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The map label for this gene is aroB [H]

Identifier: 17229416

GI number: 17229416

Start: 2305860

End: 2306951

Strand: Direct

Name: aroB [H]

Synonym: alr1924

Alternate gene names: 17229416

Gene position: 2305860-2306951 (Clockwise)

Preceding gene: 17229415

Following gene: 17229417

Centisome position: 35.95

GC content: 43.68

Gene sequence:

>1092_bases
ATGACTTCTGTAATTAATGTGAATCTACCAACGCAGTCTTATGAGATTGCGATCGCACCTGCAAGTTTAGATCAGATTGG
TCAAAGCTTGGCTGGGTTAAAACTGGGCAAGAAAGTATTACTGGTTTCTAATCCCACGATTTTTAAGCATTTCGGCAAAG
TTGCTGTTGATTCCTTAGAAGCTGCTGGATTTCAAGTAGCAAGTTATTCTTTGCCAGCCGGGGAACGCTATAAAACCCTT
AACTCTATTCAAAAACTATACGATATAGCCCTAGAAAATCGCCTAGAACGCTCCTCCACAATGGTGGCTTTGGGGGGAGG
GGTAATTGGTGATATGACTGGCTTTGCCGCCGCTACTTGGCTACGGGGGATTAATGTGGTGCAAGTACCTACCACACTCT
TAGCAATGGTAGATTCGGCTATTGGTGGTAAGACAGGTGTGAATCATCCCCACGGGAAAAACTTGATTGGTGCGTTCCAT
CAGCCGCGATTCGTGTTAATTGATCCCCAAGTATTAAAAACCTTGCCTGTACGTGAATTTCGCGCAGGAATGGCGGAGGT
AATTAAATATGGCGTGATTTGGGATGCAGAATTATTCAACCAGTTGGAACAGAGTAAGCGTCTCGACCAACTGCGCTACA
TCAAACCAGAACTGGTGGATGCTATCTTAACTCGTTCTTGCCAAGCTAAAGCTGATGTTGTCGGCAAAGATGAGAAAGAA
GGTGGACTGAGGGCGATTTTGAATTACGGACACACTGTTGGTCATGCGGTGGAAAGCTTAACTAACTATCGGCTACTCAA
ACATGGTGAAGCAGTAGGTATCGGTATGGTAGCGGCTGGGCAAATCGCTGTAAATTTAGAACTGTGGCAACAAGCAGATG
CAGACCGTCAAAATGCCTTAATTGAAAAAGCGGGTTTACCGACAAAGTTACCAGTGGGATTAGATATTGAAGGGATTATT
GAGGCATTGCAATTAGATAAAAAAGTCAAAGATGGTAAAGTACGGTTTGTTTTACCAACTCAAATTGGTGTAGTGACAGT
TACTGATGAGGTGACATCAGATCACATTCGGCAAGTTTTACAGCAGATGTAA

Upstream 100 bases:

>100_bases
TGTTGGACTTAACTGAAGTTTGGAAATAAAGATATGTCATCCCATCTCCTCCCCAGAATAGGGTAAAATACAGCCCACGG
CGCTTGTTGGGGTTTGGGTA

Downstream 100 bases:

>100_bases
ATTAATTACTAAATTCTGCCAAAATGGCAAATTTTCAGTAGTGGAATCCTATACATTAAATATAGCTACTCAAATAGAGG
TTGTTGATACAATCAACAAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTSVINVNLPTQSYEIAIAPASLDQIGQSLAGLKLGKKVLLVSNPTIFKHFGKVAVDSLEAAGFQVASYSLPAGERYKTL
NSIQKLYDIALENRLERSSTMVALGGGVIGDMTGFAAATWLRGINVVQVPTTLLAMVDSAIGGKTGVNHPHGKNLIGAFH
QPRFVLIDPQVLKTLPVREFRAGMAEVIKYGVIWDAELFNQLEQSKRLDQLRYIKPELVDAILTRSCQAKADVVGKDEKE
GGLRAILNYGHTVGHAVESLTNYRLLKHGEAVGIGMVAAGQIAVNLELWQQADADRQNALIEKAGLPTKLPVGLDIEGII
EALQLDKKVKDGKVRFVLPTQIGVVTVTDEVTSDHIRQVLQQM

Sequences:

>Translated_363_residues
MTSVINVNLPTQSYEIAIAPASLDQIGQSLAGLKLGKKVLLVSNPTIFKHFGKVAVDSLEAAGFQVASYSLPAGERYKTL
NSIQKLYDIALENRLERSSTMVALGGGVIGDMTGFAAATWLRGINVVQVPTTLLAMVDSAIGGKTGVNHPHGKNLIGAFH
QPRFVLIDPQVLKTLPVREFRAGMAEVIKYGVIWDAELFNQLEQSKRLDQLRYIKPELVDAILTRSCQAKADVVGKDEKE
GGLRAILNYGHTVGHAVESLTNYRLLKHGEAVGIGMVAAGQIAVNLELWQQADADRQNALIEKAGLPTKLPVGLDIEGII
EALQLDKKVKDGKVRFVLPTQIGVVTVTDEVTSDHIRQVLQQM
>Mature_362_residues
TSVINVNLPTQSYEIAIAPASLDQIGQSLAGLKLGKKVLLVSNPTIFKHFGKVAVDSLEAAGFQVASYSLPAGERYKTLN
SIQKLYDIALENRLERSSTMVALGGGVIGDMTGFAAATWLRGINVVQVPTTLLAMVDSAIGGKTGVNHPHGKNLIGAFHQ
PRFVLIDPQVLKTLPVREFRAGMAEVIKYGVIWDAELFNQLEQSKRLDQLRYIKPELVDAILTRSCQAKADVVGKDEKEG
GLRAILNYGHTVGHAVESLTNYRLLKHGEAVGIGMVAAGQIAVNLELWQQADADRQNALIEKAGLPTKLPVGLDIEGIIE
ALQLDKKVKDGKVRFVLPTQIGVVTVTDEVTSDHIRQVLQQM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=350, Percent_Identity=44.5714285714286, Blast_Score=267, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6320332, Length=320, Percent_Identity=38.75, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39342; Mature: 39211

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVINVNLPTQSYEIAIAPASLDQIGQSLAGLKLGKKVLLVSNPTIFKHFGKVAVDSLE
CCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
AAGFQVASYSLPAGERYKTLNSIQKLYDIALENRLERSSTMVALGGGVIGDMTGFAAATW
HCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
LRGINVVQVPTTLLAMVDSAIGGKTGVNHPHGKNLIGAFHQPRFVLIDPQVLKTLPVREF
HHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEEEECHHHHHHCCHHHH
RAGMAEVIKYGVIWDAELFNQLEQSKRLDQLRYIKPELVDAILTRSCQAKADVVGKDEKE
HHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCC
GGLRAILNYGHTVGHAVESLTNYRLLKHGEAVGIGMVAAGQIAVNLELWQQADADRQNAL
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEEEHHHHCCCCCHHHHH
IEKAGLPTKLPVGLDIEGIIEALQLDKKVKDGKVRFVLPTQIGVVTVTDEVTSDHIRQVL
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECHHHHHHHHHHH
QQM
HHC
>Mature Secondary Structure 
TSVINVNLPTQSYEIAIAPASLDQIGQSLAGLKLGKKVLLVSNPTIFKHFGKVAVDSLE
CCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
AAGFQVASYSLPAGERYKTLNSIQKLYDIALENRLERSSTMVALGGGVIGDMTGFAAATW
HCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
LRGINVVQVPTTLLAMVDSAIGGKTGVNHPHGKNLIGAFHQPRFVLIDPQVLKTLPVREF
HHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEEEECHHHHHHCCHHHH
RAGMAEVIKYGVIWDAELFNQLEQSKRLDQLRYIKPELVDAILTRSCQAKADVVGKDEKE
HHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCC
GGLRAILNYGHTVGHAVESLTNYRLLKHGEAVGIGMVAAGQIAVNLELWQQADADRQNAL
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEEEHHHHCCCCCHHHHH
IEKAGLPTKLPVGLDIEGIIEALQLDKKVKDGKVRFVLPTQIGVVTVTDEVTSDHIRQVL
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECHHHHHHHHHHH
QQM
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA