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The map label for this gene is yfhA [H]

Identifier: 17230077

GI number: 17230077

Start: 3090264

End: 3091304

Strand: Reverse

Name: yfhA [H]

Synonym: all2585

Alternate gene names: 17230077

Gene position: 3091304-3090264 (Counterclockwise)

Preceding gene: 17230078

Following gene: 17230076

Centisome position: 48.2

GC content: 46.88

Gene sequence:

>1041_bases
ATGAAGGTTGATTGGCTCGTCATCCGTTCCGAAACCATGTCTTTGCGGATTGACCGACGTGTACCACCAATATTGCTATG
TTTGGTAGTGGCTATTGTGGTAGCGATGGTAATGAACTTAGGGCGGGGTGAATATCCCATTGCGCCCTTAGATATCATCA
AAACAGTATTAGGTATAGATACAGGCAACCCAGATCATGCTTTTGTGATTTACAACCTGCGTCTACCCCGTACCCTTGTC
GCTTGCATGGTAGGAGTGGCACTAGCCGTTGCCGGGACTATCTTTCAAGGCATCACACGCAACCCACTAGCTGATCCCGG
TATTATTGGCATTAATGCCGGGGCAAGTCTAGCAGCAGTTACAGTAATTGTCCTATTTCCCTCAGCGCCCATTTACACTT
TGCCTTTATCAGCCTTTGCAGGTGCTTTATTAATGGCTGGTTTAATTTACTCCTTAGCTTGGAACAATGGTAGTTCCCCC
GTTTTGTTTATTTTAATGGGTGTGGGATTATCTGCGATCGCAGGTGCTTTCACCAGCTTGATGATTACCTTTGGCGATAT
CTATAGCGTCAGTGACGCTTTGGTATGGTTAGCGGGTAGTGTCTACGGACGCACCTGGGAACAAGTCTTTTCCTTCTTAC
CTTGGTTAATCGTTTTTGTCCCGATGGCGTTGACATTAGCCAGACATTTGAACACCTTAAATTTGGGAGATGATGTTGCC
AAAGGTTTAGGTACTCGTGTGGAATGGCAGCGTGGTTTGCTAGTGCTAGTAGGTGTAGCATTGGCAGGTGCAGGAGTCGC
CACAGCCGGAATGATTGGTTTTGTAGGATTAATAGCACCCCATTTAGGCAGACAGTTAGTAGGTACAAATCATCAAGGCT
TGCTCCCTACCTCTGCGTTGTTGGGAGGGATGCTTGTTGTTGTGGCAGACTTCTTGGGACGAACCCTCTTTGCACCTATC
GAAATTCCTTGTGGCGTAGTGACAGCTGCCGTCGGTGCGCCTTATTTCCTCTATTTGTTAATTCGTAATCGCAAGAAGTA
G

Upstream 100 bases:

>100_bases
CCCGTGTATTACTCAAACCCCAGGAATTACCTGTGGGAGTAATGACAGCATTGGTTGGCGCACCCTTTTTTGTTTACTTG
GCTAAATCAAAGGTGAAGAA

Downstream 100 bases:

>100_bases
GGATGGGTTCTGTGAGATATTCACACAGAAAACACATATGTCGGTTAAACCCGCCCGTTTAACACTCAACAGTCAACACT
CAACAGTCAACACTCAAAAA

Product: iron(III) dicitrate transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKVDWLVIRSETMSLRIDRRVPPILLCLVVAIVVAMVMNLGRGEYPIAPLDIIKTVLGIDTGNPDHAFVIYNLRLPRTLV
ACMVGVALAVAGTIFQGITRNPLADPGIIGINAGASLAAVTVIVLFPSAPIYTLPLSAFAGALLMAGLIYSLAWNNGSSP
VLFILMGVGLSAIAGAFTSLMITFGDIYSVSDALVWLAGSVYGRTWEQVFSFLPWLIVFVPMALTLARHLNTLNLGDDVA
KGLGTRVEWQRGLLVLVGVALAGAGVATAGMIGFVGLIAPHLGRQLVGTNHQGLLPTSALLGGMLVVVADFLGRTLFAPI
EIPCGVVTAAVGAPYFLYLLIRNRKK

Sequences:

>Translated_346_residues
MKVDWLVIRSETMSLRIDRRVPPILLCLVVAIVVAMVMNLGRGEYPIAPLDIIKTVLGIDTGNPDHAFVIYNLRLPRTLV
ACMVGVALAVAGTIFQGITRNPLADPGIIGINAGASLAAVTVIVLFPSAPIYTLPLSAFAGALLMAGLIYSLAWNNGSSP
VLFILMGVGLSAIAGAFTSLMITFGDIYSVSDALVWLAGSVYGRTWEQVFSFLPWLIVFVPMALTLARHLNTLNLGDDVA
KGLGTRVEWQRGLLVLVGVALAGAGVATAGMIGFVGLIAPHLGRQLVGTNHQGLLPTSALLGGMLVVVADFLGRTLFAPI
EIPCGVVTAAVGAPYFLYLLIRNRKK
>Mature_346_residues
MKVDWLVIRSETMSLRIDRRVPPILLCLVVAIVVAMVMNLGRGEYPIAPLDIIKTVLGIDTGNPDHAFVIYNLRLPRTLV
ACMVGVALAVAGTIFQGITRNPLADPGIIGINAGASLAAVTVIVLFPSAPIYTLPLSAFAGALLMAGLIYSLAWNNGSSP
VLFILMGVGLSAIAGAFTSLMITFGDIYSVSDALVWLAGSVYGRTWEQVFSFLPWLIVFVPMALTLARHLNTLNLGDDVA
KGLGTRVEWQRGLLVLVGVALAGAGVATAGMIGFVGLIAPHLGRQLVGTNHQGLLPTSALLGGMLVVVADFLGRTLFAPI
EIPCGVVTAAVGAPYFLYLLIRNRKK

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=46.0714285714286, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=35.7575757575758, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=38.2758620689655, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=35.5633802816901, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790741, Length=302, Percent_Identity=36.4238410596026, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786347, Length=276, Percent_Identity=34.7826086956522, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36511; Mature: 36511

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDWLVIRSETMSLRIDRRVPPILLCLVVAIVVAMVMNLGRGEYPIAPLDIIKTVLGID
CCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
TGNPDHAFVIYNLRLPRTLVACMVGVALAVAGTIFQGITRNPLADPGIIGINAGASLAAV
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHH
TVIVLFPSAPIYTLPLSAFAGALLMAGLIYSLAWNNGSSPVLFILMGVGLSAIAGAFTSL
HHHHEECCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MITFGDIYSVSDALVWLAGSVYGRTWEQVFSFLPWLIVFVPMALTLARHLNTLNLGDDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KGLGTRVEWQRGLLVLVGVALAGAGVATAGMIGFVGLIAPHLGRQLVGTNHQGLLPTSAL
HHCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHH
LGGMLVVVADFLGRTLFAPIEIPCGVVTAAVGAPYFLYLLIRNRKK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVDWLVIRSETMSLRIDRRVPPILLCLVVAIVVAMVMNLGRGEYPIAPLDIIKTVLGID
CCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
TGNPDHAFVIYNLRLPRTLVACMVGVALAVAGTIFQGITRNPLADPGIIGINAGASLAAV
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHH
TVIVLFPSAPIYTLPLSAFAGALLMAGLIYSLAWNNGSSPVLFILMGVGLSAIAGAFTSL
HHHHEECCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MITFGDIYSVSDALVWLAGSVYGRTWEQVFSFLPWLIVFVPMALTLARHLNTLNLGDDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KGLGTRVEWQRGLLVLVGVALAGAGVATAGMIGFVGLIAPHLGRQLVGTNHQGLLPTSAL
HHCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHH
LGGMLVVVADFLGRTLFAPIEIPCGVVTAAVGAPYFLYLLIRNRKK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]