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The map label for this gene is btuB [H]

Identifier: 17230802

GI number: 17230802

Start: 3991999

End: 3994095

Strand: Reverse

Name: btuB [H]

Synonym: all3310

Alternate gene names: 17230802

Gene position: 3994095-3991999 (Counterclockwise)

Preceding gene: 17230805

Following gene: 17230798

Centisome position: 62.27

GC content: 39.68

Gene sequence:

>2097_bases
GTGAGAAAGAGCTTTTTTTGGCTGCCTGTTGCTTTTCCTAGTTTATTTTTAGCATTTCCGGCTTTGGGTAGTGATACGGA
AATTACTCAAACAGTAGATAATTCTGATATTCCGTATTTGAGTGAAATTGAGTTACCCACCACCAGTGCTGAATTATTAA
CTCAATCGACACCAGGGGACTTAAATCCAGAGGGTGAACCTAGCGAACAGCCGGAAATTGAGGAAACTTCTAGTGACGAT
GCAGATATTACCATAGAAGCGATCGCCGAACCAGAAACCCTGCCAGCATCTACTCCCACTTACGTCATTGACCAAGAAGA
AATTCAAAAACAAGGTGCTACCAGTGTCGCTGATGTCTTAAAAAGAATGCCTGGTTTTGCCATTAATGATGTTGGTCATG
GTGCAGATATACACACAGGTACTTATTATCGGGGAGCCTCAATTAATCAGTCTGTATTTCTTATAAATGGCAGACGAATT
AACAATGATGTCAACACATATCATGGTGCAACTGACCTGAATAGCATTCCTGTAGAATCTATTGAGCGTGTCGAATTATC
TAGCGGTGTGACCTCTGCTTTATATGGTTCCTCCGCTTTTGGAGGAGTGGTTAATATCATCACCAAAAAAGGTTATCCAC
AACCTAAACTGACAAGTAGTTTAGAATTTGGCTCACTCAATCTCAATAATCAACAGTTTAGTTATAGTGGGGCAGTTGGT
GCGGCGACTTATAATTTTAGTTTTGAGCGGTACTTTGTTGATAACCGTTATCGTGTGCCTGTAGGTGCAGCAAATCGTGA
CTCCCAAGGGTTTTTATCAAATGCAGATACATCTACTAGCACCTATTTTGGCAATATTGGTTTAGATTTAGATCAAAGAA
ACTCTTTAAGTTTAGATATCACTAAACTCAGCAGTCGTAGAGGCTTAGTTTATTTCGGATTTCCCCTACAAAGAGATAGA
TTAGACCATGATGGTTTAAATATTGGTTTATCTTGGAAAACTCGCCTCGGTAATGGCAATAACTCTAACCTGACAACTAC
ATTTGGTTATAACCAAAATTATTTCAGCACCTACGGCCCTACAGTTTTTGCAGGTAGAGAATTTTATCGCACTGGTGTTT
TAGATACACAACAATTCACTGGTAGGATTGATCATGATTGGAGAATTTCTCCAAATAATAAGTTGCGTTGGGGACTAGAT
TTAAAAAATACTGATTTAAGTGGCGATGTTTTAAGCTCTAGTCCGAATCGGATTGCGTTTAACGAAACTGAAAATAGAAA
CGTATTAAATACAGCTTTATTTGCTGTGAATACATGGAATCTGAGTAATAGTTTTCAGTTAGATTTAGGACTGAGACAAA
GTTTTGATGGTCAGTTTGGCAATTATCTTAATCCTAGTGTGGGGCTACGTTACGACATCACACCATTAATTGCTATGCGT
GGTAGTTGGGCTGGAGGACAGCGCAACCCAGGTTTAGATCAGTTATATGTTTATGATACAGTTCATGGTTGGGAAGCAAA
CCCAGATTTAGAGCCGGAGACAGGTTCCTCTTGGACTGCGGGGGTAGATGTCAAGCTTGCTGATAATTTAACAGGGCAGT
TTACCTATTTTGGCAGCAGTCTGAATAATCGCTTAGGAATTGTGGCTGGAAGATGGGCAAATATTGGCTTAGTAGATACC
AATGGTTTAGAAGCCGCACTGCAATTAAAAGTTGCCGCTAACTGGTCAACTTTTCTCAACTACACTTATACAGATGCCCA
AATTAAGACAGGTTCAGAAAGAGGTTTACAGTTGGGAATGATTCCCTATTCTGTATTACAAACTGGCGTAGGTTATCAAA
ACTCAGGATGGCAGGCTAATTTGTATGTTACCTACAATAGTGGCGCTCGTAGAGCTTTTTTCACCCGACCAGGTGAGACA
ACTACCGATTTCGTCCCGTCTTTTGTCAATTTAGATTTGAGTGGTCGTATTCCCTTAACTCGTACTTTAGGACTAACAGT
TTACTTGGAAAATTTACTAGGTGAACAATATGAGCGAGTGAATCGAATTTATAGTCCTGGGTTTACTTTTCGCTTGGGTT
TAAGTTCGAGTATTTAA

Upstream 100 bases:

>100_bases
CAATAAACTAGGGGAAATACGACAGCGTGTCTTTTGACACAATTTTACAAAAAAAGTAACAATACCACTTAGTGATTGTT
ATTACTTGGTGTGAGACGAA

Downstream 100 bases:

>100_bases
CCTTTTTTGAATTCAAAATGCAAAATTCAAAATTCAAAATGAAGAATGGAAATAATTTTGAATTAATTCATTCTGGGTAC
AAGCCCCCGCCATAATCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRKSFFWLPVAFPSLFLAFPALGSDTEITQTVDNSDIPYLSEIELPTTSAELLTQSTPGDLNPEGEPSEQPEIEETSSDD
ADITIEAIAEPETLPASTPTYVIDQEEIQKQGATSVADVLKRMPGFAINDVGHGADIHTGTYYRGASINQSVFLINGRRI
NNDVNTYHGATDLNSIPVESIERVELSSGVTSALYGSSAFGGVVNIITKKGYPQPKLTSSLEFGSLNLNNQQFSYSGAVG
AATYNFSFERYFVDNRYRVPVGAANRDSQGFLSNADTSTSTYFGNIGLDLDQRNSLSLDITKLSSRRGLVYFGFPLQRDR
LDHDGLNIGLSWKTRLGNGNNSNLTTTFGYNQNYFSTYGPTVFAGREFYRTGVLDTQQFTGRIDHDWRISPNNKLRWGLD
LKNTDLSGDVLSSSPNRIAFNETENRNVLNTALFAVNTWNLSNSFQLDLGLRQSFDGQFGNYLNPSVGLRYDITPLIAMR
GSWAGGQRNPGLDQLYVYDTVHGWEANPDLEPETGSSWTAGVDVKLADNLTGQFTYFGSSLNNRLGIVAGRWANIGLVDT
NGLEAALQLKVAANWSTFLNYTYTDAQIKTGSERGLQLGMIPYSVLQTGVGYQNSGWQANLYVTYNSGARRAFFTRPGET
TTDFVPSFVNLDLSGRIPLTRTLGLTVYLENLLGEQYERVNRIYSPGFTFRLGLSSSI

Sequences:

>Translated_698_residues
MRKSFFWLPVAFPSLFLAFPALGSDTEITQTVDNSDIPYLSEIELPTTSAELLTQSTPGDLNPEGEPSEQPEIEETSSDD
ADITIEAIAEPETLPASTPTYVIDQEEIQKQGATSVADVLKRMPGFAINDVGHGADIHTGTYYRGASINQSVFLINGRRI
NNDVNTYHGATDLNSIPVESIERVELSSGVTSALYGSSAFGGVVNIITKKGYPQPKLTSSLEFGSLNLNNQQFSYSGAVG
AATYNFSFERYFVDNRYRVPVGAANRDSQGFLSNADTSTSTYFGNIGLDLDQRNSLSLDITKLSSRRGLVYFGFPLQRDR
LDHDGLNIGLSWKTRLGNGNNSNLTTTFGYNQNYFSTYGPTVFAGREFYRTGVLDTQQFTGRIDHDWRISPNNKLRWGLD
LKNTDLSGDVLSSSPNRIAFNETENRNVLNTALFAVNTWNLSNSFQLDLGLRQSFDGQFGNYLNPSVGLRYDITPLIAMR
GSWAGGQRNPGLDQLYVYDTVHGWEANPDLEPETGSSWTAGVDVKLADNLTGQFTYFGSSLNNRLGIVAGRWANIGLVDT
NGLEAALQLKVAANWSTFLNYTYTDAQIKTGSERGLQLGMIPYSVLQTGVGYQNSGWQANLYVTYNSGARRAFFTRPGET
TTDFVPSFVNLDLSGRIPLTRTLGLTVYLENLLGEQYERVNRIYSPGFTFRLGLSSSI
>Mature_698_residues
MRKSFFWLPVAFPSLFLAFPALGSDTEITQTVDNSDIPYLSEIELPTTSAELLTQSTPGDLNPEGEPSEQPEIEETSSDD
ADITIEAIAEPETLPASTPTYVIDQEEIQKQGATSVADVLKRMPGFAINDVGHGADIHTGTYYRGASINQSVFLINGRRI
NNDVNTYHGATDLNSIPVESIERVELSSGVTSALYGSSAFGGVVNIITKKGYPQPKLTSSLEFGSLNLNNQQFSYSGAVG
AATYNFSFERYFVDNRYRVPVGAANRDSQGFLSNADTSTSTYFGNIGLDLDQRNSLSLDITKLSSRRGLVYFGFPLQRDR
LDHDGLNIGLSWKTRLGNGNNSNLTTTFGYNQNYFSTYGPTVFAGREFYRTGVLDTQQFTGRIDHDWRISPNNKLRWGLD
LKNTDLSGDVLSSSPNRIAFNETENRNVLNTALFAVNTWNLSNSFQLDLGLRQSFDGQFGNYLNPSVGLRYDITPLIAMR
GSWAGGQRNPGLDQLYVYDTVHGWEANPDLEPETGSSWTAGVDVKLADNLTGQFTYFGSSLNNRLGIVAGRWANIGLVDT
NGLEAALQLKVAANWSTFLNYTYTDAQIKTGSERGLQLGMIPYSVLQTGVGYQNSGWQANLYVTYNSGARRAFFTRPGET
TTDFVPSFVNLDLSGRIPLTRTLGLTVYLENLLGEQYERVNRIYSPGFTFRLGLSSSI

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=117, Percent_Identity=44.4444444444444, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790405, Length=465, Percent_Identity=24.7311827956989, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76889; Mature: 76889

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSFFWLPVAFPSLFLAFPALGSDTEITQTVDNSDIPYLSEIELPTTSAELLTQSTPGD
CCCCEEEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHCCCCCCC
LNPEGEPSEQPEIEETSSDDADITIEAIAEPETLPASTPTYVIDQEEIQKQGATSVADVL
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHCCCHHHHHHH
KRMPGFAINDVGHGADIHTGTYYRGASINQSVFLINGRRINNDVNTYHGATDLNSIPVES
HHCCCCEEECCCCCCCCCCCCEEECCCCCCEEEEEECEEECCCCCCCCCCCCCCCCCHHH
IERVELSSGVTSALYGSSAFGGVVNIITKKGYPQPKLTSSLEFGSLNLNNQQFSYSGAVG
HHHHHHCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEEECEEECCCCEEEECCCEE
AATYNFSFERYFVDNRYRVPVGAANRDSQGFLSNADTSTSTYFGNIGLDLDQRNSLSLDI
EEEEECEEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
TKLSSRRGLVYFGFPLQRDRLDHDGLNIGLSWKTRLGNGNNSNLTTTFGYNQNYFSTYGP
EEECCCCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCC
TVFAGREFYRTGVLDTQQFTGRIDHDWRISPNNKLRWGLDLKNTDLSGDVLSSSPNRIAF
EEEECCHHHHCCCCCCHHHCCCCCCCEEECCCCCEEEEEEECCCCCCCCHHCCCCCEEEE
NETENRNVLNTALFAVNTWNLSNSFQLDLGLRQSFDGQFGNYLNPSVGLRYDITPLIAMR
CCCCCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCEEEEEC
GSWAGGQRNPGLDQLYVYDTVHGWEANPDLEPETGSSWTAGVDVKLADNLTGQFTYFGSS
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECEEEEEEECCCCEEEEEECCC
LNNRLGIVAGRWANIGLVDTNGLEAALQLKVAANWSTFLNYTYTDAQIKTGSERGLQLGM
CCCCEEEEEECCEEEEEEECCCCCEEEEEEEEECCCCEEEEEEECCEEECCCCCCCEEEC
IPYSVLQTGVGYQNSGWQANLYVTYNSGARRAFFTRPGETTTDFVPSFVNLDLSGRIPLT
CCHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCHHHCCHHEEEEECCCCCEE
RTLGLTVYLENLLGEQYERVNRIYSPGFTFRLGLSSSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure
MRKSFFWLPVAFPSLFLAFPALGSDTEITQTVDNSDIPYLSEIELPTTSAELLTQSTPGD
CCCCEEEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHCCCCCCC
LNPEGEPSEQPEIEETSSDDADITIEAIAEPETLPASTPTYVIDQEEIQKQGATSVADVL
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHCCCHHHHHHH
KRMPGFAINDVGHGADIHTGTYYRGASINQSVFLINGRRINNDVNTYHGATDLNSIPVES
HHCCCCEEECCCCCCCCCCCCEEECCCCCCEEEEEECEEECCCCCCCCCCCCCCCCCHHH
IERVELSSGVTSALYGSSAFGGVVNIITKKGYPQPKLTSSLEFGSLNLNNQQFSYSGAVG
HHHHHHCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCEEECEEECCCCEEEECCCEE
AATYNFSFERYFVDNRYRVPVGAANRDSQGFLSNADTSTSTYFGNIGLDLDQRNSLSLDI
EEEEECEEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
TKLSSRRGLVYFGFPLQRDRLDHDGLNIGLSWKTRLGNGNNSNLTTTFGYNQNYFSTYGP
EEECCCCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCC
TVFAGREFYRTGVLDTQQFTGRIDHDWRISPNNKLRWGLDLKNTDLSGDVLSSSPNRIAF
EEEECCHHHHCCCCCCHHHCCCCCCCEEECCCCCEEEEEEECCCCCCCCHHCCCCCEEEE
NETENRNVLNTALFAVNTWNLSNSFQLDLGLRQSFDGQFGNYLNPSVGLRYDITPLIAMR
CCCCCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCEEEEEC
GSWAGGQRNPGLDQLYVYDTVHGWEANPDLEPETGSSWTAGVDVKLADNLTGQFTYFGSS
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECEEEEEEECCCCEEEEEECCC
LNNRLGIVAGRWANIGLVDTNGLEAALQLKVAANWSTFLNYTYTDAQIKTGSERGLQLGM
CCCCEEEEEECCEEEEEEECCCCCEEEEEEEEECCCCEEEEEEECCEEECCCCCCCEEEC
IPYSVLQTGVGYQNSGWQANLYVTYNSGARRAFFTRPGETTTDFVPSFVNLDLSGRIPLT
CCHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCHHHCCHHEEEEECCCCCEE
RTLGLTVYLENLLGEQYERVNRIYSPGFTFRLGLSSSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]