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The map label for this gene is dspA [H]

Identifier: 17231003

GI number: 17231003

Start: 4231592

End: 4233451

Strand: Direct

Name: dspA [H]

Synonym: alr3511

Alternate gene names: 17231003

Gene position: 4231592-4233451 (Clockwise)

Preceding gene: 17231002

Following gene: 17231004

Centisome position: 65.98

GC content: 45.0

Gene sequence:

>1860_bases
GTGGTTTCCTTGGTGATGAGTGGTCTCACCTTTTGGGCGGTAAACACAATTCAGCAAGATGCCCAAGTGAATGACACCCG
TTTTGGGCGGGATTTGGGTCTACTTCTGGCTGCTAACGTTGCACCCCTGGTTGCTGACCATAATCTGACTGAAGTTGCCC
AATTTTCCCAACGCTTCTACAGCAGCACTTCTAGTGTGCGCTATATGCTCTACGCTGATGAAACTGGGAAAATCTTTTTT
GGCATTCCCTTTTGGGAACCAGAGGTAGAAAACTCCCTCTCCATTGAGCGCCGGATACAACTACCAGAAGAGTACCCTGG
TGACGGCGAAAAGCCAATGGTACGGCAACACATGAGTCCAGATGGAATTGTGACTGATGTGTTCATTCCCCTAATTGTCG
ATAAAAAATACTTGGGTGTGTTGGCTATTGGCATCAACCCCAACCAAACAGCCGTTATCTCCACCAATTTCACCCGTGAT
GTTACCATTGCGGTTTTTATTACGATTTGGGTCATGGTGATTTTGGCAGGGGTGGTTAATGCTTTGACTATCACTAAGCC
CATTAAAGAATTATTGGTGGGGGTAAAACAAATCGCGGCTGGTAATTTTAAGCAGCGTATTGATTTGCCCTTGGGAGGCG
AACTAGGAGAGTTAATTCTCAATTTTAATGAAATGGCAGAGCGCCTAGAGCGCTATGAAGAGCAGAATATTGAGGAACTA
ACAGCCGAGAAAGCCAAGCTAGAAACCTTAGTTTCCACTATTGCCGACGGTGCTGTGTTGATTGACAACAATATGCAGGT
GATTTTAGTCAACCCCACAGCCAGACACATTTTTGGCTGGGAAGGTGCTGATGATGTGGTGGGTAGTAATGTGTTGCATC
ACCTACCCCCGGCGGTACAAATGGAAATCACCAGACCACTATACGAAATGGCAGCCGGTGAATGTGATAGCGCTGAATTT
CGCCTCACCCTCAACCAACCCAGCAACCGCACAATTCGCATTCTTTTGACTACAGTCCTCAATCTGCAACGGGAAAGCAT
CAAAGGTATTGCCATCACGGTGCAGGATATTACCCGTGAGGTGGAACTAAATGAAGCCAAAAGCCAATTTATCAGCAACG
TTTCCCACGAACTGCGAACGCCTTTATTTAATATCAAATCTTTTATTGAAACCCTCCATGACTACGGCGAAGACTTGAGT
TTAGAAGAACGCCAAGAGTTTCTGCAAACAGTTAATCATGAAACCGATCGCCTAACTCGTCTTGTTAATGATGTTTTAGA
TTTATCTAAGTTGGAATCTGGTCGTAGCTACAGTTTCGATGGTGTAGATTTAGCCCAGGCCATTGAACAAACACTACGTA
CCTATCAACTCAATGCTAGAGACAAAGGTATCGAACTCATCCAAGATGTTGCTCCTGGCTTGCCACTAGTCTTAGGGAAT
TACGATTTACTATTACAAGTCTTAGCTAATTTGGTCGGAAATGCCCTCAAATTCACTTCCTCCGGTGGCAAAATAGCCAT
TCGTACCTATGTATTAAACACTAAATCCAATTCCCCCAATCAGCCTGCCCAAGTGCGTATCGAAGTTTCTGACACCGGCA
TCGGTATTGCCCAGGAAGACCAACAGGCGATTTTTGACCGATTCTTCCGGGTAGAAAACAGAGTCCACACTTTAGAAGGC
ACAGGTTTAGGGTTGTCGATTGTGAGAAATATTGTGGAACGACACCGCAGTAGAGTAAATCTAGTTAGTGAAGTGGGAGT
GGGTACTACTTTTTGGTTTGACTTAATTTTGTTTGAGGACGAAGCACCAAAAAAGATGGTTGAATCTGGTGAGGAGAAGG
CAGCAATGCCGACTAGTTAG

Upstream 100 bases:

>100_bases
ATTAGAGATGCTGGCGCTGTTAAAAACAATTCGAGAAGCGATCGCCAATTGGTGGTCAGAGTTCACACTCCAGACTAAAC
TGTTAGCCGCAGCCACTTTG

Downstream 100 bases:

>100_bases
GAGGCTAATCAATTCAACATTCAAAAATTTTTAGACTCGGACATGGGATAGAAGAAAACTCAGCACTTTGCTATAAAATC
CTTTTGGGGAAATTGTATGC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MVSLVMSGLTFWAVNTIQQDAQVNDTRFGRDLGLLLAANVAPLVADHNLTEVAQFSQRFYSSTSSVRYMLYADETGKIFF
GIPFWEPEVENSLSIERRIQLPEEYPGDGEKPMVRQHMSPDGIVTDVFIPLIVDKKYLGVLAIGINPNQTAVISTNFTRD
VTIAVFITIWVMVILAGVVNALTITKPIKELLVGVKQIAAGNFKQRIDLPLGGELGELILNFNEMAERLERYEEQNIEEL
TAEKAKLETLVSTIADGAVLIDNNMQVILVNPTARHIFGWEGADDVVGSNVLHHLPPAVQMEITRPLYEMAAGECDSAEF
RLTLNQPSNRTIRILLTTVLNLQRESIKGIAITVQDITREVELNEAKSQFISNVSHELRTPLFNIKSFIETLHDYGEDLS
LEERQEFLQTVNHETDRLTRLVNDVLDLSKLESGRSYSFDGVDLAQAIEQTLRTYQLNARDKGIELIQDVAPGLPLVLGN
YDLLLQVLANLVGNALKFTSSGGKIAIRTYVLNTKSNSPNQPAQVRIEVSDTGIGIAQEDQQAIFDRFFRVENRVHTLEG
TGLGLSIVRNIVERHRSRVNLVSEVGVGTTFWFDLILFEDEAPKKMVESGEEKAAMPTS

Sequences:

>Translated_619_residues
MVSLVMSGLTFWAVNTIQQDAQVNDTRFGRDLGLLLAANVAPLVADHNLTEVAQFSQRFYSSTSSVRYMLYADETGKIFF
GIPFWEPEVENSLSIERRIQLPEEYPGDGEKPMVRQHMSPDGIVTDVFIPLIVDKKYLGVLAIGINPNQTAVISTNFTRD
VTIAVFITIWVMVILAGVVNALTITKPIKELLVGVKQIAAGNFKQRIDLPLGGELGELILNFNEMAERLERYEEQNIEEL
TAEKAKLETLVSTIADGAVLIDNNMQVILVNPTARHIFGWEGADDVVGSNVLHHLPPAVQMEITRPLYEMAAGECDSAEF
RLTLNQPSNRTIRILLTTVLNLQRESIKGIAITVQDITREVELNEAKSQFISNVSHELRTPLFNIKSFIETLHDYGEDLS
LEERQEFLQTVNHETDRLTRLVNDVLDLSKLESGRSYSFDGVDLAQAIEQTLRTYQLNARDKGIELIQDVAPGLPLVLGN
YDLLLQVLANLVGNALKFTSSGGKIAIRTYVLNTKSNSPNQPAQVRIEVSDTGIGIAQEDQQAIFDRFFRVENRVHTLEG
TGLGLSIVRNIVERHRSRVNLVSEVGVGTTFWFDLILFEDEAPKKMVESGEEKAAMPTS
>Mature_619_residues
MVSLVMSGLTFWAVNTIQQDAQVNDTRFGRDLGLLLAANVAPLVADHNLTEVAQFSQRFYSSTSSVRYMLYADETGKIFF
GIPFWEPEVENSLSIERRIQLPEEYPGDGEKPMVRQHMSPDGIVTDVFIPLIVDKKYLGVLAIGINPNQTAVISTNFTRD
VTIAVFITIWVMVILAGVVNALTITKPIKELLVGVKQIAAGNFKQRIDLPLGGELGELILNFNEMAERLERYEEQNIEEL
TAEKAKLETLVSTIADGAVLIDNNMQVILVNPTARHIFGWEGADDVVGSNVLHHLPPAVQMEITRPLYEMAAGECDSAEF
RLTLNQPSNRTIRILLTTVLNLQRESIKGIAITVQDITREVELNEAKSQFISNVSHELRTPLFNIKSFIETLHDYGEDLS
LEERQEFLQTVNHETDRLTRLVNDVLDLSKLESGRSYSFDGVDLAQAIEQTLRTYQLNARDKGIELIQDVAPGLPLVLGN
YDLLLQVLANLVGNALKFTSSGGKIAIRTYVLNTKSNSPNQPAQVRIEVSDTGIGIAQEDQQAIFDRFFRVENRVHTLEG
TGLGLSIVRNIVERHRSRVNLVSEVGVGTTFWFDLILFEDEAPKKMVESGEEKAAMPTS

Specific function: Member Of The Two-Component Regulatory System Phor/Phob Involved In The Phosphate Regulon Genes Expression. Phor May Function As A Membrane-Associated Protein Kinase That Phosphorylates Phob In Response To Environmental Signals. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=407, Percent_Identity=29.7297297297297, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789149, Length=258, Percent_Identity=34.1085271317829, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=34.5098039215686, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788549, Length=399, Percent_Identity=27.5689223057644, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=29.9145299145299, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=32.7731092436975, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI48994928, Length=473, Percent_Identity=26.4270613107822, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788393, Length=217, Percent_Identity=30.8755760368664, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=29.6153846153846, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=29.5081967213115, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=29.1845493562232, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790346, Length=217, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=27.9661016949153, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=355, Percent_Identity=24.7887323943662, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=28.8065843621399, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=26.5060240963855, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69021; Mature: 69021

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLVMSGLTFWAVNTIQQDAQVNDTRFGRDLGLLLAANVAPLVADHNLTEVAQFSQRFY
CHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH
SSTSSVRYMLYADETGKIFFGIPFWEPEVENSLSIERRIQLPEEYPGDGEKPMVRQHMSP
CCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHCCCC
DGIVTDVFIPLIVDKKYLGVLAIGINPNQTAVISTNFTRDVTIAVFITIWVMVILAGVVN
CCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ALTITKPIKELLVGVKQIAAGNFKQRIDLPLGGELGELILNFNEMAERLERYEEQNIEEL
HHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
TAEKAKLETLVSTIADGAVLIDNNMQVILVNPTARHIFGWEGADDVVGSNVLHHLPPAVQ
HHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCHHHEECCCCCCHHHHCHHHHHCCCHHH
MEITRPLYEMAAGECDSAEFRLTLNQPSNRTIRILLTTVLNLQRESIKGIAITVQDITRE
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHCCCEEEEEHHHHHHH
VELNEAKSQFISNVSHELRTPLFNIKSFIETLHDYGEDLSLEERQEFLQTVNHETDRLTR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHH
LVNDVLDLSKLESGRSYSFDGVDLAQAIEQTLRTYQLNARDKGIELIQDVAPGLPLVLGN
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCEEECC
YDLLLQVLANLVGNALKFTSSGGKIAIRTYVLNTKSNSPNQPAQVRIEVSDTGIGIAQED
HHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCHH
QQAIFDRFFRVENRVHTLEGTGLGLSIVRNIVERHRSRVNLVSEVGVGTTFWFDLILFED
HHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
EAPKKMVESGEEKAAMPTS
CCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVSLVMSGLTFWAVNTIQQDAQVNDTRFGRDLGLLLAANVAPLVADHNLTEVAQFSQRFY
CHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH
SSTSSVRYMLYADETGKIFFGIPFWEPEVENSLSIERRIQLPEEYPGDGEKPMVRQHMSP
CCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHCCCC
DGIVTDVFIPLIVDKKYLGVLAIGINPNQTAVISTNFTRDVTIAVFITIWVMVILAGVVN
CCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ALTITKPIKELLVGVKQIAAGNFKQRIDLPLGGELGELILNFNEMAERLERYEEQNIEEL
HHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
TAEKAKLETLVSTIADGAVLIDNNMQVILVNPTARHIFGWEGADDVVGSNVLHHLPPAVQ
HHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCHHHEECCCCCCHHHHCHHHHHCCCHHH
MEITRPLYEMAAGECDSAEFRLTLNQPSNRTIRILLTTVLNLQRESIKGIAITVQDITRE
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHCCCEEEEEHHHHHHH
VELNEAKSQFISNVSHELRTPLFNIKSFIETLHDYGEDLSLEERQEFLQTVNHETDRLTR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHH
LVNDVLDLSKLESGRSYSFDGVDLAQAIEQTLRTYQLNARDKGIELIQDVAPGLPLVLGN
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCCEEECC
YDLLLQVLANLVGNALKFTSSGGKIAIRTYVLNTKSNSPNQPAQVRIEVSDTGIGIAQED
HHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCHH
QQAIFDRFFRVENRVHTLEGTGLGLSIVRNIVERHRSRVNLVSEVGVGTTFWFDLILFED
HHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
EAPKKMVESGEEKAAMPTS
CCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]