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The map label for this gene is ppa

Identifier: 17231062

GI number: 17231062

Start: 4312098

End: 4312607

Strand: Reverse

Name: ppa

Synonym: all3570

Alternate gene names: 17231062

Gene position: 4312607-4312098 (Counterclockwise)

Preceding gene: 17231064

Following gene: 17231061

Centisome position: 67.24

GC content: 41.37

Gene sequence:

>510_bases
GTGGACTTATCCCGTATTCCAGCACAACCCAAACCAGGTGTCATCAATATTCTGATTGAAATTGCTGGTGGTAGTCAAAA
TAAATACGAATTTGATAAAGACCTGGAAGCCTTTGCTCTAGACCGAGTGTTGTATTCTTCGGTTAAGTATCCTTATGATT
ATGGTTTTGTCCCGAATACCTTAGCTGATGATGGCGATCCCCTGGATGGTATGGTAATTATTGATGAGCCAACCTTTCCT
GGTTGTGTCATCGCGGCCAGACCAATTGGCTTTTTGGAAATGATTGATGGTGGCGATCGCGATGAGAAAATTTTAGCAGT
ACCTGACAAAGACCCCCGCTACGCTCACGTAAAATCTTTGAATGACGTAGCCCCACATCGCTTGGATGAAATAGCTGAGT
TTTTCCGTAGTTACAAAAATTTAGAAAAAAAAGTAACTCAAATCCTCGGTTGGCAAGATGTTGATCAAGTGAAAGCTCTA
GTTGACCAATCCATTAAAGCTTACAAGTAA

Upstream 100 bases:

>100_bases
CATTTAGATAAATACTTTGGGAAGAAGTCCATCTTGGCCATAAAATTCTACACGGGGAGTATGTCCCCAATGCACTTAAT
AGTTAAGACAGGAGTTTTTT

Downstream 100 bases:

>100_bases
TAATGGGGAGTAGGGATTGGGGACTGGGGATTGGGGATTGGGGATTGGGCGGAAAATATTGCAGTCAGTTCTTCCCCTAC
CTCCCCTGCTCCCTGCTTCT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MDLSRIPAQPKPGVINILIEIAGGSQNKYEFDKDLEAFALDRVLYSSVKYPYDYGFVPNTLADDGDPLDGMVIIDEPTFP
GCVIAARPIGFLEMIDGGDRDEKILAVPDKDPRYAHVKSLNDVAPHRLDEIAEFFRSYKNLEKKVTQILGWQDVDQVKAL
VDQSIKAYK

Sequences:

>Translated_169_residues
MDLSRIPAQPKPGVINILIEIAGGSQNKYEFDKDLEAFALDRVLYSSVKYPYDYGFVPNTLADDGDPLDGMVIIDEPTFP
GCVIAARPIGFLEMIDGGDRDEKILAVPDKDPRYAHVKSLNDVAPHRLDEIAEFFRSYKNLEKKVTQILGWQDVDQVKAL
VDQSIKAYK
>Mature_169_residues
MDLSRIPAQPKPGVINILIEIAGGSQNKYEFDKDLEAFALDRVLYSSVKYPYDYGFVPNTLADDGDPLDGMVIIDEPTFP
GCVIAARPIGFLEMIDGGDRDEKILAVPDKDPRYAHVKSLNDVAPHRLDEIAEFFRSYKNLEKKVTQILGWQDVDQVKAL
VDQSIKAYK

Specific function: Hydrolyzes PPi generated in anabolic reactions

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=174, Percent_Identity=38.5057471264368, Blast_Score=109, Evalue=8e-26,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_NOSS1 (P80562)

Other databases:

- EMBL:   AJ252206
- EMBL:   BA000019
- PIR:   AC2252
- RefSeq:   NP_487610.1
- ProteinModelPortal:   P80562
- SMR:   P80562
- STRING:   P80562
- GeneID:   1107168
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all3570
- NMPDR:   fig|103690.1.peg.3877
- eggNOG:   COG0221
- HOGENOM:   HBG529150
- OMA:   PVALMKM
- PhylomeDB:   P80562
- ProtClustDB:   CLSK895996
- BioCyc:   NSP103690:ALL3570-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 18961; Mature: 18961

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSRIPAQPKPGVINILIEIAGGSQNKYEFDKDLEAFALDRVLYSSVKYPYDYGFVPNT
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LADDGDPLDGMVIIDEPTFPGCVIAARPIGFLEMIDGGDRDEKILAVPDKDPRYAHVKSL
CCCCCCCCCCEEEEECCCCCCEEEEECCCCCEEECCCCCCCCEEEECCCCCCCCHHHHHH
NDVAPHRLDEIAEFFRSYKNLEKKVTQILGWQDVDQVKALVDQSIKAYK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLSRIPAQPKPGVINILIEIAGGSQNKYEFDKDLEAFALDRVLYSSVKYPYDYGFVPNT
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LADDGDPLDGMVIIDEPTFPGCVIAARPIGFLEMIDGGDRDEKILAVPDKDPRYAHVKSL
CCCCCCCCCCEEEEECCCCCCEEEEECCCCCEEECCCCCCCCEEEECCCCCCCCHHHHHH
NDVAPHRLDEIAEFFRSYKNLEKKVTQILGWQDVDQVKALVDQSIKAYK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840