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The map label for this gene is phoP [H]

Identifier: 17229921

GI number: 17229921

Start: 2916977

End: 2917360

Strand: Direct

Name: phoP [H]

Synonym: alr2429

Alternate gene names: 17229921

Gene position: 2916977-2917360 (Clockwise)

Preceding gene: 17229920

Following gene: 17229923

Centisome position: 45.48

GC content: 43.49

Gene sequence:

>384_bases
ATGAACAACAAACGAATTTTAGTTGTCGATAACGAGCAGTATATTCAAGAAGTTGCCAAAATTTGCTTGGAAACAGTTGC
GGGTTGGGAAGTTGTCACAGCCAGTTCAGGACAAGAAGGCATAAATAAAGCCGAGACTTACCAACCAGATGCAATTTTAC
TAGATGTGATGATGCCGGACATGGATGGAATCGCTACATTTGAGAAACTGCAAGCCAATTCCGTCACCAAAGAAATACCA
GTAATCTTATTAACCGCCAAAATCCAAGCCTCTGACCGTCGCCGTTACTCCCAATTGGGAATGGTGAGTGCGATCGCTAA
ACCCTTCAATCCGCTAGAATTAGCTGGTCAAGTAGCTACTGCCCTTGGTTGGAATTTAGCCTAA

Upstream 100 bases:

>100_bases
GGGGATTGGGGACTGGGGATTGGGGATTGGGGATGAAGGGGAAATCACTAATGACTAATGACTAATGACTAATGACTAAT
AACTAATAACTAACTTAACT

Downstream 100 bases:

>100_bases
AGTACTGATATCCAATTTTTACAATTACCCATTCTTAAAACCTGGTTTGATATTCAATTACTGCACGACTATCATCTTCT
AAATTAGTAGAAGCACGTAC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MNNKRILVVDNEQYIQEVAKICLETVAGWEVVTASSGQEGINKAETYQPDAILLDVMMPDMDGIATFEKLQANSVTKEIP
VILLTAKIQASDRRRYSQLGMVSAIAKPFNPLELAGQVATALGWNLA

Sequences:

>Translated_127_residues
MNNKRILVVDNEQYIQEVAKICLETVAGWEVVTASSGQEGINKAETYQPDAILLDVMMPDMDGIATFEKLQANSVTKEIP
VILLTAKIQASDRRRYSQLGMVSAIAKPFNPLELAGQVATALGWNLA
>Mature_127_residues
MNNKRILVVDNEQYIQEVAKICLETVAGWEVVTASSGQEGINKAETYQPDAILLDVMMPDMDGIATFEKLQANSVTKEIP
VILLTAKIQASDRRRYSQLGMVSAIAKPFNPLELAGQVATALGWNLA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=36.9747899159664, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1786911, Length=117, Percent_Identity=35.042735042735, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1788394, Length=121, Percent_Identity=31.404958677686, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI1790860, Length=122, Percent_Identity=31.1475409836066, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13893; Mature: 13893

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKRILVVDNEQYIQEVAKICLETVAGWEVVTASSGQEGINKAETYQPDAILLDVMMPD
CCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCC
MDGIATFEKLQANSVTKEIPVILLTAKIQASDRRRYSQLGMVSAIAKPFNPLELAGQVAT
CCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALGWNLA
HHCCCCC
>Mature Secondary Structure
MNNKRILVVDNEQYIQEVAKICLETVAGWEVVTASSGQEGINKAETYQPDAILLDVMMPD
CCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCC
MDGIATFEKLQANSVTKEIPVILLTAKIQASDRRRYSQLGMVSAIAKPFNPLELAGQVAT
CCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALGWNLA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]