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The map label for this gene is pkn1 [H]

Identifier: 17230718

GI number: 17230718

Start: 3896360

End: 3898192

Strand: Reverse

Name: pkn1 [H]

Synonym: all3226

Alternate gene names: 17230718

Gene position: 3898192-3896360 (Counterclockwise)

Preceding gene: 17230719

Following gene: 17230715

Centisome position: 60.78

GC content: 43.81

Gene sequence:

>1833_bases
ATGGCGAAAAATTGGGCGATCGCGATCGGCGTTAACCAGTATGATTATCTGGAACCGCTAAACTATGCCAAGCGGGATGC
AGAGTTAATCCAGCAGTTTCTCATTAAAGAGGCGGGGTTTGACCAAGTTATTTTATTCAGTGATGATTCCCCTAATTTTG
GGGTTAGCTCAACCCGCCCTACCCGTACTCACTTACGGCGAGTGTTACTAACTTTATTTGAAAGCCTCTCAATGGGTGCG
GGTGATAACTTTTGGTTTTTCTTCAGTGGTCATGGGATGCGCCATAATGGACGCGATTATCTCATGCCTTCAGATGGTAA
TCCCAGGGACATTGCAGATACGGCCATTTCCATTAACTTTGTCACTGAAAACCTGCGTTGCTCTGGTGCTGATAATCTTG
TCTTGATTTTAGATGCTTGTCGCAATGAAGGCAAAATAGATGGTATAAAAGGTGGTCATATTGGTATTGGCCAAGAAACC
TCAGCAGAAGCACGTCAAAAAGGGGTTATTAGTATTTTTTCCTGTAGTCCGCAGGAATATTCTTATGAAATTGAAGCATT
ACAACAAGGTGCTTTTACTACTGCATTATTAGAAGGGTTTCGAGATGGATACACCACAGCTGCAAGCTTGAATCAGTATC
TACAACGTCGTGTCTCGGAAATTGTTAGCTCCCACAGTAAAGGCAAACAAACACCTTATATTATTGCCGAGCCTGTAACT
AAATCTCATTTAATACTTGTACCTCGATATGCAACCCCAGCCGATATTGCTACCCTTAGAGAAGATGCTTACGAAGCAGA
AGTAAACAGAAATTGGGATTTGGCAGAACAATTATGGATGCGGGTTTTAACTGCTGATTCAACGCAGACTACGAAAGCAA
TCGAGGCAATTAAGAGAATTGTCCTTTTGCGTGGTAAAACCCTAGTAAAACAAGAAGGACAAACTGATGATCCTCCTAAG
GGAGTATCTACACCTGAAAAAAATCTCTTAGAGACCTTTTCATTTGAAGTGGTGACGGTAAACGCACAAGGGAAAATCAC
CAACCGCCAAAACCGGACAGCAAAATATTTTGCAGAAGACTTAGGGAATGGTGTCACCTTGGAAATGGTGCAGATACCAG
GGGGAACATTTACAATGGGTTCACCGGAAAGCGAGGCGGAAAGATTTGATAGGGAAAGTCCCCAGCGTCAGGTGACAGTT
CCCGGCTTCTTCATGGGGAAATATGCAGTTACCCAAGCACAGTATCAAGCAGTTATGGGTGGCAACATTCTTCAAAAGAT
TATAGGCAATAAAAATAATCCTTCCTACTTCAAAGGTGAGAAAAGACCTGTAGAACAAGTGAGTTGGAATGATGCGGTAG
AGTTTTGTCAGAAATTGAGCCAGAAGACAGGAAGAACCTACCGATTACCCAGCGAGGCAGAATGGGAATATGCTTGTCGT
GCGGGGACAACCACGCCCTTTTATTTTGGCGAAACCATCACCACAGATTTAGTTAACTACAACGGTGAATTTCCCTACGG
TGCTGCACCCAAAGGTAAATATCGTGGAGAAACAACCAATGTAGGAATATTTCCGCCGAACTCTTTCGGTTTATACGATA
TGTGTGGTAATGTATGGGAATGGTGCGAAGATATATATAATGATAATTACCAAGGTGCGCCAACAGATGGAAGTGCGTTG
CTTACTAGTAAAAATAATAACATAAAGCTGGTGCGTGGCGGTTCGTGGCACAGCCATGCCAGGAGCTGTCGCTGTGCTTA
TCGCGACATGCACGCGCGCGCGTATCGGCTCTTCAATGTTGGTTTTCGTGTTGTCGCGGTGGCTATTCTGTGA

Upstream 100 bases:

>100_bases
ATTAGCGGCGAAGGTGAAGTCAAGTTAATTGGGAACGGCGCGAAAGCTGGTGGTAAAGGTGCAATTAAACTGACATTTAG
GCGACAAGAACCAAAGTAGG

Downstream 100 bases:

>100_bases
GGATTCCTTTCCCTTTTCTCTCTTGCCCTTTTCCCCTTTACACTTCTTAATCTTTACACTTTGTTAGTGTAGCGAAGCGG
AACGATCTTTTTTTTAAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MAKNWAIAIGVNQYDYLEPLNYAKRDAELIQQFLIKEAGFDQVILFSDDSPNFGVSSTRPTRTHLRRVLLTLFESLSMGA
GDNFWFFFSGHGMRHNGRDYLMPSDGNPRDIADTAISINFVTENLRCSGADNLVLILDACRNEGKIDGIKGGHIGIGQET
SAEARQKGVISIFSCSPQEYSYEIEALQQGAFTTALLEGFRDGYTTAASLNQYLQRRVSEIVSSHSKGKQTPYIIAEPVT
KSHLILVPRYATPADIATLREDAYEAEVNRNWDLAEQLWMRVLTADSTQTTKAIEAIKRIVLLRGKTLVKQEGQTDDPPK
GVSTPEKNLLETFSFEVVTVNAQGKITNRQNRTAKYFAEDLGNGVTLEMVQIPGGTFTMGSPESEAERFDRESPQRQVTV
PGFFMGKYAVTQAQYQAVMGGNILQKIIGNKNNPSYFKGEKRPVEQVSWNDAVEFCQKLSQKTGRTYRLPSEAEWEYACR
AGTTTPFYFGETITTDLVNYNGEFPYGAAPKGKYRGETTNVGIFPPNSFGLYDMCGNVWEWCEDIYNDNYQGAPTDGSAL
LTSKNNNIKLVRGGSWHSHARSCRCAYRDMHARAYRLFNVGFRVVAVAIL

Sequences:

>Translated_610_residues
MAKNWAIAIGVNQYDYLEPLNYAKRDAELIQQFLIKEAGFDQVILFSDDSPNFGVSSTRPTRTHLRRVLLTLFESLSMGA
GDNFWFFFSGHGMRHNGRDYLMPSDGNPRDIADTAISINFVTENLRCSGADNLVLILDACRNEGKIDGIKGGHIGIGQET
SAEARQKGVISIFSCSPQEYSYEIEALQQGAFTTALLEGFRDGYTTAASLNQYLQRRVSEIVSSHSKGKQTPYIIAEPVT
KSHLILVPRYATPADIATLREDAYEAEVNRNWDLAEQLWMRVLTADSTQTTKAIEAIKRIVLLRGKTLVKQEGQTDDPPK
GVSTPEKNLLETFSFEVVTVNAQGKITNRQNRTAKYFAEDLGNGVTLEMVQIPGGTFTMGSPESEAERFDRESPQRQVTV
PGFFMGKYAVTQAQYQAVMGGNILQKIIGNKNNPSYFKGEKRPVEQVSWNDAVEFCQKLSQKTGRTYRLPSEAEWEYACR
AGTTTPFYFGETITTDLVNYNGEFPYGAAPKGKYRGETTNVGIFPPNSFGLYDMCGNVWEWCEDIYNDNYQGAPTDGSAL
LTSKNNNIKLVRGGSWHSHARSCRCAYRDMHARAYRLFNVGFRVVAVAIL
>Mature_609_residues
AKNWAIAIGVNQYDYLEPLNYAKRDAELIQQFLIKEAGFDQVILFSDDSPNFGVSSTRPTRTHLRRVLLTLFESLSMGAG
DNFWFFFSGHGMRHNGRDYLMPSDGNPRDIADTAISINFVTENLRCSGADNLVLILDACRNEGKIDGIKGGHIGIGQETS
AEARQKGVISIFSCSPQEYSYEIEALQQGAFTTALLEGFRDGYTTAASLNQYLQRRVSEIVSSHSKGKQTPYIIAEPVTK
SHLILVPRYATPADIATLREDAYEAEVNRNWDLAEQLWMRVLTADSTQTTKAIEAIKRIVLLRGKTLVKQEGQTDDPPKG
VSTPEKNLLETFSFEVVTVNAQGKITNRQNRTAKYFAEDLGNGVTLEMVQIPGGTFTMGSPESEAERFDRESPQRQVTVP
GFFMGKYAVTQAQYQAVMGGNILQKIIGNKNNPSYFKGEKRPVEQVSWNDAVEFCQKLSQKTGRTYRLPSEAEWEYACRA
GTTTPFYFGETITTDLVNYNGEFPYGAAPKGKYRGETTNVGIFPPNSFGLYDMCGNVWEWCEDIYNDNYQGAPTDGSALL
TSKNNNIKLVRGGSWHSHARSCRCAYRDMHARAYRLFNVGFRVVAVAIL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG4249

COG function: function code R; Uncharacterized protein containing caspase domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=263, Percent_Identity=32.319391634981, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI38202250, Length=288, Percent_Identity=29.8611111111111, Blast_Score=113, Evalue=7e-25,
Organism=Homo sapiens, GI257470977, Length=285, Percent_Identity=28.4210526315789, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI194248087, Length=284, Percent_Identity=31.6901408450704, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI194248088, Length=299, Percent_Identity=30.1003344481605, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226437577, Length=176, Percent_Identity=33.5227272727273, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130397, Length=329, Percent_Identity=27.355623100304, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 68159; Mature: 68028

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNWAIAIGVNQYDYLEPLNYAKRDAELIQQFLIKEAGFDQVILFSDDSPNFGVSSTRP
CCCCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
TRTHLRRVLLTLFESLSMGAGDNFWFFFSGHGMRHNGRDYLMPSDGNPRDIADTAISINF
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHEEEEEE
VTENLRCSGADNLVLILDACRNEGKIDGIKGGHIGIGQETSAEARQKGVISIFSCSPQEY
EECCCEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCHHH
SYEIEALQQGAFTTALLEGFRDGYTTAASLNQYLQRRVSEIVSSHSKGKQTPYIIAEPVT
HHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCC
KSHLILVPRYATPADIATLREDAYEAEVNRNWDLAEQLWMRVLTADSTQTTKAIEAIKRI
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
VLLRGKTLVKQEGQTDDPPKGVSTPEKNLLETFSFEVVTVNAQGKITNRQNRTAKYFAED
HHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHH
LGNGVTLEMVQIPGGTFTMGSPESEAERFDRESPQRQVTVPGFFMGKYAVTQAQYQAVMG
HCCCEEEEEEEECCCEEECCCCHHHHHHHHCCCCCCEEECCCEECCHHHHHHHHHHHHHC
GNILQKIIGNKNNPSYFKGEKRPVEQVSWNDAVEFCQKLSQKTGRTYRLPSEAEWEYACR
HHHHHHHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
AGTTTPFYFGETITTDLVNYNGEFPYGAAPKGKYRGETTNVGIFPPNSFGLYDMCGNVWE
CCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
WCEDIYNDNYQGAPTDGSALLTSKNNNIKLVRGGSWHSHARSCRCAYRDMHARAYRLFNV
HHHHHHCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GFRVVAVAIL
CHHHEEEEEC
>Mature Secondary Structure 
AKNWAIAIGVNQYDYLEPLNYAKRDAELIQQFLIKEAGFDQVILFSDDSPNFGVSSTRP
CCCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
TRTHLRRVLLTLFESLSMGAGDNFWFFFSGHGMRHNGRDYLMPSDGNPRDIADTAISINF
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHEEEEEE
VTENLRCSGADNLVLILDACRNEGKIDGIKGGHIGIGQETSAEARQKGVISIFSCSPQEY
EECCCEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCHHH
SYEIEALQQGAFTTALLEGFRDGYTTAASLNQYLQRRVSEIVSSHSKGKQTPYIIAEPVT
HHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCC
KSHLILVPRYATPADIATLREDAYEAEVNRNWDLAEQLWMRVLTADSTQTTKAIEAIKRI
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
VLLRGKTLVKQEGQTDDPPKGVSTPEKNLLETFSFEVVTVNAQGKITNRQNRTAKYFAED
HHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHH
LGNGVTLEMVQIPGGTFTMGSPESEAERFDRESPQRQVTVPGFFMGKYAVTQAQYQAVMG
HCCCEEEEEEEECCCEEECCCCHHHHHHHHCCCCCCEEECCCEECCHHHHHHHHHHHHHC
GNILQKIIGNKNNPSYFKGEKRPVEQVSWNDAVEFCQKLSQKTGRTYRLPSEAEWEYACR
HHHHHHHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCC
AGTTTPFYFGETITTDLVNYNGEFPYGAAPKGKYRGETTNVGIFPPNSFGLYDMCGNVWE
CCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
WCEDIYNDNYQGAPTDGSALLTSKNNNIKLVRGGSWHSHARSCRCAYRDMHARAYRLFNV
HHHHHHCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GFRVVAVAIL
CHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]