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The map label for this gene is lgrC [H]

Identifier: 17229187

GI number: 17229187

Start: 2024988

End: 2029337

Strand: Reverse

Name: lgrC [H]

Synonym: all1695

Alternate gene names: 17229187

Gene position: 2029337-2024988 (Counterclockwise)

Preceding gene: 17229188

Following gene: 17229186

Centisome position: 31.64

GC content: 38.74

Gene sequence:

>4350_bases
ATGACTATTTCCACTTCATCAAATCAAATTATAGGATTTAAATTATTAGAAGAATGGACAAATACAAAAACAGATTATCC
TAGAAATTCTACAATTCATGAATTATTTAGAATTCAAGTATTAACAACACCTAACTCCGTTGCAGTTGAGTATAAAAATC
AGAAGATTACCTATCAAGAACTTGAAAATAAATCAAATCAATTTGCCTATTATTTGCGGCATATTGGAGTAAAAAAAGAA
ACTTTAGTCGCTTTATATTTAGAACGTTCTCCTGATGTAATTATTGCTATATTAGCTATTTTAAAAGCAGGGGGAGCTTA
TTTGCCATTAGATATTTCCGCTCCTTTAGAACGATTGGAAACTATCATAAAGGATGCCGAAGCGTTCATTTTAATTACTC
AAGAATCTCAATTAAATTATCTGGAAAAAATTACAGATGAGATTCAAACTATCTGTATTGATAACCAAAGTAATTTAACG
GATTTTTCTGATGATATTTCTCTGTGTAGTGAAGTCACTGCCCACAATTTAGCCTATGTTATGTACACATCAGGCTCAAC
AGGTAAACCCAAGGGTGTTTGCGTAGAACATCGTGGTGTTGTACGACTAGTGAAAAATACGAACTATGCTAATTTTAGTT
GTGATGAGGTTATCTTACAACTTGCTTCTATAGCCTTTGATGCAGCAACATTTGAGATTTGGGCTGCTTTATTAAATGGC
GGAAAATTGGTATTGATGCCAATCAACATACCTTCTTTGCAAGAAATTGGTATGGCGATTAAACAATACCATGTTACTAC
TTTATGGTTAACAGCCGGATTATTTAATTTAATGGTAGAGGAGCAAATAGAACATCTAAAATCCTTGCGACAACTTTTAG
CAGGGGGTGATGTTTTATCAGTGTATCATGTCAGTAAAGTCATAGAAGAATTACCAAATTGTCAATTAATCAATGGTTAT
GGCCCCACGGAAAATACAACCTTTACCTGTTGCCATAAAATTACTGTTAATGACCTGATAAAAGATTCAATTCCTATTGG
TCGTCCCATTGCGAATACCCAAGTATATATACTCGATGATGTTTTACAATTAGTTCCTATTGGGATTGCCGGTGAACTCT
ATATTGGAGGTGATGGGTTAGCACGGGGTTATTTAAATAAACCGGACTTAACAGCAGAAAAATTTATTCCCCATCCTTTT
AGTGATAAACCCAACAGTCGTCTCTATAAAACAGGCGATCGCGTTCGCTGGCTACCCGATGGTACAATAGAGTTTTTGGG
ACGAATTGATTTTCAAGTAAAAATCAGAGGCTTCCGGGTAGAATTGGGTGAAATTGAGGCAATATTAGCACAGCATCCAT
CAGTGCGATCGGCGGTTGTACTAGCACAGGAATACCAGCCAGCAGACAAGCGATTAGTAGCATACTTTACTAGGGAAGAA
AATTGCAACACAGTAGCCCCTAGTGAATTACGCCATTTTCTCCAACAGAAATTGCCAAATTATATGATTCCATCGGCTTT
TATCTCGTTGGAGAAGTTACCTCTTAATGCTAACGGTAAGGTAGATCGAAAAGCTCTACCGAATGTAGATAAAATCTGCA
TAGATACAGATAGCAATTTTGTTTCCCCCCGTACCCCGACTGAGGCAAGGCTAGCTAGTATTTGGGCAGATGTTTTGGGT
ACACAAGTAGGAATCTATCAACCATTTTTAGAAGTAGGTGGACACTCCCTTCATTCCACTCAGATTGTTTCCCGCGTGCG
GGACTGTTTTGGAATCAATTTGCCTGTTTACGCAGTTCTAGAGGCATCGACAATTGCTGAGTTGAGTCGATGGATTGAAT
CGCCAGATCAGCAACAACAGCCTAAACAGAGTGTTCCAGCATTGCAACCCATTTCGCATCAAAATAACCTACCTCTGTCG
TTATATCAGGAACGATTGTGGGTGTCAGAACAAAAATCTGGTTTCAAACCGATTTACAACCTACCAATGGCCTTTCGGCT
AAAAGGAATTCTGCACATTTCGAGTTTGGAACAGGCCATCAACACAATTATTCAACGACACGAATCTCTGCGAACTACAT
TTCCCATTCTGGAAGGACTACCTGTTCAACACATTGCTTCAGAATTAATTATTGCCATTCCCATTCAGCAGGTTGAGAAC
GATGGGAAAATGGAGATACAACAGTTAGTCAATGCAGAAGCCAGACAACCATTTGACCTGACACAAGAGCCACCAATTCG
CGCTCGGTTACTGCGGTTAACAGAGAAAGATCATGTACTGATGATCACGATACATCACATTGTTGCCGATGGTTGGTCAT
TAGGAATCTTTAACCAGGAGCTATCAGATATCTACGCAGCTTATACCCAACAATCTCCTTGTCCCCTAGCTCCACCATTA
TTTCAGTACAGAGATTTTAGCCTTTGGCATCAGCAACAGTTTCAGCAGCCAGAGGTATATACCCCTTTAGTAGAGTACTG
GAGTCATCAACTAGCCGATGCCCCTCCTTTACTGCAATTACCAAGCGATCGCCCTCGCCCTCCATTACAATCTTTTCAAG
GACGTATCCAATCATTTCAAATTGACTCAGAGCTAACGCAGCAACTAAAAAACCTCAGCCAACAGTCTGGATCTACGCTA
TTCATAACACTGTTAGCAAGTTTCGTGATTTTACTGCATTCCTACAGTAGTCAAAAGGACATGGTAATAGGTTCCGCAGT
TGCAAACCGCAACCACACCGAAATTGAATCTGTCATTGGCTGTTTCTCTAACATTATGCCGCTTCGCATCAGTCTAGCGG
GGAATCCGTCTTTTCTCAATTTACTCCAGCACTTACGCCAAACTACTCTAGAAGCCTATATCCATCAAGACTTTCCTGTT
GAGCAACTGCTACCTACTCTACAATCAACCAGAGATTTAAGCTACTCTCCCTGGTATCAGGTGATATTTAATCTGCTGAA
TGTACCTATGAGTAATCTAGAGCTAACTGGACTGAACATAGAGTCACTACCAATTGAGAAAAATACTGCTCTATTTGATT
TGTCTCTGTTAATGTGGGAAACAACCGCAGGCTTATCAGGAATCTTTGAATACAATAGTGATCTGTTCAATGAACGCACA
ATTGAACAGTTAATCCAAGACTTTCAGGTCTTATTACAAAAACTTTTAGCCAATCCAAATCAGAGTATTCGATCACTACC
GATGTTGATGAAGGACGAACAATATTGGCAGCAACAGAAAAATCAACTAACTCACCATATCTCATCAAATATCAATCCAC
CTGGACAAGTCACGAACGCGACAGATTTTTTTCCTCAAGATGATTTAGAGCAGCAACTAATCACAATCTGGGAAAAAGTT
TTGGGTGTTTCATCTATAGGTGTTAACGATAATTTCTTTAATTTGGGAGGACATTCTTTATTAGCATTACGCCTATTTGC
CCAAATTGAGAAAACTTTGGGCAAAAAACTGCCCCTAGCAACTCTTTTTAAAGTACCAACAATTAAAGAACTTGCTCAGG
TAATTCGGCACACAGAGAATTTAGAATCTTCATTTACTCTAAATTCCTCCCAATTTGATCCAGAAGATTATCGCAAACTT
ATGGCCATTAATGCTGGCCGTCAGGGAGAAAAACCTAGACCTGAGTCCTTAATCGTCAGTTTTAATCATCAAGGTAATAA
ACAGCCATTTTTCTTGTGTGCTAATGCTTTAGATGAAGTGTTGCCACTCGCACCATACCTTGGGCAGGAACAACCAATTT
ACTTTATGGAATCAGGTTTATCTGTCTTTAAACATAGAGCTACAGAAGAAAATATCCAAGCACTTGCGGCTTATCATCTG
AATGACATTCTCACCTTGCAACCAAAAGGAGATTATATTTTGGGTGGTTTTTCTTTTGGTTGTTTAGTGGCTTATGAAAT
TGCCAAACAACTTGAGCGTCTTGGTAAAAAGGTTGCTATCCTCACAATAGTAGATTTTCCTGGTTCTGATCCGATTTTCC
ATTACTATTTAGCTAACATATTTCCCATCTTCCCCAAGATAAGACTGTTTTTACAACAGCCTCACAAAAGTCTCGCTAAA
AAGAATAAAAACAACTCCTCTTCCAGAAAGAAGAACTTGCAGCCTCGTATTACACCAGGCTACTCTGGCAAGATTCACCT
TTTTTTAGCTAGCGATTTGTCTTTATCTTACAAGTTATTACGTTTTCTTTTTCCTCTTTTTGGTTGGAATAAGCAAATAG
TAGAGAGGGTTTACCAACTGCCGGGTAATCACAGAAGTTTGCTCGAAGAACCTCATGTGAAGGTGTTAGCAGATAGATTC
ACTCTTTTGTTTAGAGATATCAATTTTTAG

Upstream 100 bases:

>100_bases
CAGAAAAATTATGAGCTTGTCAATTAAGATACGTACTTATATAAGCTCTATAATAATTTTGAAATAGCACCCAATTTAAA
AGTTAATCTGTGTTAAGAAG

Downstream 100 bases:

>100_bases
CTTGATGTAGAGCGACAAATAATTTGTCGAAGTGGTCAAATAATTTGTCGCTCTACAACAAAAATCGGGATGACTGGATT
CGAACCAGCGGCCCCTTCGT

Product: hypothetical protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1449; Mature: 1448

Protein sequence:

>1449_residues
MTISTSSNQIIGFKLLEEWTNTKTDYPRNSTIHELFRIQVLTTPNSVAVEYKNQKITYQELENKSNQFAYYLRHIGVKKE
TLVALYLERSPDVIIAILAILKAGGAYLPLDISAPLERLETIIKDAEAFILITQESQLNYLEKITDEIQTICIDNQSNLT
DFSDDISLCSEVTAHNLAYVMYTSGSTGKPKGVCVEHRGVVRLVKNTNYANFSCDEVILQLASIAFDAATFEIWAALLNG
GKLVLMPINIPSLQEIGMAIKQYHVTTLWLTAGLFNLMVEEQIEHLKSLRQLLAGGDVLSVYHVSKVIEELPNCQLINGY
GPTENTTFTCCHKITVNDLIKDSIPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPF
SDKPNSRLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVLAQEYQPADKRLVAYFTREE
NCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKVDRKALPNVDKICIDTDSNFVSPRTPTEARLASIWADVLG
TQVGIYQPFLEVGGHSLHSTQIVSRVRDCFGINLPVYAVLEASTIAELSRWIESPDQQQQPKQSVPALQPISHQNNLPLS
LYQERLWVSEQKSGFKPIYNLPMAFRLKGILHISSLEQAINTIIQRHESLRTTFPILEGLPVQHIASELIIAIPIQQVEN
DGKMEIQQLVNAEARQPFDLTQEPPIRARLLRLTEKDHVLMITIHHIVADGWSLGIFNQELSDIYAAYTQQSPCPLAPPL
FQYRDFSLWHQQQFQQPEVYTPLVEYWSHQLADAPPLLQLPSDRPRPPLQSFQGRIQSFQIDSELTQQLKNLSQQSGSTL
FITLLASFVILLHSYSSQKDMVIGSAVANRNHTEIESVIGCFSNIMPLRISLAGNPSFLNLLQHLRQTTLEAYIHQDFPV
EQLLPTLQSTRDLSYSPWYQVIFNLLNVPMSNLELTGLNIESLPIEKNTALFDLSLLMWETTAGLSGIFEYNSDLFNERT
IEQLIQDFQVLLQKLLANPNQSIRSLPMLMKDEQYWQQQKNQLTHHISSNINPPGQVTNATDFFPQDDLEQQLITIWEKV
LGVSSIGVNDNFFNLGGHSLLALRLFAQIEKTLGKKLPLATLFKVPTIKELAQVIRHTENLESSFTLNSSQFDPEDYRKL
MAINAGRQGEKPRPESLIVSFNHQGNKQPFFLCANALDEVLPLAPYLGQEQPIYFMESGLSVFKHRATEENIQALAAYHL
NDILTLQPKGDYILGGFSFGCLVAYEIAKQLERLGKKVAILTIVDFPGSDPIFHYYLANIFPIFPKIRLFLQQPHKSLAK
KNKNNSSSRKKNLQPRITPGYSGKIHLFLASDLSLSYKLLRFLFPLFGWNKQIVERVYQLPGNHRSLLEEPHVKVLADRF
TLLFRDINF

Sequences:

>Translated_1449_residues
MTISTSSNQIIGFKLLEEWTNTKTDYPRNSTIHELFRIQVLTTPNSVAVEYKNQKITYQELENKSNQFAYYLRHIGVKKE
TLVALYLERSPDVIIAILAILKAGGAYLPLDISAPLERLETIIKDAEAFILITQESQLNYLEKITDEIQTICIDNQSNLT
DFSDDISLCSEVTAHNLAYVMYTSGSTGKPKGVCVEHRGVVRLVKNTNYANFSCDEVILQLASIAFDAATFEIWAALLNG
GKLVLMPINIPSLQEIGMAIKQYHVTTLWLTAGLFNLMVEEQIEHLKSLRQLLAGGDVLSVYHVSKVIEELPNCQLINGY
GPTENTTFTCCHKITVNDLIKDSIPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPF
SDKPNSRLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVLAQEYQPADKRLVAYFTREE
NCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKVDRKALPNVDKICIDTDSNFVSPRTPTEARLASIWADVLG
TQVGIYQPFLEVGGHSLHSTQIVSRVRDCFGINLPVYAVLEASTIAELSRWIESPDQQQQPKQSVPALQPISHQNNLPLS
LYQERLWVSEQKSGFKPIYNLPMAFRLKGILHISSLEQAINTIIQRHESLRTTFPILEGLPVQHIASELIIAIPIQQVEN
DGKMEIQQLVNAEARQPFDLTQEPPIRARLLRLTEKDHVLMITIHHIVADGWSLGIFNQELSDIYAAYTQQSPCPLAPPL
FQYRDFSLWHQQQFQQPEVYTPLVEYWSHQLADAPPLLQLPSDRPRPPLQSFQGRIQSFQIDSELTQQLKNLSQQSGSTL
FITLLASFVILLHSYSSQKDMVIGSAVANRNHTEIESVIGCFSNIMPLRISLAGNPSFLNLLQHLRQTTLEAYIHQDFPV
EQLLPTLQSTRDLSYSPWYQVIFNLLNVPMSNLELTGLNIESLPIEKNTALFDLSLLMWETTAGLSGIFEYNSDLFNERT
IEQLIQDFQVLLQKLLANPNQSIRSLPMLMKDEQYWQQQKNQLTHHISSNINPPGQVTNATDFFPQDDLEQQLITIWEKV
LGVSSIGVNDNFFNLGGHSLLALRLFAQIEKTLGKKLPLATLFKVPTIKELAQVIRHTENLESSFTLNSSQFDPEDYRKL
MAINAGRQGEKPRPESLIVSFNHQGNKQPFFLCANALDEVLPLAPYLGQEQPIYFMESGLSVFKHRATEENIQALAAYHL
NDILTLQPKGDYILGGFSFGCLVAYEIAKQLERLGKKVAILTIVDFPGSDPIFHYYLANIFPIFPKIRLFLQQPHKSLAK
KNKNNSSSRKKNLQPRITPGYSGKIHLFLASDLSLSYKLLRFLFPLFGWNKQIVERVYQLPGNHRSLLEEPHVKVLADRF
TLLFRDINF
>Mature_1448_residues
TISTSSNQIIGFKLLEEWTNTKTDYPRNSTIHELFRIQVLTTPNSVAVEYKNQKITYQELENKSNQFAYYLRHIGVKKET
LVALYLERSPDVIIAILAILKAGGAYLPLDISAPLERLETIIKDAEAFILITQESQLNYLEKITDEIQTICIDNQSNLTD
FSDDISLCSEVTAHNLAYVMYTSGSTGKPKGVCVEHRGVVRLVKNTNYANFSCDEVILQLASIAFDAATFEIWAALLNGG
KLVLMPINIPSLQEIGMAIKQYHVTTLWLTAGLFNLMVEEQIEHLKSLRQLLAGGDVLSVYHVSKVIEELPNCQLINGYG
PTENTTFTCCHKITVNDLIKDSIPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPFS
DKPNSRLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVLAQEYQPADKRLVAYFTREEN
CNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKVDRKALPNVDKICIDTDSNFVSPRTPTEARLASIWADVLGT
QVGIYQPFLEVGGHSLHSTQIVSRVRDCFGINLPVYAVLEASTIAELSRWIESPDQQQQPKQSVPALQPISHQNNLPLSL
YQERLWVSEQKSGFKPIYNLPMAFRLKGILHISSLEQAINTIIQRHESLRTTFPILEGLPVQHIASELIIAIPIQQVEND
GKMEIQQLVNAEARQPFDLTQEPPIRARLLRLTEKDHVLMITIHHIVADGWSLGIFNQELSDIYAAYTQQSPCPLAPPLF
QYRDFSLWHQQQFQQPEVYTPLVEYWSHQLADAPPLLQLPSDRPRPPLQSFQGRIQSFQIDSELTQQLKNLSQQSGSTLF
ITLLASFVILLHSYSSQKDMVIGSAVANRNHTEIESVIGCFSNIMPLRISLAGNPSFLNLLQHLRQTTLEAYIHQDFPVE
QLLPTLQSTRDLSYSPWYQVIFNLLNVPMSNLELTGLNIESLPIEKNTALFDLSLLMWETTAGLSGIFEYNSDLFNERTI
EQLIQDFQVLLQKLLANPNQSIRSLPMLMKDEQYWQQQKNQLTHHISSNINPPGQVTNATDFFPQDDLEQQLITIWEKVL
GVSSIGVNDNFFNLGGHSLLALRLFAQIEKTLGKKLPLATLFKVPTIKELAQVIRHTENLESSFTLNSSQFDPEDYRKLM
AINAGRQGEKPRPESLIVSFNHQGNKQPFFLCANALDEVLPLAPYLGQEQPIYFMESGLSVFKHRATEENIQALAAYHLN
DILTLQPKGDYILGGFSFGCLVAYEIAKQLERLGKKVAILTIVDFPGSDPIFHYYLANIFPIFPKIRLFLQQPHKSLAKK
NKNNSSSRKKNLQPRITPGYSGKIHLFLASDLSLSYKLLRFLFPLFGWNKQIVERVYQLPGNHRSLLEEPHVKVLADRFT
LLFRDINF

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=673, Percent_Identity=23.6255572065379, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI38505220, Length=504, Percent_Identity=23.4126984126984, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI187761345, Length=542, Percent_Identity=22.140221402214, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI187761343, Length=542, Percent_Identity=22.140221402214, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI122937307, Length=505, Percent_Identity=21.980198019802, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI42544132, Length=506, Percent_Identity=20.3557312252964, Blast_Score=79, Evalue=3e-14,
Organism=Escherichia coli, GI1786801, Length=629, Percent_Identity=32.4324324324324, Blast_Score=281, Evalue=3e-76,
Organism=Escherichia coli, GI145693145, Length=524, Percent_Identity=23.6641221374046, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788107, Length=569, Percent_Identity=23.9015817223199, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI1786810, Length=512, Percent_Identity=25.390625, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI221142682, Length=509, Percent_Identity=24.3614931237721, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17556356, Length=556, Percent_Identity=26.0791366906475, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17550940, Length=621, Percent_Identity=25.2818035426731, Blast_Score=150, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17538037, Length=552, Percent_Identity=22.6449275362319, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17557194, Length=539, Percent_Identity=22.2634508348794, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560140, Length=545, Percent_Identity=21.8348623853211, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32564420, Length=487, Percent_Identity=22.3819301848049, Blast_Score=88, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32564422, Length=487, Percent_Identity=22.3819301848049, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994703, Length=579, Percent_Identity=21.0708117443869, Blast_Score=83, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71994694, Length=579, Percent_Identity=21.0708117443869, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994690, Length=580, Percent_Identity=21.0344827586207, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=513, Percent_Identity=23.0019493177388, Blast_Score=77, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560308, Length=364, Percent_Identity=24.4505494505494, Blast_Score=73, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=699, Percent_Identity=26.6094420600858, Blast_Score=227, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6319699, Length=364, Percent_Identity=23.9010989010989, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648676, Length=669, Percent_Identity=29.1479820627803, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI18859661, Length=521, Percent_Identity=21.6890595009597, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355181, Length=496, Percent_Identity=21.3709677419355, Blast_Score=79, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581924, Length=521, Percent_Identity=20.3454894433781, Blast_Score=78, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19922652, Length=510, Percent_Identity=21.9607843137255, Blast_Score=77, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582852, Length=523, Percent_Identity=23.9005736137667, Blast_Score=71, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 163986; Mature: 163854

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISTSSNQIIGFKLLEEWTNTKTDYPRNSTIHELFRIQVLTTPNSVAVEYKNQKITYQE
CEECCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCEEEEECCCEEEHHH
LENKSNQFAYYLRHIGVKKETLVALYLERSPDVIIAILAILKAGGAYLPLDISAPLERLE
HHCCCHHHHHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCEEEEECHHHHHHHH
TIIKDAEAFILITQESQLNYLEKITDEIQTICIDNQSNLTDFSDDISLCSEVTAHNLAYV
HHHCCCCEEEEEECCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCEEEE
MYTSGSTGKPKGVCVEHRGVVRLVKNTNYANFSCDEVILQLASIAFDAATFEIWAALLNG
EEECCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKLVLMPINIPSLQEIGMAIKQYHVTTLWLTAGLFNLMVEEQIEHLKSLRQLLAGGDVLS
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VYHVSKVIEELPNCQLINGYGPTENTTFTCCHKITVNDLIKDSIPIGRPIANTQVYILDD
HHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECHHHHHHHHCCCCCCCCCCCEEEEHHH
VLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPFSDKPNSRLYKTGDRVRWLPD
HHHHHCCCCCCEEEECCCCHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEECCCCEEECCC
GTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVLAQEYQPADKRLVAYFTREE
CHHHHHHCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHEEEHHHCCCCCCEEEEEEECCC
NCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKVDRKALPNVDKICIDTDSNF
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEECCCCC
VSPRTPTEARLASIWADVLGTQVGIYQPFLEVGGHSLHSTQIVSRVRDCFGINLPVYAVL
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHH
EASTIAELSRWIESPDQQQQPKQSVPALQPISHQNNLPLSLYQERLWVSEQKSGFKPIYN
HHHHHHHHHHHHCCCCHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHC
LPMAFRLKGILHISSLEQAINTIIQRHESLRTTFPILEGLPVQHIASELIIAIPIQQVEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEHHHHCC
DGKMEIQQLVNAEARQPFDLTQEPPIRARLLRLTEKDHVLMITIHHIVADGWSLGIFNQE
CCHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHCCCEEECHHHH
LSDIYAAYTQQSPCPLAPPLFQYRDFSLWHQQQFQQPEVYTPLVEYWSHQLADAPPLLQL
HHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PSDRPRPPLQSFQGRIQSFQIDSELTQQLKNLSQQSGSTLFITLLASFVILLHSYSSQKD
CCCCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCC
MVIGSAVANRNHTEIESVIGCFSNIMPLRISLAGNPSFLNLLQHLRQTTLEAYIHQDFPV
EEEEHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCH
EQLLPTLQSTRDLSYSPWYQVIFNLLNVPMSNLELTGLNIESLPIEKNTALFDLSLLMWE
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHH
TTAGLSGIFEYNSDLFNERTIEQLIQDFQVLLQKLLANPNQSIRSLPMLMKDEQYWQQQK
HHCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
NQLTHHISSNINPPGQVTNATDFFPQDDLEQQLITIWEKVLGVSSIGVNDNFFNLGGHSL
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHH
LALRLFAQIEKTLGKKLPLATLFKVPTIKELAQVIRHTENLESSFTLNSSQFDPEDYRKL
HHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
MAINAGRQGEKPRPESLIVSFNHQGNKQPFFLCANALDEVLPLAPYLGQEQPIYFMESGL
HHHCCCCCCCCCCCCEEEEEECCCCCCCHHEEEHHHHHHHHCCCHHCCCCCCCHHHHHHH
SVFKHRATEENIQALAAYHLNDILTLQPKGDYILGGFSFGCLVAYEIAKQLERLGKKVAI
HHHHHHCCHHHHHHHHHHHHCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCEEEE
LTIVDFPGSDPIFHYYLANIFPIFPKIRLFLQQPHKSLAKKNKNNSSSRKKNLQPRITPG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
YSGKIHLFLASDLSLSYKLLRFLFPLFGWNKQIVERVYQLPGNHRSLLEEPHVKVLADRF
CCCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCHHHHHHHH
TLLFRDINF
HHHHHHCCC
>Mature Secondary Structure 
TISTSSNQIIGFKLLEEWTNTKTDYPRNSTIHELFRIQVLTTPNSVAVEYKNQKITYQE
EECCCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCEEEEECCCEEEHHH
LENKSNQFAYYLRHIGVKKETLVALYLERSPDVIIAILAILKAGGAYLPLDISAPLERLE
HHCCCHHHHHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCEEEEECHHHHHHHH
TIIKDAEAFILITQESQLNYLEKITDEIQTICIDNQSNLTDFSDDISLCSEVTAHNLAYV
HHHCCCCEEEEEECCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCEEEE
MYTSGSTGKPKGVCVEHRGVVRLVKNTNYANFSCDEVILQLASIAFDAATFEIWAALLNG
EEECCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKLVLMPINIPSLQEIGMAIKQYHVTTLWLTAGLFNLMVEEQIEHLKSLRQLLAGGDVLS
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VYHVSKVIEELPNCQLINGYGPTENTTFTCCHKITVNDLIKDSIPIGRPIANTQVYILDD
HHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECHHHHHHHHCCCCCCCCCCCEEEEHHH
VLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPFSDKPNSRLYKTGDRVRWLPD
HHHHHCCCCCCEEEECCCCHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEECCCCEEECCC
GTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVLAQEYQPADKRLVAYFTREE
CHHHHHHCCCEEEEEEEEEEEHHHHHHHHHCCCCHHHHEEEHHHCCCCCCEEEEEEECCC
NCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKVDRKALPNVDKICIDTDSNF
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEECCCCC
VSPRTPTEARLASIWADVLGTQVGIYQPFLEVGGHSLHSTQIVSRVRDCFGINLPVYAVL
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHH
EASTIAELSRWIESPDQQQQPKQSVPALQPISHQNNLPLSLYQERLWVSEQKSGFKPIYN
HHHHHHHHHHHHCCCCHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHC
LPMAFRLKGILHISSLEQAINTIIQRHESLRTTFPILEGLPVQHIASELIIAIPIQQVEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEHHHHCC
DGKMEIQQLVNAEARQPFDLTQEPPIRARLLRLTEKDHVLMITIHHIVADGWSLGIFNQE
CCHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHCCCEEECHHHH
LSDIYAAYTQQSPCPLAPPLFQYRDFSLWHQQQFQQPEVYTPLVEYWSHQLADAPPLLQL
HHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PSDRPRPPLQSFQGRIQSFQIDSELTQQLKNLSQQSGSTLFITLLASFVILLHSYSSQKD
CCCCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCC
MVIGSAVANRNHTEIESVIGCFSNIMPLRISLAGNPSFLNLLQHLRQTTLEAYIHQDFPV
EEEEHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCH
EQLLPTLQSTRDLSYSPWYQVIFNLLNVPMSNLELTGLNIESLPIEKNTALFDLSLLMWE
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHH
TTAGLSGIFEYNSDLFNERTIEQLIQDFQVLLQKLLANPNQSIRSLPMLMKDEQYWQQQK
HHCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
NQLTHHISSNINPPGQVTNATDFFPQDDLEQQLITIWEKVLGVSSIGVNDNFFNLGGHSL
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHH
LALRLFAQIEKTLGKKLPLATLFKVPTIKELAQVIRHTENLESSFTLNSSQFDPEDYRKL
HHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
MAINAGRQGEKPRPESLIVSFNHQGNKQPFFLCANALDEVLPLAPYLGQEQPIYFMESGL
HHHCCCCCCCCCCCCEEEEEECCCCCCCHHEEEHHHHHHHHCCCHHCCCCCCCHHHHHHH
SVFKHRATEENIQALAAYHLNDILTLQPKGDYILGGFSFGCLVAYEIAKQLERLGKKVAI
HHHHHHCCHHHHHHHHHHHHCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCEEEE
LTIVDFPGSDPIFHYYLANIFPIFPKIRLFLQQPHKSLAKKNKNNSSSRKKNLQPRITPG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
YSGKIHLFLASDLSLSYKLLRFLFPLFGWNKQIVERVYQLPGNHRSLLEEPHVKVLADRF
CCCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCHHHHHHHH
TLLFRDINF
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA