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The map label for this gene is sucC [H]

Identifier: 17231406

GI number: 17231406

Start: 4718088

End: 4719314

Strand: Reverse

Name: sucC [H]

Synonym: all3914

Alternate gene names: 17231406

Gene position: 4719314-4718088 (Counterclockwise)

Preceding gene: 17231408

Following gene: 17231405

Centisome position: 73.58

GC content: 41.73

Gene sequence:

>1227_bases
ATGGATTTATTGGAGTACCAAGTTAAAGAATGGTTTGGGGAAATAGGCATTCCTGTATTGCCATCCCAAAGAATTGACCA
TCCTACAGATTTAAAACGCTTAAAAATTCGCTACCCAATTGTGCTGAAATCACAGGTTCATGCGGGGGAGAGGGAAAAAG
TCGGTGGTGTGAGAATGGTAGAAACCACAATCGACGCGATCGCCGCAGCTCAAACTATCTTTAATCTATCAATATGGGGC
GAATTACCAGAAGTTTTATTAGCAGAATCTAAGTATAATTCCCACCAGGAATTTTATTTAGCTGTCGTTTTAGATACGGC
TGTTTGTCGTCCGGTACTTTTAGGTTCCACAGAAGCGGATATTGATTTAGAATTAGCTGATCAAAAAATGCAGTATGTGG
TTGTTGAGCAAGAGTTTTCACCTTTTTATGCTCGTAGGTTGGCTTTAAAAATGGGTCTGCAAGGTACACTGATGCAGTCG
GTCAGCACAGTATTAGAAAAAATGTACCAGCTATTCGTGCAGAAAGACCTGGATTTAGTAGAAATAAATCCTCTGGGTGT
CAACCTTGCTGGTGAGGTGATGGCTCTCAATGGTAAAGTTGGAGTCAACGAAAGGGCTATCGGGCGACATCCAGAAATTG
CCGCAATGGCAGCCAAAATAGTCCCTCGCCATTATGATAAAAGTTTTAGTAATGGGCGTGACTGGAATAATTTAGAAAAA
CAACGCAGAATTAGTATTTTAGGTAATGGTACTGGTTCTATTTTGGCGACCTATGATTTAGTTGCTAGTGGCGGCGGTAA
ACCAGGAATTTGCCTAAATCTCCGCCATGCGGCAATTACTGATCTGTCACCAACTAAATTTGGCGATCGCCTCACTAAAG
GTCTAAATACCTTGTCTGCTGACAAAAACACTCAGGTGATCTTGATTAACCTACTAGGAAGTATTCCTCAACCAGAAGAA
GCAGCACAAGCGATCGCTCAATTTATACAACAGAACAAAGGTGAATATCCGCCATCAATTGCCAAGTCTAATGGTAAAAA
CCTTAGTCAACATCAGTCACCACAATTAGTCATTCGTCTAGCCGGTTCAGAGTTGAATGTAGCTAAGGAGGTTTTAGCGG
CTCTACAAACCCGTGAAGAGGGACTGATATTAGTAGAAGATTTAGACGAAGCAGTCGCCACCGCAGTTCGTTTGACTAAA
TCACACGCGTATAAAAAAGTTTCCTGA

Upstream 100 bases:

>100_bases
TAATAGTAGGACAAGACTTGATTATGTGATGAAGGTGCGGTAAAAAATGGAGAATAGCACCAGAGAAATTTTCTAAACGT
ATAAATTAAGGTGCATAGCA

Downstream 100 bases:

>100_bases
GTGGATGAATTATAAGTGCTATAACATGGCGTTGAGCAGCTTCCTGAATGCTGAGTTAAGAAGATATCATTAATTCGTAT
GTTCCCCTCTGCTCCCTGCT

Product: succinyl-CoA synthetase beta chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MDLLEYQVKEWFGEIGIPVLPSQRIDHPTDLKRLKIRYPIVLKSQVHAGEREKVGGVRMVETTIDAIAAAQTIFNLSIWG
ELPEVLLAESKYNSHQEFYLAVVLDTAVCRPVLLGSTEADIDLELADQKMQYVVVEQEFSPFYARRLALKMGLQGTLMQS
VSTVLEKMYQLFVQKDLDLVEINPLGVNLAGEVMALNGKVGVNERAIGRHPEIAAMAAKIVPRHYDKSFSNGRDWNNLEK
QRRISILGNGTGSILATYDLVASGGGKPGICLNLRHAAITDLSPTKFGDRLTKGLNTLSADKNTQVILINLLGSIPQPEE
AAQAIAQFIQQNKGEYPPSIAKSNGKNLSQHQSPQLVIRLAGSELNVAKEVLAALQTREEGLILVEDLDEAVATAVRLTK
SHAYKKVS

Sequences:

>Translated_408_residues
MDLLEYQVKEWFGEIGIPVLPSQRIDHPTDLKRLKIRYPIVLKSQVHAGEREKVGGVRMVETTIDAIAAAQTIFNLSIWG
ELPEVLLAESKYNSHQEFYLAVVLDTAVCRPVLLGSTEADIDLELADQKMQYVVVEQEFSPFYARRLALKMGLQGTLMQS
VSTVLEKMYQLFVQKDLDLVEINPLGVNLAGEVMALNGKVGVNERAIGRHPEIAAMAAKIVPRHYDKSFSNGRDWNNLEK
QRRISILGNGTGSILATYDLVASGGGKPGICLNLRHAAITDLSPTKFGDRLTKGLNTLSADKNTQVILINLLGSIPQPEE
AAQAIAQFIQQNKGEYPPSIAKSNGKNLSQHQSPQLVIRLAGSELNVAKEVLAALQTREEGLILVEDLDEAVATAVRLTK
SHAYKKVS
>Mature_408_residues
MDLLEYQVKEWFGEIGIPVLPSQRIDHPTDLKRLKIRYPIVLKSQVHAGEREKVGGVRMVETTIDAIAAAQTIFNLSIWG
ELPEVLLAESKYNSHQEFYLAVVLDTAVCRPVLLGSTEADIDLELADQKMQYVVVEQEFSPFYARRLALKMGLQGTLMQS
VSTVLEKMYQLFVQKDLDLVEINPLGVNLAGEVMALNGKVGVNERAIGRHPEIAAMAAKIVPRHYDKSFSNGRDWNNLEK
QRRISILGNGTGSILATYDLVASGGGKPGICLNLRHAAITDLSPTKFGDRLTKGLNTLSADKNTQVILINLLGSIPQPEE
AAQAIAQFIQQNKGEYPPSIAKSNGKNLSQHQSPQLVIRLAGSELNVAKEVLAALQTREEGLILVEDLDEAVATAVRLTK
SHAYKKVS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=427, Percent_Identity=25.0585480093677, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI157779135, Length=404, Percent_Identity=25.7425742574257, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI294862256, Length=347, Percent_Identity=27.0893371757925, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1786948, Length=343, Percent_Identity=27.6967930029155, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17567829, Length=380, Percent_Identity=24.4736842105263, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17539378, Length=427, Percent_Identity=23.6533957845433, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6321683, Length=385, Percent_Identity=20, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281361397, Length=387, Percent_Identity=27.1317829457364, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281361395, Length=387, Percent_Identity=27.1317829457364, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI161078106, Length=386, Percent_Identity=26.9430051813472, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24645208, Length=386, Percent_Identity=26.9430051813472, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356231, Length=425, Percent_Identity=25.4117647058824, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 44868; Mature: 44868

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50975 ATP_GRASP ; PS00074 GLFV_DEHYDROGENASE ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLEYQVKEWFGEIGIPVLPSQRIDHPTDLKRLKIRYPIVLKSQVHAGEREKVGGVRMV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEECCEEEECCCCCCCCHHCCCEEEH
ETTIDAIAAAQTIFNLSIWGELPEVLLAESKYNSHQEFYLAVVLDTAVCRPVLLGSTEAD
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHEEEEEEEHHHHHHHHEECCCCCC
IDLELADQKMQYVVVEQEFSPFYARRLALKMGLQGTLMQSVSTVLEKMYQLFVQKDLDLV
EEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
EINPLGVNLAGEVMALNGKVGVNERAIGRHPEIAAMAAKIVPRHYDKSFSNGRDWNNLEK
EECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QRRISILGNGTGSILATYDLVASGGGKPGICLNLRHAAITDLSPTKFGDRLTKGLNTLSA
HHEEEEEECCCCCEEEEEEHHCCCCCCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHCC
DKNTQVILINLLGSIPQPEEAAQAIAQFIQQNKGEYPPSIAKSNGKNLSQHQSPQLVIRL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCEEEEEE
AGSELNVAKEVLAALQTREEGLILVEDLDEAVATAVRLTKSHAYKKVS
CCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLLEYQVKEWFGEIGIPVLPSQRIDHPTDLKRLKIRYPIVLKSQVHAGEREKVGGVRMV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEECCEEEECCCCCCCCHHCCCEEEH
ETTIDAIAAAQTIFNLSIWGELPEVLLAESKYNSHQEFYLAVVLDTAVCRPVLLGSTEAD
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHEEEEEEEHHHHHHHHEECCCCCC
IDLELADQKMQYVVVEQEFSPFYARRLALKMGLQGTLMQSVSTVLEKMYQLFVQKDLDLV
EEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
EINPLGVNLAGEVMALNGKVGVNERAIGRHPEIAAMAAKIVPRHYDKSFSNGRDWNNLEK
EECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QRRISILGNGTGSILATYDLVASGGGKPGICLNLRHAAITDLSPTKFGDRLTKGLNTLSA
HHEEEEEECCCCCEEEEEEHHCCCCCCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHCC
DKNTQVILINLLGSIPQPEEAAQAIAQFIQQNKGEYPPSIAKSNGKNLSQHQSPQLVIRL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCEEEEEE
AGSELNVAKEVLAALQTREEGLILVEDLDEAVATAVRLTKSHAYKKVS
CCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA