Click here to switch to the map view.

The map label for this gene is glmM [H]

Identifier: 17231456

GI number: 17231456

Start: 4782290

End: 4783717

Strand: Reverse

Name: glmM [H]

Synonym: all3964

Alternate gene names: 17231456

Gene position: 4783717-4782290 (Counterclockwise)

Preceding gene: 17231458

Following gene: 17231455

Centisome position: 74.59

GC content: 45.52

Gene sequence:

>1428_bases
ATGAGCGCTAGTAGCAATTCCAGCAAGATAAAATTTGGTACTGATGGATGGAGAGGCATTATTGCCGATGATTTCACTTT
TCCCAATGTGCGAAAAGTGACAAGAGCGATCGCCAGCTATCTGGAAACAGCCTACACAAAAGATAGACCAGTTCTAATTG
CCTACGATACTCGTTTTTTAGCTGATCAGTTTGCCCAGACAGCAGCTCAAGTCTTGGCTGACTTGGGCTGGAATGTCAAA
GTCACTGATCGGGATTGCCCCACACCAGTAATTGCTTACAATGCCCGTCACCTGAATTCGGCAGGGGCATTGATGTTTAC
GGCTAGCCATAATCCAGCACCCTATTGTGGAATTAAATATATCCCTGATTATGCTGGGCCTGCCACTCCAGAAATTACTG
ATACTATTGTGGCAAATATTGAAAGTGCTTCAGATGAATTGCCAAGTGGCAAACCATCGGGAACAATTTCTACTTTTGAT
CCCAAACCGGACTATTTACAGTTTATTTACACATTGCTGGATATAGAACGAATTAAAAGCGCTCAACTTAAAGTCAAGTA
TGATGCGTTATATTCTACATCCCGTGGCTATTTAGATGAAGTATTGCTAGAGAGTGGGGTGCAATTAGAAAGTTTCCACA
CTTGGCGCGATGTCCTCTTTGGTGGGGGAATGCCTGAACCAAAGGGAGAACAGCTAGTGGAATTAGTCGAAGCTGTCCGC
CGCGATCATGCAGATTTAGGACTAGCGACAGATGGCGACAGCGATCGCTTTGGGATTGTGGATGAGCTAGGCAACGTCCT
CACTCCTAACACTGTGTTGTTAGTTCTAGCGCGGCATTTAATCAAGAATAAAGGCAAAACAGGCGCGATCGTCCGCACTG
TGGCTACAACTCACCTACTCGATAATTTCGCCGCTAAATACGGCTTGACGATTTATGAGACAGCCGTAGGTTTTAAATAC
ATTGGGGAAAAAATGCGGGAAACCGCCGTGCTGATTGGTGGTGAAGAATCAGGCGGTTTAAGCATTATTGGGCATATTCC
CGAAAAAGACGGCGTTTTAGCTGATATGCTGATTGCCGAAGCGATCGCCTATGAAGGTAAGCCCCTGAGTCAATTGGTGA
AGGAAGCGATCGCCGAAGCTGATGGCCCCTTATATAACAACCGTCTTGACTTACACTTAACAGAAGCTCATAAAGTCGCC
GTCATCGACTCCTTTACAAAAAATCCTCCTTCCGAGGTAGCTGGAATTAAAGTGAAGGAAGTCGGACGTAAGGACGGAAT
TAAGCTGTATTTAGAAGAAGGTAGCTGGGTGTTGCTGCGTCCCTCTGGTACTGAGCCTTTGGTGCGTGTTTACCTAGAAA
CCAACTCTCCCGAAAAACTCAGCAAACTAGAGCAAGAGTTAGAGAGTGCGATCGCTAAGTTAGGATAA

Upstream 100 bases:

>100_bases
AAGAGCAGTGAGAAAAAATACGGTGAAGGATGCTTGCGACTACGCACGCTTTGCGGGAAGCTTCCTATAGTGTTCAAATA
GATGGGGGACAGTAGCAAAC

Downstream 100 bases:

>100_bases
GAATCTCAACCGCAGATGAACACAGGCGTTCATCTGCGTGTATTTGTGGTTCGTGATTTTATGAAAACTTTGGCACCTTT
TTTCACATCTTTAGTTGTAG

Product: phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSASSNSSKIKFGTDGWRGIIADDFTFPNVRKVTRAIASYLETAYTKDRPVLIAYDTRFLADQFAQTAAQVLADLGWNVK
VTDRDCPTPVIAYNARHLNSAGALMFTASHNPAPYCGIKYIPDYAGPATPEITDTIVANIESASDELPSGKPSGTISTFD
PKPDYLQFIYTLLDIERIKSAQLKVKYDALYSTSRGYLDEVLLESGVQLESFHTWRDVLFGGGMPEPKGEQLVELVEAVR
RDHADLGLATDGDSDRFGIVDELGNVLTPNTVLLVLARHLIKNKGKTGAIVRTVATTHLLDNFAAKYGLTIYETAVGFKY
IGEKMRETAVLIGGEESGGLSIIGHIPEKDGVLADMLIAEAIAYEGKPLSQLVKEAIAEADGPLYNNRLDLHLTEAHKVA
VIDSFTKNPPSEVAGIKVKEVGRKDGIKLYLEEGSWVLLRPSGTEPLVRVYLETNSPEKLSKLEQELESAIAKLG

Sequences:

>Translated_475_residues
MSASSNSSKIKFGTDGWRGIIADDFTFPNVRKVTRAIASYLETAYTKDRPVLIAYDTRFLADQFAQTAAQVLADLGWNVK
VTDRDCPTPVIAYNARHLNSAGALMFTASHNPAPYCGIKYIPDYAGPATPEITDTIVANIESASDELPSGKPSGTISTFD
PKPDYLQFIYTLLDIERIKSAQLKVKYDALYSTSRGYLDEVLLESGVQLESFHTWRDVLFGGGMPEPKGEQLVELVEAVR
RDHADLGLATDGDSDRFGIVDELGNVLTPNTVLLVLARHLIKNKGKTGAIVRTVATTHLLDNFAAKYGLTIYETAVGFKY
IGEKMRETAVLIGGEESGGLSIIGHIPEKDGVLADMLIAEAIAYEGKPLSQLVKEAIAEADGPLYNNRLDLHLTEAHKVA
VIDSFTKNPPSEVAGIKVKEVGRKDGIKLYLEEGSWVLLRPSGTEPLVRVYLETNSPEKLSKLEQELESAIAKLG
>Mature_474_residues
SASSNSSKIKFGTDGWRGIIADDFTFPNVRKVTRAIASYLETAYTKDRPVLIAYDTRFLADQFAQTAAQVLADLGWNVKV
TDRDCPTPVIAYNARHLNSAGALMFTASHNPAPYCGIKYIPDYAGPATPEITDTIVANIESASDELPSGKPSGTISTFDP
KPDYLQFIYTLLDIERIKSAQLKVKYDALYSTSRGYLDEVLLESGVQLESFHTWRDVLFGGGMPEPKGEQLVELVEAVRR
DHADLGLATDGDSDRFGIVDELGNVLTPNTVLLVLARHLIKNKGKTGAIVRTVATTHLLDNFAAKYGLTIYETAVGFKYI
GEKMRETAVLIGGEESGGLSIIGHIPEKDGVLADMLIAEAIAYEGKPLSQLVKEAIAEADGPLYNNRLDLHLTEAHKVAV
IDSFTKNPPSEVAGIKVKEVGRKDGIKLYLEEGSWVLLRPSGTEPLVRVYLETNSPEKLSKLEQELESAIAKLG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=516, Percent_Identity=23.8372093023256, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI290463102, Length=507, Percent_Identity=23.8658777120316, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI133922562, Length=518, Percent_Identity=22.7799227799228, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI290463104, Length=340, Percent_Identity=24.7058823529412, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786904, Length=517, Percent_Identity=25.7253384912959, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1789566, Length=475, Percent_Identity=26.3157894736842, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788361, Length=452, Percent_Identity=24.5575221238938, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17535441, Length=486, Percent_Identity=25.3086419753086, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322722, Length=482, Percent_Identity=25.7261410788382, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323752, Length=490, Percent_Identity=25.3061224489796, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17864244, Length=523, Percent_Identity=25.4302103250478, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129809, Length=416, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24651977, Length=416, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24653722, Length=402, Percent_Identity=24.1293532338308, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 51820; Mature: 51689

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSNSSKIKFGTDGWRGIIADDFTFPNVRKVTRAIASYLETAYTKDRPVLIAYDTRFL
CCCCCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
ADQFAQTAAQVLADLGWNVKVTDRDCPTPVIAYNARHLNSAGALMFTASHNPAPYCGIKY
HHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCEE
IPDYAGPATPEITDTIVANIESASDELPSGKPSGTISTFDPKPDYLQFIYTLLDIERIKS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCC
AQLKVKYDALYSTSRGYLDEVLLESGVQLESFHTWRDVLFGGGMPEPKGEQLVELVEAVR
CCEEEEEHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RDHADLGLATDGDSDRFGIVDELGNVLTPNTVLLVLARHLIKNKGKTGAIVRTVATTHLL
HCCCCCCEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DNFAAKYGLTIYETAVGFKYIGEKMRETAVLIGGEESGGLSIIGHIPEKDGVLADMLIAE
HHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHH
AIAYEGKPLSQLVKEAIAEADGPLYNNRLDLHLTEAHKVAVIDSFTKNPPSEVAGIKVKE
HHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHCCCCHHH
VGRKDGIKLYLEEGSWVLLRPSGTEPLVRVYLETNSPEKLSKLEQELESAIAKLG
CCCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASSNSSKIKFGTDGWRGIIADDFTFPNVRKVTRAIASYLETAYTKDRPVLIAYDTRFL
CCCCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
ADQFAQTAAQVLADLGWNVKVTDRDCPTPVIAYNARHLNSAGALMFTASHNPAPYCGIKY
HHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCEE
IPDYAGPATPEITDTIVANIESASDELPSGKPSGTISTFDPKPDYLQFIYTLLDIERIKS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCC
AQLKVKYDALYSTSRGYLDEVLLESGVQLESFHTWRDVLFGGGMPEPKGEQLVELVEAVR
CCEEEEEHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RDHADLGLATDGDSDRFGIVDELGNVLTPNTVLLVLARHLIKNKGKTGAIVRTVATTHLL
HCCCCCCEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DNFAAKYGLTIYETAVGFKYIGEKMRETAVLIGGEESGGLSIIGHIPEKDGVLADMLIAE
HHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHH
AIAYEGKPLSQLVKEAIAEADGPLYNNRLDLHLTEAHKVAVIDSFTKNPPSEVAGIKVKE
HHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHCCCCHHH
VGRKDGIKLYLEEGSWVLLRPSGTEPLVRVYLETNSPEKLSKLEQELESAIAKLG
CCCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]