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The map label for this gene is rbsK [H]

Identifier: 17229276

GI number: 17229276

Start: 2143162

End: 2144085

Strand: Reverse

Name: rbsK [H]

Synonym: all1784

Alternate gene names: 17229276

Gene position: 2144085-2143162 (Counterclockwise)

Preceding gene: 17229279

Following gene: 17229275

Centisome position: 33.43

GC content: 46.43

Gene sequence:

>924_bases
ATGAGCATTATCGTCTTCGGTAGCATCAATATAGATTTAGTTGCCACAGCACCCAAGTTACCAGGTGCAGGAGAAACCTT
ACTGGGAGAAGACTTTTTCAAGGTTCCTGGGGGTAAAGGTGCAAACCAAGCTGTAGCATTAGCAAGATTGGGAGTTCCTA
CCCAGATGGTGGGACGCGTCGGCGCACAGAGTTTTGGTGCAGAACTGATGCAAAATCTGCAAGACGCTGGCGTACAAACT
GACAATATTTTTGTAGATGAAACTGCAAGTTCTGGAGTGGCGATGATCACCGTAGCTCATAACGGTGAAAATCAAATAGT
TGTCATTCCTGGTGCTAATGGGCGAGTCAATCAAGTAGATGTAGAACGATTATCACGCATATTACCAACAGCTACAGCCC
TGCTATTACAATTAGAAATTCCTGTACCTGCCGTTATCGCAGCTGCCCAAGCAGCAAGAAGTAACAATATTACAGTAATT
TTAGACCCCGCACCTGCACCATCAGATTTACCAACAGAACTTTACTCCTTTGTTGATATCATTACCCCCAATGAAGTAGA
AGCTGGGCAACTTGTGGGCTTTCCGGTAGACGGGGAAGATGCAGCGCGAAAGGCAGCAGGGGTGTTATTGCAAAAGGGCG
TGAAAAGTGCGATCGTTAAACTGGGCGCTAAAGGTGTTGTTTGTGCCACAAACAAAGAGACATTTTTTGTCCCAGCCTTC
TCCGTGGATACGCTTGATACTGTAGCGGCTGGTGATGCCTTTAATGGTGGTTTAGCAACAGCACTTTATTCTGGGCTTTC
CTTACATCAGGCAGTTATTTGGGGTGCGGCGGCAGGTGCTTTAGCCGCAACAAAATTAGGCGCACAAACTTCGTTGCCTG
ACAAGTTGACATTTGAGGCCTTCCTCAAGGAAAGGGTTTTGTGA

Upstream 100 bases:

>100_bases
AATCAACTTGATTATTTAGCTTCCTACTTGACAAATCAGTTTAATATCATGTGTGTTGAATGGATTTCTCGTTTTCATCC
GTAAGTCCTAAATCATCATC

Downstream 100 bases:

>100_bases
CTTTTGTGAAGTTTCTTATACTTAAAGTTTCCGAAATTCCTCGGATTGCACTTGAATTTAAAACTATTCAAGATACTCCA
TACAGGAGAGTAGATTCATG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSIIVFGSINIDLVATAPKLPGAGETLLGEDFFKVPGGKGANQAVALARLGVPTQMVGRVGAQSFGAELMQNLQDAGVQT
DNIFVDETASSGVAMITVAHNGENQIVVIPGANGRVNQVDVERLSRILPTATALLLQLEIPVPAVIAAAQAARSNNITVI
LDPAPAPSDLPTELYSFVDIITPNEVEAGQLVGFPVDGEDAARKAAGVLLQKGVKSAIVKLGAKGVVCATNKETFFVPAF
SVDTLDTVAAGDAFNGGLATALYSGLSLHQAVIWGAAAGALAATKLGAQTSLPDKLTFEAFLKERVL

Sequences:

>Translated_307_residues
MSIIVFGSINIDLVATAPKLPGAGETLLGEDFFKVPGGKGANQAVALARLGVPTQMVGRVGAQSFGAELMQNLQDAGVQT
DNIFVDETASSGVAMITVAHNGENQIVVIPGANGRVNQVDVERLSRILPTATALLLQLEIPVPAVIAAAQAARSNNITVI
LDPAPAPSDLPTELYSFVDIITPNEVEAGQLVGFPVDGEDAARKAAGVLLQKGVKSAIVKLGAKGVVCATNKETFFVPAF
SVDTLDTVAAGDAFNGGLATALYSGLSLHQAVIWGAAAGALAATKLGAQTSLPDKLTFEAFLKERVL
>Mature_306_residues
SIIVFGSINIDLVATAPKLPGAGETLLGEDFFKVPGGKGANQAVALARLGVPTQMVGRVGAQSFGAELMQNLQDAGVQTD
NIFVDETASSGVAMITVAHNGENQIVVIPGANGRVNQVDVERLSRILPTATALLLQLEIPVPAVIAAAQAARSNNITVIL
DPAPAPSDLPTELYSFVDIITPNEVEAGQLVGFPVDGEDAARKAAGVLLQKGVKSAIVKLGAKGVVCATNKETFFVPAFS
VDTLDTVAAGDAFNGGLATALYSGLSLHQAVIWGAAAGALAATKLGAQTSLPDKLTFEAFLKERVL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=37.542662116041, Blast_Score=178, Evalue=6e-45,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=42.1052631578947, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI87081971, Length=280, Percent_Identity=25.3571428571429, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082343, Length=292, Percent_Identity=29.4520547945205, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788491, Length=299, Percent_Identity=24.0802675585284, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788417, Length=304, Percent_Identity=26.9736842105263, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=36.6438356164384, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319884, Length=326, Percent_Identity=31.9018404907975, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=35.5481727574751, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24583886, Length=309, Percent_Identity=32.0388349514563, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31507; Mature: 31376

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIVFGSINIDLVATAPKLPGAGETLLGEDFFKVPGGKGANQAVALARLGVPTQMVGRV
CEEEEEECCCEEEEEECCCCCCCCCCHHCCCCEECCCCCCCCHHHHHHHCCCCHHHHHHH
GAQSFGAELMQNLQDAGVQTDNIFVDETASSGVAMITVAHNGENQIVVIPGANGRVNQVD
CHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEC
VERLSRILPTATALLLQLEIPVPAVIAAAQAARSNNITVILDPAPAPSDLPTELYSFVDI
HHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHC
ITPNEVEAGQLVGFPVDGEDAARKAAGVLLQKGVKSAIVKLGAKGVVCATNKETFFVPAF
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEE
SVDTLDTVAAGDAFNGGLATALYSGLSLHQAVIWGAAAGALAATKLGAQTSLPDKLTFEA
CCCCHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLKERVL
HHHHHCC
>Mature Secondary Structure 
SIIVFGSINIDLVATAPKLPGAGETLLGEDFFKVPGGKGANQAVALARLGVPTQMVGRV
EEEEEECCCEEEEEECCCCCCCCCCHHCCCCEECCCCCCCCHHHHHHHCCCCHHHHHHH
GAQSFGAELMQNLQDAGVQTDNIFVDETASSGVAMITVAHNGENQIVVIPGANGRVNQVD
CHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEC
VERLSRILPTATALLLQLEIPVPAVIAAAQAARSNNITVILDPAPAPSDLPTELYSFVDI
HHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHC
ITPNEVEAGQLVGFPVDGEDAARKAAGVLLQKGVKSAIVKLGAKGVVCATNKETFFVPAF
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEE
SVDTLDTVAAGDAFNGGLATALYSGLSLHQAVIWGAAAGALAATKLGAQTSLPDKLTFEA
CCCCHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLKERVL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]