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The map label for this gene is fabG [H]

Identifier: 17231297

GI number: 17231297

Start: 4597349

End: 4598104

Strand: Reverse

Name: fabG [H]

Synonym: all3805

Alternate gene names: 17231297

Gene position: 4598104-4597349 (Counterclockwise)

Preceding gene: 17231311

Following gene: 17231294

Centisome position: 71.69

GC content: 45.63

Gene sequence:

>756_bases
ATGCAAGCAATACGCCCACGCGTTATCTTGAATCATGAAGCTCTCTGGAGTTCATACATCATGAAAGGTAGACAAGTTCT
ACTTACAGGCGGTACTGGTGGACTAGGTTTAGGAGTCACACCAGTCGTCCTCGCCCAAGGTGCAAATCTGACCATTACTT
ACCGCAATCTCAAGGAAGTTGAACGCCTCAAAGAGGTTCTCCCGCCGGCGGATTTTGCCAGAGTTAACTTTCTTCCCGCT
AATTTGGAAGAAGAATCTTCTGTTGATAATCTCATCACCCGCATCGGTAGGGTAGATGTATTAATTCATCTTGTGGGTGG
CTTTTCGATGGGCAAAACTCACGAGTACAGTTATTACAGTTGGAAACGAGAATTTGAGATCAATTTAAATACAACTTTTT
TGGTTTGCAAATATAGCCTCAAAAGTATGTTAGACCACGGCTACGGACGTATTATCACTATCGGTTCTAAGGCTGCTGTG
GAACCATCCGGAGGATTAGCCGCCTATTCTGCGGCGAAGGCGGGTGTGGTAGCTTTCACAAAAGCGATCGCTGATGAAAC
GAAAGGTACAAACATCACCGCTAATGTTATCCTCCCCACAGTTATTGATACCCCCGCTAACCGTCAAGCAATGGGTACAG
AAAATGCCGACAAATGGGTAAAGCCTGAGTCTATTGGCGAATTAATCTGCTTTTTAGCCTCGGAAAAAGCCAAAGATATT
CGCGGCGCGGCTATTCCGATATATGGAGGGGTGTAG

Upstream 100 bases:

>100_bases
TAAGAATTGTAGGCGATCGCCGTACCAACTAGAAGCGACTGGGGAAGTAAGTATTATTCCCCTACACCCCTAAACCCCTA
CACCCCTAAATTTTACTCCG

Downstream 100 bases:

>100_bases
GGGTTTGGGGGTGTGAGGGTGTAAGAGAACAATTTTTTACTCCTCACTCCCTACTTCCCAGGACTTACGCACAGAGGTTA
TTTGTTCAGAAGGGGTATAA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MQAIRPRVILNHEALWSSYIMKGRQVLLTGGTGGLGLGVTPVVLAQGANLTITYRNLKEVERLKEVLPPADFARVNFLPA
NLEEESSVDNLITRIGRVDVLIHLVGGFSMGKTHEYSYYSWKREFEINLNTTFLVCKYSLKSMLDHGYGRIITIGSKAAV
EPSGGLAAYSAAKAGVVAFTKAIADETKGTNITANVILPTVIDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDI
RGAAIPIYGGV

Sequences:

>Translated_251_residues
MQAIRPRVILNHEALWSSYIMKGRQVLLTGGTGGLGLGVTPVVLAQGANLTITYRNLKEVERLKEVLPPADFARVNFLPA
NLEEESSVDNLITRIGRVDVLIHLVGGFSMGKTHEYSYYSWKREFEINLNTTFLVCKYSLKSMLDHGYGRIITIGSKAAV
EPSGGLAAYSAAKAGVVAFTKAIADETKGTNITANVILPTVIDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDI
RGAAIPIYGGV
>Mature_251_residues
MQAIRPRVILNHEALWSSYIMKGRQVLLTGGTGGLGLGVTPVVLAQGANLTITYRNLKEVERLKEVLPPADFARVNFLPA
NLEEESSVDNLITRIGRVDVLIHLVGGFSMGKTHEYSYYSWKREFEINLNTTFLVCKYSLKSMLDHGYGRIITIGSKAAV
EPSGGLAAYSAAKAGVVAFTKAIADETKGTNITANVILPTVIDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDI
RGAAIPIYGGV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=24.2677824267782, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254992, Length=200, Percent_Identity=25, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI66933014, Length=185, Percent_Identity=25.4054054054054, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4503817, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15277342, Length=147, Percent_Identity=30.6122448979592, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4504505, Length=229, Percent_Identity=25.3275109170306, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=23.1707317073171, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI4758504, Length=202, Percent_Identity=29.7029702970297, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=28.099173553719, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=25.6, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=24.901185770751, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=26.0162601626016, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=28.0632411067194, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=27.710843373494, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=22.9249011857708, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=241, Percent_Identity=27.8008298755187, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=28.1553398058252, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=23.4615384615385, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=27.4131274131274, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=30.4166666666667, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=25.6, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=26.6393442622951, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=24.5901639344262, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=23.5772357723577, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=24.901185770751, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=22.9838709677419, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=234, Percent_Identity=27.3504273504274, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27169; Mature: 27169

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIRPRVILNHEALWSSYIMKGRQVLLTGGTGGLGLGVTPVVLAQGANLTITYRNLKEV
CCCCCCEEEECHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHEEECCCCEEEEECCHHHH
ERLKEVLPPADFARVNFLPANLEEESSVDNLITRIGRVDVLIHLVGGFSMGKTHEYSYYS
HHHHHHCCCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCEEE
WKREFEINLNTTFLVCKYSLKSMLDHGYGRIITIGSKAAVEPSGGLAAYSAAKAGVVAFT
EEEEEEEECCCEEEEEEHHHHHHHHCCCCEEEEECCCCEECCCCCEEEHHHHHCCHHHHH
KAIADETKGTNITANVILPTVIDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDI
HHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHC
RGAAIPIYGGV
CCCEEEECCCC
>Mature Secondary Structure
MQAIRPRVILNHEALWSSYIMKGRQVLLTGGTGGLGLGVTPVVLAQGANLTITYRNLKEV
CCCCCCEEEECHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHEEECCCCEEEEECCHHHH
ERLKEVLPPADFARVNFLPANLEEESSVDNLITRIGRVDVLIHLVGGFSMGKTHEYSYYS
HHHHHHCCCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCEEE
WKREFEINLNTTFLVCKYSLKSMLDHGYGRIITIGSKAAVEPSGGLAAYSAAKAGVVAFT
EEEEEEEECCCEEEEEEHHHHHHHHCCCCEEEEECCCCEECCCCCEEEHHHHHCCHHHHH
KAIADETKGTNITANVILPTVIDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDI
HHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHC
RGAAIPIYGGV
CCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA