Click here to switch to the map view.

The map label for this gene is phoP [H]

Identifier: 17230724

GI number: 17230724

Start: 3902261

End: 3903154

Strand: Reverse

Name: phoP [H]

Synonym: all3232

Alternate gene names: 17230724

Gene position: 3903154-3902261 (Counterclockwise)

Preceding gene: 17230728

Following gene: 17230719

Centisome position: 60.86

GC content: 41.95

Gene sequence:

>894_bases
ATGACCACCAATCTTAGTGATGGAAAAATGACAAACGAATCATCGAAAACAATCCTGGTTATTGAAGATGATAGCGATAG
TCGCAATCTCTTTTTAGCGGTGCTTGAGGCTAGAGGTTTTGATGGTATAGCAGCTGAAAACGGTGCGGCTGGTATTCAAC
AGGCACAAAAATATTTACCAGATTTGATTATCTGCGATATTATGATGCCTGATATGGATGGTTACGATGTTTTAAATGTG
CTACGCCAAGATCCTCTGACCGCGATTATTCCCTTTATTTTTCTCACTGGGAGCCATGAAAAAGGCGGTCTTCGCAAGGG
TATGGAGTTGGGAGCTGATGACTATATTACTAAGCCTTCTACTATAGAGGAAATACTCAAAGCGATCGCTATCCGTTTAG
AAAAGCAAGCTTTACTCAGGTATTGGTATGCAACTAAATCCCATCAACTTACCGAATCCCTCGCTGTAGACTCTGAAGCA
ATTTTTCCCTCTATTCCCCACCTTCAGGAAGTTTTTGATTATATAGAAGCTCATTATCATCAAGGAATTACATTATCAAA
TGTAGCTGTTGCGGTTGGTTATTCACCAGCTTATCTAACTAGTAGAGTTGCTAGAGAAACGGGGGATACGGTAAACGCCT
GGATTTTCAAGCGGCGAATGGCCGCAGCGCGTCCTCTACTAAGGAATACTAATAAAACCATCGAACAGATTGCGACAGCG
CTGGGTTATCAAAATGCTTGTCATTTCTCTCGCCAATTTCGCCAACATCACGGTTTACCTCCTAAAGCTTGGAGAAAACA
GCAACAATCGCTCCAGTCTGGTAGAAATCTGAAGCCACAACTGATTGATGTTTGTCCTCAATCGGAAAAATGCTTATTGA
CTAGCCGGAGTTAA

Upstream 100 bases:

>100_bases
CTGAAGCGTTGTACACCTGTTTAGGTGGTGATTTTTACCTTGCTTGAGGAAAGGACACCCAGTTTTTCTATATGGCTGAT
AGTTTCTATTGGTAACTGAA

Downstream 100 bases:

>100_bases
TTAGGACTTACGCACCCAGATTGTCTGTTGAGACCGGGTGTAAGGGTGTAGGGGTTTAAAACATTTATACCCTTTAATTA
CTTTTAGGTTTTATCAACTG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTTNLSDGKMTNESSKTILVIEDDSDSRNLFLAVLEARGFDGIAAENGAAGIQQAQKYLPDLIICDIMMPDMDGYDVLNV
LRQDPLTAIIPFIFLTGSHEKGGLRKGMELGADDYITKPSTIEEILKAIAIRLEKQALLRYWYATKSHQLTESLAVDSEA
IFPSIPHLQEVFDYIEAHYHQGITLSNVAVAVGYSPAYLTSRVARETGDTVNAWIFKRRMAAARPLLRNTNKTIEQIATA
LGYQNACHFSRQFRQHHGLPPKAWRKQQQSLQSGRNLKPQLIDVCPQSEKCLLTSRS

Sequences:

>Translated_297_residues
MTTNLSDGKMTNESSKTILVIEDDSDSRNLFLAVLEARGFDGIAAENGAAGIQQAQKYLPDLIICDIMMPDMDGYDVLNV
LRQDPLTAIIPFIFLTGSHEKGGLRKGMELGADDYITKPSTIEEILKAIAIRLEKQALLRYWYATKSHQLTESLAVDSEA
IFPSIPHLQEVFDYIEAHYHQGITLSNVAVAVGYSPAYLTSRVARETGDTVNAWIFKRRMAAARPLLRNTNKTIEQIATA
LGYQNACHFSRQFRQHHGLPPKAWRKQQQSLQSGRNLKPQLIDVCPQSEKCLLTSRS
>Mature_296_residues
TTNLSDGKMTNESSKTILVIEDDSDSRNLFLAVLEARGFDGIAAENGAAGIQQAQKYLPDLIICDIMMPDMDGYDVLNVL
RQDPLTAIIPFIFLTGSHEKGGLRKGMELGADDYITKPSTIEEILKAIAIRLEKQALLRYWYATKSHQLTESLAVDSEAI
FPSIPHLQEVFDYIEAHYHQGITLSNVAVAVGYSPAYLTSRVARETGDTVNAWIFKRRMAAARPLLRNTNKTIEQIATAL
GYQNACHFSRQFRQHHGLPPKAWRKQQQSLQSGRNLKPQLIDVCPQSEKCLLTSRS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=127, Percent_Identity=35.4330708661417, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790863, Length=108, Percent_Identity=37.037037037037, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=35, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790860, Length=120, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786911, Length=128, Percent_Identity=32.03125, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788394, Length=124, Percent_Identity=28.2258064516129, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082012, Length=141, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 33207; Mature: 33076

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNLSDGKMTNESSKTILVIEDDSDSRNLFLAVLEARGFDGIAAENGAAGIQQAQKYLP
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCC
DLIICDIMMPDMDGYDVLNVLRQDPLTAIIPFIFLTGSHEKGGLRKGMELGADDYITKPS
HHEEHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHCCCCCCCCCCH
TIEEILKAIAIRLEKQALLRYWYATKSHQLTESLAVDSEAIFPSIPHLQEVFDYIEAHYH
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHH
QGITLSNVAVAVGYSPAYLTSRVARETGDTVNAWIFKRRMAAARPLLRNTNKTIEQIATA
CCCEEHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LGYQNACHFSRQFRQHHGLPPKAWRKQQQSLQSGRNLKPQLIDVCPQSEKCLLTSRS
HCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEECCC
>Mature Secondary Structure 
TTNLSDGKMTNESSKTILVIEDDSDSRNLFLAVLEARGFDGIAAENGAAGIQQAQKYLP
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCC
DLIICDIMMPDMDGYDVLNVLRQDPLTAIIPFIFLTGSHEKGGLRKGMELGADDYITKPS
HHEEHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHCCCCCCCCCCH
TIEEILKAIAIRLEKQALLRYWYATKSHQLTESLAVDSEAIFPSIPHLQEVFDYIEAHYH
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHH
QGITLSNVAVAVGYSPAYLTSRVARETGDTVNAWIFKRRMAAARPLLRNTNKTIEQIATA
CCCEEHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LGYQNACHFSRQFRQHHGLPPKAWRKQQQSLQSGRNLKPQLIDVCPQSEKCLLTSRS
HCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]