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The map label for this gene is yafV [C]

Identifier: 17229493

GI number: 17229493

Start: 2394000

End: 2394815

Strand: Direct

Name: yafV [C]

Synonym: alr2001

Alternate gene names: 17229493

Gene position: 2394000-2394815 (Clockwise)

Preceding gene: 17229491

Following gene: 17229501

Centisome position: 37.33

GC content: 46.45

Gene sequence:

>816_bases
ATGAAGTCTTATTTAGCTGCCGCTATTCAAATGACCAGTGTGCCTGATTTACACAAGAATTTGGCACAAGCAGAAGAATT
AATTGATCTGGCGGTGCGTCGGGGTGCTGAGTTAGTGGGTTTGCCAGAAAATTTTTCCTTTATGGGTGAAGAACAGGATA
AACTGGCTCAAGCAGAAGCGATCGCTCGTGAAAGTGAGATTTTTATTAAAACGATGGCGCAGCGCTACCAAGTGACTCTT
TTGGGTGGTAGTTTCCCCGTACCGGTAAGTGATACAGGTAGAGTCTATAACACCACCATTCTCATCAGTCCCAGTGGTGA
AGAACTTGCTCGCTACAATAAAGTACACCTTTTTGATGTCAATGTTCCTGATGGTAATACCTACCGCGAATCTAGTACTG
TTGTCGCCGGTCAGCAATTACCCCCCGTCCATTTTTCGGAATATCTAGGCAATATCGGCGTTTCTATTTGCTACGATGTC
CGCTTCCCGGAACTCTACCGCCATCTCTCAGACAAGGGAACAGATATTATTTTTATACCTGCTGCTTTCACTGCTTTTAC
AGGCAAAGACCACTGGCAAGTTTTACTGCAAGCCAGAGCTATTGAAAATACCGCCTATGTAATTGCACCTGCTCAAACAG
GTAATAACTACGGTCGCCGCCTCACCCACGGACACGCTGTGGTTATCGACCCCTGGGGAACGATTTTAGCTGATGCCGGT
GACAAACCAGGAATTGCGATCGCGGAAATCAACCCTTCACGCCTAGAACAAGTCCGCCGCCAAATGCCTTCCTTGCAACA
TCGTGTATTTAGCTAA

Upstream 100 bases:

>100_bases
CCCAGTCCCTAATCCCTAGTCCCCAACCCCTACTCCCAGTCACCAACTAACGGTATATTTAAGTATCTATCTCACACAAC
TCTACTGTTTTTTTAAGTCT

Downstream 100 bases:

>100_bases
TTTTAGAAGTTAGGGGTTAGGGGTTAGAGGCTTTAACAATTCAAAATAGCCTACGGCTACTCCTGCGGAGAACTCGCAGA
GTAGGCTGCGCCAACAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKSYLAAAIQMTSVPDLHKNLAQAEELIDLAVRRGAELVGLPENFSFMGEEQDKLAQAEAIARESEIFIKTMAQRYQVTL
LGGSFPVPVSDTGRVYNTTILISPSGEELARYNKVHLFDVNVPDGNTYRESSTVVAGQQLPPVHFSEYLGNIGVSICYDV
RFPELYRHLSDKGTDIIFIPAAFTAFTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVVIDPWGTILADAG
DKPGIAIAEINPSRLEQVRRQMPSLQHRVFS

Sequences:

>Translated_271_residues
MKSYLAAAIQMTSVPDLHKNLAQAEELIDLAVRRGAELVGLPENFSFMGEEQDKLAQAEAIARESEIFIKTMAQRYQVTL
LGGSFPVPVSDTGRVYNTTILISPSGEELARYNKVHLFDVNVPDGNTYRESSTVVAGQQLPPVHFSEYLGNIGVSICYDV
RFPELYRHLSDKGTDIIFIPAAFTAFTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVVIDPWGTILADAG
DKPGIAIAEINPSRLEQVRRQMPSLQHRVFS
>Mature_271_residues
MKSYLAAAIQMTSVPDLHKNLAQAEELIDLAVRRGAELVGLPENFSFMGEEQDKLAQAEAIARESEIFIKTMAQRYQVTL
LGGSFPVPVSDTGRVYNTTILISPSGEELARYNKVHLFDVNVPDGNTYRESSTVVAGQQLPPVHFSEYLGNIGVSICYDV
RFPELYRHLSDKGTDIIFIPAAFTAFTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVVIDPWGTILADAG
DKPGIAIAEINPSRLEQVRRQMPSLQHRVFS

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=269, Percent_Identity=38.6617100371747, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI297632348, Length=269, Percent_Identity=38.6617100371747, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI5031947, Length=269, Percent_Identity=38.6617100371747, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI9910460, Length=268, Percent_Identity=33.2089552238806, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI297632346, Length=194, Percent_Identity=35.0515463917526, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI1786412, Length=238, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17556280, Length=269, Percent_Identity=39.0334572490706, Blast_Score=191, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6323383, Length=271, Percent_Identity=33.9483394833948, Blast_Score=162, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6322335, Length=297, Percent_Identity=32.3232323232323, Blast_Score=161, Evalue=9e-41,
Organism=Drosophila melanogaster, GI17933642, Length=281, Percent_Identity=35.9430604982206, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21355835, Length=269, Percent_Identity=30.1115241635688, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29966; Mature: 29966

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYLAAAIQMTSVPDLHKNLAQAEELIDLAVRRGAELVGLPENFSFMGEEQDKLAQAEA
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHH
IARESEIFIKTMAQRYQVTLLGGSFPVPVSDTGRVYNTTILISPSGEELARYNKVHLFDV
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEEEEECCCCHHHHHCCEEEEEEE
NVPDGNTYRESSTVVAGQQLPPVHFSEYLGNIGVSICYDVRFPELYRHLSDKGTDIIFIP
ECCCCCCCCCCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEEC
AAFTAFTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVVIDPWGTILADAG
CEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCEEEECCCHHEEECCC
DKPGIAIAEINPSRLEQVRRQMPSLQHRVFS
CCCCEEEEECCHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MKSYLAAAIQMTSVPDLHKNLAQAEELIDLAVRRGAELVGLPENFSFMGEEQDKLAQAEA
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHH
IARESEIFIKTMAQRYQVTLLGGSFPVPVSDTGRVYNTTILISPSGEELARYNKVHLFDV
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEEEEEEECCCCHHHHHCCEEEEEEE
NVPDGNTYRESSTVVAGQQLPPVHFSEYLGNIGVSICYDVRFPELYRHLSDKGTDIIFIP
ECCCCCCCCCCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEEC
AAFTAFTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVVIDPWGTILADAG
CEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCEEEECCCHHEEECCC
DKPGIAIAEINPSRLEQVRRQMPSLQHRVFS
CCCCEEEEECCHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]