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The map label for this gene is 17231126

Identifier: 17231126

GI number: 17231126

Start: 4385664

End: 4386722

Strand: Reverse

Name: 17231126

Synonym: all3634

Alternate gene names: NA

Gene position: 4386722-4385664 (Counterclockwise)

Preceding gene: 17231127

Following gene: 17231125

Centisome position: 68.4

GC content: 40.51

Gene sequence:

>1059_bases
ATGAAAACTAAATTCATCGCGGCAAGTTTTATTACACTCTCCTTGATGTCGCCGCTAAAAGCTTCGGCTGCAAATTTTAC
TGGGCTTTACGTATTTGGCGATAGCATATCTGATACAGGTAATACATTTCAACTTTCTGGTGGGTTAGTTGATCCATCAA
GTGCTATTCCTCCCAGTCCACCGTATGAGCCGGGGCGTTTTTCTAATGGTTCAATATGGGTAGATTATGTAGGAGACACG
TTAGGTTTAACAACCACGCCTATCACTAATCTAGTTCCTGATTTAAACTTTAGTCGTCCTCTGAATACACCCTTTCCCAC
ACAAGGTATTAACTTTGCTATCGGTGGTGCTAATTCCGGTGAAGGTAACTCTTTTGGTTTCCCTTTACCTGGAGTTTTAC
AGCAAGTATCTGCTTTTCAAGCGTTACTACAGGTTAATCAACAAAGCCTTGATCCTAATGCACTCTATGCTGTGTCTGGT
GGTGCAAATGACTATCTCTTTCCCCCTCGGTCTAATGATCCCAATAGACCCCAACCCTACACGAATATTTCCCAGGCTGT
AAGTAACCTAGCGGCAATAGGTGCAAAAAATATTTTAGTGTTCAACTTGCCCGATTTGGGCAGGATTCCAGCATCGGGAA
CAAATGGTCGCAATCCCGCAGCACTGACTCAAGCGACTCTAGATTTCAACTCAAACTTAGCCAAAAATCTAGACGAAATT
CGGAACACCCAACAAGTAAATATCATTGAAATTGATATTTATTCTTTAGTTAATCGTGTGCTTGCGACTCCAAGTGAATT
TGGTTTTGAAAATGTAACTGATGCTTGTCTATCTCAGTTTCCTAACTGTATTAACGACCCCAGTAAATATTTTTTCTGGG
ATGATGTTCACCCAACAACTGATGGTCATAAATTAGTAGCAGAATCAGTCTTAGCGGCAACAACTCCTGAGTCTTCAACC
ACAATTGGTGTACTATTTCTAGGTGTATTGGGTGCAATGAGCAACATCAAACGCTTACAGAGAAAATCAATTAAATTTTC
TGTTCAGAAAAAAGGTTAA

Upstream 100 bases:

>100_bases
TGTACAGGGTGTGGAAAAAATTAATCACTTAGTTAACAGCATTGTTGGTTGTAACTTTATGAAACAAGCTCAACTATAAA
ATTTCATTATTTCACTAAAA

Downstream 100 bases:

>100_bases
TACTAGATAATTAGCTGTCTCTTGCTCATTCATTTATTTGAATGAGCGCTATTTTTTAAGTATATAAACACCATAAAATA
CCCATGCAGTTCTAGTTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: TL; Atypical phospholipase; Lecithin-dependent hemolysin; LDH; Lysophospholipase; Phospholipase A2 [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKTKFIAASFITLSLMSPLKASAANFTGLYVFGDSISDTGNTFQLSGGLVDPSSAIPPSPPYEPGRFSNGSIWVDYVGDT
LGLTTTPITNLVPDLNFSRPLNTPFPTQGINFAIGGANSGEGNSFGFPLPGVLQQVSAFQALLQVNQQSLDPNALYAVSG
GANDYLFPPRSNDPNRPQPYTNISQAVSNLAAIGAKNILVFNLPDLGRIPASGTNGRNPAALTQATLDFNSNLAKNLDEI
RNTQQVNIIEIDIYSLVNRVLATPSEFGFENVTDACLSQFPNCINDPSKYFFWDDVHPTTDGHKLVAESVLAATTPESST
TIGVLFLGVLGAMSNIKRLQRKSIKFSVQKKG

Sequences:

>Translated_352_residues
MKTKFIAASFITLSLMSPLKASAANFTGLYVFGDSISDTGNTFQLSGGLVDPSSAIPPSPPYEPGRFSNGSIWVDYVGDT
LGLTTTPITNLVPDLNFSRPLNTPFPTQGINFAIGGANSGEGNSFGFPLPGVLQQVSAFQALLQVNQQSLDPNALYAVSG
GANDYLFPPRSNDPNRPQPYTNISQAVSNLAAIGAKNILVFNLPDLGRIPASGTNGRNPAALTQATLDFNSNLAKNLDEI
RNTQQVNIIEIDIYSLVNRVLATPSEFGFENVTDACLSQFPNCINDPSKYFFWDDVHPTTDGHKLVAESVLAATTPESST
TIGVLFLGVLGAMSNIKRLQRKSIKFSVQKKG
>Mature_352_residues
MKTKFIAASFITLSLMSPLKASAANFTGLYVFGDSISDTGNTFQLSGGLVDPSSAIPPSPPYEPGRFSNGSIWVDYVGDT
LGLTTTPITNLVPDLNFSRPLNTPFPTQGINFAIGGANSGEGNSFGFPLPGVLQQVSAFQALLQVNQQSLDPNALYAVSG
GANDYLFPPRSNDPNRPQPYTNISQAVSNLAAIGAKNILVFNLPDLGRIPASGTNGRNPAALTQATLDFNSNLAKNLDEI
RNTQQVNIIEIDIYSLVNRVLATPSEFGFENVTDACLSQFPNCINDPSKYFFWDDVHPTTDGHKLVAESVLAATTPESST
TIGVLFLGVLGAMSNIKRLQRKSIKFSVQKKG

Specific function: Phospholipase hydrolyzing both fatty acid esters of phospholipid, i.e., it hydrolyzes phosphatidylcholine (PC) to lysophosphatidylcholine (LPC) and then LPC to glycerophosphorylcholine (GPC) [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: NA

Molecular weight: Translated: 37613; Mature: 37613

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKFIAASFITLSLMSPLKASAANFTGLYVFGDSISDTGNTFQLSGGLVDPSSAIPPSP
CCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCEECCCCCCCCCC
PYEPGRFSNGSIWVDYVGDTLGLTTTPITNLVPDLNFSRPLNTPFPTQGINFAIGGANSG
CCCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
EGNSFGFPLPGVLQQVSAFQALLQVNQQSLDPNALYAVSGGANDYLFPPRSNDPNRPQPY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
TNISQAVSNLAAIGAKNILVFNLPDLGRIPASGTNGRNPAALTQATLDFNSNLAKNLDEI
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHH
RNTQQVNIIEIDIYSLVNRVLATPSEFGFENVTDACLSQFPNCINDPSKYFFWDDVHPTT
CCCCCEEEEEEEHHHHHHHHHCCCHHCCHHHHHHHHHHHCCHHHCCCCCEEEECCCCCCC
DGHKLVAESVLAATTPESSTTIGVLFLGVLGAMSNIKRLQRKSIKFSVQKKG
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MKTKFIAASFITLSLMSPLKASAANFTGLYVFGDSISDTGNTFQLSGGLVDPSSAIPPSP
CCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCEECCCCCCCCCC
PYEPGRFSNGSIWVDYVGDTLGLTTTPITNLVPDLNFSRPLNTPFPTQGINFAIGGANSG
CCCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
EGNSFGFPLPGVLQQVSAFQALLQVNQQSLDPNALYAVSGGANDYLFPPRSNDPNRPQPY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
TNISQAVSNLAAIGAKNILVFNLPDLGRIPASGTNGRNPAALTQATLDFNSNLAKNLDEI
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHH
RNTQQVNIIEIDIYSLVNRVLATPSEFGFENVTDACLSQFPNCINDPSKYFFWDDVHPTT
CCCCCEEEEEEEHHHHHHHHHCCCHHCCHHHHHHHHHHHCCHHHCCCCCEEEECCCCCCC
DGHKLVAESVLAATTPESSTTIGVLFLGVLGAMSNIKRLQRKSIKFSVQKKG
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3508495; 12620739; 1791426 [H]