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The map label for this gene is qorA [H]

Identifier: 17230440

GI number: 17230440

Start: 3586169

End: 3587176

Strand: Direct

Name: qorA [H]

Synonym: alr2948

Alternate gene names: 17230440

Gene position: 3586169-3587176 (Clockwise)

Preceding gene: 17230439

Following gene: 17230441

Centisome position: 55.91

GC content: 44.15

Gene sequence:

>1008_bases
GTGAAAGCCGTTCTGATGACCGCACCGGGGAATCCTGAAGTACTGCAATTGCAGGAAGTACCCAATCCTGGCGTTCCTGT
AGGTAGTACAGAACTTTTAGTTCGTTTGGTAGCGGCTGGTATTAACCCCATTGATACTAAACTACGCAAGCGTGGCACTT
TTTACCCTGAGCAAATGCCTGCCATTTTAGGATGTGATGGTGCTGGTGTTGTAGAAGCTGTGGGTGCTGGTGTCCAGGGT
TTTCGTGTGGGGGATGCAGTGTATTTTTGCAATGGTGGTTTAGGAGGACATCAAGGCAATTACGCTGAATATACTATTGT
CGATGAACGTTTTGCTGCCCATAAGCCAGCTTCCCTGACCTTTGCTGAAGCCGCCGCCGCACCTTTGGTACTAATCACCG
CTTGGGAAGCTTTATATGAACGGGGAAGATTAGAACCAAAAGAGAGGGTTTTAATTCATGCGGGTGCGGGTGGTGTTGGT
CATGTAGCGATTCAATTAGCAAAATTGAAAGGTGCAATTGTTTCCACTACGGTTGGTTCGGAAGATAAGGCGAATTTTGT
AAAACAACTGGGTGCGGATCATGTGATTTTATATAAAAATACAGATTTTGCCCAAGCTGCTTTAGATTGGACGAACGGGG
AAGGTGTAGATTTAGCTTTTGATACTGTTGGCGGTGAAACTTTTCACAAAACCTTTCCCGCAGTGCGTATCTATGGCGAT
ATTGTGACGATTTTGGAACCAGATGCAAATACAGTTTGGAAAGTTGCCAGAAACCGCAATTTACGCATTGGCTTGGAATT
AATGCTGACACCGATGTTGTTAAATTTAGTGGAGGCGCAGCAACACCAGGCAGAAATTTTGACAGAATGTGCTGATTGGA
TTGATCAAGGTAAGTTAAAAATTCACGTTAGTCATAAGTTTCCTTTGCAAGATGCAGCTAAAGCTCATCAGTTACTTGAA
TCTGGCAGTATTGCGGGTAAAATTGTTCTGCTGATTAGCGATGAATGA

Upstream 100 bases:

>100_bases
CATAGCCCCAAAAGTTTGTTCTGTCTTGATTCTTAATTTTGAATTTTGAATTTTGAATTGGTATAAGTGTGCATCTAACT
TCAGATTGGAGGAAACAATT

Downstream 100 bases:

>100_bases
TAGAGAATCCTATTGCATACGTTGTTGACTTGCTGGCGGAAAGCTAAATTTTTCATAAGTTTGTGTGCGTTGTTAGTATT
ATTGCTCCCTTTGCCAGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKAVLMTAPGNPEVLQLQEVPNPGVPVGSTELLVRLVAAGINPIDTKLRKRGTFYPEQMPAILGCDGAGVVEAVGAGVQG
FRVGDAVYFCNGGLGGHQGNYAEYTIVDERFAAHKPASLTFAEAAAAPLVLITAWEALYERGRLEPKERVLIHAGAGGVG
HVAIQLAKLKGAIVSTTVGSEDKANFVKQLGADHVILYKNTDFAQAALDWTNGEGVDLAFDTVGGETFHKTFPAVRIYGD
IVTILEPDANTVWKVARNRNLRIGLELMLTPMLLNLVEAQQHQAEILTECADWIDQGKLKIHVSHKFPLQDAAKAHQLLE
SGSIAGKIVLLISDE

Sequences:

>Translated_335_residues
MKAVLMTAPGNPEVLQLQEVPNPGVPVGSTELLVRLVAAGINPIDTKLRKRGTFYPEQMPAILGCDGAGVVEAVGAGVQG
FRVGDAVYFCNGGLGGHQGNYAEYTIVDERFAAHKPASLTFAEAAAAPLVLITAWEALYERGRLEPKERVLIHAGAGGVG
HVAIQLAKLKGAIVSTTVGSEDKANFVKQLGADHVILYKNTDFAQAALDWTNGEGVDLAFDTVGGETFHKTFPAVRIYGD
IVTILEPDANTVWKVARNRNLRIGLELMLTPMLLNLVEAQQHQAEILTECADWIDQGKLKIHVSHKFPLQDAAKAHQLLE
SGSIAGKIVLLISDE
>Mature_335_residues
MKAVLMTAPGNPEVLQLQEVPNPGVPVGSTELLVRLVAAGINPIDTKLRKRGTFYPEQMPAILGCDGAGVVEAVGAGVQG
FRVGDAVYFCNGGLGGHQGNYAEYTIVDERFAAHKPASLTFAEAAAAPLVLITAWEALYERGRLEPKERVLIHAGAGGVG
HVAIQLAKLKGAIVSTTVGSEDKANFVKQLGADHVILYKNTDFAQAALDWTNGEGVDLAFDTVGGETFHKTFPAVRIYGD
IVTILEPDANTVWKVARNRNLRIGLELMLTPMLLNLVEAQQHQAEILTECADWIDQGKLKIHVSHKFPLQDAAKAHQLLE
SGSIAGKIVLLISDE

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=347, Percent_Identity=30.835734870317, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI22538444, Length=347, Percent_Identity=30.835734870317, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI194239674, Length=338, Percent_Identity=28.698224852071, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI13236495, Length=338, Percent_Identity=28.698224852071, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI47519420, Length=381, Percent_Identity=29.3963254593176, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI18379349, Length=349, Percent_Identity=27.2206303724928, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194239676, Length=335, Percent_Identity=28.6567164179104, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI24308257, Length=352, Percent_Identity=26.7045454545455, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI28557745, Length=231, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41872631, Length=147, Percent_Identity=35.3741496598639, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI67078404, Length=314, Percent_Identity=26.1146496815287, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI67078406, Length=305, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI90669511, Length=222, Percent_Identity=31.5315315315315, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226059159, Length=110, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226059133, Length=110, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226056130, Length=110, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=33.5365853658537, Blast_Score=147, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17507255, Length=202, Percent_Identity=34.1584158415842, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71987554, Length=210, Percent_Identity=34.7619047619048, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI212642053, Length=241, Percent_Identity=30.7053941908714, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=28.8235294117647, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324486, Length=223, Percent_Identity=28.6995515695067, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=218, Percent_Identity=30.2752293577982, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=223, Percent_Identity=29.1479820627803, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920632, Length=243, Percent_Identity=28.8065843621399, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330659, Length=243, Percent_Identity=28.8065843621399, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24581345, Length=231, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35884; Mature: 35884

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLMTAPGNPEVLQLQEVPNPGVPVGSTELLVRLVAAGINPIDTKLRKRGTFYPEQMP
CCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHCC
AILGCDGAGVVEAVGAGVQGFRVGDAVYFCNGGLGGHQGNYAEYTIVDERFAAHKPASLT
EEEECCCCCHHHHHCCCCCCEEECCEEEEECCCCCCCCCCCEEEEEEECHHHCCCCCCEE
FAEAAAAPLVLITAWEALYERGRLEPKERVLIHAGAGGVGHVAIQLAKLKGAIVSTTVGS
HHHHCCCCEEEEHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHEEEEHHCCEEEEEECCC
EDKANFVKQLGADHVILYKNTDFAQAALDWTNGEGVDLAFDTVGGETFHKTFPAVRIYGD
CHHHHHHHHCCCCEEEEEECCCHHHHEEECCCCCCCEEEEECCCCCHHHHHCCEEEEEEE
IVTILEPDANTVWKVARNRNLRIGLELMLTPMLLNLVEAQQHQAEILTECADWIDQGKLK
EEEEECCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
IHVSHKFPLQDAAKAHQLLESGSIAGKIVLLISDE
EEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MKAVLMTAPGNPEVLQLQEVPNPGVPVGSTELLVRLVAAGINPIDTKLRKRGTFYPEQMP
CCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHCC
AILGCDGAGVVEAVGAGVQGFRVGDAVYFCNGGLGGHQGNYAEYTIVDERFAAHKPASLT
EEEECCCCCHHHHHCCCCCCEEECCEEEEECCCCCCCCCCCEEEEEEECHHHCCCCCCEE
FAEAAAAPLVLITAWEALYERGRLEPKERVLIHAGAGGVGHVAIQLAKLKGAIVSTTVGS
HHHHCCCCEEEEHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHEEEEHHCCEEEEEECCC
EDKANFVKQLGADHVILYKNTDFAQAALDWTNGEGVDLAFDTVGGETFHKTFPAVRIYGD
CHHHHHHHHCCCCEEEEEECCCHHHHEEECCCCCCCEEEEECCCCCHHHHHCCEEEEEEE
IVTILEPDANTVWKVARNRNLRIGLELMLTPMLLNLVEAQQHQAEILTECADWIDQGKLK
EEEEECCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
IHVSHKFPLQDAAKAHQLLESGSIAGKIVLLISDE
EEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]