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The map label for this gene is feoB [H]

Identifier: 17229611

GI number: 17229611

Start: 2537919

End: 2539382

Strand: Direct

Name: feoB [H]

Synonym: alr2119

Alternate gene names: 17229611

Gene position: 2537919-2539382 (Clockwise)

Preceding gene: 17229610

Following gene: 17229612

Centisome position: 39.57

GC content: 43.17

Gene sequence:

>1464_bases
ATGATTAGCCAAGTTATCTATCCAGAACCAATTGAAGCAGCGATCGCTCAATTAGAATCGTGGTGGCAGACATTGGGGAA
TCGCTATTTATTTCATAATTACTCACTATCACCTCGTAGCCTGGCTTTATTACTGTTACAGAAAGACCCAGGATTATGGC
AAATATTACAACAAGACCAAGAACAGTGTCGTCATCTGGAAGTTTTGATTACTGTTACCCAAAATCAACTTCATCAGCCT
TTGGGACTAGCGATCGCCAATACTCGTCAAAGTCAGGCTCGGACAATAGAAAGAGCAGTTTTGCATGAAGCCAGAGAAGC
GCGATCGTCAATTACAGAAACAATCCACAAACTCACAGTCAATCCTATTACTGGCTTCCCTATTCTTGTCGTTATTCTTT
ATTACGGAGTTTACAAATTTGTCGGTGAATTTGGTGCAGGGGAACTAGTGGATCGCATCGAAAGCTTTTTTGAATCACAA
ATTAACCCATTAGTCAACCAAGTCACGGCACAAATCATTCCCTGGCGACCAATTCAAGACTTGATTGCTCATGACTATGG
CATTATCACCTTGGGAATCCGTTATGCTACAGCGATCGTTTTACCTGTAGTTGCCACTTACTTCTTGATGTTCTCGTTAC
TAGAAGATAGCGGCTATCTCCCACGTTTATCTTTGATGCTGGATCGCTTATTCAAATCCGTTGGTTTATCTGGTCGTGCG
GTAATTCCGATGGTATTGGGCTTGGGGTGCGACACAATGGCAACAATAGTCACCCGCACCTTAGAAACCAGACGTGAACG
ATTAATTGCCACCTTTTTACTTTCCCTAGCCATACCTTGTGCAGCACAGTGGGGTGTAATTGTAGGACTACTGGCTCAAA
AACCAGCCGCCTTAATATTTTGGGGAGGCTTTATCACCGCCATCTTCCTAGTAGTTGGGTATCTCACCGCCAGATTGTTA
CCTGGGACTTCCGGCAGGTTTTACATGGAAATTCCCCCTTTACGTTTGCCCAAATTACGGAATGTGTTCACCAAAACCTG
GGTGCGGATGAAGTGGTATTTCTTAGAGGTATTACCCTTGTTTATCTGGGCATCTGTGTTGATTTGGGTGGGACGTTTAA
CCGGATTATTTGACGTAATTATTCGTGCAATTGAACCTCTCACCTTGGCTTTAGGAATGCCAAAACAAGCAGCGCCCATA
TTTCTCTATGGCTTCTTCCGTCGAGATTATGGTGCAGCCGGACTGTTTGATTTGCAGCAACAGGGAAGCTTGACAGGTAA
TCAATTAGTGATAGCTGCGATCGTTCTGACTTTATTTTTACCTTGTATTGCCCAATTGCAAATGCTGATTAAGGAACGGG
GAACTAAAACTACTTTGGCAATAGTACTGTTTATTTTTCCCTTCGCCTTCCTCATGGGATATGTCGTCAACCTCGGCTTA
ATATTATTCGGAGTGAACTTTTAA

Upstream 100 bases:

>100_bases
TTCAAAATTAGGGAAGCCAAACAGAATAAGGGTTTTAGATTGTGTATCTGTCGCATTTTTTTCAAATTGGCGTAAGTATT
TGAGATCAGGAGAAAAGGGC

Downstream 100 bases:

>100_bases
TATGAACGCCTTATCAACAGTTAAAGTCGGTCAACCACAAACGGTAGTAAGTTTACGAACTCAAGATCAGGCCGTACTAC
AAAAGCTGATGGCATTCGGG

Product: iron(II) transporter

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MISQVIYPEPIEAAIAQLESWWQTLGNRYLFHNYSLSPRSLALLLLQKDPGLWQILQQDQEQCRHLEVLITVTQNQLHQP
LGLAIANTRQSQARTIERAVLHEAREARSSITETIHKLTVNPITGFPILVVILYYGVYKFVGEFGAGELVDRIESFFESQ
INPLVNQVTAQIIPWRPIQDLIAHDYGIITLGIRYATAIVLPVVATYFLMFSLLEDSGYLPRLSLMLDRLFKSVGLSGRA
VIPMVLGLGCDTMATIVTRTLETRRERLIATFLLSLAIPCAAQWGVIVGLLAQKPAALIFWGGFITAIFLVVGYLTARLL
PGTSGRFYMEIPPLRLPKLRNVFTKTWVRMKWYFLEVLPLFIWASVLIWVGRLTGLFDVIIRAIEPLTLALGMPKQAAPI
FLYGFFRRDYGAAGLFDLQQQGSLTGNQLVIAAIVLTLFLPCIAQLQMLIKERGTKTTLAIVLFIFPFAFLMGYVVNLGL
ILFGVNF

