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The map label for this gene is sigD [H]

Identifier: 17231302

GI number: 17231302

Start: 4607438

End: 4608436

Strand: Direct

Name: sigD [H]

Synonym: alr3810

Alternate gene names: 17231302

Gene position: 4607438-4608436 (Clockwise)

Preceding gene: 17231301

Following gene: 17231303

Centisome position: 71.84

GC content: 47.55

Gene sequence:

>999_bases
ATGACCCTACCAACAGAAACATCATCACCAAAGAGTAGCGCCATGAAGACCGCTCCAACAGCCACAGACCTCGTGCGGAC
TTACCTGCGTGAGATAGGACGTGTACCACTTTTAAGTCATGAAGAAGAAATTCGTTATGGTAAACAGGTACAGCGTTCCA
CAACGTTGCAAGAAATGCGAGAGGAATTGGCAACCCAGTCAGGGCGTGAACCAAGCGTAGAAGAGTGGGCAAAAGCGGCC
AATCTCAACCCAGCAGATTTGCTGGAAGCGATCGCCGATGGCGAAATAGCCAAGCGCAAAATGGTAGAAGCCAACTTGCG
GCTAGTGGTATCCGTTGCCAAAAAATATATTAAACGTAACGTCGATTTATTAGACCTCATCCAAGAAGGTAGTATTGGAA
TGCAACGGGGTGTAGAGAAATTTGACCCCACCAAGGGTTATAGATTTTCTACCTACGCCTACTGGTGGATACGTCAAGCC
ATCACGCGGGCGATCGCTGAAAAAGCGCGTACTATCCGCCTACCCATCCATATCACCGAGAAGCTGAACAAAATTAAAAA
AGCCCAGCGTCAGCTCTCCCAGAGATTGGGACGTGCGCCTACAGCCGGTGAACTAGCCAACGAATTAGAACTAACACCCA
AACAAGTTAGGGAATATTTAGAAAAAGCCCGTCTCCCCTTATCCTTAGATTTACGCTTAGGGGACAACTACGACACCGAA
CTAGGAGAAATGTTGGAAGATCCAGGCGCTTCTCCGGAAGACTTTGTTATGCAATCTTCCCTATCCAACGACCTAGAGGT
ACTGATGGAGCAATTAACGCCCCAGCAGAAAGAAGTAATCACACTCCGCTTTGGCTTAATCGATGGGCAAGCCCTAACTC
TAGCAAGAATCGGCGAAATACTTAACATCAGCCGCGAACGAGTCAGACAAATCGAAAGAGAAGCGCTTACCAAATTGCGT
AAGTCTAAAGCCAACATGGGTGAGTATTTGGCAAGTTAG

Upstream 100 bases:

>100_bases
CTATAACAGCCGACATCATCGGATGTATAAACCCTAAACGATCAAACAACAACATCCCAGGTTAACTGGGTAGCAACGGC
AAAGAGCATCTATTCAGTTA

Downstream 100 bases:

>100_bases
TCAGAGACGCGATTAATCGCGTCTGTACATTGGTCAGTAGTCAGATGTAAATCCTCTGTTTACATCTGACTGCTGACTTT
TTACTATTGACTAACAGGTG

Product: RNA polymerase sigma factor SigD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTLPTETSSPKSSAMKTAPTATDLVRTYLREIGRVPLLSHEEEIRYGKQVQRSTTLQEMREELATQSGREPSVEEWAKAA
NLNPADLLEAIADGEIAKRKMVEANLRLVVSVAKKYIKRNVDLLDLIQEGSIGMQRGVEKFDPTKGYRFSTYAYWWIRQA
ITRAIAEKARTIRLPIHITEKLNKIKKAQRQLSQRLGRAPTAGELANELELTPKQVREYLEKARLPLSLDLRLGDNYDTE
LGEMLEDPGASPEDFVMQSSLSNDLEVLMEQLTPQQKEVITLRFGLIDGQALTLARIGEILNISRERVRQIEREALTKLR
KSKANMGEYLAS

Sequences:

>Translated_332_residues
MTLPTETSSPKSSAMKTAPTATDLVRTYLREIGRVPLLSHEEEIRYGKQVQRSTTLQEMREELATQSGREPSVEEWAKAA
NLNPADLLEAIADGEIAKRKMVEANLRLVVSVAKKYIKRNVDLLDLIQEGSIGMQRGVEKFDPTKGYRFSTYAYWWIRQA
ITRAIAEKARTIRLPIHITEKLNKIKKAQRQLSQRLGRAPTAGELANELELTPKQVREYLEKARLPLSLDLRLGDNYDTE
LGEMLEDPGASPEDFVMQSSLSNDLEVLMEQLTPQQKEVITLRFGLIDGQALTLARIGEILNISRERVRQIEREALTKLR
KSKANMGEYLAS
>Mature_331_residues
TLPTETSSPKSSAMKTAPTATDLVRTYLREIGRVPLLSHEEEIRYGKQVQRSTTLQEMREELATQSGREPSVEEWAKAAN
LNPADLLEAIADGEIAKRKMVEANLRLVVSVAKKYIKRNVDLLDLIQEGSIGMQRGVEKFDPTKGYRFSTYAYWWIRQAI
TRAIAEKARTIRLPIHITEKLNKIKKAQRQLSQRLGRAPTAGELANELELTPKQVREYLEKARLPLSLDLRLGDNYDTEL
GEMLEDPGASPEDFVMQSSLSNDLEVLMEQLTPQQKEVITLRFGLIDGQALTLARIGEILNISRERVRQIEREALTKLRK
SKANMGEYLAS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=225, Percent_Identity=46.2222222222222, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1789098, Length=301, Percent_Identity=37.5415282392027, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1789871, Length=270, Percent_Identity=28.5185185185185, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788231, Length=206, Percent_Identity=28.1553398058252, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR017848
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 37633; Mature: 37502

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPTETSSPKSSAMKTAPTATDLVRTYLREIGRVPLLSHEEEIRYGKQVQRSTTLQEMR
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EELATQSGREPSVEEWAKAANLNPADLLEAIADGEIAKRKMVEANLRLVVSVAKKYIKRN
HHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VDLLDLIQEGSIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKARTIRLPIHITE
CHHHHHHHCCCCCHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCHHHH
KLNKIKKAQRQLSQRLGRAPTAGELANELELTPKQVREYLEKARLPLSLDLRLGDNYDTE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCHH
LGEMLEDPGASPEDFVMQSSLSNDLEVLMEQLTPQQKEVITLRFGLIDGQALTLARIGEI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCHHHHHHHHHH
LNISRERVRQIEREALTKLRKSKANMGEYLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLPTETSSPKSSAMKTAPTATDLVRTYLREIGRVPLLSHEEEIRYGKQVQRSTTLQEMR
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EELATQSGREPSVEEWAKAANLNPADLLEAIADGEIAKRKMVEANLRLVVSVAKKYIKRN
HHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VDLLDLIQEGSIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKARTIRLPIHITE
CHHHHHHHCCCCCHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCHHHH
KLNKIKKAQRQLSQRLGRAPTAGELANELELTPKQVREYLEKARLPLSLDLRLGDNYDTE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCHH
LGEMLEDPGASPEDFVMQSSLSNDLEVLMEQLTPQQKEVITLRFGLIDGQALTLARIGEI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCHHHHHHHHHH
LNISRERVRQIEREALTKLRKSKANMGEYLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA