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The map label for this gene is atoS [C]

Identifier: 17229460

GI number: 17229460

Start: 2351722

End: 2354001

Strand: Direct

Name: atoS [C]

Synonym: alr1968

Alternate gene names: 17229460

Gene position: 2351722-2354001 (Clockwise)

Preceding gene: 17229459

Following gene: 17229468

Centisome position: 36.67

GC content: 40.92

Gene sequence:

>2280_bases
ATGGCAGATGAAATTATCAAAGTCTTATTGGTAGAAGATAATCCTGGTGACGCTTTTTTAATTCAAGAGTTAATCAAAGA
GGTAAATACAGCCAATTTAGAGTTATATCCAGTAGAGCGATTATCGGAAGCACTGAAAATTCTTGCTAGTGATACTTCTG
ATGGTTCGGTTCCACGCTTTGATGTCATGTTATTAGACTTGTCTTTACCCGACAGTCAGGGTATAGATACCTTTGTCAGA
GCTAACCGTGAGACCAACGTTCTTCCCATCATCGTGCTAACGGGAATAGATGATGAGAATTTAGCACTCAAAGCCATGCA
GAAGGGAGCGCAAGATTATTTAGTTAAAGGACAAGTCACAGGAGACTTATTAGTACGTTCCATTCGTTATGCCATAGAAC
GTCAACGAGTAGAAGAAGCTCTGCGTCACAGCGAGGAACGGTTTCGGGTGGCGCTGAAAAACTCTCCTATTTTCGTTTTT
AATCAAGACAGAGACTTACGTTATACCTGGATTTATAACCCAATTGCTGGGTGGACAGTTGAAGAAATGTTGGGTAAACA
AGACTCGGAAATTATGTCTGAGCAGGATGCCCAATGTCTCACTGCCATCAAATATCATGTCCTCACTACAGGTATAGGGA
CTCGTCAGGTGGTGTCTATCGGTACTCCTCTAGGGACAAAATACTATGATTTAACTGTCGAGCCATTGCGGAATGAGTCA
CAAGACATTGTTGGCATTACTTGTGCTTGTATTGACATTAGTGAACGTAAACTAGCAGAAGCTAAAATTCGTGAACAAGC
AGCCTTATTAGACATCACCACAGATGGTATATGTGTGCGCGATTTAGAAAATAAAATTTTGTTTTGGAACAAAGGTGCAG
AAAATCTCTACGGTTGGCAAGCCCATGAGGTGATAGGTAAAAATGCTAGTGATCTTTTATTTCGTGAACCTTCTCTAGAA
GTGGAAACTGCTTTATTAAACGTTATCTCTCAAGGTAATTGGCAAGGAGAATTAAACAAAGTTACCAAAACTGGTAAGGA
AATTGTTGTGGCTAGTCGTTGGAGTTTAGTCTATGACGAGCAAGGAAAACCAAAATCCATTCTCTCTGTAGATACAGATA
TTACCCAGAAAAAACATTTAGAAGCGCAATTATTTCGGACTCAACGCCTAGAAAGTATCGGAACTCTAGCTAGTGGCATT
GCTCACGACCTCAACAATATCTTGACACCAATTTTAGCAGGAGCGCAATTACTACCACTCAAATTTCCTGACGCAGATGA
ACGTACTCAGCATTTACTAGAGATTTTAGAAATCAATGCTAAACGTGGTGCTGATTTAGTGAAGCAAGTGCTGTCCTTCG
CCAGAGGTGTGGAAGGAAAGCGCATCACTTTACAACTCAAACATTTAATTGTGGAAGTTGTGAAAATTTTGAAGGAAACA
TTTCCCAAATCCATCGAAGTTTACACAGATATACCAAATGACTTGTGGATGGTTTCTGGGGATAGTACCCAACTTCATCA
AGTGCTGATGAATCTTTGCGTCAATGCCCGCGATGCTATGCCTGATGGTGGTACGTTGACAATCTCTGCGGAAAATCTAT
TGATTGATGAAAACTACGCCCGGATGAACTTGGAAGCTAAACAAGGCCCATACATCATGATTACGGTGTCGGATACAGGA
GTGGGCATTTCTCCAGAAAACTTAGATAGGATATTTGAGCCATTTTTTACCACCAAAGCTGTAGGACAAGGTACTGGTTT
AGGTCTTTCCACGGTTTTAGGGATTGTCAAAAGTCACGGTGGTTTCGTCAATGTCTATAGTGAAGAAGGGCGGGGTACTA
CCTTTAGAGTTTACTTACCATCTGTGGGTGGTACGGAAGCACCCCATATAGATCATCTATTACCGCCGGCTGGTCATGGA
GAATTAATCTTGATTGTTGATGATGAAGTCTCAATCCAAGATATTACCAAAACATCTTTAGAAGGTCATCAATATGAGAC
TTTAGTTGCTAGTGATGGGGTGGAGGCGATCGCTCTTTATGCCAAAAATGCCGATAAAATTAGTGCTGTATTAATGGATA
TCATGCTACCAGTACTCGATGGCTTAACCACTATTCGCACTTTGAAGAAAATTAACCCCCAAGTCAAAATTATAGCTACC
AGTGGACTCATATCGAAAACTAAGTTAACCGAAATAGTCAATACTGGTGCTAACTCATTCTTAGCCAAGCCCTACACAGT
CAATGAGTTGTTGTTGGCTCTGCACGAAGTGATGACGTGA

Upstream 100 bases:

>100_bases
TACATAACTAAGCCTGTTGACTTTGACCAGTTCGTTAGAATTGTACAGTCCATAGAAAACTTTTGGTTTGCGATCGTCAA
GCTGCCACCGGAGTGAAGCA

Downstream 100 bases:

>100_bases
AATATTAAATCAAATTTCTATGCCTAAAACACATAAATGATCTTTTATAAGTTGTTTACCCAAATGCAAGGGATATGGTG
AGATAATATTACCCATAGAC

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MADEIIKVLLVEDNPGDAFLIQELIKEVNTANLELYPVERLSEALKILASDTSDGSVPRFDVMLLDLSLPDSQGIDTFVR
ANRETNVLPIIVLTGIDDENLALKAMQKGAQDYLVKGQVTGDLLVRSIRYAIERQRVEEALRHSEERFRVALKNSPIFVF
NQDRDLRYTWIYNPIAGWTVEEMLGKQDSEIMSEQDAQCLTAIKYHVLTTGIGTRQVVSIGTPLGTKYYDLTVEPLRNES
QDIVGITCACIDISERKLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQAHEVIGKNASDLLFREPSLE
VETALLNVISQGNWQGELNKVTKTGKEIVVASRWSLVYDEQGKPKSILSVDTDITQKKHLEAQLFRTQRLESIGTLASGI
AHDLNNILTPILAGAQLLPLKFPDADERTQHLLEILEINAKRGADLVKQVLSFARGVEGKRITLQLKHLIVEVVKILKET
FPKSIEVYTDIPNDLWMVSGDSTQLHQVLMNLCVNARDAMPDGGTLTISAENLLIDENYARMNLEAKQGPYIMITVSDTG
VGISPENLDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHGGFVNVYSEEGRGTTFRVYLPSVGGTEAPHIDHLLPPAGHG
ELILIVDDEVSIQDITKTSLEGHQYETLVASDGVEAIALYAKNADKISAVLMDIMLPVLDGLTTIRTLKKINPQVKIIAT
SGLISKTKLTEIVNTGANSFLAKPYTVNELLLALHEVMT

Sequences:

>Translated_759_residues
MADEIIKVLLVEDNPGDAFLIQELIKEVNTANLELYPVERLSEALKILASDTSDGSVPRFDVMLLDLSLPDSQGIDTFVR
ANRETNVLPIIVLTGIDDENLALKAMQKGAQDYLVKGQVTGDLLVRSIRYAIERQRVEEALRHSEERFRVALKNSPIFVF
NQDRDLRYTWIYNPIAGWTVEEMLGKQDSEIMSEQDAQCLTAIKYHVLTTGIGTRQVVSIGTPLGTKYYDLTVEPLRNES
QDIVGITCACIDISERKLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQAHEVIGKNASDLLFREPSLE
VETALLNVISQGNWQGELNKVTKTGKEIVVASRWSLVYDEQGKPKSILSVDTDITQKKHLEAQLFRTQRLESIGTLASGI
AHDLNNILTPILAGAQLLPLKFPDADERTQHLLEILEINAKRGADLVKQVLSFARGVEGKRITLQLKHLIVEVVKILKET
FPKSIEVYTDIPNDLWMVSGDSTQLHQVLMNLCVNARDAMPDGGTLTISAENLLIDENYARMNLEAKQGPYIMITVSDTG
VGISPENLDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHGGFVNVYSEEGRGTTFRVYLPSVGGTEAPHIDHLLPPAGHG
ELILIVDDEVSIQDITKTSLEGHQYETLVASDGVEAIALYAKNADKISAVLMDIMLPVLDGLTTIRTLKKINPQVKIIAT
SGLISKTKLTEIVNTGANSFLAKPYTVNELLLALHEVMT
>Mature_758_residues
ADEIIKVLLVEDNPGDAFLIQELIKEVNTANLELYPVERLSEALKILASDTSDGSVPRFDVMLLDLSLPDSQGIDTFVRA
NRETNVLPIIVLTGIDDENLALKAMQKGAQDYLVKGQVTGDLLVRSIRYAIERQRVEEALRHSEERFRVALKNSPIFVFN
QDRDLRYTWIYNPIAGWTVEEMLGKQDSEIMSEQDAQCLTAIKYHVLTTGIGTRQVVSIGTPLGTKYYDLTVEPLRNESQ
DIVGITCACIDISERKLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQAHEVIGKNASDLLFREPSLEV
ETALLNVISQGNWQGELNKVTKTGKEIVVASRWSLVYDEQGKPKSILSVDTDITQKKHLEAQLFRTQRLESIGTLASGIA
HDLNNILTPILAGAQLLPLKFPDADERTQHLLEILEINAKRGADLVKQVLSFARGVEGKRITLQLKHLIVEVVKILKETF
PKSIEVYTDIPNDLWMVSGDSTQLHQVLMNLCVNARDAMPDGGTLTISAENLLIDENYARMNLEAKQGPYIMITVSDTGV
GISPENLDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHGGFVNVYSEEGRGTTFRVYLPSVGGTEAPHIDHLLPPAGHGE
LILIVDDEVSIQDITKTSLEGHQYETLVASDGVEAIALYAKNADKISAVLMDIMLPVLDGLTTIRTLKKINPQVKIIATS
GLISKTKLTEIVNTGANSFLAKPYTVNELLLALHEVMT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=377, Percent_Identity=27.3209549071618, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=30.6451612903226, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI48994928, Length=530, Percent_Identity=23.5849056603774, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=29.6, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=271, Percent_Identity=25.0922509225092, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=272, Percent_Identity=28.3088235294118, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=354, Percent_Identity=25.7062146892655, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=287, Percent_Identity=24.7386759581882, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=25.9398496240602, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=26.9076305220884, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=25.8964143426295, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83867; Mature: 83736

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEIIKVLLVEDNPGDAFLIQELIKEVNTANLELYPVERLSEALKILASDTSDGSVPRF
CCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCEE
DVMLLDLSLPDSQGIDTFVRANRETNVLPIIVLTGIDDENLALKAMQKGAQDYLVKGQVT
EEEEEEEECCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHCCCHHEEEECCCH
GDLLVRSIRYAIERQRVEEALRHSEERFRVALKNSPIFVFNQDRDLRYTWIYNPIAGWTV
HHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCEEEEECCCCEEEEEEECCCCCCCH
EEMLGKQDSEIMSEQDAQCLTAIKYHVLTTGIGTRQVVSIGTPLGTKYYDLTVEPLRNES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCC
QDIVGITCACIDISERKLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQ
CCEEEEEEEEEECCHHHHHHHHHHHHHEEEEECCCCEEEEECCCCEEEEECCCCCCCCCC
AHEVIGKNASDLLFREPSLEVETALLNVISQGNWQGELNKVTKTGKEIVVASRWSLVYDE
HHHHHCCCCHHHEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECEEEEECC
QGKPKSILSVDTDITQKKHLEAQLFRTQRLESIGTLASGIAHDLNNILTPILAGAQLLPL
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
KFPDADERTQHLLEILEINAKRGADLVKQVLSFARGVEGKRITLQLKHLIVEVVKILKET
ECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHH
FPKSIEVYTDIPNDLWMVSGDSTQLHQVLMNLCVNARDAMPDGGTLTISAENLLIDENYA
CCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECEEEEECCCE
RMNLEAKQGPYIMITVSDTGVGISPENLDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHG
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
GFVNVYSEEGRGTTFRVYLPSVGGTEAPHIDHLLPPAGHGELILIVDDEVSIQDITKTSL
CEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHC
EGHQYETLVASDGVEAIALYAKNADKISAVLMDIMLPVLDGLTTIRTLKKINPQVKIIAT
CCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SGLISKTKLTEIVNTGANSFLAKPYTVNELLLALHEVMT
CCCCCHHHHHHHHHCCCCHHEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADEIIKVLLVEDNPGDAFLIQELIKEVNTANLELYPVERLSEALKILASDTSDGSVPRF
CCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCEE
DVMLLDLSLPDSQGIDTFVRANRETNVLPIIVLTGIDDENLALKAMQKGAQDYLVKGQVT
EEEEEEEECCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHCCCHHEEEECCCH
GDLLVRSIRYAIERQRVEEALRHSEERFRVALKNSPIFVFNQDRDLRYTWIYNPIAGWTV
HHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCEEEEECCCCEEEEEEECCCCCCCH
EEMLGKQDSEIMSEQDAQCLTAIKYHVLTTGIGTRQVVSIGTPLGTKYYDLTVEPLRNES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCC
QDIVGITCACIDISERKLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQ
CCEEEEEEEEEECCHHHHHHHHHHHHHEEEEECCCCEEEEECCCCEEEEECCCCCCCCCC
AHEVIGKNASDLLFREPSLEVETALLNVISQGNWQGELNKVTKTGKEIVVASRWSLVYDE
HHHHHCCCCHHHEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEECEEEEECC
QGKPKSILSVDTDITQKKHLEAQLFRTQRLESIGTLASGIAHDLNNILTPILAGAQLLPL
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
KFPDADERTQHLLEILEINAKRGADLVKQVLSFARGVEGKRITLQLKHLIVEVVKILKET
ECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHH
FPKSIEVYTDIPNDLWMVSGDSTQLHQVLMNLCVNARDAMPDGGTLTISAENLLIDENYA
CCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECEEEEECCCE
RMNLEAKQGPYIMITVSDTGVGISPENLDRIFEPFFTTKAVGQGTGLGLSTVLGIVKSHG
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
GFVNVYSEEGRGTTFRVYLPSVGGTEAPHIDHLLPPAGHGELILIVDDEVSIQDITKTSL
CEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHC
EGHQYETLVASDGVEAIALYAKNADKISAVLMDIMLPVLDGLTTIRTLKKINPQVKIIAT
CCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SGLISKTKLTEIVNTGANSFLAKPYTVNELLLALHEVMT
CCCCCHHHHHHHHHCCCCHHEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA