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The map label for this gene is murQ [H]

Identifier: 17229924

GI number: 17229924

Start: 2924402

End: 2925325

Strand: Direct

Name: murQ [H]

Synonym: alr2432

Alternate gene names: 17229924

Gene position: 2924402-2925325 (Clockwise)

Preceding gene: 17229923

Following gene: 17229925

Centisome position: 45.6

GC content: 48.27

Gene sequence:

>924_bases
ATGGCAGATTTGCAGGAACGTGGACATTTATTGACGGAACAAGTCAATCCTTTGAGTCAGAACTTAGACCAACTCAGTTC
TCTGGAATTGGTGGAGTTGTTTAATAGTGAAGACCTCAAGACTGTGGAGGCAGTGGCGGCGGCTAAAGTCCAGATTGCAA
CAGCAATTGAGCAGACAGCCGATCGCCTGCGTCAGGGAGGACGCTTGTTTTATGTCGGTGCTGGAACCAGTGGTAGGTTG
GGTGTGTTAGATGCGGCTGAGTGTCCACCAACTTTTTGTACACCCCCAGAGTTGGTACAGGGGATTATCGCTGGTGGTGC
TGGCGCACTGGTACGCAGTTCGGAAGATTTAGAAGACCGGGCGGAAGATGGAGACGCAGCGATCGCTCAACGTCACATTA
CCCAATTAGATGTCGTCGTTGGGATTACGGCTGGTGGGACAACGCCTTTTGTCCAGGGTGCAATTAACTCTGCTCGTCAA
CGGGGAGCCTTGACAATTTTCATTGCTTGTGTTCCTGCTGAACAAGTGAGTTTTACAGCCGATATTGATATTCGTTTGTT
AACAGGGCCAGAAATATTGGCTGGTTCTACTCGCCTCAAAGCCGGTACAGTTACTAAATTAACGCTAAATATCCTCTCGA
CTGGGGTGATGGTCAAGCTGGGCAAAGTTTACGGTAATCGCATGGTGGATGTAGCAGTCACAAATCAGAAATTACGCGAT
CGCGCTTTGCGAATTTTGCAAGACCTCACCGGGTTAAGTCGGGAAGCGGCTGGTTTCTTATTAGAACGTAGTAGCAAATG
GGTCAAATTGGCGCTGGTGATGCACTGGACTGGTTTGGATAAAGACGCAGGCGATCGGCTTTTATCAGCACATCAAGGAA
ATCTGAGGGAAGCGGTTGCTAGTTATAAAAATCAAAATGATTAG

Upstream 100 bases:

>100_bases
TGTTGTAACTTAGTCGTTTAGTCATTAGAGACGTTTTATGAAACGTCTGTACATGGGGATTCTTGACTAAATTACATAAT
TGCAGGGGACATCAAAATAC

Downstream 100 bases:

>100_bases
TTAGTTGTCAGTTGTCATTAGTCAAAAATCTTGCAATGTTGACCGTTGACTGTTGACCGTTGATTTTTAAGTATATTCGG
TAATTTGTTGTCATCTACCA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MADLQERGHLLTEQVNPLSQNLDQLSSLELVELFNSEDLKTVEAVAAAKVQIATAIEQTADRLRQGGRLFYVGAGTSGRL
GVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDRAEDGDAAIAQRHITQLDVVVGITAGGTTPFVQGAINSARQ
RGALTIFIACVPAEQVSFTADIDIRLLTGPEILAGSTRLKAGTVTKLTLNILSTGVMVKLGKVYGNRMVDVAVTNQKLRD
RALRILQDLTGLSREAAGFLLERSSKWVKLALVMHWTGLDKDAGDRLLSAHQGNLREAVASYKNQND

Sequences:

>Translated_307_residues
MADLQERGHLLTEQVNPLSQNLDQLSSLELVELFNSEDLKTVEAVAAAKVQIATAIEQTADRLRQGGRLFYVGAGTSGRL
GVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDRAEDGDAAIAQRHITQLDVVVGITAGGTTPFVQGAINSARQ
RGALTIFIACVPAEQVSFTADIDIRLLTGPEILAGSTRLKAGTVTKLTLNILSTGVMVKLGKVYGNRMVDVAVTNQKLRD
RALRILQDLTGLSREAAGFLLERSSKWVKLALVMHWTGLDKDAGDRLLSAHQGNLREAVASYKNQND
>Mature_306_residues
ADLQERGHLLTEQVNPLSQNLDQLSSLELVELFNSEDLKTVEAVAAAKVQIATAIEQTADRLRQGGRLFYVGAGTSGRLG
VLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDRAEDGDAAIAQRHITQLDVVVGITAGGTTPFVQGAINSARQR
GALTIFIACVPAEQVSFTADIDIRLLTGPEILAGSTRLKAGTVTKLTLNILSTGVMVKLGKVYGNRMVDVAVTNQKLRDR
ALRILQDLTGLSREAAGFLLERSSKWVKLALVMHWTGLDKDAGDRLLSAHQGNLREAVASYKNQND

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=288, Percent_Identity=44.4444444444444, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32781; Mature: 32650

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLQERGHLLTEQVNPLSQNLDQLSSLELVELFNSEDLKTVEAVAAAKVQIATAIEQTA
CCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DRLRQGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDR
HHHHHCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHH
AEDGDAAIAQRHITQLDVVVGITAGGTTPFVQGAINSARQRGALTIFIACVPAEQVSFTA
HCCCHHHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECHHHEEEEE
DIDIRLLTGPEILAGSTRLKAGTVTKLTLNILSTGVMVKLGKVYGNRMVDVAVTNQKLRD
CEEEEEECCCCEECCCCEECCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEEEECCHHHHH
RALRILQDLTGLSREAAGFLLERSSKWVKLALVMHWTGLDKDAGDRLLSAHQGNLREAVA
HHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHHHCCCHHHHHHH
SYKNQND
HHCCCCC
>Mature Secondary Structure 
ADLQERGHLLTEQVNPLSQNLDQLSSLELVELFNSEDLKTVEAVAAAKVQIATAIEQTA
CCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DRLRQGGRLFYVGAGTSGRLGVLDAAECPPTFCTPPELVQGIIAGGAGALVRSSEDLEDR
HHHHHCCEEEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHH
AEDGDAAIAQRHITQLDVVVGITAGGTTPFVQGAINSARQRGALTIFIACVPAEQVSFTA
HCCCHHHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECHHHEEEEE
DIDIRLLTGPEILAGSTRLKAGTVTKLTLNILSTGVMVKLGKVYGNRMVDVAVTNQKLRD
CEEEEEECCCCEECCCCEECCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEEEECCHHHHH
RALRILQDLTGLSREAAGFLLERSSKWVKLALVMHWTGLDKDAGDRLLSAHQGNLREAVA
HHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHHHCCCHHHHHHH
SYKNQND
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA