Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 17230636

GI number: 17230636

Start: 3805461

End: 3806780

Strand: Reverse

Name: mdtA [H]

Synonym: all3144

Alternate gene names: 17230636

Gene position: 3806780-3805461 (Counterclockwise)

Preceding gene: 17230637

Following gene: 17230635

Centisome position: 59.35

GC content: 47.35

Gene sequence:

>1320_bases
ATGTCATCCTCTGAGCCTCAAACTGATTTTAGAGATAATCTTCCCCAGGAACCCCCTGAGCCACCACCAAAACAACGGCG
GTGGCTCAGGTTATTGTTGGCTGCCATCCTCTTATTAGGGGGTGGAACAGCGATAGTTTGGCGGTTACTGACTCCGAGCG
ATCGCCCACCCGCCACTGCTGAGGCTCAACCGCCAGGCGTAAGAGTAAAAACATCACCAGTACAAGTCGGCACTATTGAA
GAAAGCACAGATTTTGTGGCTAGCTTAGAGTCACGGCGTTCCGTCACTCTCCAACCAAGAGTACAGGGTCAAGTGACCCA
GATATTTGTGAGATCGGGAGATGCGATCGCCTCTGGTGCAGCCGTGATTCAAATCGACCCCAGACAGCAACAAGCAGCCG
TTATCAGTAACGATGCAGCCACCCAAGCTAGCAAAGCACAGCTAGAAAACGCTAATGCTACCCTCAAATCCTTAGAAGCG
GAAAGATTATCTAATGTTGCTGATGTGCGATTGAATCAGCAAGAGTACGACAGGTATGCTTCTTTAGCTGACCAAGGGGC
TGTATCTCGGCAAACCAAAGATCAGTATGCCAACAGACTAGCTACAGCACGAGCCAATCTCAACGCCATAGAATCTAGGA
TTCAAGCCCAAAAAGCTAGTATCGCCCAAGCACAAAAATCAGTGCAGCAAGCCCAGGCTAATACTGACGAGCAACAAGTC
CAACTCCAGTTCTATCGAATTACTGCCCCCTTTGAAGGCACTGTCGGCAATATCCCCGTTAAAATTGGTGATTTTGTCAA
TAGTTCCACACCACTACTAACCATTACTCAAAACCGACCCTTGGAGGTTAATATCTCTGTACCTCTAGAACGAGGGCCCC
AATTACGTCAGGGAATGCCTGTAGAGATTATGAACACCCAAGGTCAAACACTGGGTACTAGTAGGGTATTTTTCATTGCT
CCTAATGCCAGTAACGAAACCCAATCAATTCTGGTAAAAGCCTTATATAACAACTCAAATGGTCAACTAAGGGCAGATCA
GCTAGTGAGAGCTAGAGTTATTTGGAATCAACGTACAGGCGTTTTAATTCCGATTACAGCAGTCACACGCATCGCCGGGG
AAACTTTTGTCTATGTAACCCAAACGGAAAAAACGCCCCAAGGAACCTCCCAACTAGTTGCACGGCAAAAACGCGTGCAG
TTGGGTGATATCAGAGGGAATAATTACCAAATCATCAAGGGATTACAGCCAACAGACACAATTGTCACCTCAGGGCTGCT
GAATCTCCGTGATGGCGTTCCTATTGTTCCTGAATCTTAG

Upstream 100 bases:

>100_bases
CTATTTATGGAGACTCATGCTAAATAAGTAAATTCCATGGCCTACATATTTATCCTTGTGACAATGTTTAGTTAATTAGT
TCTTAGGTTCGCTGTAAACC

Downstream 100 bases:

>100_bases
TGTCGGGGACTAGGTACTAGGTACTGGGAGAAGAAGATAAATCTTACTTCCAATCCCTAATCCCTAATCCCTAATCCCCA
TTCCCTAATCCCTAATCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSSSEPQTDFRDNLPQEPPEPPPKQRRWLRLLLAAILLLGGGTAIVWRLLTPSDRPPATAEAQPPGVRVKTSPVQVGTIE
ESTDFVASLESRRSVTLQPRVQGQVTQIFVRSGDAIASGAAVIQIDPRQQQAAVISNDAATQASKAQLENANATLKSLEA
ERLSNVADVRLNQQEYDRYASLADQGAVSRQTKDQYANRLATARANLNAIESRIQAQKASIAQAQKSVQQAQANTDEQQV
QLQFYRITAPFEGTVGNIPVKIGDFVNSSTPLLTITQNRPLEVNISVPLERGPQLRQGMPVEIMNTQGQTLGTSRVFFIA
PNASNETQSILVKALYNNSNGQLRADQLVRARVIWNQRTGVLIPITAVTRIAGETFVYVTQTEKTPQGTSQLVARQKRVQ
LGDIRGNNYQIIKGLQPTDTIVTSGLLNLRDGVPIVPES

Sequences:

>Translated_439_residues
MSSSEPQTDFRDNLPQEPPEPPPKQRRWLRLLLAAILLLGGGTAIVWRLLTPSDRPPATAEAQPPGVRVKTSPVQVGTIE
ESTDFVASLESRRSVTLQPRVQGQVTQIFVRSGDAIASGAAVIQIDPRQQQAAVISNDAATQASKAQLENANATLKSLEA
ERLSNVADVRLNQQEYDRYASLADQGAVSRQTKDQYANRLATARANLNAIESRIQAQKASIAQAQKSVQQAQANTDEQQV
QLQFYRITAPFEGTVGNIPVKIGDFVNSSTPLLTITQNRPLEVNISVPLERGPQLRQGMPVEIMNTQGQTLGTSRVFFIA
PNASNETQSILVKALYNNSNGQLRADQLVRARVIWNQRTGVLIPITAVTRIAGETFVYVTQTEKTPQGTSQLVARQKRVQ
LGDIRGNNYQIIKGLQPTDTIVTSGLLNLRDGVPIVPES
>Mature_438_residues
SSSEPQTDFRDNLPQEPPEPPPKQRRWLRLLLAAILLLGGGTAIVWRLLTPSDRPPATAEAQPPGVRVKTSPVQVGTIEE
STDFVASLESRRSVTLQPRVQGQVTQIFVRSGDAIASGAAVIQIDPRQQQAAVISNDAATQASKAQLENANATLKSLEAE
RLSNVADVRLNQQEYDRYASLADQGAVSRQTKDQYANRLATARANLNAIESRIQAQKASIAQAQKSVQQAQANTDEQQVQ
LQFYRITAPFEGTVGNIPVKIGDFVNSSTPLLTITQNRPLEVNISVPLERGPQLRQGMPVEIMNTQGQTLGTSRVFFIAP
NASNETQSILVKALYNNSNGQLRADQLVRARVIWNQRTGVLIPITAVTRIAGETFVYVTQTEKTPQGTSQLVARQKRVQL
GDIRGNNYQIIKGLQPTDTIVTSGLLNLRDGVPIVPES

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=403, Percent_Identity=26.0545905707196, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789929, Length=426, Percent_Identity=25.3521126760563, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081796, Length=396, Percent_Identity=23.2323232323232, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47919; Mature: 47788

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSEPQTDFRDNLPQEPPEPPPKQRRWLRLLLAAILLLGGGTAIVWRLLTPSDRPPATA
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCC
EAQPPGVRVKTSPVQVGTIEESTDFVASLESRRSVTLQPRVQGQVTQIFVRSGDAIASGA
CCCCCCEEEEECCEEEEECCCHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCHHCCE
AVIQIDPRQQQAAVISNDAATQASKAQLENANATLKSLEAERLSNVADVRLNQQEYDRYA
EEEEECCCCHHHHEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHEEECHHHHHHHH
SLADQGAVSRQTKDQYANRLATARANLNAIESRIQAQKASIAQAQKSVQQAQANTDEQQV
HHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
QLQFYRITAPFEGTVGNIPVKIGDFVNSSTPLLTITQNRPLEVNISVPLERGPQLRQGMP
EEEEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEEECCCCCCCHHHCCCC
VEIMNTQGQTLGTSRVFFIAPNASNETQSILVKALYNNSNGQLRADQLVRARVIWNQRTG
EEEECCCCCCCCCCEEEEEECCCCCHHHHHEEEEEEECCCCCEEHHHHHEEHEEECCCCC
VLIPITAVTRIAGETFVYVTQTEKTPQGTSQLVARQKRVQLGDIRGNNYQIIKGLQPTDT
EEEEHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCEEECCCCCCEEEEECCCCHHH
IVTSGLLNLRDGVPIVPES
HHHHCHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSSEPQTDFRDNLPQEPPEPPPKQRRWLRLLLAAILLLGGGTAIVWRLLTPSDRPPATA
CCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCCC
EAQPPGVRVKTSPVQVGTIEESTDFVASLESRRSVTLQPRVQGQVTQIFVRSGDAIASGA
CCCCCCEEEEECCEEEEECCCHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCHHCCE
AVIQIDPRQQQAAVISNDAATQASKAQLENANATLKSLEAERLSNVADVRLNQQEYDRYA
EEEEECCCCHHHHEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHEEECHHHHHHHH
SLADQGAVSRQTKDQYANRLATARANLNAIESRIQAQKASIAQAQKSVQQAQANTDEQQV
HHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
QLQFYRITAPFEGTVGNIPVKIGDFVNSSTPLLTITQNRPLEVNISVPLERGPQLRQGMP
EEEEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEEEECCCCCCCHHHCCCC
VEIMNTQGQTLGTSRVFFIAPNASNETQSILVKALYNNSNGQLRADQLVRARVIWNQRTG
EEEECCCCCCCCCCEEEEEECCCCCHHHHHEEEEEEECCCCCEEHHHHHEEHEEECCCCC
VLIPITAVTRIAGETFVYVTQTEKTPQGTSQLVARQKRVQLGDIRGNNYQIIKGLQPTDT
EEEEHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCEEECCCCCCEEEEECCCCHHH
IVTSGLLNLRDGVPIVPES
HHHHCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA