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The map label for this gene is vanY [H]

Identifier: 17231194

GI number: 17231194

Start: 4470847

End: 4471656

Strand: Reverse

Name: vanY [H]

Synonym: all3702

Alternate gene names: 17231194

Gene position: 4471656-4470847 (Counterclockwise)

Preceding gene: 17231196

Following gene: 17231189

Centisome position: 69.72

GC content: 47.16

Gene sequence:

>810_bases
GTGAATAAAGCTGGGTTTTCTGGAGAGCCACGCGATCCATTTGATGAACTTAGTGATGATATCCCAGTAGCCTTACGCGA
CACTCCTGGTATCACACCTAAACAACGCTTACAACGCCTGATTTTCGTGACGGGTGGAGTAGGTGCGTTTGTGATACTGG
CGATTGTTAGTGGGTTTGTTTTTTTTATCACCACGCCTAAAAAAACTACTGAGTCCCAGCCTTCACCAGCTATTGCTGAT
GCTACACCAATGCCTACAGCCAGCAACCCGGCTGATCTGCAAGCTATACTAGGTCATTTGGCTTACCCAGAGGCTCCAGA
GTCAGAATTAGTGCCAATCAGTAGGGATGGACGCATCCGAATGCGTAGAAATGCGGCTCAACGGTTCCAAGAAATGGCAC
AGGCGGCGCGGACTGCGGGTGTCATCTTAATGCCTATTTCCGGCTTTCGTTCTGTAAAAGAGCAAGAGCAATTATTTTTT
GCTATTGGCGCTCAACGTAATCAAACCCCAGCCCAAAGAGCAGCCCTCAGCGCTCCCCCTGGTCATAGTGAACACCACAC
AGGTTACGCGGTGGATATTGGGGATGGCGCAGCACCGACAACTAATTTGCAAGCTATTTTTGAAAATACCAGAGCTTTTA
AATGGCTAGAGGCGAATGCAGCTCGCTTTGGTTTTGAGATGTCTTTCCCCATGGATAATTCTCAAGGAGTGAGTTATGAA
CCTTGGCACTGGCGTTTTGTAGGCGATCGCGATAGCCTAGAAACGTTTTATAAAGCGAGAAATTTAAAACCTGTTAAAAC
ACCACAATAA

Upstream 100 bases:

>100_bases
GTTGCGCCTAAGAATTATAGATGTAAAATGCTACCCAACAAGCTTATTCTTATCAAGTCTACAATTTTTATGAGAGTTCC
ACAAAACCAGGAGTTGACCT

Downstream 100 bases:

>100_bases
TATAGGGTAAAAGTCCGAGAACAGAATCAATCTAGGGGCTTCTAACATTATTGCTCAAAACCTATTTTCTCGGTCTTCAT
AGGGTCCCAGAAATCTTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNKAGFSGEPRDPFDELSDDIPVALRDTPGITPKQRLQRLIFVTGGVGAFVILAIVSGFVFFITTPKKTTESQPSPAIAD
ATPMPTASNPADLQAILGHLAYPEAPESELVPISRDGRIRMRRNAAQRFQEMAQAARTAGVILMPISGFRSVKEQEQLFF
AIGAQRNQTPAQRAALSAPPGHSEHHTGYAVDIGDGAAPTTNLQAIFENTRAFKWLEANAARFGFEMSFPMDNSQGVSYE
PWHWRFVGDRDSLETFYKARNLKPVKTPQ

Sequences:

>Translated_269_residues
MNKAGFSGEPRDPFDELSDDIPVALRDTPGITPKQRLQRLIFVTGGVGAFVILAIVSGFVFFITTPKKTTESQPSPAIAD
ATPMPTASNPADLQAILGHLAYPEAPESELVPISRDGRIRMRRNAAQRFQEMAQAARTAGVILMPISGFRSVKEQEQLFF
AIGAQRNQTPAQRAALSAPPGHSEHHTGYAVDIGDGAAPTTNLQAIFENTRAFKWLEANAARFGFEMSFPMDNSQGVSYE
PWHWRFVGDRDSLETFYKARNLKPVKTPQ
>Mature_269_residues
MNKAGFSGEPRDPFDELSDDIPVALRDTPGITPKQRLQRLIFVTGGVGAFVILAIVSGFVFFITTPKKTTESQPSPAIAD
ATPMPTASNPADLQAILGHLAYPEAPESELVPISRDGRIRMRRNAAQRFQEMAQAARTAGVILMPISGFRSVKEQEQLFF
AIGAQRNQTPAQRAALSAPPGHSEHHTGYAVDIGDGAAPTTNLQAIFENTRAFKWLEANAARFGFEMSFPMDNSQGVSYE
PWHWRFVGDRDSLETFYKARNLKPVKTPQ

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: COG1876

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 29558; Mature: 29558

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAGFSGEPRDPFDELSDDIPVALRDTPGITPKQRLQRLIFVTGGVGAFVILAIVSGFV
CCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHEEEECCHHHHHHHHHHHCCE
FFITTPKKTTESQPSPAIADATPMPTASNPADLQAILGHLAYPEAPESELVPISRDGRIR
EEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCEE
MRRNAAQRFQEMAQAARTAGVILMPISGFRSVKEQEQLFFAIGAQRNQTPAQRAALSAPP
HHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHEEEEECCCCCCCHHHHHHCCCCC
GHSEHHTGYAVDIGDGAAPTTNLQAIFENTRAFKWLEANAARFGFEMSFPMDNSQGVSYE
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHEEEEECCHHHHCEEEECCCCCCCCCCCC
PWHWRFVGDRDSLETFYKARNLKPVKTPQ
CEEEEEECCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNKAGFSGEPRDPFDELSDDIPVALRDTPGITPKQRLQRLIFVTGGVGAFVILAIVSGFV
CCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCHHHHHHHHEEEECCHHHHHHHHHHHCCE
FFITTPKKTTESQPSPAIADATPMPTASNPADLQAILGHLAYPEAPESELVPISRDGRIR
EEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCEE
MRRNAAQRFQEMAQAARTAGVILMPISGFRSVKEQEQLFFAIGAQRNQTPAQRAALSAPP
HHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHEEEEECCCCCCCHHHHHHCCCCC
GHSEHHTGYAVDIGDGAAPTTNLQAIFENTRAFKWLEANAARFGFEMSFPMDNSQGVSYE
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHEEEEECCHHHHCEEEECCCCCCCCCCCC
PWHWRFVGDRDSLETFYKARNLKPVKTPQ
CEEEEEECCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1398115; 8380148 [H]