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The map label for this gene is eryA [H]

Identifier: 17230127

GI number: 17230127

Start: 3148687

End: 3153384

Strand: Reverse

Name: eryA [H]

Synonym: all2635

Alternate gene names: 17230127

Gene position: 3153384-3148687 (Counterclockwise)

Preceding gene: 17230128

Following gene: 17230125

Centisome position: 49.17

GC content: 42.27

Gene sequence:

>4698_bases
ATGTCTTATTCCATTGATGATATTAAAAATCACCCTGCATCTGAGCGTATTTTGGCTGCGCTTAAGGAGGCTCGGACTAA
GTTAGAAGCGGTGGAATTAGAAAGGTCTGAGGAAGTTGCTATTGTTGGGATGGCGGGGCGGTTTCCGGGGGCTAAAAATG
TTGATGAGTTTTGGGATAATCTGAAAAATGGTATTAACTCGATTAAGTTTTTAAGTAATGAAGATTTATTAGCAAATGGG
GTAAAGGCGGAGGATTTAGAAAAACAAAATTATGTCCGGGCTTATGCTAGTTTGGCGGGAATTGATGAGTTTGATGCCGG
TTTTTTTGGTTATTCTCCTAGAGAAGCGGAAATTCTCGATCCTCAGCATCGGTTGTTTTTAGAATGTGCTTGGGAAGCTT
TAGAAAATGCTGGCTATGATTCAGAGCAGTATTCGGGTAATATTGCTGTGTATGGTGGGGCTGCACTGAATAGTTATTTG
GTGAATTTAGCGAGTAATTCTAATTATCGAGAAAATAGCGATCGCACTCAAGTCGTGATCAGCAATGTTATGGGTTTAAT
GCCTACTCGTGTCTCCTATAAATTGAATTTGACAGGTGCGAGTTGTGGTATTCAAACTGGTTGTTCTACTTCTTTGGTCA
GTGTACATATTGCTTGTCAAAGTTTATTAAATAAAGAATGCGATATAGCACTTGCTGGTGGTGTGTCTATCGGTATAGGG
GAAAAAGCAGGTTATCTTTATCAAGAAGATGGTGTACTTTCTCCAGATGGTTATTGTCGGGCTTTTGATGTTAACGCGAA
AGGCACAGTATTCGGTAATGGTGTGGGAATTGTTGTCTTGAAAAGACTGCGGGATGCTATTCAAGACGGCGACCATATTT
ATGCAATTATCAAAGCAACAGCAATAAATAATGACGGTTCGCAAAAAGTAGGTTTAACTGCACCCAGTGTTACCGGACAA
GCAAAAGCTATCACTACTGCGTTAACAAAAGCTAAGATAAATCCAGAGACAATTCAATATATTGAAACTCACGGAACAGG
AACAGCTTTAGGTGATCCTATTGAAATTGCAGCTTTAACTAAAGCATTTTCACCACATACTCATCAAAAACAATTCTGTG
CTGTTGGTTCAGTTAAAACTAATATTGGTCATTTAGATGCGGCTGCGGGTATCAGTGGTTTAATTAAAACTGCTTTGGCT
CTCAAACACAAACAAATTCCTCCAAGTTTAAATTTTACGGCGGCGAATCCGCAAATTGATTTTGCTAATAGTCCATTTTT
TGTTAATACTCAGTTGACACCTTGGATAAATCATCAACACCCAAGAAGGGCTGGAGTTAGTTCCTTTGGGATGGGTGGAA
CTAATGCTCATGCAATTTTAGAAGAAGCACCAACACAATTCAAAATTCAAAATTCAAAATTCAAAATTAATTATCATCTA
TTATGTTTATCAGCTAAAAGTGAGAAAGCACTTGAGCAAGCAACAATCAACCTTGCTACACATTTACAAAAGCATCCAGA
ATTAAACCTTGCAGATGTAGCTTACACTCTCCAAATTGGTAGACGAGCATTTAACCATCGTCGTTGCTTAGTTTGTCAAA
CCCCTGCCCAAGCAATTGAAATCCTCACAGGAGTTGATGCTTCCCAACTGTTGAGTTATTCCCCAGAAAACACCGAACCC
AGCATAGTTTTTATGTTCCCTGGACAGGGTAGCCAATACCTCAACATGGGACAAGAACTCTACAACACCGAACCAGTTTT
CCGCAAAGAAATTGACCATTGCAGCGAATTATTACAACCACATCTAGGCTGTGATTTACCTTCCATCCTATTTAAACAGG
ACAACGAAAATTCACCCAGTCCCCAATCCCCAGTCCCCAATCTCAATTACGAATTACGAATTACGAATTACGAATTACTA
ACCCAAACCACCTACGCCCAACCTGCTCTATTCGCCGTAGAGTACGCCCTAGCGAAACTCTGGTTATCCTATGGTATTCA
GCCACAGGCTATGATTGGTCACAGCATTGGGGAATATGTGGCTGCAACTTTGGCGGGTGTTTTCACCTTAGCTGATGCTT
TGGCAATAGTGGCACAGCGCGGAAAATTGATGCAACAATGTCCATCGGGAGTCATGCTTTCGGTTTCCCTTGCGCCTGAG
AAATTGCAACCGTTTTTGACTGATGATTTAGTCATCGCTGTCCATAACGCACCTGAGTTATGCGTCGTATCGGGAACAGA
AGCCGCAATTACTCTACTAGAAAAACTGCTCACACATCAAAATATTACTCATCGACGTTTACATACTTCCCATGCTTTCC
ATTCACCCTTGATGGAAACTGCTGTTACTCCCTTAACGCAAATATTACAAAATATCTCCCTCCATCCGCCACAAATTCCC
TTCATTTCCAACGTTACGGGAACTTGGATAACTCCAGAACAAGCCACAAACCCTAATTACTGGGCTACCCATTTACGTCA
ACCAGTGTTATTTGCTGAAGGAATTACCGAACTCCAACAAACACCCAATCAGATTTTTGTAGAGGTTGGTTTTGGTCAAA
CTTTAAGTACCTTCGTCAGACAGTTTCCCGATGCACCCCCCACCTTATCATCTGGACGACATCCCCAAGACACCCAATCT
GATGTAGCTTTGATTTGCAAAACCTTGGGACAACTTTGGCTCAGGGGTGTGACTATCAACTGGTCAGAACTTTATACCCA
ACAGCAACGCCGAAGATTACCCCTCCCAACTTACCCCTTTGAACGTCAACGCTATTGGGTAGAAAGGGATACATTACCAG
AAACTACTTCTAATACCTCTAAAACGCTCCAGAAGCAGGAACAAATCTCAAATTGGTTTTATTTGCCCTCTTGGAGACAA
AAACCCCTGTTGCGTTCTGCTGCACCGTTAAATAAACAGCGATATTTAGTATTTTGTCATGCTGGGAATGCTGGGGAAAG
ATTAGTACAACATCTTCAGGAAACGGGACAGGAAGTAGTAACTGTCAAACCGGGAGAGGGATTTACTCAAGAAGGTGATA
ATTATGCGATCGCACCTCATAACCCTGAAGACTACAAAACACTGTGGTTACAATTACAAACAGATGATAAGTTACCTGAT
GTAATTATACATTCCTGGACTCTCCAAGAGCGCACAAATTTTCAACAACAGCAAAATCTGGGTTTTTACAGTTTACTTTG
GCTCACTCAGGCTTTATCTTCCTCATCCCTGTCAATTTATGTACTGACTCAGCAAGTACAGAATGTTCTGGGAAATGAAA
ATCTTAACCCTGATGATGCTACGATTCTGGGTTTAGTGAAGGTAATTCCCCAAGAATACCCGAATTTGACTTGTCAACAT
ATTGATGTGTCCATTTCTGACATTAACTTCCAGCAATTAGTTAGGGAAATCAACATCCCACCCGTCCTATCGGACACCCT
CCCCTTGGAAAAGGGAGGGTTAAGAATGAGTGTTGCTTATCGGGGGAAAACTCGCTGGATACAAGAATTTCAACCAATTT
CTCTCCCCGAACCCACCCAATTACCCCTAATTACAGGGGGTGTATATGTGATTGCTGGGGATTTAGTGGAAGGTTTAGGG
TTAATTTATGCCAAGTTCCTCGCAGCAACAGTCAATGCTAAATTAGTGTTTCTGGGACGCTCAGATTTACCACAACCAAA
AGAATGGGATAATTGGCTGGCTACCCACGGTCGTCAAGACGCTGTGAGTCATTGTATTCAACAACTGCAAGGTTTACAGG
CTCAAGGGTGTGAATTTTTATTTACCACTGTTGACTTAGCAGAGATTAGCCAAGTTGAGGATGCGATCGCTCAAGCCCTC
ACGCGATTTGGTAAAATCAACGGTGTGATTCATGCTGGCGTAATGGGCGATCGCGCTAGTTGTCTAATTCGCAATCTCAC
CATCCCAGAGTGTGAAAAACAATTCCACACCAAAATTCACGGTTTGCTGGCGTTAGAAACAGCACTCAAAAATCAACCCC
TAGACTTCTTCCTCTTGCAATCATCCCTCTCGGCTGTCGTTGGTGGTATAGGCTTTGCGGCGTATGCGGGGGCGAACTGC
TTTATGGATGCGATCGCTCATCAACGCACTCAAAACAGTAACACACATTGGATTAGTATCAACTGGGATGCCGTCAGTTT
AGCAGAAATCACCACTTCCACAGGTGCAACTCTCATAGATTTAGCCATGACTTCCCAGGAAGTTTGGCAAGTCACAGAAC
GTATTCTGGCGCAACCCATAGCAGCACAAATCACCGTTTCCCCCGTAGACTTAGCATCTCGCCAACAATCCCAGCCACTA
GAACAATCTACAACTAATCACGCCCGCCCCCAAATTACCGCTACCTACCTTCCCCCCAGCAATGAAATTGAAGCCAGAGT
CACCCAAGTAATGGAGAGTTTATTGGGAATCGCTCCTATTGGGGTTAATGATAACTTCTTTGAGTTAGGAGGACATTCCC
TGTTAGCAATTCAAGCAGTTTCACAGCTACGGGAAGAATTTCAAGTAGAATTACCCATGCGACAATTTTTATTTGAGTCA
CCCACAATTGGGGGGATAGCCAAAATTATCATTGAAAATCAATCGCCTATTACTGATGATACAGAAGCCTTAGCAGCACT
AATAGATCAAGTTGAACAAATGACACCCATCCAAGTACAACAATTGCTAGCAGAATAG

Upstream 100 bases:

>100_bases
GAGAATTTGGAGAAATGTGTCACGCAGAGACGCAGAAGCGCAGAGTGAGATTTATAAGTTTTCTTAGTTCCATATTAGAG
ATTTTAAGAGTAGAAAAATT

Downstream 100 bases:

>100_bases
TAAGGATTCAGGTCTAATACCACTAACTATGTTTTCCCTAAGCTTCGTATAATTCTGCCCTCTTTTAGAGAGTTTGAAAA
ATTAGAAATTGTAACCAACA

Product: polyketide synthase type I

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase I; DEBS 1; ORF 1 [H]

Number of amino acids: Translated: 1565; Mature: 1564

Protein sequence:

>1565_residues
MSYSIDDIKNHPASERILAALKEARTKLEAVELERSEEVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANG
VKAEDLEKQNYVRAYASLAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALNSYL
VNLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSVHIACQSLLNKECDIALAGGVSIGIG
EKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGVGIVVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQ
AKAITTALTKAKINPETIQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLIKTALA
LKHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTNAHAILEEAPTQFKIQNSKFKINYHL
LCLSAKSEKALEQATINLATHLQKHPELNLADVAYTLQIGRRAFNHRRCLVCQTPAQAIEILTGVDASQLLSYSPENTEP
SIVFMFPGQGSQYLNMGQELYNTEPVFRKEIDHCSELLQPHLGCDLPSILFKQDNENSPSPQSPVPNLNYELRITNYELL
TQTTYAQPALFAVEYALAKLWLSYGIQPQAMIGHSIGEYVAATLAGVFTLADALAIVAQRGKLMQQCPSGVMLSVSLAPE
KLQPFLTDDLVIAVHNAPELCVVSGTEAAITLLEKLLTHQNITHRRLHTSHAFHSPLMETAVTPLTQILQNISLHPPQIP
FISNVTGTWITPEQATNPNYWATHLRQPVLFAEGITELQQTPNQIFVEVGFGQTLSTFVRQFPDAPPTLSSGRHPQDTQS
DVALICKTLGQLWLRGVTINWSELYTQQQRRRLPLPTYPFERQRYWVERDTLPETTSNTSKTLQKQEQISNWFYLPSWRQ
KPLLRSAAPLNKQRYLVFCHAGNAGERLVQHLQETGQEVVTVKPGEGFTQEGDNYAIAPHNPEDYKTLWLQLQTDDKLPD
VIIHSWTLQERTNFQQQQNLGFYSLLWLTQALSSSSLSIYVLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQH
IDVSISDINFQQLVREINIPPVLSDTLPLEKGGLRMSVAYRGKTRWIQEFQPISLPEPTQLPLITGGVYVIAGDLVEGLG
LIYAKFLAATVNAKLVFLGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFLFTTVDLAEISQVEDAIAQAL
TRFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIHGLLALETALKNQPLDFFLLQSSLSAVVGGIGFAAYAGANC
FMDAIAHQRTQNSNTHWISINWDAVSLAEITTSTGATLIDLAMTSQEVWQVTERILAQPIAAQITVSPVDLASRQQSQPL
EQSTTNHARPQITATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGGHSLLAIQAVSQLREEFQVELPMRQFLFES
PTIGGIAKIIIENQSPITDDTEALAALIDQVEQMTPIQVQQLLAE

Sequences:

>Translated_1565_residues
MSYSIDDIKNHPASERILAALKEARTKLEAVELERSEEVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANG
VKAEDLEKQNYVRAYASLAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALNSYL
VNLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSVHIACQSLLNKECDIALAGGVSIGIG
EKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGVGIVVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQ
AKAITTALTKAKINPETIQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLIKTALA
LKHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTNAHAILEEAPTQFKIQNSKFKINYHL
LCLSAKSEKALEQATINLATHLQKHPELNLADVAYTLQIGRRAFNHRRCLVCQTPAQAIEILTGVDASQLLSYSPENTEP
SIVFMFPGQGSQYLNMGQELYNTEPVFRKEIDHCSELLQPHLGCDLPSILFKQDNENSPSPQSPVPNLNYELRITNYELL
TQTTYAQPALFAVEYALAKLWLSYGIQPQAMIGHSIGEYVAATLAGVFTLADALAIVAQRGKLMQQCPSGVMLSVSLAPE
KLQPFLTDDLVIAVHNAPELCVVSGTEAAITLLEKLLTHQNITHRRLHTSHAFHSPLMETAVTPLTQILQNISLHPPQIP
FISNVTGTWITPEQATNPNYWATHLRQPVLFAEGITELQQTPNQIFVEVGFGQTLSTFVRQFPDAPPTLSSGRHPQDTQS
DVALICKTLGQLWLRGVTINWSELYTQQQRRRLPLPTYPFERQRYWVERDTLPETTSNTSKTLQKQEQISNWFYLPSWRQ
KPLLRSAAPLNKQRYLVFCHAGNAGERLVQHLQETGQEVVTVKPGEGFTQEGDNYAIAPHNPEDYKTLWLQLQTDDKLPD
VIIHSWTLQERTNFQQQQNLGFYSLLWLTQALSSSSLSIYVLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQH
IDVSISDINFQQLVREINIPPVLSDTLPLEKGGLRMSVAYRGKTRWIQEFQPISLPEPTQLPLITGGVYVIAGDLVEGLG
LIYAKFLAATVNAKLVFLGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFLFTTVDLAEISQVEDAIAQAL
TRFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIHGLLALETALKNQPLDFFLLQSSLSAVVGGIGFAAYAGANC
FMDAIAHQRTQNSNTHWISINWDAVSLAEITTSTGATLIDLAMTSQEVWQVTERILAQPIAAQITVSPVDLASRQQSQPL
EQSTTNHARPQITATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGGHSLLAIQAVSQLREEFQVELPMRQFLFES
PTIGGIAKIIIENQSPITDDTEALAALIDQVEQMTPIQVQQLLAE
>Mature_1564_residues
SYSIDDIKNHPASERILAALKEARTKLEAVELERSEEVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSNEDLLANGV
KAEDLEKQNYVRAYASLAGIDEFDAGFFGYSPREAEILDPQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALNSYLV
NLASNSNYRENSDRTQVVISNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSVHIACQSLLNKECDIALAGGVSIGIGE
KAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGVGIVVLKRLRDAIQDGDHIYAIIKATAINNDGSQKVGLTAPSVTGQA
KAITTALTKAKINPETIQYIETHGTGTALGDPIEIAALTKAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLIKTALAL
KHKQIPPSLNFTAANPQIDFANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTNAHAILEEAPTQFKIQNSKFKINYHLL
CLSAKSEKALEQATINLATHLQKHPELNLADVAYTLQIGRRAFNHRRCLVCQTPAQAIEILTGVDASQLLSYSPENTEPS
IVFMFPGQGSQYLNMGQELYNTEPVFRKEIDHCSELLQPHLGCDLPSILFKQDNENSPSPQSPVPNLNYELRITNYELLT
QTTYAQPALFAVEYALAKLWLSYGIQPQAMIGHSIGEYVAATLAGVFTLADALAIVAQRGKLMQQCPSGVMLSVSLAPEK
LQPFLTDDLVIAVHNAPELCVVSGTEAAITLLEKLLTHQNITHRRLHTSHAFHSPLMETAVTPLTQILQNISLHPPQIPF
ISNVTGTWITPEQATNPNYWATHLRQPVLFAEGITELQQTPNQIFVEVGFGQTLSTFVRQFPDAPPTLSSGRHPQDTQSD
VALICKTLGQLWLRGVTINWSELYTQQQRRRLPLPTYPFERQRYWVERDTLPETTSNTSKTLQKQEQISNWFYLPSWRQK
PLLRSAAPLNKQRYLVFCHAGNAGERLVQHLQETGQEVVTVKPGEGFTQEGDNYAIAPHNPEDYKTLWLQLQTDDKLPDV
IIHSWTLQERTNFQQQQNLGFYSLLWLTQALSSSSLSIYVLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQHI
DVSISDINFQQLVREINIPPVLSDTLPLEKGGLRMSVAYRGKTRWIQEFQPISLPEPTQLPLITGGVYVIAGDLVEGLGL
IYAKFLAATVNAKLVFLGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFLFTTVDLAEISQVEDAIAQALT
RFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIHGLLALETALKNQPLDFFLLQSSLSAVVGGIGFAAYAGANCF
MDAIAHQRTQNSNTHWISINWDAVSLAEITTSTGATLIDLAMTSQEVWQVTERILAQPIAAQITVSPVDLASRQQSQPLE
QSTTNHARPQITATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGGHSLLAIQAVSQLREEFQVELPMRQFLFESP
TIGGIAKIIIENQSPITDDTEALAALIDQVEQMTPIQVQQLLAE

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Specific For Elongation From C-10 To Unsaturated C-16 And C-18 Fatty Acids. [C]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=892, Percent_Identity=26.0089686098655, Blast_Score=284, Evalue=5e-76,
Organism=Homo sapiens, GI8923559, Length=274, Percent_Identity=30.6569343065693, Blast_Score=111, Evalue=6e-24,
Organism=Homo sapiens, GI51243059, Length=268, Percent_Identity=31.3432835820896, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=35.8108108108108, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI1788663, Length=279, Percent_Identity=28.673835125448, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1787334, Length=313, Percent_Identity=26.8370607028754, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1787337, Length=296, Percent_Identity=26.3513513513513, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=955, Percent_Identity=28.7958115183246, Blast_Score=346, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI212642053, Length=931, Percent_Identity=25.9935553168636, Blast_Score=264, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71984332, Length=335, Percent_Identity=26.5671641791045, Blast_Score=97, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71983541, Length=276, Percent_Identity=28.9855072463768, Blast_Score=92, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71983535, Length=261, Percent_Identity=29.5019157088123, Blast_Score=87, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=461, Percent_Identity=25.5965292841649, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330659, Length=862, Percent_Identity=27.1461716937355, Blast_Score=276, Evalue=9e-74,
Organism=Drosophila melanogaster, GI19920632, Length=862, Percent_Identity=27.1461716937355, Blast_Score=276, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24581345, Length=839, Percent_Identity=27.1752085816448, Blast_Score=260, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24644341, Length=274, Percent_Identity=29.5620437956204, Blast_Score=94, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24665753, Length=336, Percent_Identity=27.9761904761905, Blast_Score=78, Evalue=4e-14,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 172319; Mature: 172187

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSIDDIKNHPASERILAALKEARTKLEAVELERSEEVAIVGMAGRFPGAKNVDEFWDN
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHH
LKNGINSIKFLSNEDLLANGVKAEDLEKQNYVRAYASLAGIDEFDAGFFGYSPREAEILD
HHHHHHHEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALNSYLVNLASNSNYRENSDRTQVVI
HHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHH
SNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSVHIACQSLLNKECDIALAGGVSIGIG
HHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEEECC
EKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGVGIVVLKRLRDAIQDGDHIYAIIKAT
CCCCCEECCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEE
AINNDGSQKVGLTAPSVTGQAKAITTALTKAKINPETIQYIETHGTGTALGDPIEIAALT
EECCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCHHHHHHH
KAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLIKTALALKHKQIPPSLNFTAANPQID
HHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEE
FANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTNAHAILEEAPTQFKIQNSKFKINYHL
ECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCEEEEEEEE
LCLSAKSEKALEQATINLATHLQKHPELNLADVAYTLQIGRRAFNHRRCLVCQTPAQAIE
EEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
ILTGVDASQLLSYSPENTEPSIVFMFPGQGSQYLNMGQELYNTEPVFRKEIDHCSELLQP
HHHCCCHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
HLGCDLPSILFKQDNENSPSPQSPVPNLNYELRITNYELLTQTTYAQPALFAVEYALAKL
HCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECEEEEEECCCCCHHHHHHHHHHHHH
WLSYGIQPQAMIGHSIGEYVAATLAGVFTLADALAIVAQRGKLMQQCPSGVMLSVSLAPE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHH
KLQPFLTDDLVIAVHNAPELCVVSGTEAAITLLEKLLTHQNITHRRLHTSHAFHSPLMET
HHCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVTPLTQILQNISLHPPQIPFISNVTGTWITPEQATNPNYWATHLRQPVLFAEGITELQQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHC
TPNQIFVEVGFGQTLSTFVRQFPDAPPTLSSGRHPQDTQSDVALICKTLGQLWLRGVTIN
CCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEC
WSELYTQQQRRRLPLPTYPFERQRYWVERDTLPETTSNTSKTLQKQEQISNWFYLPSWRQ
HHHHHHHHHHCCCCCCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHCEEECCCCCC
KPLLRSAAPLNKQRYLVFCHAGNAGERLVQHLQETGQEVVTVKPGEGFTQEGDNYAIAPH
CCHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCC
NPEDYKTLWLQLQTDDKLPDVIIHSWTLQERTNFQQQQNLGFYSLLWLTQALSSSSLSIY
CCCCCEEEEEEEECCCCCCCCEEEEEECHHHHCHHHHHCCCHHHHHHHHHHHCCCCCEEE
VLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQHIDVSISDINFQQLVREINIP
EEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHCCCC
PVLSDTLPLEKGGLRMSVAYRGKTRWIQEFQPISLPEPTQLPLITGGVYVIAGDLVEGLG
CCCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCEEECCEEEEEHHHHHHHH
LIYAKFLAATVNAKLVFLGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFL
HHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEE
FTTVDLAEISQVEDAIAQALTRFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIH
EEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHEECCCCCHHHHHHHHHHH
GLLALETALKNQPLDFFLLQSSLSAVVGGIGFAAYAGANCFMDAIAHQRTQNSNTHWISI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEE
NWDAVSLAEITTSTGATLIDLAMTSQEVWQVTERILAQPIAAQITVSPVDLASRQQSQPL
ECCEEEEEHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHEEEECCHHHHHHHHCCCH
EQSTTNHARPQITATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGGHSLLAIQAV
HHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHH
SQLREEFQVELPMRQFLFESPTIGGIAKIIIENQSPITDDTEALAALIDQVEQMTPIQVQ
HHHHHHHEECCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHH
QLLAE
HHHCC
>Mature Secondary Structure 
SYSIDDIKNHPASERILAALKEARTKLEAVELERSEEVAIVGMAGRFPGAKNVDEFWDN
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHH
LKNGINSIKFLSNEDLLANGVKAEDLEKQNYVRAYASLAGIDEFDAGFFGYSPREAEILD
HHHHHHHEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PQHRLFLECAWEALENAGYDSEQYSGNIAVYGGAALNSYLVNLASNSNYRENSDRTQVVI
HHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHH
SNVMGLMPTRVSYKLNLTGASCGIQTGCSTSLVSVHIACQSLLNKECDIALAGGVSIGIG
HHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEEECC
EKAGYLYQEDGVLSPDGYCRAFDVNAKGTVFGNGVGIVVLKRLRDAIQDGDHIYAIIKAT
CCCCCEECCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEE
AINNDGSQKVGLTAPSVTGQAKAITTALTKAKINPETIQYIETHGTGTALGDPIEIAALT
EECCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCHHHHHHH
KAFSPHTHQKQFCAVGSVKTNIGHLDAAAGISGLIKTALALKHKQIPPSLNFTAANPQID
HHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEE
FANSPFFVNTQLTPWINHQHPRRAGVSSFGMGGTNAHAILEEAPTQFKIQNSKFKINYHL
ECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCEEEEEEEE
LCLSAKSEKALEQATINLATHLQKHPELNLADVAYTLQIGRRAFNHRRCLVCQTPAQAIE
EEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
ILTGVDASQLLSYSPENTEPSIVFMFPGQGSQYLNMGQELYNTEPVFRKEIDHCSELLQP
HHHCCCHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
HLGCDLPSILFKQDNENSPSPQSPVPNLNYELRITNYELLTQTTYAQPALFAVEYALAKL
HCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECEEEEEECCCCCHHHHHHHHHHHHH
WLSYGIQPQAMIGHSIGEYVAATLAGVFTLADALAIVAQRGKLMQQCPSGVMLSVSLAPE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHH
KLQPFLTDDLVIAVHNAPELCVVSGTEAAITLLEKLLTHQNITHRRLHTSHAFHSPLMET
HHCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVTPLTQILQNISLHPPQIPFISNVTGTWITPEQATNPNYWATHLRQPVLFAEGITELQQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHC
TPNQIFVEVGFGQTLSTFVRQFPDAPPTLSSGRHPQDTQSDVALICKTLGQLWLRGVTIN
CCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEC
WSELYTQQQRRRLPLPTYPFERQRYWVERDTLPETTSNTSKTLQKQEQISNWFYLPSWRQ
HHHHHHHHHHCCCCCCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHCEEECCCCCC
KPLLRSAAPLNKQRYLVFCHAGNAGERLVQHLQETGQEVVTVKPGEGFTQEGDNYAIAPH
CCHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCC
NPEDYKTLWLQLQTDDKLPDVIIHSWTLQERTNFQQQQNLGFYSLLWLTQALSSSSLSIY
CCCCCEEEEEEEECCCCCCCCEEEEEECHHHHCHHHHHCCCHHHHHHHHHHHCCCCCEEE
VLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQHIDVSISDINFQQLVREINIP
EEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHCCCC
PVLSDTLPLEKGGLRMSVAYRGKTRWIQEFQPISLPEPTQLPLITGGVYVIAGDLVEGLG
CCCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCEEECCEEEEEHHHHHHHH
LIYAKFLAATVNAKLVFLGRSDLPQPKEWDNWLATHGRQDAVSHCIQQLQGLQAQGCEFL
HHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEE
FTTVDLAEISQVEDAIAQALTRFGKINGVIHAGVMGDRASCLIRNLTIPECEKQFHTKIH
EEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHEECCCCCHHHHHHHHHHH
GLLALETALKNQPLDFFLLQSSLSAVVGGIGFAAYAGANCFMDAIAHQRTQNSNTHWISI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEE
NWDAVSLAEITTSTGATLIDLAMTSQEVWQVTERILAQPIAAQITVSPVDLASRQQSQPL
ECCEEEEEHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHEEEECCHHHHHHHHCCCH
EQSTTNHARPQITATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGGHSLLAIQAV
HHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHH
SQLREEFQVELPMRQFLFESPTIGGIAKIIIENQSPITDDTEALAALIDQVEQMTPIQVQ
HHHHHHHEECCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHH
QLLAE
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 8386127 [H]