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The map label for this gene is fixL [H]

Identifier: 17230851

GI number: 17230851

Start: 4065023

End: 4066285

Strand: Reverse

Name: fixL [H]

Synonym: all3359

Alternate gene names: 17230851

Gene position: 4066285-4065023 (Counterclockwise)

Preceding gene: 17230852

Following gene: 17230846

Centisome position: 63.4

GC content: 38.64

Gene sequence:

>1263_bases
ATGTACACTTTTCAGGTGGAAGTTAGCCTGAATGGTGTAGAAGTAGCGAAGTATTTTGATAAATATCCCTTGTTACCAGG
GGTAATTTTGCTAGAACAAGGAAAGTTTACGGGGATGATGTCCCGGCGGCGATTGATAGAGTTTTTGATGCGTCCCTATG
GGCAAGATTTGTTTGCTAAAGAACCATTAGATGTTCTCTATCGTTATGCTCGTTTAGCAGTTTTAGTGCTGGCTGATACC
ACACCCATCTTGGCAGCCATGCAACATATATTAAGGCGATCGCCTGAATTTTTAGCAGAACCTCTAGTAGTACAAACAGC
AGACAATTCCTACAGATTGCTAGATCCCCATGAATTGAATATTGCAGCTTGGCAAATTCGTGGTATAGAAACTCAAGTAC
GCTACGAACGCAGCCAAGCCCAAATGATTCAAAACGATAAAATGGCCAGACTGGGTAGGCTAGTAGATGGAGTAGCACAC
GAAATTTTAGACCCTGTAGGTTTTATTTGGGGTAACTTAACTTATATCTCTAACTACAGCCAAGATTTACTGAAGTTAAT
AGCTGCTTATGATGAATGTCTATCTCCTGGTTGTGAGGAAATCAATGATATTAAAGAAGAAATTGAATTTGATTATCTAG
AAAAAGATTTATCTAAAGCATTAAATAGCGCTCGTTCCGGTGCGGAAAGACTAAAAAAACTCGTCACTAGCTTACAAAAC
TTTTGTCATATCGATGCAGTTTATCCTAAACCTGTAGATTTACACGCATCGATAGACAGTATTGTAATTTTAATTAAAAG
CCGTTTGAAAGGCGAAATCACTATTATTAAAAATTATGGAAAAATTCCCCCGGTCTCTTGTTTTATAGGACAGTTAAACC
AAGTATTGATGAATATTTTGAGTCACGCTGTTGATAGTTTGCTAGATGAAACTGTGCGACGGCAATTGCAACCAGATTCC
GGACAAAGTGTTAAGCAATCAAATATAGAAATTACAACGGAAGTTATTTCTCAAGCAGCTACCAGACCCAACGAACCTGA
TTCGCGCTGGGTTTCGATTTGTGTGGCTGATAATGGGACAGGAATGTCGGAGGAATTACAACAACAAATCCGCGAAAATT
TCTCTATAGAAAAAAGAACGGAAAAAGAAACAAGTTTAGCCGTTAGTTATCGCATTATCACAGCAAGACATGGCGGTAAA
CTCAATTTCTCTTCCAAACTAGGCATCGGTACAAAGTTTGAAATCCTACTACCTTTACTCTAG

Upstream 100 bases:

>100_bases
TCAAGTGTCACAAGAATTTTGTCCCCTTATATCACCACCTACTTTATCTAGAGGTAGCGATCGCGATTTATGTTTAGATT
CCACCATTCAAGAACTACCA

Downstream 100 bases:

>100_bases
TCAATAGTCAATAGTTATTTGTTTTTTTTCTCGTCACCCATTCACTTAACCGCCACTTGCTTCTCCCCAATCTCTGATGA
CAGAAAATAGGGCAGAATAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MYTFQVEVSLNGVEVAKYFDKYPLLPGVILLEQGKFTGMMSRRRLIEFLMRPYGQDLFAKEPLDVLYRYARLAVLVLADT
TPILAAMQHILRRSPEFLAEPLVVQTADNSYRLLDPHELNIAAWQIRGIETQVRYERSQAQMIQNDKMARLGRLVDGVAH
EILDPVGFIWGNLTYISNYSQDLLKLIAAYDECLSPGCEEINDIKEEIEFDYLEKDLSKALNSARSGAERLKKLVTSLQN
FCHIDAVYPKPVDLHASIDSIVILIKSRLKGEITIIKNYGKIPPVSCFIGQLNQVLMNILSHAVDSLLDETVRRQLQPDS
GQSVKQSNIEITTEVISQAATRPNEPDSRWVSICVADNGTGMSEELQQQIRENFSIEKRTEKETSLAVSYRIITARHGGK
LNFSSKLGIGTKFEILLPLL

Sequences:

>Translated_420_residues
MYTFQVEVSLNGVEVAKYFDKYPLLPGVILLEQGKFTGMMSRRRLIEFLMRPYGQDLFAKEPLDVLYRYARLAVLVLADT
TPILAAMQHILRRSPEFLAEPLVVQTADNSYRLLDPHELNIAAWQIRGIETQVRYERSQAQMIQNDKMARLGRLVDGVAH
EILDPVGFIWGNLTYISNYSQDLLKLIAAYDECLSPGCEEINDIKEEIEFDYLEKDLSKALNSARSGAERLKKLVTSLQN
FCHIDAVYPKPVDLHASIDSIVILIKSRLKGEITIIKNYGKIPPVSCFIGQLNQVLMNILSHAVDSLLDETVRRQLQPDS
GQSVKQSNIEITTEVISQAATRPNEPDSRWVSICVADNGTGMSEELQQQIRENFSIEKRTEKETSLAVSYRIITARHGGK
LNFSSKLGIGTKFEILLPLL
>Mature_420_residues
MYTFQVEVSLNGVEVAKYFDKYPLLPGVILLEQGKFTGMMSRRRLIEFLMRPYGQDLFAKEPLDVLYRYARLAVLVLADT
TPILAAMQHILRRSPEFLAEPLVVQTADNSYRLLDPHELNIAAWQIRGIETQVRYERSQAQMIQNDKMARLGRLVDGVAH
EILDPVGFIWGNLTYISNYSQDLLKLIAAYDECLSPGCEEINDIKEEIEFDYLEKDLSKALNSARSGAERLKKLVTSLQN
FCHIDAVYPKPVDLHASIDSIVILIKSRLKGEITIIKNYGKIPPVSCFIGQLNQVLMNILSHAVDSLLDETVRRQLQPDS
GQSVKQSNIEITTEVISQAATRPNEPDSRWVSICVADNGTGMSEELQQQIRENFSIEKRTEKETSLAVSYRIITARHGGK
LNFSSKLGIGTKFEILLPLL

Specific function: Putative oxygen sensor; modulates the activity of fixJ, a transcriptional activator of nitrogen fixation fixK gene. FixL probably acts as a kinase that phosphorylates fixJ [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47488; Mature: 47488

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTFQVEVSLNGVEVAKYFDKYPLLPGVILLEQGKFTGMMSRRRLIEFLMRPYGQDLFAK
CEEEEEEEEECHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHCC
EPLDVLYRYARLAVLVLADTTPILAAMQHILRRSPEFLAEPLVVQTADNSYRLLDPHELN
CCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCHHHHHCCEEEEECCCCEEECCCCCCC
IAAWQIRGIETQVRYERSQAQMIQNDKMARLGRLVDGVAHEILDPVGFIWGNLTYISNYS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QDLLKLIAAYDECLSPGCEEINDIKEEIEFDYLEKDLSKALNSARSGAERLKKLVTSLQN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCHIDAVYPKPVDLHASIDSIVILIKSRLKGEITIIKNYGKIPPVSCFIGQLNQVLMNIL
HHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
SHAVDSLLDETVRRQLQPDSGQSVKQSNIEITTEVISQAATRPNEPDSRWVSICVADNGT
HHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
GMSEELQQQIRENFSIEKRTEKETSLAVSYRIITARHGGKLNFSSKLGIGTKFEILLPLL
CCHHHHHHHHHHCCCCCHHCCHHHHHEEEEEEEEEECCCEECCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MYTFQVEVSLNGVEVAKYFDKYPLLPGVILLEQGKFTGMMSRRRLIEFLMRPYGQDLFAK
CEEEEEEEEECHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHCC
EPLDVLYRYARLAVLVLADTTPILAAMQHILRRSPEFLAEPLVVQTADNSYRLLDPHELN
CCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCHHHHHCCEEEEECCCCEEECCCCCCC
IAAWQIRGIETQVRYERSQAQMIQNDKMARLGRLVDGVAHEILDPVGFIWGNLTYISNYS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QDLLKLIAAYDECLSPGCEEINDIKEEIEFDYLEKDLSKALNSARSGAERLKKLVTSLQN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCHIDAVYPKPVDLHASIDSIVILIKSRLKGEITIIKNYGKIPPVSCFIGQLNQVLMNIL
HHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
SHAVDSLLDETVRRQLQPDSGQSVKQSNIEITTEVISQAATRPNEPDSRWVSICVADNGT
HHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
GMSEELQQQIRENFSIEKRTEKETSLAVSYRIITARHGGKLNFSSKLGIGTKFEILLPLL
CCHHHHHHHHHHCCCCCHHCCHHHHHEEEEEEEEEECCCEECCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2842062; 11481432; 8432704 [H]