Sequences:

>Translated_487_residues
MISQVIYPEPIEAAIAQLESWWQTLGNRYLFHNYSLSPRSLALLLLQKDPGLWQILQQDQEQCRHLEVLITVTQNQLHQP
LGLAIANTRQSQARTIERAVLHEAREARSSITETIHKLTVNPITGFPILVVILYYGVYKFVGEFGAGELVDRIESFFESQ
INPLVNQVTAQIIPWRPIQDLIAHDYGIITLGIRYATAIVLPVVATYFLMFSLLEDSGYLPRLSLMLDRLFKSVGLSGRA
VIPMVLGLGCDTMATIVTRTLETRRERLIATFLLSLAIPCAAQWGVIVGLLAQKPAALIFWGGFITAIFLVVGYLTARLL
PGTSGRFYMEIPPLRLPKLRNVFTKTWVRMKWYFLEVLPLFIWASVLIWVGRLTGLFDVIIRAIEPLTLALGMPKQAAPI
FLYGFFRRDYGAAGLFDLQQQGSLTGNQLVIAAIVLTLFLPCIAQLQMLIKERGTKTTLAIVLFIFPFAFLMGYVVNLGL
ILFGVNF
>Mature_487_residues
MISQVIYPEPIEAAIAQLESWWQTLGNRYLFHNYSLSPRSLALLLLQKDPGLWQILQQDQEQCRHLEVLITVTQNQLHQP
LGLAIANTRQSQARTIERAVLHEAREARSSITETIHKLTVNPITGFPILVVILYYGVYKFVGEFGAGELVDRIESFFESQ
INPLVNQVTAQIIPWRPIQDLIAHDYGIITLGIRYATAIVLPVVATYFLMFSLLEDSGYLPRLSLMLDRLFKSVGLSGRA
VIPMVLGLGCDTMATIVTRTLETRRERLIATFLLSLAIPCAAQWGVIVGLLAQKPAALIFWGGFITAIFLVVGYLTARLL
PGTSGRFYMEIPPLRLPKLRNVFTKTWVRMKWYFLEVLPLFIWASVLIWVGRLTGLFDVIIRAIEPLTLALGMPKQAAPI
FLYGFFRRDYGAAGLFDLQQQGSLTGNQLVIAAIVLTLFLPCIAQLQMLIKERGTKTTLAIVLFIFPFAFLMGYVVNLGL
ILFGVNF

Specific function: Fe(2+) uptake system, probably driven by GTP [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the feoB (TC 9.A.8) family [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=355, Percent_Identity=25.0704225352113, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate [H]

EC number: NA

Molecular weight: Translated: 54744; Mature: 54744

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQVIYPEPIEAAIAQLESWWQTLGNRYLFHNYSLSPRSLALLLLQKDPGLWQILQQDQ
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHEEEEEECCCCHHHHHHHHH
EQCRHLEVLITVTQNQLHQPLGLAIANTRQSQARTIERAVLHEAREARSSITETIHKLTV
HHHHHHHHHEEECHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPITGFPILVVILYYGVYKFVGEFGAGELVDRIESFFESQINPLVNQVTAQIIPWRPIQD
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LIAHDYGIITLGIRYATAIVLPVVATYFLMFSLLEDSGYLPRLSLMLDRLFKSVGLSGRA
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCH
VIPMVLGLGCDTMATIVTRTLETRRERLIATFLLSLAIPCAAQWGVIVGLLAQKPAALIF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WGGFITAIFLVVGYLTARLLPGTSGRFYMEIPPLRLPKLRNVFTKTWVRMKWYFLEVLPL
EHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIWASVLIWVGRLTGLFDVIIRAIEPLTLALGMPKQAAPIFLYGFFRRDYGAAGLFDLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
QGSLTGNQLVIAAIVLTLFLPCIAQLQMLIKERGTKTTLAIVLFIFPFAFLMGYVVNLGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILFGVNF
HHHCCCC
>Mature Secondary Structure
MISQVIYPEPIEAAIAQLESWWQTLGNRYLFHNYSLSPRSLALLLLQKDPGLWQILQQDQ
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHEEEEEECCCCHHHHHHHHH
EQCRHLEVLITVTQNQLHQPLGLAIANTRQSQARTIERAVLHEAREARSSITETIHKLTV
HHHHHHHHHEEECHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPITGFPILVVILYYGVYKFVGEFGAGELVDRIESFFESQINPLVNQVTAQIIPWRPIQD
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LIAHDYGIITLGIRYATAIVLPVVATYFLMFSLLEDSGYLPRLSLMLDRLFKSVGLSGRA
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCH
VIPMVLGLGCDTMATIVTRTLETRRERLIATFLLSLAIPCAAQWGVIVGLLAQKPAALIF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WGGFITAIFLVVGYLTARLLPGTSGRFYMEIPPLRLPKLRNVFTKTWVRMKWYFLEVLPL
EHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FIWASVLIWVGRLTGLFDVIIRAIEPLTLALGMPKQAAPIFLYGFFRRDYGAAGLFDLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
QGSLTGNQLVIAAIVLTLFLPCIAQLQMLIKERGTKTTLAIVLFIFPFAFLMGYVVNLGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILFGVNF
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA