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The map label for this gene is atoS [H]

Identifier: 17231039

GI number: 17231039

Start: 4276128

End: 4277504

Strand: Direct

Name: atoS [H]

Synonym: alr3547

Alternate gene names: 17231039

Gene position: 4276128-4277504 (Clockwise)

Preceding gene: 17231038

Following gene: 17231040

Centisome position: 66.67

GC content: 38.2

Gene sequence:

>1377_bases
ATGCTCGCTAATCAAAGCGTGAAAAACGGTCATGATTTGAGCCTGAAATTAGATTCTACGTTACAAGAATTACCTGTGTG
GGATGTTGAGGTGGAAATTCATCTTCCAGGTAACAAATTGATTAGCTTTTTTGAGCATGAGCCTTTATTGCCAGGAGTCA
TTTTAACTGATAATCAGAAATTTGTAGGGATGATTTCACGACAGCGATTTTTTGAGTGTATGAGTCGTCCTTATAGTTTT
GGCTTGTTTTCGATGCGCCCGATTGAAAGTCTCTACAATTTTCTCCAAGCACAAATTTTTATCTTTCCTGCCCATAAGTT
AGTAACAGAAACTACTCAAGAAGCATTGCAGCGATCACCTCAATTTGTCTATGAACCAATTTTAGTGAAAAGTGCATCGG
GAAAGCATGAGGTACTCGATTTCCATCAGCTGCTTTTAGCTAACTCCCAAATTCATGCTCTCACCCTAGAAAAACTACAA
CACGTCAAAAAACAATCCCGAATAGCTAAGGCAGGATTTCGTGACCTGCAAAATAACTATACTCAACTATTGCAAAATGA
GAAAATGGCGGCTTTAGGTCAGTTGGTCGCAGGTATTGCTCATGAAGTTAATAATCCCATCAACTTTATTGCTGGTAATC
TTGTCCATACTATTGACTACACTCAGCAATTACTCAACCTCATCAATTTATACCAACATAATTATCCCCATCCTGTAGAG
GAAATTACAACTGCGATCGCTGAAAGTGAACTGGGCTTTATTAGCCATGATTTACCTAATCTACTAACTTCTATGCGGAG
TGGGTGCGATCGGATCGTACAAATTATTCGCTCTTTACGCAATTTCTCTCGTCTGGATGAATCTGATAGAAAACTGGTGG
ATATTCATGAAGGTATTGATAGCACTTTGCTGATTTTACAAAGTCGGCTCAAAAACCCAAACATTACTCACCCTATTAAC
GTTATCAAAGAATATGAGAACCTGCCTTTAGTTGATTGCTATGCTGGTTTACTCAATCAAGTATTTATGAATCTTCTCAG
CAATGCTATTGATGCTTTGGAAGAAGCTATAGTCAAATATTCAGGAATGGTAACCAAGCCACAAATTATCATTCGGACAG
AAATTATAGATGATCAGCAAGTAGTAATTCGCATTGCTGACAACGGGATAGGAATCCCAGAAGAGGCAAAACAGCGATTG
TTTGACCCATTTTTTACGACTAAGCCTGTAGGTAAAGGTACTGGTTTAGGTTTATCTATCTGCCATCAGATTATCGTTGA
GAAACATGGTGGACAGATGGATTGTATATCTAGTTTAGGAAAAGGAGCCGAGTTCATTATTAAAATTCCACTCAAATTTA
AAGTAGTCGGCAAATGA

Upstream 100 bases:

>100_bases
AAACTAAATATGGGAATACTGCTTTTTGAGTAATTGGCTGAACTGTAATTGTTCGGAATGGAAAGTAGCAAAAATACCTG
AGGGCTAAAGGAACAAAATT

Downstream 100 bases:

>100_bases
ATCAAGATTTTTACACAGAATACTTGCGTATATTGACTAGACCGTGTCAGGATCAATCTGCATGAACCAATAAAGTAATA
TCTTATGAGAAAAAAATGGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLANQSVKNGHDLSLKLDSTLQELPVWDVEVEIHLPGNKLISFFEHEPLLPGVILTDNQKFVGMISRQRFFECMSRPYSF
GLFSMRPIESLYNFLQAQIFIFPAHKLVTETTQEALQRSPQFVYEPILVKSASGKHEVLDFHQLLLANSQIHALTLEKLQ
HVKKQSRIAKAGFRDLQNNYTQLLQNEKMAALGQLVAGIAHEVNNPINFIAGNLVHTIDYTQQLLNLINLYQHNYPHPVE
EITTAIAESELGFISHDLPNLLTSMRSGCDRIVQIIRSLRNFSRLDESDRKLVDIHEGIDSTLLILQSRLKNPNITHPIN
VIKEYENLPLVDCYAGLLNQVFMNLLSNAIDALEEAIVKYSGMVTKPQIIIRTEIIDDQQVVIRIADNGIGIPEEAKQRL
FDPFFTTKPVGKGTGLGLSICHQIIVEKHGGQMDCISSLGKGAEFIIKIPLKFKVVGK

Sequences:

>Translated_458_residues
MLANQSVKNGHDLSLKLDSTLQELPVWDVEVEIHLPGNKLISFFEHEPLLPGVILTDNQKFVGMISRQRFFECMSRPYSF
GLFSMRPIESLYNFLQAQIFIFPAHKLVTETTQEALQRSPQFVYEPILVKSASGKHEVLDFHQLLLANSQIHALTLEKLQ
HVKKQSRIAKAGFRDLQNNYTQLLQNEKMAALGQLVAGIAHEVNNPINFIAGNLVHTIDYTQQLLNLINLYQHNYPHPVE
EITTAIAESELGFISHDLPNLLTSMRSGCDRIVQIIRSLRNFSRLDESDRKLVDIHEGIDSTLLILQSRLKNPNITHPIN
VIKEYENLPLVDCYAGLLNQVFMNLLSNAIDALEEAIVKYSGMVTKPQIIIRTEIIDDQQVVIRIADNGIGIPEEAKQRL
FDPFFTTKPVGKGTGLGLSICHQIIVEKHGGQMDCISSLGKGAEFIIKIPLKFKVVGK
>Mature_458_residues
MLANQSVKNGHDLSLKLDSTLQELPVWDVEVEIHLPGNKLISFFEHEPLLPGVILTDNQKFVGMISRQRFFECMSRPYSF
GLFSMRPIESLYNFLQAQIFIFPAHKLVTETTQEALQRSPQFVYEPILVKSASGKHEVLDFHQLLLANSQIHALTLEKLQ
HVKKQSRIAKAGFRDLQNNYTQLLQNEKMAALGQLVAGIAHEVNNPINFIAGNLVHTIDYTQQLLNLINLYQHNYPHPVE
EITTAIAESELGFISHDLPNLLTSMRSGCDRIVQIIRSLRNFSRLDESDRKLVDIHEGIDSTLLILQSRLKNPNITHPIN
VIKEYENLPLVDCYAGLLNQVFMNLLSNAIDALEEAIVKYSGMVTKPQIIIRTEIIDDQQVVIRIADNGIGIPEEAKQRL
FDPFFTTKPVGKGTGLGLSICHQIIVEKHGGQMDCISSLGKGAEFIIKIPLKFKVVGK

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=30.2583025830258, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=275, Percent_Identity=28, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=38.0165289256198, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51654; Mature: 51654

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANQSVKNGHDLSLKLDSTLQELPVWDVEVEIHLPGNKLISFFEHEPLLPGVILTDNQK
CCCCCCCCCCCCEEEEECHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCCCCEEEECCCH
FVGMISRQRFFECMSRPYSFGLFSMRPIESLYNFLQAQIFIFPAHKLVTETTQEALQRSP
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCC
QFVYEPILVKSASGKHEVLDFHQLLLANSQIHALTLEKLQHVKKQSRIAKAGFRDLQNNY
HHHHCCHHEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLLQNEKMAALGQLVAGIAHEVNNPINFIAGNLVHTIDYTQQLLNLINLYQHNYPHPVE
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EITTAIAESELGFISHDLPNLLTSMRSGCDRIVQIIRSLRNFSRLDESDRKLVDIHEGID
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCH
STLLILQSRLKNPNITHPINVIKEYENLPLVDCYAGLLNQVFMNLLSNAIDALEEAIVKY
HHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGMVTKPQIIIRTEIIDDQQVVIRIADNGIGIPEEAKQRLFDPFFTTKPVGKGTGLGLSI
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHH
CHQIIVEKHGGQMDCISSLGKGAEFIIKIPLKFKVVGK
HHHHHHHHCCCCCHHHHHCCCCCEEEEECCEEEEECCC
>Mature Secondary Structure
MLANQSVKNGHDLSLKLDSTLQELPVWDVEVEIHLPGNKLISFFEHEPLLPGVILTDNQK
CCCCCCCCCCCCEEEEECHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCCCCEEEECCCH
FVGMISRQRFFECMSRPYSFGLFSMRPIESLYNFLQAQIFIFPAHKLVTETTQEALQRSP
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCC
QFVYEPILVKSASGKHEVLDFHQLLLANSQIHALTLEKLQHVKKQSRIAKAGFRDLQNNY
HHHHCCHHEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLLQNEKMAALGQLVAGIAHEVNNPINFIAGNLVHTIDYTQQLLNLINLYQHNYPHPVE
HHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EITTAIAESELGFISHDLPNLLTSMRSGCDRIVQIIRSLRNFSRLDESDRKLVDIHEGID
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCH
STLLILQSRLKNPNITHPINVIKEYENLPLVDCYAGLLNQVFMNLLSNAIDALEEAIVKY
HHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGMVTKPQIIIRTEIIDDQQVVIRIADNGIGIPEEAKQRLFDPFFTTKPVGKGTGLGLSI
CCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHH
CHQIIVEKHGGQMDCISSLGKGAEFIIKIPLKFKVVGK
HHHHHHHHCCCCCHHHHHCCCCCEEEEECCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]