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The map label for this gene is argJ

Identifier: 17229565

GI number: 17229565

Start: 2479892

End: 2481133

Strand: Direct

Name: argJ

Synonym: alr2073

Alternate gene names: 17229565

Gene position: 2479892-2481133 (Clockwise)

Preceding gene: 17229563

Following gene: 17229566

Centisome position: 38.67

GC content: 47.1

Gene sequence:

>1242_bases
ATGGCAGACTGGCAGGAAATTACTGGTGGAATTACAGCACCAAAAGGTTATCGGGCGGCGGGAATTACAGCAGGACTCAA
ACCTTCGGGGTTGCCAGATTTAGCTTTGATAGTATCAGATGTAGAAGCGATCGCATCTGGTGTATTCACAACCAGTCAAG
TAAAGGCTGCTTGTGTAGACTACTGTCGGCAACGTTTACAAGCCAAGCAAAGCGCTCGCGCCATTCTTTGCAATGCTGGA
CAAGCCAACGCCGCTACAGGTAGTCAAGGTATTAAGGATGCAGAAGAAAGTGCCGAGTTGTTAGCAAAAGAGTTAAATAT
ATCCCCCGAATTAATTCTGTTGGCTTCCACGGGGGTAATTGGTCAACGAATTAAAATGGATGCCTTACGCAACGGTATTC
CTAAACTAATAGCATCCCTTACAGATACAGGTTCAGATGCAGCCGCCGGGGCAATTATCACTACAGATTTAGTCACAAAA
TCTATTGCTTTAGAAACAACTATAGGCGATCGTCCAGTCCGCATTGGTGGTATCGCCAAAGGTTCAGGGATGATTCATCC
CAACATGGCGACAATGCTAGCTTTTGTTACCTGTGATGCCGCAGTTTCCTCCCATCTTTGGCAACAAATGTTAACTAGGG
CAGCAGATAGAAGCTTCAATTCCATTACAGTAGATGGAGATACCAGTACCAACGATAGTTTAATCGCCCTAGCCAATGGA
CAGTCTCGCACCCCAGCCATTACTGAAGTCGGTGCAGAATCGGAAAAATTAGAGGCCATGCTAACAGCAGTATGCCAGCA
TTTAGCCAAAGCGATCGCCCGTGATGGCGAAGGTGCAACCTGTCTTATAGAAGTGCAAGTCACAGGCGCACATGATGAAC
AAGCAGCTAGACAAATCGCCAAAACTATTGCCGGTTCATCATTAGTGAAGTCTGCAATCTTTGGTCGTGACCCCAATTGG
GGGCGCATCGCCGCCGCCGCCGGACGTGCTGGTGTTCCCTTCGAGCAGGAAAATCTGCAAATTCAGCTAGGAGATTTTTT
ACTCTTAGACAATGGTCAACCCCTCCCATTTGACCGCGCCGCCGCCAGCGCGTATTTAAAACAAGCCGCCACAGGTGCTT
ATCTTCAGCAAGATACAGTCTTAATTTCTGTCAAGGTCGGTAATGGTCATGGCACTGGCAAAGCTTGGGGATGCGATTTA
AGTTATGACTATGTGAAGATTAACGCTGAGTATACAACTTAA

Upstream 100 bases:

>100_bases
AGAATTACGAATTACAAATTACGAATTACAAATTGCAAATTGCGAATTGATATAATCGCCAGTCAAGCCACTAAATTTCG
TTGTAGGGGTAAAAATAAAG

Downstream 100 bases:

>100_bases
GAATGAGGGTAATTGGTAATGGGTAATTTTCTGTAGGATGGAAGATGAAAAGCCATCACTTACGATGGACGGAACTCCAT
CGCTCATTACCAACAATGCA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIASGVFTTSQVKAACVDYCRQRLQAKQSARAILCNAG
QANAATGSQGIKDAEESAELLAKELNISPELILLASTGVIGQRIKMDALRNGIPKLIASLTDTGSDAAAGAIITTDLVTK
SIALETTIGDRPVRIGGIAKGSGMIHPNMATMLAFVTCDAAVSSHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAIARDGEGATCLIEVQVTGAHDEQAARQIAKTIAGSSLVKSAIFGRDPNW
GRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRAAASAYLKQAATGAYLQQDTVLISVKVGNGHGTGKAWGCDL
SYDYVKINAEYTT

Sequences:

>Translated_413_residues
MADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIASGVFTTSQVKAACVDYCRQRLQAKQSARAILCNAG
QANAATGSQGIKDAEESAELLAKELNISPELILLASTGVIGQRIKMDALRNGIPKLIASLTDTGSDAAAGAIITTDLVTK
SIALETTIGDRPVRIGGIAKGSGMIHPNMATMLAFVTCDAAVSSHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAIARDGEGATCLIEVQVTGAHDEQAARQIAKTIAGSSLVKSAIFGRDPNW
GRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRAAASAYLKQAATGAYLQQDTVLISVKVGNGHGTGKAWGCDL
SYDYVKINAEYTT
>Mature_412_residues
ADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIASGVFTTSQVKAACVDYCRQRLQAKQSARAILCNAGQ
ANAATGSQGIKDAEESAELLAKELNISPELILLASTGVIGQRIKMDALRNGIPKLIASLTDTGSDAAAGAIITTDLVTKS
IALETTIGDRPVRIGGIAKGSGMIHPNMATMLAFVTCDAAVSSHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANGQ
SRTPAITEVGAESEKLEAMLTAVCQHLAKAIARDGEGATCLIEVQVTGAHDEQAARQIAKTIAGSSLVKSAIFGRDPNWG
RIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRAAASAYLKQAATGAYLQQDTVLISVKVGNGHGTGKAWGCDLS
YDYVKINAEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=417, Percent_Identity=36.6906474820144, Blast_Score=236, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ1_NOSS1 (Q8YVA8)

Other databases:

- EMBL:   BA000019
- PIR:   AC2065
- RefSeq:   NP_486113.1
- ProteinModelPortal:   Q8YVA8
- SMR:   Q8YVA8
- STRING:   Q8YVA8
- MEROPS:   T05.001
- GeneID:   1105668
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr2073
- NMPDR:   fig|103690.1.peg.2380
- eggNOG:   COG1364
- HOGENOM:   HBG284202
- OMA:   VHENSAY
- PhylomeDB:   Q8YVA8
- ProtClustDB:   PRK05388
- BioCyc:   NSP103690:ALR2073-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 42998; Mature: 42867

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIASGVFTTSQVKAACVD
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YCRQRLQAKQSARAILCNAGQANAATGSQGIKDAEESAELLAKELNISPELILLASTGVI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
GQRIKMDALRNGIPKLIASLTDTGSDAAAGAIITTDLVTKSIALETTIGDRPVRIGGIAK
HHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCEEEHHHHHHHHEEEECCCCCCEEEECEEC
GSGMIHPNMATMLAFVTCDAAVSSHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECC
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAIARDGEGATCLIEVQVTGAHDEQAARQIA
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHH
KTIAGSSLVKSAIFGRDPNWGRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRA
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEECCEEEECCCCCCCHHHH
AASAYLKQAATGAYLQQDTVLISVKVGNGHGTGKAWGCDLSYDYVKINAEYTT
HHHHHHHHHHCCCEEECCEEEEEEEECCCCCCCCEEECCCCEEEEEEEEEECC
>Mature Secondary Structure 
ADWQEITGGITAPKGYRAAGITAGLKPSGLPDLALIVSDVEAIASGVFTTSQVKAACVD
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YCRQRLQAKQSARAILCNAGQANAATGSQGIKDAEESAELLAKELNISPELILLASTGVI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
GQRIKMDALRNGIPKLIASLTDTGSDAAAGAIITTDLVTKSIALETTIGDRPVRIGGIAK
HHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCEEEHHHHHHHHEEEECCCCCCEEEECEEC
GSGMIHPNMATMLAFVTCDAAVSSHLWQQMLTRAADRSFNSITVDGDTSTNDSLIALANG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECC
QSRTPAITEVGAESEKLEAMLTAVCQHLAKAIARDGEGATCLIEVQVTGAHDEQAARQIA
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHH
KTIAGSSLVKSAIFGRDPNWGRIAAAAGRAGVPFEQENLQIQLGDFLLLDNGQPLPFDRA
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCEEEECCEEEECCCCCCCHHHH
AASAYLKQAATGAYLQQDTVLISVKVGNGHGTGKAWGCDLSYDYVKINAEYTT
HHHHHHHHHHCCCEEECCEEEEEEEECCCCCCCCEEECCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840