAGCAGAT
ATTTCTCAAGATTTGCCATTAGTCAGGGTAAATATTAAAGCTTTGCAAGAAGTGTTGAGTAATATCATTGATAATGCTTT
AAAATACACACCCCAAGGTGGCAAGATTTATATTCAAGCCGGGCAAGAAAAACTGAACTTCCAAGGCATTGCGATTAGTG
ATAATGGCCCTGGTATTCCTCAAGAAGATTTAGTCCATTTAGGTGAAAGACATTACCGAGGCGTACAAGCCCAAACAGAA
ATTCCTGGCACAGGCTTAGGATTAGCGATCGCTAAACAATTAATTGAGCAAATGCAGGGCGAAATTGAAATTTTCAGCCC
GGCAATTAACTCTAAATTAACCTCACCCAATACACCAGGAACGACGTTTATTATTTGGTTACCGATGAGTCAAAGTAATT
CGTAA

Upstream 100 bases:

>100_bases
ACTCGAAAGATTTAGTTAAGCTTTATTAAATAACTGAGGAAAATAAAGTATCTTCTCTTATCTTCCCTCAAAAACCGTGA
TCCTGAGCAAGAGCTGAAAA

Downstream 100 bases:

>100_bases
TTAATAAATTAGTGTTGTTATTAATTGGGAATTACCAGCAGGGGTTGACTATCTTAATGAAACCAGTAGATTTTGGTTAA
TGGTCATTTGTAAATCGGTG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MLMSASSDFVALCREQIALLTQGLGASLSVVYLTQELIESPTGEAKLIPVVVYPETAVILPGEELAEVNARKQLQVGEVL
LLPQKQGKLLTVAPAEETPESGRAPTVGGTSSPFGDDYLLDERQIVLPLVHEGVMMGLLVTSRADRPWNEQEQSQVEKVG
QTLAIACILDQRRAWLQHQLHQQQILQEQQQDLLDNLLHQFRNPLTALRTFGKLLLKRLRPGDPNRDVGENIVRESDRLK
ELLQKFEQVIDWTEADLSRLVLPEKEGFVEATVQKEAKPALLLPGTGEQLTDCAVVDLLTPLLMSAKAIAQDRHIKLKAD
ISQDLPLVRVNIKALQEVLSNIIDNALKYTPQGGKIYIQAGQEKLNFQGIAISDNGPGIPQEDLVHLGERHYRGVQAQTE
IPGTGLGLAIAKQLIEQMQGEIEIFSPAINSKLTSPNTPGTTFIIWLPMSQSNS

Sequences:

>Translated_454_residues
MLMSASSDFVALCREQIALLTQGLGASLSVVYLTQELIESPTGEAKLIPVVVYPETAVILPGEELAEVNARKQLQVGEVL
LLPQKQGKLLTVAPAEETPESGRAPTVGGTSSPFGDDYLLDERQIVLPLVHEGVMMGLLVTSRADRPWNEQEQSQVEKVG
QTLAIACILDQRRAWLQHQLHQQQILQEQQQDLLDNLLHQFRNPLTALRTFGKLLLKRLRPGDPNRDVGENIVRESDRLK
ELLQKFEQVIDWTEADLSRLVLPEKEGFVEATVQKEAKPALLLPGTGEQLTDCAVVDLLTPLLMSAKAIAQDRHIKLKAD
ISQDLPLVRVNIKALQEVLSNIIDNALKYTPQGGKIYIQAGQEKLNFQGIAISDNGPGIPQEDLVHLGERHYRGVQAQTE
IPGTGLGLAIAKQLIEQMQGEIEIFSPAINSKLTSPNTPGTTFIIWLPMSQSNS
>Mature_454_residues
MLMSASSDFVALCREQIALLTQGLGASLSVVYLTQELIESPTGEAKLIPVVVYPETAVILPGEELAEVNARKQLQVGEVL
LLPQKQGKLLTVAPAEETPESGRAPTVGGTSSPFGDDYLLDERQIVLPLVHEGVMMGLLVTSRADRPWNEQEQSQVEKVG
QTLAIACILDQRRAWLQHQLHQQQILQEQQQDLLDNLLHQFRNPLTALRTFGKLLLKRLRPGDPNRDVGENIVRESDRLK
ELLQKFEQVIDWTEADLSRLVLPEKEGFVEATVQKEAKPALLLPGTGEQLTDCAVVDLLTPLLMSAKAIAQDRHIKLKAD
ISQDLPLVRVNIKALQEVLSNIIDNALKYTPQGGKIYIQAGQEKLNFQGIAISDNGPGIPQEDLVHLGERHYRGVQAQTE
IPGTGLGLAIAKQLIEQMQGEIEIFSPAINSKLTSPNTPGTTFIIWLPMSQSNS

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=288, Percent_Identity=23.2638888888889, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788713, Length=155, Percent_Identity=37.4193548387097, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=37.8640776699029, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=261, Percent_Identity=27.2030651340996, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=276, Percent_Identity=25.7246376811594, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=133, Percent_Identity=32.3308270676692, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787374, Length=131, Percent_Identity=32.824427480916, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50032; Mature: 50032

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMSASSDFVALCREQIALLTQGLGASLSVVYLTQELIESPTGEAKLIPVVVYPETAVIL
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEE
PGEELAEVNARKQLQVGEVLLLPQKQGKLLTVAPAEETPESGRAPTVGGTSSPFGDDYLL
CCHHHHHCCHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEE
DERQIVLPLVHEGVMMGLLVTSRADRPWNEQEQSQVEKVGQTLAIACILDQRRAWLQHQL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQQQILQEQQQDLLDNLLHQFRNPLTALRTFGKLLLKRLRPGDPNRDVGENIVRESDRLK
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ELLQKFEQVIDWTEADLSRLVLPEKEGFVEATVQKEAKPALLLPGTGEQLTDCAVVDLLT
HHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHH
PLLMSAKAIAQDRHIKLKADISQDLPLVRVNIKALQEVLSNIIDNALKYTPQGGKIYIQA
HHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GQEKLNFQGIAISDNGPGIPQEDLVHLGERHYRGVQAQTEIPGTGLGLAIAKQLIEQMQG
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
EIEIFSPAINSKLTSPNTPGTTFIIWLPMSQSNS
CEEEECHHHCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MLMSASSDFVALCREQIALLTQGLGASLSVVYLTQELIESPTGEAKLIPVVVYPETAVIL
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEE
PGEELAEVNARKQLQVGEVLLLPQKQGKLLTVAPAEETPESGRAPTVGGTSSPFGDDYLL
CCHHHHHCCHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEE
DERQIVLPLVHEGVMMGLLVTSRADRPWNEQEQSQVEKVGQTLAIACILDQRRAWLQHQL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQQQILQEQQQDLLDNLLHQFRNPLTALRTFGKLLLKRLRPGDPNRDVGENIVRESDRLK
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ELLQKFEQVIDWTEADLSRLVLPEKEGFVEATVQKEAKPALLLPGTGEQLTDCAVVDLLT
HHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHH
PLLMSAKAIAQDRHIKLKADISQDLPLVRVNIKALQEVLSNIIDNALKYTPQGGKIYIQA
HHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GQEKLNFQGIAISDNGPGIPQEDLVHLGERHYRGVQAQTEIPGTGLGLAIAKQLIEQMQG
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
EIEIFSPAINSKLTSPNTPGTTFIIWLPMSQSNS
CEEEECHHHCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]