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The map label for this gene is sigK [H]

Identifier: 17229685

GI number: 17229685

Start: 2636309

End: 2636914

Strand: Reverse

Name: sigK [H]

Synonym: all2193

Alternate gene names: 17229685

Gene position: 2636914-2636309 (Counterclockwise)

Preceding gene: 17229686

Following gene: 17229684

Centisome position: 41.11

GC content: 44.39

Gene sequence:

>606_bases
ATGGAGCCTAAACAATCCCAGTCGACTTTAACAGGGCTTACCGATGTGACGGATGAAGCTTTATTTGTGGGACTCAAAAA
TGGCGATTCGGCGGCATTAAGTGTTTTATTCAATCGTCATGGTCGCTTAGTTTATGGATTGGCTTTGAAAATTCTGGCTG
ATTCCCAAGAAGCAGAAGACTTAACCCAGGAAATTTTTCTCACACTGTGGCGCAAAGCATCCAGTAATCCTGATTGTCGC
TTTTTTGTGCGCTATTTGGTGACAATAACGCGATCGCGTGCCATCGACAAAATTCGCGCTCGCACTAGACAACTCAAACT
TGTGGAAAAGTGGGGACAAACCATGACAAATGAAGCCGCACCAGAGCCAACACCTGTTGAACAGGCGAGTTTTGCCGAGC
GATCGGGGCGCATTCACAACGCTTTAGCCCAACTACCCGAAAAACAACGCCAAGTAATCGAACTAGCTTATCACCAAGGA
TTAAGTCAGTCAGAAATTGCCAAACAAATTGATATCCCTCTAGGTACAGTCAAAACCTCTACCCGCCAAGGATTACTCAA
ACTTAAGCGCATCTTACTAGATTCTGATTTGTCAATCTATGAATAA

Upstream 100 bases:

>100_bases
TAAGCAAACATATCTCTATGTACGTTGTGGAGCGAGGTGATGACAGAAAAAGTATGCAAAACTGGCGACTGTATTAGTTT
AGATATGGGTTAAAAATCGC

Downstream 100 bases:

>100_bases
ATCTTTTGATCCCGAACATATCAAAAACTTAGCTGCGGGGTTTGTCGTCGATGATCTCACCCCTGAAGAAGCCCAAGAAT
TTCGGCTGTTACTTGATGAA

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MEPKQSQSTLTGLTDVTDEALFVGLKNGDSAALSVLFNRHGRLVYGLALKILADSQEAEDLTQEIFLTLWRKASSNPDCR
FFVRYLVTITRSRAIDKIRARTRQLKLVEKWGQTMTNEAAPEPTPVEQASFAERSGRIHNALAQLPEKQRQVIELAYHQG
LSQSEIAKQIDIPLGTVKTSTRQGLLKLKRILLDSDLSIYE

Sequences:

>Translated_201_residues
MEPKQSQSTLTGLTDVTDEALFVGLKNGDSAALSVLFNRHGRLVYGLALKILADSQEAEDLTQEIFLTLWRKASSNPDCR
FFVRYLVTITRSRAIDKIRARTRQLKLVEKWGQTMTNEAAPEPTPVEQASFAERSGRIHNALAQLPEKQRQVIELAYHQG
LSQSEIAKQIDIPLGTVKTSTRQGLLKLKRILLDSDLSIYE
>Mature_201_residues
MEPKQSQSTLTGLTDVTDEALFVGLKNGDSAALSVLFNRHGRLVYGLALKILADSQEAEDLTQEIFLTLWRKASSNPDCR
FFVRYLVTITRSRAIDKIRARTRQLKLVEKWGQTMTNEAAPEPTPVEQASFAERSGRIHNALAQLPEKQRQVIELAYHQG
LSQSEIAKQIDIPLGTVKTSTRQGLLKLKRILLDSDLSIYE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 22593; Mature: 22593

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKQSQSTLTGLTDVTDEALFVGLKNGDSAALSVLFNRHGRLVYGLALKILADSQEAED
CCCCCHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHH
LTQEIFLTLWRKASSNPDCRFFVRYLVTITRSRAIDKIRARTRQLKLVEKWGQTMTNEAA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEPTPVEQASFAERSGRIHNALAQLPEKQRQVIELAYHQGLSQSEIAKQIDIPLGTVKTS
CCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCH
TRQGLLKLKRILLDSDLSIYE
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEPKQSQSTLTGLTDVTDEALFVGLKNGDSAALSVLFNRHGRLVYGLALKILADSQEAED
CCCCCHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHH
LTQEIFLTLWRKASSNPDCRFFVRYLVTITRSRAIDKIRARTRQLKLVEKWGQTMTNEAA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEPTPVEQASFAERSGRIHNALAQLPEKQRQVIELAYHQGLSQSEIAKQIDIPLGTVKTS
CCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCH
TRQGLLKLKRILLDSDLSIYE
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]