Click here to switch to the map view.

The map label for this gene is livJ [C]

Identifier: 17229326

GI number: 17229326

Start: 2199462

End: 2200787

Strand: Direct

Name: livJ [C]

Synonym: alr1834

Alternate gene names: 17229326

Gene position: 2199462-2200787 (Clockwise)

Preceding gene: 17229325

Following gene: 17229328

Centisome position: 34.29

GC content: 47.59

Gene sequence:

>1326_bases
ATGCAAAGAATTAGTGCTGCCCTCAGTTTAGGTTTAGCTACCTTCACCGCAGGTTTTCTTTTAGCAGCTTGTGAAACAAG
TAATACCACACCTAATGGCGCAGCTAACAATGGCGCAACTAGTACCCCAGCCACAGACACCACTGCGACCAGTGGTGGGT
CAGGGCTAAAAATTGGTTCTCTCCTGCCAGCAACAGGCGATTTAGCATCTATTGGACAACAAATGGCTGCGGCTGTTCCC
TTAGTAGTAGAAACAGTCAACGCTTGCGGCGGTGTGAATGGTCAACCTGTTAGCCTAGTGGCTGTAGACGACCAAACAGA
CCCGAAAGCAGGCGCGGCTGGTATGACTAAACTAGCAACTGTAGATAAGGTTGCGGGTGTAGTCGGCTCTTTTGCTAGCA
GCGTTTCCACAGCTGCCGTCTCCATTGCGGCCCAAAATAAAGTCTTACTAATTTCCCCTGGTAGTACCAGTCCCGTATTT
ACCGAAAAAGCGCAGAAAGGCGACTTTAATGGCTTTTGGGCGCGGACAGTTCCCCCTGATAGCTATCAAGGCCCAGCCTT
AGCCGAACTTGCCAACAAGAAAGGCTTTAAGCGAGTTTCCACCATTGTGATTAACAATGACTATGGAGTGGGTTTTGAAA
AAGCATTTGTCCAAGCTTTTGAAAAACTCGGTGGGACTGTAGTTAACAAAAATAATCCTGTACGCTACGACCCCAAAGCA
ACCACCTTTGAAACCGAAGCGGCGGCGGCCTTTGCTGGTAAGCCAGATGCAGTTCTTGGTGTTTTTTACGTAGAAACAGG
TAGCTTACTACTAAAATCAGCCTATCAGCAAGGTGTGGCTCAAGGTGTACAAATCATGCTGACAGATGGCATGAAATCCG
ATGAGTTTCCGGCGCAAGTCGGTAAAACTGCTGATGGTAAATTTATCGCCTCTGGCATCATTGGCACAGTTCCTGGTTCC
GATGGTAAAGGATTAGAAGCCTTAACAAAGCTTTGGCAATCGAAAAAAGGCAGTGCGCCAGGAGAATTCGCACCCCAAGC
ATGGGACGCGACAGCCTTGTTAGTGTTGGCAGCCCAAGCCGCCAAGGAAAATACTGGTGTGGGTATTGCTGGTAAAATCC
GTGATGTATCTAGTGCGCCTGGTGTAGAAGTTACTGATGTTTGTGAAGGGCTAAAGTTACTCCAGGAGGGCAAAGATATC
AACTATCAAGGAGCTAGTGGTAACGTTGATATTGATGCAAATGGTGATGTCATCGGTGTCTATGATGTGTGGACAGTAGG
CGACGATGGCAAGATTAAGACTATTGACAAAGTGACTCCTAAGTAG

Upstream 100 bases:

>100_bases
TCATTTAACATTTAGAGTCCTGTTAAGATTAAGCTAACTTGAAAATTTAGTTTAAATCTTACTTTTAGGCTCCCGCATCT
TTGAGGAGTGAAAGTAATCT

Downstream 100 bases:

>100_bases
TTGAAAGAGGTGGGGATTGGAGGACATTAATCCCAATCCCCCATCCAAGGTAAAAGTCAAAAGAAAAAATCTTTTACTTT
TTACTTTTTTATCCCCAATC

Product: hypothetical protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MQRISAALSLGLATFTAGFLLAACETSNTTPNGAANNGATSTPATDTTATSGGSGLKIGSLLPATGDLASIGQQMAAAVP
LVVETVNACGGVNGQPVSLVAVDDQTDPKAGAAGMTKLATVDKVAGVVGSFASSVSTAAVSIAAQNKVLLISPGSTSPVF
TEKAQKGDFNGFWARTVPPDSYQGPALAELANKKGFKRVSTIVINNDYGVGFEKAFVQAFEKLGGTVVNKNNPVRYDPKA
TTFETEAAAAFAGKPDAVLGVFYVETGSLLLKSAYQQGVAQGVQIMLTDGMKSDEFPAQVGKTADGKFIASGIIGTVPGS
DGKGLEALTKLWQSKKGSAPGEFAPQAWDATALLVLAAQAAKENTGVGIAGKIRDVSSAPGVEVTDVCEGLKLLQEGKDI
NYQGASGNVDIDANGDVIGVYDVWTVGDDGKIKTIDKVTPK

Sequences:

>Translated_441_residues
MQRISAALSLGLATFTAGFLLAACETSNTTPNGAANNGATSTPATDTTATSGGSGLKIGSLLPATGDLASIGQQMAAAVP
LVVETVNACGGVNGQPVSLVAVDDQTDPKAGAAGMTKLATVDKVAGVVGSFASSVSTAAVSIAAQNKVLLISPGSTSPVF
TEKAQKGDFNGFWARTVPPDSYQGPALAELANKKGFKRVSTIVINNDYGVGFEKAFVQAFEKLGGTVVNKNNPVRYDPKA
TTFETEAAAAFAGKPDAVLGVFYVETGSLLLKSAYQQGVAQGVQIMLTDGMKSDEFPAQVGKTADGKFIASGIIGTVPGS
DGKGLEALTKLWQSKKGSAPGEFAPQAWDATALLVLAAQAAKENTGVGIAGKIRDVSSAPGVEVTDVCEGLKLLQEGKDI
NYQGASGNVDIDANGDVIGVYDVWTVGDDGKIKTIDKVTPK
>Mature_441_residues
MQRISAALSLGLATFTAGFLLAACETSNTTPNGAANNGATSTPATDTTATSGGSGLKIGSLLPATGDLASIGQQMAAAVP
LVVETVNACGGVNGQPVSLVAVDDQTDPKAGAAGMTKLATVDKVAGVVGSFASSVSTAAVSIAAQNKVLLISPGSTSPVF
TEKAQKGDFNGFWARTVPPDSYQGPALAELANKKGFKRVSTIVINNDYGVGFEKAFVQAFEKLGGTVVNKNNPVRYDPKA
TTFETEAAAAFAGKPDAVLGVFYVETGSLLLKSAYQQGVAQGVQIMLTDGMKSDEFPAQVGKTADGKFIASGIIGTVPGS
DGKGLEALTKLWQSKKGSAPGEFAPQAWDATALLVLAAQAAKENTGVGIAGKIRDVSSAPGVEVTDVCEGLKLLQEGKDI
NYQGASGNVDIDANGDVIGVYDVWTVGDDGKIKTIDKVTPK

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Homo sapiens, GI187960069, Length=340, Percent_Identity=23.2352941176471, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI187960067, Length=340, Percent_Identity=23.2352941176471, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4504141, Length=361, Percent_Identity=22.4376731301939, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI48994941, Length=174, Percent_Identity=28.1609195402299, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789867, Length=182, Percent_Identity=26.3736263736264, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 10140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 8822 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal med

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 44801; Mature: 44801

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRISAALSLGLATFTAGFLLAACETSNTTPNGAANNGATSTPATDTTATSGGSGLKIGS
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
LLPATGDLASIGQQMAAAVPLVVETVNACGGVNGQPVSLVAVDDQTDPKAGAAGMTKLAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
VDKVAGVVGSFASSVSTAAVSIAAQNKVLLISPGSTSPVFTEKAQKGDFNGFWARTVPPD
HHHHHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCC
SYQGPALAELANKKGFKRVSTIVINNDYGVGFEKAFVQAFEKLGGTVVNKNNPVRYDPKA
CCCCCHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCEEECCCCCEEECCCC
TTFETEAAAAFAGKPDAVLGVFYVETGSLLLKSAYQQGVAQGVQIMLTDGMKSDEFPAQV
CEECCHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHH
GKTADGKFIASGIIGTVPGSDGKGLEALTKLWQSKKGSAPGEFAPQAWDATALLVLAAQA
CCCCCCCEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
AKENTGVGIAGKIRDVSSAPGVEVTDVCEGLKLLQEGKDINYQGASGNVDIDANGDVIGV
HCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEECCCCCEEEE
YDVWTVGDDGKIKTIDKVTPK
EEEEEECCCCCEEECCCCCCC
>Mature Secondary Structure
MQRISAALSLGLATFTAGFLLAACETSNTTPNGAANNGATSTPATDTTATSGGSGLKIGS
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
LLPATGDLASIGQQMAAAVPLVVETVNACGGVNGQPVSLVAVDDQTDPKAGAAGMTKLAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
VDKVAGVVGSFASSVSTAAVSIAAQNKVLLISPGSTSPVFTEKAQKGDFNGFWARTVPPD
HHHHHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCC
SYQGPALAELANKKGFKRVSTIVINNDYGVGFEKAFVQAFEKLGGTVVNKNNPVRYDPKA
CCCCCHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCEEECCCCCEEECCCC
TTFETEAAAAFAGKPDAVLGVFYVETGSLLLKSAYQQGVAQGVQIMLTDGMKSDEFPAQV
CEECCHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHH
GKTADGKFIASGIIGTVPGSDGKGLEALTKLWQSKKGSAPGEFAPQAWDATALLVLAAQA
CCCCCCCEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
AKENTGVGIAGKIRDVSSAPGVEVTDVCEGLKLLQEGKDINYQGASGNVDIDANGDVIGV
HCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEECCCCCEEEE
YDVWTVGDDGKIKTIDKVTPK
EEEEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA