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The map label for this gene is mutT [H]

Identifier: 17231391

GI number: 17231391

Start: 4702284

End: 4702730

Strand: Reverse

Name: mutT [H]

Synonym: all3899

Alternate gene names: 17231391

Gene position: 4702730-4702284 (Counterclockwise)

Preceding gene: 17231394

Following gene: 17231390

Centisome position: 73.32

GC content: 46.53

Gene sequence:

>447_bases
TTGTGGCGTATTGGACAAACGGTATTGGGTATTATATTCCGTCATCCCATTACGGGAACCAGTATCATCCCAATACTATC
CGATGGTCGGATTGTCTTAATTCGTAGGCGAGACGATGGTTTATGGGCATTGCCCGGCGGTATGGTGGACTGGGGAGAAG
ATATTCCTACTACAGTCCGCCGTGAGCTTTTGGAGGAAACTGGCCTAGAATTGACAAAAATTAGGCGTTTGGTGGGAGTT
TACTCTTCACCAGACCGCGACCCCAGAATCCATTCGATTTGTGTTGTGGTTGAAGCCGAAGTAGAAGGGAAAATGGACAT
TCAGGATACCTTGGAAGTCATGGAAATCGAGGCTTTTACCCCTAGTTCCCTACCCCAAGGGCCAATGTCTCATGATCATG
CTCGACAAATACAGGATTACTTAAACGGATTAACAACGCTAGCATAA

Upstream 100 bases:

>100_bases
AGATTGTGCGAGTGGTAGACGGTTAAAAAACTCAACCATAGATATTTTTAGATTGAACGTTATTGCTTTTTTTAAATCAC
CAATCCAATCTACACGTAGT

Downstream 100 bases:

>100_bases
AAACTTATGTGAAATTTTGGGTTAAAGTTAACGATTCTGGATAAAGTCTGAATATTCTAATTAAGAATCGCAAATCCACA
GAAAGATAAACACTACATTA

Product: mutator protein

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MWRIGQTVLGIIFRHPITGTSIIPILSDGRIVLIRRRDDGLWALPGGMVDWGEDIPTTVRRELLEETGLELTKIRRLVGV
YSSPDRDPRIHSICVVVEAEVEGKMDIQDTLEVMEIEAFTPSSLPQGPMSHDHARQIQDYLNGLTTLA

Sequences:

>Translated_148_residues
MWRIGQTVLGIIFRHPITGTSIIPILSDGRIVLIRRRDDGLWALPGGMVDWGEDIPTTVRRELLEETGLELTKIRRLVGV
YSSPDRDPRIHSICVVVEAEVEGKMDIQDTLEVMEIEAFTPSSLPQGPMSHDHARQIQDYLNGLTTLA
>Mature_148_residues
MWRIGQTVLGIIFRHPITGTSIIPILSDGRIVLIRRRDDGLWALPGGMVDWGEDIPTTVRRELLEETGLELTKIRRLVGV
YSSPDRDPRIHSICVVVEAEVEGKMDIQDTLEVMEIEAFTPSSLPQGPMSHDHARQIQDYLNGLTTLA

Specific function: Unknown

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 16611; Mature: 16611

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRIGQTVLGIIFRHPITGTSIIPILSDGRIVLIRRRDDGLWALPGGMVDWGEDIPTTVR
CCCCHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCEEECCCCCCCCCCCCCHHHH
RELLEETGLELTKIRRLVGVYSSPDRDPRIHSICVVVEAEVEGKMDIQDTLEVMEIEAFT
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCC
PSSLPQGPMSHDHARQIQDYLNGLTTLA
CCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWRIGQTVLGIIFRHPITGTSIIPILSDGRIVLIRRRDDGLWALPGGMVDWGEDIPTTVR
CCCCHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCEEECCCCCCCCCCCCCHHHH
RELLEETGLELTKIRRLVGVYSSPDRDPRIHSICVVVEAEVEGKMDIQDTLEVMEIEAFT
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCCC
PSSLPQGPMSHDHARQIQDYLNGLTTLA
CCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9694840 [H]