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The map label for this gene is prmA [H]

Identifier: 17229383

GI number: 17229383

Start: 2261255

End: 2262175

Strand: Direct

Name: prmA [H]

Synonym: alr1891

Alternate gene names: 17229383

Gene position: 2261255-2262175 (Clockwise)

Preceding gene: 17229382

Following gene: 17229384

Centisome position: 35.26

GC content: 44.52

Gene sequence:

>921_bases
ATGGCAAACACTTGGTGGGAACTACAGATTTCATGTGAATCGGCGCTAGAAGACTCTGTTTCTTGGCGACTGGAAGATTT
TGGTTGTCGTGGTACAGCTAGCGAAAGTAAGGGTGATTCTTGCTTAGTTAAGGGTTATTTGCCGATATTTCAAGCACAGT
TATTAGATTTAGCGGCGCTGGGGCTATGGTTGCAACAAGATGCCCTGTGTATAGGATTATCTTCTCCTACCTTGACTTGG
CAGCTAATTGATGAGGAAGATTGGGCGAGTAGCTGGAAACAATATTGGCATCCCCAGGAAATAGGCGATCGCTTTCTCAT
CAACCCCGCATGGCTACCATCACCGGAAAACTCCGATAGGTTAATCATCCGCCTCGACCCTGGCGTAGCATTTGGTACAG
GAAACCATGCTACTACTCAATTATGTCTAGAATCCCTAGAAATGAGATTGAGTGAGGTTCCCAAATCGTTTATCAGTAAA
GGAGGGAACCAAGAACCTGTCATAATTGCGGATATTGGCTGCGGTTCTGGTATCCTTTCGATTGGGGCAGTTTTATTAGG
CGCACAGAAAGTTTATGCAGTAGATACCGACCCTTTAGCTGTGCAGTCAACCTTCAGCAATCGCGCCCTCAACGAAGTAA
ACCCAGAACGCCTAGTACCAGCAGAAGGTAGCGTAGATATCTTAAAGAAACTGATTGAACGCCCGGTAGATGGTATTGTT
TGCAATATTTTAGCTGATGTCATTATTCAATTAGTCCCAGAAATCAGCGAGATATCTAAACCTAGCACTTGGGCTATTTT
TAGCGGGATTTTAGTTGAACAATCTACCTCTGTTGCTGAGGCTTTAGAAAAACACGGTTGGGTAGTCGCTACTATGTGGA
AACGCAAAGAATGGTGCTGCTTAAATGTCAGGCGTACTTAA

Upstream 100 bases:

>100_bases
CGCGTATACAGTAACACTATAGGAGTCAGTAATCAGGAGTCAGAAGTCAGCAGAAATTATTTCTCCTGACTCCTGAATTC
TGGATTCTCAATTTTCAAAA

Downstream 100 bases:

>100_bases
ATTATCAAAAATTGTGAATTTATTCCCTTAGCCAACAGGAGACAAAATTCGTGAATAGAGTGAGAGTGATGAGGTTCCGT
CAACTATCGCTTTCTCTCAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MANTWWELQISCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAALGLWLQQDALCIGLSSPTLTW
QLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENSDRLIIRLDPGVAFGTGNHATTQLCLESLEMRLSEVPKSFISK
GGNQEPVIIADIGCGSGILSIGAVLLGAQKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVAEALEKHGWVVATMWKRKEWCCLNVRRT

Sequences:

>Translated_306_residues
MANTWWELQISCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAALGLWLQQDALCIGLSSPTLTW
QLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENSDRLIIRLDPGVAFGTGNHATTQLCLESLEMRLSEVPKSFISK
GGNQEPVIIADIGCGSGILSIGAVLLGAQKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVAEALEKHGWVVATMWKRKEWCCLNVRRT
>Mature_305_residues
ANTWWELQISCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAALGLWLQQDALCIGLSSPTLTWQ
LIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENSDRLIIRLDPGVAFGTGNHATTQLCLESLEMRLSEVPKSFISKG
GNQEPVIIADIGCGSGILSIGAVLLGAQKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIVC
NILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVAEALEKHGWVVATMWKRKEWCCLNVRRT

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=226, Percent_Identity=34.5132743362832, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33764; Mature: 33633

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTWWELQISCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAAL
CCCCEEEEEEEHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
GLWLQQDALCIGLSSPTLTWQLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENSDR
HHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCE
LIIRLDPGVAFGTGNHATTQLCLESLEMRLSEVPKSFISKGGNQEPVIIADIGCGSGILS
EEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHH
IGAVLLGAQKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
HHHHHHCCCEEEEECCCCCEEEHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHH
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVAEALEKHGWVVATMWKRKEWCC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCEEE
LNVRRT
EEEECC
>Mature Secondary Structure 
ANTWWELQISCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAAL
CCCEEEEEEEHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
GLWLQQDALCIGLSSPTLTWQLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENSDR
HHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCE
LIIRLDPGVAFGTGNHATTQLCLESLEMRLSEVPKSFISKGGNQEPVIIADIGCGSGILS
EEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHH
IGAVLLGAQKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
HHHHHHCCCEEEEECCCCCEEEHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHH
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVAEALEKHGWVVATMWKRKEWCC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCEEE
LNVRRT
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA