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The map label for this gene is resE [H]

Identifier: 17231079

GI number: 17231079

Start: 4332137

End: 4333564

Strand: Reverse

Name: resE [H]

Synonym: all3587

Alternate gene names: 17231079

Gene position: 4333564-4332137 (Counterclockwise)

Preceding gene: 17231087

Following gene: 17231078

Centisome position: 67.57

GC content: 42.37

Gene sequence:

>1428_bases
ATGTTTCAAGCTACTCGTCGCCGTCTGGCTATTTGGTACACTGCGGTAACTGCGGTATTGTTGCTGCTGTTTGCTAGTGG
TGTGTATTTATATGTCCGTAGTACTTTGGTGGAACGGATCGACGATACGCTCAATCATGTAGTGGAAATAGTCGAGCGAT
CGCTTGTCATTGAACCAGTGAACGGTGAGCCTGAGAAGCTACGTATTAATGTAGAGGCAAGTTTTCGCAACAATGCCAAT
ACTGTAGAAGATGATCACATTGATCTGGAGTGGTTTAGCTCCACTGGTGAATTAATCTGGTCAACTTTTTCTGAACCTTT
AAATATTCCTATTCACAGTAACCGCACAGGTGAAACTGTTCATGTTTTTAAACAAGACAGATGGATAAATCCAGGAACGC
AAAAGCTTCTAATCCCCACTCAAGATTCAGGACTACTATTGCGACAAGTCACACAACGAGTGGAAATTGGACGGCAAGTT
TTGGGATATCTGCGTGTGAGTCATCCTTGGTTTGAAGTAACTAAACCGAGTCGCCAGTTAATTTTTGACTTGGCGCTGGG
TACTGGGTTAATGGTGATTTCTGTCGCGGCTAGTGGATGGTTTCTTTCGGGTAAAGCAATGGAACCAGTTGGTGAATCTT
ACCAACGTCTCAAGCAATTTACTGCGGATGCTTCCCATGAACTCAGAAGTCCCATCACTTTGATTCAAACTAATGTCCAA
GTTGCTTTGGCTGACTTGGATTTGACTGAATCTGAGGTTACTACCTCTTCCAATTATCGCCAACAGTTAAAGGTGGTGGA
ACGGCTAACGCAGCGTTTGGGTAAGTTAGTCAATGACTTATTATTTCTAGCACGTCAGGATGGTGGTGTAAGCAGAGATG
GTTTTTCATCTTGTCCGCTTGATGCTTTACTGATGGATGTGGTGGAAGAACAACAGCTTGTAGCTACAGAAAAAGCAATT
ACTCTGAATCTGCACTTAATTGATCCTGCTGATTTTGAAACTAGCCCTGAAATATTAGAACATTGGTTCACACTGATAGG
GAATTGGGATCAACTGATGCGATTATTTACTAATTTGATTGGTAACGCTTTACACTATACCCCCGCAGGTGGTGCGGTAA
ATGTGGAACTAATGCGTATAGACAAGGTTCGCTATAATACATCACAGTTACAAATTAAGGTGAGTGATACGGGAATTGGT
ATTCCGACTGAAGCATTACCGCGATTATTTGATCGTTTTTATCGAGTTGATCCTGCACGCACTCATAAGAGTGGGAATGC
AGGTAAAGATAATGCTACAGGTTCAGGATTAGGACTAGCGATCGCGCAAGCTATTGTGGAACATCACCACGGTAACATTC
TAGTCGAAAGCACTTTAGGTAACGGTACTACTTTTATTGTCACTTTACCCATAACTCTAGAGTCTTAA

Upstream 100 bases:

>100_bases
TTTGCCATTTTATTTTTTTTACGCTGAGGGATGTAGAGTATTTGCAAGGTTCATTCAAAAAGAATTATTTTGATAGAATC
AGGTTTTTTTGTATAGATCA

Downstream 100 bases:

>100_bases
TTTGATAATTGATATTTGTTTCCTGTGATAGATGAATTCTACTAAATTTACATACTAATTTGTTTAGTAAGGCTTGCATT
CTTTAGCCATAAATATTGCA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MFQATRRRLAIWYTAVTAVLLLLFASGVYLYVRSTLVERIDDTLNHVVEIVERSLVIEPVNGEPEKLRINVEASFRNNAN
TVEDDHIDLEWFSSTGELIWSTFSEPLNIPIHSNRTGETVHVFKQDRWINPGTQKLLIPTQDSGLLLRQVTQRVEIGRQV
LGYLRVSHPWFEVTKPSRQLIFDLALGTGLMVISVAASGWFLSGKAMEPVGESYQRLKQFTADASHELRSPITLIQTNVQ
VALADLDLTESEVTTSSNYRQQLKVVERLTQRLGKLVNDLLFLARQDGGVSRDGFSSCPLDALLMDVVEEQQLVATEKAI
TLNLHLIDPADFETSPEILEHWFTLIGNWDQLMRLFTNLIGNALHYTPAGGAVNVELMRIDKVRYNTSQLQIKVSDTGIG
IPTEALPRLFDRFYRVDPARTHKSGNAGKDNATGSGLGLAIAQAIVEHHHGNILVESTLGNGTTFIVTLPITLES

Sequences:

>Translated_475_residues
MFQATRRRLAIWYTAVTAVLLLLFASGVYLYVRSTLVERIDDTLNHVVEIVERSLVIEPVNGEPEKLRINVEASFRNNAN
TVEDDHIDLEWFSSTGELIWSTFSEPLNIPIHSNRTGETVHVFKQDRWINPGTQKLLIPTQDSGLLLRQVTQRVEIGRQV
LGYLRVSHPWFEVTKPSRQLIFDLALGTGLMVISVAASGWFLSGKAMEPVGESYQRLKQFTADASHELRSPITLIQTNVQ
VALADLDLTESEVTTSSNYRQQLKVVERLTQRLGKLVNDLLFLARQDGGVSRDGFSSCPLDALLMDVVEEQQLVATEKAI
TLNLHLIDPADFETSPEILEHWFTLIGNWDQLMRLFTNLIGNALHYTPAGGAVNVELMRIDKVRYNTSQLQIKVSDTGIG
IPTEALPRLFDRFYRVDPARTHKSGNAGKDNATGSGLGLAIAQAIVEHHHGNILVESTLGNGTTFIVTLPITLES
>Mature_475_residues
MFQATRRRLAIWYTAVTAVLLLLFASGVYLYVRSTLVERIDDTLNHVVEIVERSLVIEPVNGEPEKLRINVEASFRNNAN
TVEDDHIDLEWFSSTGELIWSTFSEPLNIPIHSNRTGETVHVFKQDRWINPGTQKLLIPTQDSGLLLRQVTQRVEIGRQV
LGYLRVSHPWFEVTKPSRQLIFDLALGTGLMVISVAASGWFLSGKAMEPVGESYQRLKQFTADASHELRSPITLIQTNVQ
VALADLDLTESEVTTSSNYRQQLKVVERLTQRLGKLVNDLLFLARQDGGVSRDGFSSCPLDALLMDVVEEQQLVATEKAI
TLNLHLIDPADFETSPEILEHWFTLIGNWDQLMRLFTNLIGNALHYTPAGGAVNVELMRIDKVRYNTSQLQIKVSDTGIG
IPTEALPRLFDRFYRVDPARTHKSGNAGKDNATGSGLGLAIAQAIVEHHHGNILVESTLGNGTTFIVTLPITLES

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=33.6996336996337, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786600, Length=254, Percent_Identity=31.1023622047244, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788393, Length=260, Percent_Identity=29.6153846153846, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=30.1587301587302, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=30.0395256916996, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=28.4671532846715, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788549, Length=315, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789403, Length=243, Percent_Identity=32.0987654320988, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788279, Length=278, Percent_Identity=26.2589928057554, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=27.037037037037, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=24.609375, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=259, Percent_Identity=25.4826254826255, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=25.7936507936508, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=25.1937984496124, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53042; Mature: 53042

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQATRRRLAIWYTAVTAVLLLLFASGVYLYVRSTLVERIDDTLNHVVEIVERSLVIEPV
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
NGEPEKLRINVEASFRNNANTVEDDHIDLEWFSSTGELIWSTFSEPLNIPIHSNRTGETV
CCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCCCEECCCCCCEE
HVFKQDRWINPGTQKLLIPTQDSGLLLRQVTQRVEIGRQVLGYLRVSHPWFEVTKPSRQL
EEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHH
IFDLALGTGLMVISVAASGWFLSGKAMEPVGESYQRLKQFTADASHELRSPITLIQTNVQ
HHHHHHCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCEEEEECCEE
VALADLDLTESEVTTSSNYRQQLKVVERLTQRLGKLVNDLLFLARQDGGVSRDGFSSCPL
EEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
DALLMDVVEEQQLVATEKAITLNLHLIDPADFETSPEILEHWFTLIGNWDQLMRLFTNLI
HHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
GNALHYTPAGGAVNVELMRIDKVRYNTSQLQIKVSDTGIGIPTEALPRLFDRFYRVDPAR
CCCEEECCCCCEEEEEEEEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHH
THKSGNAGKDNATGSGLGLAIAQAIVEHHHGNILVESTLGNGTTFIVTLPITLES
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEECC
>Mature Secondary Structure
MFQATRRRLAIWYTAVTAVLLLLFASGVYLYVRSTLVERIDDTLNHVVEIVERSLVIEPV
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
NGEPEKLRINVEASFRNNANTVEDDHIDLEWFSSTGELIWSTFSEPLNIPIHSNRTGETV
CCCCCEEEEEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCCCEECCCCCCEE
HVFKQDRWINPGTQKLLIPTQDSGLLLRQVTQRVEIGRQVLGYLRVSHPWFEVTKPSRQL
EEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHH
IFDLALGTGLMVISVAASGWFLSGKAMEPVGESYQRLKQFTADASHELRSPITLIQTNVQ
HHHHHHCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHCCEEEEECCEE
VALADLDLTESEVTTSSNYRQQLKVVERLTQRLGKLVNDLLFLARQDGGVSRDGFSSCPL
EEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
DALLMDVVEEQQLVATEKAITLNLHLIDPADFETSPEILEHWFTLIGNWDQLMRLFTNLI
HHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
GNALHYTPAGGAVNVELMRIDKVRYNTSQLQIKVSDTGIGIPTEALPRLFDRFYRVDPAR
CCCEEECCCCCEEEEEEEEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHH
THKSGNAGKDNATGSGLGLAIAQAIVEHHHGNILVESTLGNGTTFIVTLPITLES
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]