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The map label for this gene is htpX [H]

Identifier: 17229755

GI number: 17229755

Start: 2722089

End: 2722958

Strand: Reverse

Name: htpX [H]

Synonym: all2263

Alternate gene names: 17229755

Gene position: 2722958-2722089 (Counterclockwise)

Preceding gene: 17229759

Following gene: 17229754

Centisome position: 42.45

GC content: 45.52

Gene sequence:

>870_bases
ATGGGAAATCAATTTAAAACGCTTGCTTTGCTTGCTGCCCTCAGTGGCTTACTAATTGCTATCAGTTATTGGGTAATTGG
CGGTAGTAGCGGCTTGATGATTGGTATTGGCTTGGCGGCAGTGACAAACCTGCTTTCATGGTATCAATCAGATAAGATTG
CCTTGGCAGTTTACCGCGCTCAAGCTGTGAGCGAAAGTCAAGCGCCAAAACTTTATCGCACGGTGCAGAGATTATCACAA
CGCGCTAATATTCCCATGCCAGGAGTGTATATTGTTCCAGGTCAAACTGCTAATGCTTTTGCGACAGGAAGAGATCCAGA
ACACGCGGCGGTGGCTGTCACCGAAGGTATTTTAAATATATTGCCAGAGGATGAATTAGAAGCTGTCATCGCCCACGAAC
TTACACATATTATTAACCGAGACACATTAACACAAGCTGTAGCTGCTACTGTTGCCGGTGCTATCTCTTTCTTGGCACAA
ATGGTGAGTTATAGCTTATGGTTCGGTGGGATAGGTGGACGAGATAACGAAAGAGGCGGAAATCCTTTAGGTGTTTTGTT
AACTGTTGTACTTGCACCTATAGCAGCCACTATCATTCAGCTAGCCATATCCCGCACTAGAGAATTTTCTGCTGATGCTG
GTTCTGCCAGATTAACAGGTAATCCCCGCGCCCTAGCCCGCGCATTACAAAGACTGGAAGCCACAGCGCGACAAATGCCC
TTAAATGCTAACCCAGCTTTTGAGCCGCTATTAATTATCAACCCCATTTCTGGGCAGTTTTTAGGTAACTTATTTTCCAG
CCATCCATCCACCGAAGCAAGAGTTCAAGCACTGCTGAAGTTAGAAAAACAACTGCCAACAATAGCTTAG

Upstream 100 bases:

>100_bases
ATCCCTGTTTAGATAGATAAAATCAAAGTGCAACTCAAGTAATCTAGTTGTCTATAAAAGATTAAAAAAATCAATACAGC
ATTAGCAGGAGAGCGCAAAT

Downstream 100 bases:

>100_bases
GTAGTAGATAACTATTGACTGTTAACTCATGACTCAAAGGATATTTCAACTATGAATGCTGACAACATCGAAATTATCGA
ATCTGTCGAAATTGTTGAAT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MGNQFKTLALLAALSGLLIAISYWVIGGSSGLMIGIGLAAVTNLLSWYQSDKIALAVYRAQAVSESQAPKLYRTVQRLSQ
RANIPMPGVYIVPGQTANAFATGRDPEHAAVAVTEGILNILPEDELEAVIAHELTHIINRDTLTQAVAATVAGAISFLAQ
MVSYSLWFGGIGGRDNERGGNPLGVLLTVVLAPIAATIIQLAISRTREFSADAGSARLTGNPRALARALQRLEATARQMP
LNANPAFEPLLIINPISGQFLGNLFSSHPSTEARVQALLKLEKQLPTIA

Sequences:

>Translated_289_residues
MGNQFKTLALLAALSGLLIAISYWVIGGSSGLMIGIGLAAVTNLLSWYQSDKIALAVYRAQAVSESQAPKLYRTVQRLSQ
RANIPMPGVYIVPGQTANAFATGRDPEHAAVAVTEGILNILPEDELEAVIAHELTHIINRDTLTQAVAATVAGAISFLAQ
MVSYSLWFGGIGGRDNERGGNPLGVLLTVVLAPIAATIIQLAISRTREFSADAGSARLTGNPRALARALQRLEATARQMP
LNANPAFEPLLIINPISGQFLGNLFSSHPSTEARVQALLKLEKQLPTIA
>Mature_288_residues
GNQFKTLALLAALSGLLIAISYWVIGGSSGLMIGIGLAAVTNLLSWYQSDKIALAVYRAQAVSESQAPKLYRTVQRLSQR
ANIPMPGVYIVPGQTANAFATGRDPEHAAVAVTEGILNILPEDELEAVIAHELTHIINRDTLTQAVAATVAGAISFLAQM
VSYSLWFGGIGGRDNERGGNPLGVLLTVVLAPIAATIIQLAISRTREFSADAGSARLTGNPRALARALQRLEATARQMPL
NANPAFEPLLIINPISGQFLGNLFSSHPSTEARVQALLKLEKQLPTIA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=260, Percent_Identity=37.3076923076923, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30639; Mature: 30508

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNQFKTLALLAALSGLLIAISYWVIGGSSGLMIGIGLAAVTNLLSWYQSDKIALAVYRA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
QAVSESQAPKLYRTVQRLSQRANIPMPGVYIVPGQTANAFATGRDPEHAAVAVTEGILNI
HHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
LPEDELEAVIAHELTHIINRDTLTQAVAATVAGAISFLAQMVSYSLWFGGIGGRDNERGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NPLGVLLTVVLAPIAATIIQLAISRTREFSADAGSARLTGNPRALARALQRLEATARQMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCC
LNANPAFEPLLIINPISGQFLGNLFSSHPSTEARVQALLKLEKQLPTIA
CCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GNQFKTLALLAALSGLLIAISYWVIGGSSGLMIGIGLAAVTNLLSWYQSDKIALAVYRA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
QAVSESQAPKLYRTVQRLSQRANIPMPGVYIVPGQTANAFATGRDPEHAAVAVTEGILNI
HHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
LPEDELEAVIAHELTHIINRDTLTQAVAATVAGAISFLAQMVSYSLWFGGIGGRDNERGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NPLGVLLTVVLAPIAATIIQLAISRTREFSADAGSARLTGNPRALARALQRLEATARQMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCC
LNANPAFEPLLIINPISGQFLGNLFSSHPSTEARVQALLKLEKQLPTIA
CCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA