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The map label for this gene is hsdS [C]

Identifier: 17230179

GI number: 17230179

Start: 3277624

End: 3278907

Strand: Reverse

Name: hsdS [C]

Synonym: all2687

Alternate gene names: 17230179

Gene position: 3278907-3277624 (Counterclockwise)

Preceding gene: 17230180

Following gene: 17230178

Centisome position: 51.12

GC content: 36.21

Gene sequence:

>1284_bases
GTGGTTATGAAAACAAATTTTCCTGAAAGCTATCAAAAAACAGAGTTTGGAATCGTACCTAATGATTGGAAGATAAGAAA
GTTAGTAGAATGTTGTAATAAAATTACAGACGGAACTCACGATACACCAAAACCACTTGCTCAAGGAATACCATTTTTAA
CTGCTATTCATGTGAAAGAGGGTTTTATTGATTTCAATAATTGCTATTATTTGCCCCAAAGTATACATGAAAGTATTTAC
AAACGATGTAATCCAGAAAAGAATGATGTGCTTATGGTAAACATCGGTGCAGGAGTAGCTACAACTGCACTAATCGATGT
TGAATATGAATTTAGCCTTAAAAATGTTGCATTATTAAAACCTGATAAGAATAATTTAATCGGTTCTTATTTAAATTATT
GTCTTTCTCTTAATAAATTTAGAATTACCAATCAGCTTCTAAGTGGAGGAGCGCAACCGTTTCTGTCTCTAAAACAAATA
GGTGAAATTTCAATTCCTATCCCTCCAACAATAGAAGAACAAGAAGCGATCGCCCAATCCCTCAGTGATGTCGATGCCCT
GATTACAGAGTGCGATCGCATCATCGCCAAAAAGCACAACACCAAGCAAGGCACGATGCAGCAACTCCTCACGGGAGAGA
AACGCTTGCCGGGTTTTAGTGGCGAGTGGGAGGTGGAGGAATTTGAGCAAGTTCTAAAAGTGGTAGATGGAGATAGAGGA
GATAATTATCCAAGCAATGATGAGCTTTTTGACAATGGATATTGCTTGTTTTTAAGTGCCAAAAATGTCACAAAAGGAGG
GTTTAAGTTTTCGGATTGTACTTTTATAACAAAGGAAAAAGATAATTTATTAGGAAATGGAAAGCTATGTAAAAAAGATG
TGGTGTTAACAACTCGTGGGACTGTAGGTAATATTGCATTTTTTGATTATTCTGTCCCCTTTGAAAATATTCGGATAAAT
TCGGGAATGGTAATTTTAAGAAGTGAAGATAAGAATTTAGACAATAGTTATCTTTATAGTTTTTTGAAATCACATCTTTT
CCAAACTCAGATTGATAGGGCTGTATTTGGAAGCGCACAACCACAATTAACTGTAAAAGGGATTAGTAAATTTAAAATTC
CCGTCTCTTCTCTCCCTGAACAAAAAGCGATCGCCCAAATCCTCAGCGACATGGATACAGAAATCGCAGCCTTAGAACAA
AAGCGCGATAAATACAAAGCCATAAAACAGGGCATGATGCAAGAACTTCTCACCGGAAAAACGAGACTAATTTGCAGTTC
TTGA

Upstream 100 bases:

>100_bases
AATTGGCTGAACGGTATGATACACCTTTACCGGAGTTGACGAGTCGGGTGGATGAGTTGACGACTAAGGTTGAGGGGCAT
CTTCAGCAGATGGGGATTGT

Downstream 100 bases:

>100_bases
TCAACGTTAGAGTTTTCAACCGCCAATCTCTAGAATAGAAGCAAGAACAAAAGCTAAACCTTACTATGGAACACATTGCT
ACCAGCGAACTGCCTGAAAC

Product: type I restriction-modification enzyme S subunit

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MVMKTNFPESYQKTEFGIVPNDWKIRKLVECCNKITDGTHDTPKPLAQGIPFLTAIHVKEGFIDFNNCYYLPQSIHESIY
KRCNPEKNDVLMVNIGAGVATTALIDVEYEFSLKNVALLKPDKNNLIGSYLNYCLSLNKFRITNQLLSGGAQPFLSLKQI
GEISIPIPPTIEEQEAIAQSLSDVDALITECDRIIAKKHNTKQGTMQQLLTGEKRLPGFSGEWEVEEFEQVLKVVDGDRG
DNYPSNDELFDNGYCLFLSAKNVTKGGFKFSDCTFITKEKDNLLGNGKLCKKDVVLTTRGTVGNIAFFDYSVPFENIRIN
SGMVILRSEDKNLDNSYLYSFLKSHLFQTQIDRAVFGSAQPQLTVKGISKFKIPVSSLPEQKAIAQILSDMDTEIAALEQ
KRDKYKAIKQGMMQELLTGKTRLICSS

Sequences:

>Translated_427_residues
MVMKTNFPESYQKTEFGIVPNDWKIRKLVECCNKITDGTHDTPKPLAQGIPFLTAIHVKEGFIDFNNCYYLPQSIHESIY
KRCNPEKNDVLMVNIGAGVATTALIDVEYEFSLKNVALLKPDKNNLIGSYLNYCLSLNKFRITNQLLSGGAQPFLSLKQI
GEISIPIPPTIEEQEAIAQSLSDVDALITECDRIIAKKHNTKQGTMQQLLTGEKRLPGFSGEWEVEEFEQVLKVVDGDRG
DNYPSNDELFDNGYCLFLSAKNVTKGGFKFSDCTFITKEKDNLLGNGKLCKKDVVLTTRGTVGNIAFFDYSVPFENIRIN
SGMVILRSEDKNLDNSYLYSFLKSHLFQTQIDRAVFGSAQPQLTVKGISKFKIPVSSLPEQKAIAQILSDMDTEIAALEQ
KRDKYKAIKQGMMQELLTGKTRLICSS
>Mature_427_residues
MVMKTNFPESYQKTEFGIVPNDWKIRKLVECCNKITDGTHDTPKPLAQGIPFLTAIHVKEGFIDFNNCYYLPQSIHESIY
KRCNPEKNDVLMVNIGAGVATTALIDVEYEFSLKNVALLKPDKNNLIGSYLNYCLSLNKFRITNQLLSGGAQPFLSLKQI
GEISIPIPPTIEEQEAIAQSLSDVDALITECDRIIAKKHNTKQGTMQQLLTGEKRLPGFSGEWEVEEFEQVLKVVDGDRG
DNYPSNDELFDNGYCLFLSAKNVTKGGFKFSDCTFITKEKDNLLGNGKLCKKDVVLTTRGTVGNIAFFDYSVPFENIRIN
SGMVILRSEDKNLDNSYLYSFLKSHLFQTQIDRAVFGSAQPQLTVKGISKFKIPVSSLPEQKAIAQILSDMDTEIAALEQ
KRDKYKAIKQGMMQELLTGKTRLICSS

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 47896; Mature: 47896

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMKTNFPESYQKTEFGIVPNDWKIRKLVECCNKITDGTHDTPKPLAQGIPFLTAIHVKE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEHHH
GFIDFNNCYYLPQSIHESIYKRCNPEKNDVLMVNIGAGVATTALIDVEYEFSLKNVALLK
CEEECCCEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEEEEECCCEEEEEC
PDKNNLIGSYLNYCLSLNKFRITNQLLSGGAQPFLSLKQIGEISIPIPPTIEEQEAIAQS
CCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCCCEECCCCCCCCHHHHHHHH
LSDVDALITECDRIIAKKHNTKQGTMQQLLTGEKRLPGFSGEWEVEEFEQVLKVVDGDRG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHCCCCC
DNYPSNDELFDNGYCLFLSAKNVTKGGFKFSDCTFITKEKDNLLGNGKLCKKDVVLTTRG
CCCCCCCCEECCCEEEEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCEEEEECC
TVGNIAFFDYSVPFENIRINSGMVILRSEDKNLDNSYLYSFLKSHLFQTQIDRAVFGSAQ
CCCCEEEEEECCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PQLTVKGISKFKIPVSSLPEQKAIAQILSDMDTEIAALEQKRDKYKAIKQGMMQELLTGK
CCEEEECCCEEECCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TRLICSS
CEEEECC
>Mature Secondary Structure
MVMKTNFPESYQKTEFGIVPNDWKIRKLVECCNKITDGTHDTPKPLAQGIPFLTAIHVKE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEHHH
GFIDFNNCYYLPQSIHESIYKRCNPEKNDVLMVNIGAGVATTALIDVEYEFSLKNVALLK
CEEECCCEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEEEEECCCEEEEEC
PDKNNLIGSYLNYCLSLNKFRITNQLLSGGAQPFLSLKQIGEISIPIPPTIEEQEAIAQS
CCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCCCEECCCCCCCCHHHHHHHH
LSDVDALITECDRIIAKKHNTKQGTMQQLLTGEKRLPGFSGEWEVEEFEQVLKVVDGDRG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHCCCCC
DNYPSNDELFDNGYCLFLSAKNVTKGGFKFSDCTFITKEKDNLLGNGKLCKKDVVLTTRG
CCCCCCCCEECCCEEEEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCEEEEECC
TVGNIAFFDYSVPFENIRINSGMVILRSEDKNLDNSYLYSFLKSHLFQTQIDRAVFGSAQ
CCCCEEEEEECCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PQLTVKGISKFKIPVSSLPEQKAIAQILSDMDTEIAALEQKRDKYKAIKQGMMQELLTGK
CCEEEECCCEEECCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TRLICSS
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]