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The map label for this gene is crp [C]

Identifier: 17229817

GI number: 17229817

Start: 2803092

End: 2803775

Strand: Direct

Name: crp [C]

Synonym: alr2325

Alternate gene names: 17229817

Gene position: 2803092-2803775 (Clockwise)

Preceding gene: 17229816

Following gene: 17229818

Centisome position: 43.7

GC content: 36.84

Gene sequence:

>684_bases
ATGCAAACTGAGGTTTTTAGTGATATTTTCCCCTTATTGAGTACAGCCACTCCACAAACCTTAGAATGGCTACTCAATAT
TGCAATTGATCATGAATATCCCACTGGTAGAGCAGTTTTAATGGAAGATGCCTGGGGTAATGCAGTTTATTTCGTTGTAT
CTGGATGGGTAAAAGTTCGGCGCACCTGTGGAGATGATTCGGTAGCTTTAGCAATTTTAGGAAGGGGTGATTTTTTTGGA
GAAATGGCGATTTTAGATGAATCTCCTCGCTCAACAGATGTAATTGCTCTTTCACCAGTCAAGTTACTCAGTATTTCTAG
AGAACGTTTTATTCAAATTTTATTTAAAGACCCACAATTGCATCATAGAATGCTGCAATTAATGGTGCGACGATTACGAC
AAATTAACCAACGGTTACAAATCCGTTCTTCACCACCTGCTGTGAAATTAGCTCATACCTTAGTTAGTTTGGGTGAGAGC
TATGGTCAAGAATCTACACAAGGTAGGGAAATTTTTAATATCCCTTTTAAGGACTTAGCAGAGGTTACAGAAATCGGTGT
TGAAGAAACTAGCAAAATTATGGATAAATTGCACGATAAAGGGTGGATAAAAATTGACAGTACTAATAATATTATCTATC
TGATAAATTTCAAACAATTGCTGAATTTAGCGGGAAAAGTCTAA

Upstream 100 bases:

>100_bases
CCCACTAACTTTTTTCTCATCTATTGCTATATTTCGACTTTAAAACTTATAGTAGATGGCTTAATTCTCAAATAACAAAC
TCATTTTTAGTAGATATTTC

Downstream 100 bases:

>100_bases
TAAAAGCATCCTCTTTTAAACTTTTTTTAAGTTTTTCCTCAGCACTAAAACACCTGATATTTGAGGGCTAACGTCTTCAT
GGAAGCATATTAAACAAACA

Product: transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator Crp/Fnr Family; Crp Family Transcriptional Regulator; Catabolite Gene Activator Protein; Regulatory Protein; CAMP Receptor Protein; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MQTEVFSDIFPLLSTATPQTLEWLLNIAIDHEYPTGRAVLMEDAWGNAVYFVVSGWVKVRRTCGDDSVALAILGRGDFFG
EMAILDESPRSTDVIALSPVKLLSISRERFIQILFKDPQLHHRMLQLMVRRLRQINQRLQIRSSPPAVKLAHTLVSLGES
YGQESTQGREIFNIPFKDLAEVTEIGVEETSKIMDKLHDKGWIKIDSTNNIIYLINFKQLLNLAGKV

Sequences:

>Translated_227_residues
MQTEVFSDIFPLLSTATPQTLEWLLNIAIDHEYPTGRAVLMEDAWGNAVYFVVSGWVKVRRTCGDDSVALAILGRGDFFG
EMAILDESPRSTDVIALSPVKLLSISRERFIQILFKDPQLHHRMLQLMVRRLRQINQRLQIRSSPPAVKLAHTLVSLGES
YGQESTQGREIFNIPFKDLAEVTEIGVEETSKIMDKLHDKGWIKIDSTNNIIYLINFKQLLNLAGKV
>Mature_227_residues
MQTEVFSDIFPLLSTATPQTLEWLLNIAIDHEYPTGRAVLMEDAWGNAVYFVVSGWVKVRRTCGDDSVALAILGRGDFFG
EMAILDESPRSTDVIALSPVKLLSISRERFIQILFKDPQLHHRMLQLMVRRLRQINQRLQIRSSPPAVKLAHTLVSLGES
YGQESTQGREIFNIPFKDLAEVTEIGVEETSKIMDKLHDKGWIKIDSTNNIIYLINFKQLLNLAGKV

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789756, Length=201, Percent_Identity=23.8805970149254, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25737; Mature: 25737

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEVFSDIFPLLSTATPQTLEWLLNIAIDHEYPTGRAVLMEDAWGNAVYFVVSGWVKVR
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHH
RTCGDDSVALAILGRGDFFGEMAILDESPRSTDVIALSPVKLLSISRERFIQILFKDPQL
HHCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCHH
HHRMLQLMVRRLRQINQRLQIRSSPPAVKLAHTLVSLGESYGQESTQGREIFNIPFKDLA
HHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHH
EVTEIGVEETSKIMDKLHDKGWIKIDSTNNIIYLINFKQLLNLAGKV
HHHHCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHHHHHHHCCC
>Mature Secondary Structure
MQTEVFSDIFPLLSTATPQTLEWLLNIAIDHEYPTGRAVLMEDAWGNAVYFVVSGWVKVR
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHH
RTCGDDSVALAILGRGDFFGEMAILDESPRSTDVIALSPVKLLSISRERFIQILFKDPQL
HHCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCHH
HHRMLQLMVRRLRQINQRLQIRSSPPAVKLAHTLVSLGESYGQESTQGREIFNIPFKDLA
HHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHH
EVTEIGVEETSKIMDKLHDKGWIKIDSTNNIIYLINFKQLLNLAGKV
HHHHCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA