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The map label for this gene is atoS [H]

Identifier: 17229615

GI number: 17229615

Start: 2541480

End: 2542862

Strand: Direct

Name: atoS [H]

Synonym: alr2123

Alternate gene names: 17229615

Gene position: 2541480-2542862 (Clockwise)

Preceding gene: 17229614

Following gene: 17229617

Centisome position: 39.63

GC content: 37.6

Gene sequence:

>1383_bases
ATGTCAGATTTTAGCAATGAATTGCATACACAGATTCAGTACAGTTTGATTGAGAAATTGTCTGAATCCGAACGGCGTTA
CCGGGAATTAGTGGATAGTCTGCGCGAAATTGTGTTTAAATGCGATCGCTTGGGTAATCTCAATTTCCTCAACCGAGCCT
GGACAAATACCCTTGGTTATGGGATAACAGATGCCATCGGTAGTGCTTTAAGCAATTTCATTGACTTGGATGATCAGTAC
TTGTGGTCAGAAACTCTAGAAAAATTACAAACCGGAGTAGAGGTTTGTCAAAAACTCCGCTTTTACCATCAAACTGGTGC
AATTGTTTGGTTGGAACTATCTGCTCAACCTCAAAGTGAAACAGAATTCTCTGGCTCACTGATCAATATTACTGATGTCT
ACGACGAGCTTCGCTTACGCAAACACGCAGAAGGATTACTGAAGCAAACAAATGAGGAATTGGAAGCTAGGGTAGAACAA
CGAAATATTGAGCTAATTCAAGCTAATCACGACCTAAAAGTTACCCTTGATAAACTCAAATATACTCAGGCTCAACTGGT
GCAAACTGAAAAAATGTCGAGTTTGGGGCAATTAGTTGCAGGGATTGCTCACGAAATTAATAATCCAGTTAACTTTATTT
ATGCTAATCTCACCCATGCATCTGAATATACACAAGTCTTATTAAAAATCTTACAACTTTACCAGCAAACCTATCCAGTT
CCCTCGCTGCACATTCAAAAAGCAATAGTAACCTGGGATTTGGACTTTATTAAAAAAGATTTGGGTAAGGTACTGGAGTC
GATGCAAGTTGGCAGCGAACGCATTAGAGAAATTGTGCTGTTACTGCGAAATTTTTCTCGGTTGGATGAAGCAGAAATCA
AAATTGTTGATATTCACGCAGGTATCAATCACACAATCACGTTTCTGCATCACCGCCTTCAAAATGAGTCTGCAAATAGG
GTAATTCAAATAATTAAAAACTATGGATTAATTCCCCAGGTAAAGTGCTATCCCGCGCACCTAAATCAAGTATTCATGAA
TATTTTAAATAATGCAATTTATGCTTTAGACGAGAAAATTACTGATTTCTCAATTATTCACAGTCCTCAATCTCAACCCT
TCGTTCCTACTATTTGGATTAAGACTGAGATCGTTGATGAAACTTGGCTTAATATTTGCATTAAAAACAATGGTGGGGGT
ATTCACGAATCGGTAATTTCCAAAATATTTGATCCGTTCTTTACAACAAAACCTGTTGGTAAGGGAACTGGACTTGGTTT
ATTTATTAGTTATCAGATTGTAGTAGAAATGCACCAAGGTAACTTAATATGTAACTCCAAAACAAGCCAAGAAACGGAAT
TTTGCATCCAAATTCCCATCTAA

Upstream 100 bases:

>100_bases
CGGTGTTTGAGCAAGAATTCTACCACACTCATGTCTTCCCCTTATACGCCGATACAATTAACCACACCGAGCTACTTCAG
CGTTTGACGAGTACAGTATA

Downstream 100 bases:

>100_bases
TAGAACTATTGCCTTTAAAAGGTTGACTAATGCTTATGTCTTGTTTGCTATGCACCATTGTTTGATTAGCATATACGTGA
AATGGCTTGTCGCTAGACCG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSDFSNELHTQIQYSLIEKLSESERRYRELVDSLREIVFKCDRLGNLNFLNRAWTNTLGYGITDAIGSALSNFIDLDDQY
LWSETLEKLQTGVEVCQKLRFYHQTGAIVWLELSAQPQSETEFSGSLINITDVYDELRLRKHAEGLLKQTNEELEARVEQ
RNIELIQANHDLKVTLDKLKYTQAQLVQTEKMSSLGQLVAGIAHEINNPVNFIYANLTHASEYTQVLLKILQLYQQTYPV
PSLHIQKAIVTWDLDFIKKDLGKVLESMQVGSERIREIVLLLRNFSRLDEAEIKIVDIHAGINHTITFLHHRLQNESANR
VIQIIKNYGLIPQVKCYPAHLNQVFMNILNNAIYALDEKITDFSIIHSPQSQPFVPTIWIKTEIVDETWLNICIKNNGGG
IHESVISKIFDPFFTTKPVGKGTGLGLFISYQIVVEMHQGNLICNSKTSQETEFCIQIPI

Sequences:

>Translated_460_residues
MSDFSNELHTQIQYSLIEKLSESERRYRELVDSLREIVFKCDRLGNLNFLNRAWTNTLGYGITDAIGSALSNFIDLDDQY
LWSETLEKLQTGVEVCQKLRFYHQTGAIVWLELSAQPQSETEFSGSLINITDVYDELRLRKHAEGLLKQTNEELEARVEQ
RNIELIQANHDLKVTLDKLKYTQAQLVQTEKMSSLGQLVAGIAHEINNPVNFIYANLTHASEYTQVLLKILQLYQQTYPV
PSLHIQKAIVTWDLDFIKKDLGKVLESMQVGSERIREIVLLLRNFSRLDEAEIKIVDIHAGINHTITFLHHRLQNESANR
VIQIIKNYGLIPQVKCYPAHLNQVFMNILNNAIYALDEKITDFSIIHSPQSQPFVPTIWIKTEIVDETWLNICIKNNGGG
IHESVISKIFDPFFTTKPVGKGTGLGLFISYQIVVEMHQGNLICNSKTSQETEFCIQIPI
>Mature_459_residues
SDFSNELHTQIQYSLIEKLSESERRYRELVDSLREIVFKCDRLGNLNFLNRAWTNTLGYGITDAIGSALSNFIDLDDQYL
WSETLEKLQTGVEVCQKLRFYHQTGAIVWLELSAQPQSETEFSGSLINITDVYDELRLRKHAEGLLKQTNEELEARVEQR
NIELIQANHDLKVTLDKLKYTQAQLVQTEKMSSLGQLVAGIAHEINNPVNFIYANLTHASEYTQVLLKILQLYQQTYPVP
SLHIQKAIVTWDLDFIKKDLGKVLESMQVGSERIREIVLLLRNFSRLDEAEIKIVDIHAGINHTITFLHHRLQNESANRV
IQIIKNYGLIPQVKCYPAHLNQVFMNILNNAIYALDEKITDFSIIHSPQSQPFVPTIWIKTEIVDETWLNICIKNNGGGI
HESVISKIFDPFFTTKPVGKGTGLGLFISYQIVVEMHQGNLICNSKTSQETEFCIQIPI

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=451, Percent_Identity=24.8337028824834, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=279, Percent_Identity=24.7311827956989, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52716; Mature: 52585

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFSNELHTQIQYSLIEKLSESERRYRELVDSLREIVFKCDRLGNLNFLNRAWTNTLGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
GITDAIGSALSNFIDLDDQYLWSETLEKLQTGVEVCQKLRFYHQTGAIVWLELSAQPQSE
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
TEFSGSLINITDVYDELRLRKHAEGLLKQTNEELEARVEQRNIELIQANHDLKVTLDKLK
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCEEEHHHHH
YTQAQLVQTEKMSSLGQLVAGIAHEINNPVNFIYANLTHASEYTQVLLKILQLYQQTYPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
PSLHIQKAIVTWDLDFIKKDLGKVLESMQVGSERIREIVLLLRNFSRLDEAEIKIVDIHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GINHTITFLHHRLQNESANRVIQIIKNYGLIPQVKCYPAHLNQVFMNILNNAIYALDEKI
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCC
TDFSIIHSPQSQPFVPTIWIKTEIVDETWLNICIKNNGGGIHESVISKIFDPFFTTKPVG
CCEEEEECCCCCCCCEEEEEEHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
KGTGLGLFISYQIVVEMHQGNLICNSKTSQETEFCIQIPI
CCCCCEEEEEEEEEEEEECCCEEECCCCCCCCCEEEECCC
>Mature Secondary Structure 
SDFSNELHTQIQYSLIEKLSESERRYRELVDSLREIVFKCDRLGNLNFLNRAWTNTLGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
GITDAIGSALSNFIDLDDQYLWSETLEKLQTGVEVCQKLRFYHQTGAIVWLELSAQPQSE
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
TEFSGSLINITDVYDELRLRKHAEGLLKQTNEELEARVEQRNIELIQANHDLKVTLDKLK
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCEEEHHHHH
YTQAQLVQTEKMSSLGQLVAGIAHEINNPVNFIYANLTHASEYTQVLLKILQLYQQTYPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCC
PSLHIQKAIVTWDLDFIKKDLGKVLESMQVGSERIREIVLLLRNFSRLDEAEIKIVDIHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GINHTITFLHHRLQNESANRVIQIIKNYGLIPQVKCYPAHLNQVFMNILNNAIYALDEKI
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCC
TDFSIIHSPQSQPFVPTIWIKTEIVDETWLNICIKNNGGGIHESVISKIFDPFFTTKPVG
CCEEEEECCCCCCCCEEEEEEHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
KGTGLGLFISYQIVVEMHQGNLICNSKTSQETEFCIQIPI
CCCCCEEEEEEEEEEEEECCCEEECCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]