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The map label for this gene is pntAB [H]

Identifier: 17230901

GI number: 17230901

Start: 4119752

End: 4120045

Strand: Reverse

Name: pntAB [H]

Synonym: asl3409

Alternate gene names: 17230901

Gene position: 4120045-4119752 (Counterclockwise)

Preceding gene: 17230902

Following gene: 17230900

Centisome position: 64.24

GC content: 40.82

Gene sequence:

>294_bases
ATGACAGAGGCATTACTTGCAGCTTTGTTTGTATTTGTGTTGGCATCATTCATTGGCTTTGAAGTCATTAACAAAATACC
GCCCACTCTCCATACACCATTAATGTCAGGCTCAAATGCCATTTCTGGTATTGCTGTGATTGGCGCAATATTAGCATCGG
GTGAAAGAAACACTAATTTATCCGTAATTCTAGGTTTGATTGCTGTGACTCTGGCAACAGTCAACGTTGTTGCTGGGTTT
CTCGTTACCGACAGAATGTTGCAAATGTTCAAGAAGAAGGAAGTTAAAGCGTGA

Upstream 100 bases:

>100_bases
TCGCAATCAACGCGTCAAGGATGCGTTACAAGCTTCGACTACTCAACTAGTTAGGGACTAGAGACTAGTCTCTAGCCTCT
CAATAATTAAGGAGTTTTAA

Downstream 100 bases:

>100_bases
GCGACTTTTTACCAACTGGAATACAGCTGACGTACTTAGTCGCTGCATCCTTATTTATTCTGGGTTTGAAAAAATTAGGT
TCCCCAGCTACAGCGCGTAA

Product: nicotinamide nucleotide transhydrogenase, subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MTEALLAALFVFVLASFIGFEVINKIPPTLHTPLMSGSNAISGIAVIGAILASGERNTNLSVILGLIAVTLATVNVVAGF
LVTDRMLQMFKKKEVKA

Sequences:

>Translated_97_residues
MTEALLAALFVFVLASFIGFEVINKIPPTLHTPLMSGSNAISGIAVIGAILASGERNTNLSVILGLIAVTLATVNVVAGF
LVTDRMLQMFKKKEVKA
>Mature_96_residues
TEALLAALFVFVLASFIGFEVINKIPPTLHTPLMSGSNAISGIAVIGAILASGERNTNLSVILGLIAVTLATVNVVAGFL
VTDRMLQMFKKKEVKA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=40.9638554216867, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=40.9638554216867, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787887, Length=90, Percent_Identity=45.5555555555556, Blast_Score=75, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17550456, Length=85, Percent_Identity=42.3529411764706, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10200; Mature: 10069

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEALLAALFVFVLASFIGFEVINKIPPTLHTPLMSGSNAISGIAVIGAILASGERNTNL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHH
SVILGLIAVTLATVNVVAGFLVTDRMLQMFKKKEVKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEALLAALFVFVLASFIGFEVINKIPPTLHTPLMSGSNAISGIAVIGAILASGERNTNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHH
SVILGLIAVTLATVNVVAGFLVTDRMLQMFKKKEVKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]