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The map label for this gene is gpsA [H]

Identifier: 17229185

GI number: 17229185

Start: 2022849

End: 2023772

Strand: Reverse

Name: gpsA [H]

Synonym: all1693

Alternate gene names: 17229185

Gene position: 2023772-2022849 (Counterclockwise)

Preceding gene: 17229186

Following gene: 17229184

Centisome position: 31.55

GC content: 45.78

Gene sequence:

>924_bases
GTGCAAGAAACTACTATATCGATTTTGGGTGCAGGTGCTTGGGGTGCATCTCTAGCAAATCTAGCAATAGCCAATGGTAA
CAGGGTGCGTGTATGGTCACGACGAGGATCTGAAACATTGTCAGCAGTTTTGCAGGGTGCGGATATAGTTCTATCTGCCA
TTTCCATGAAAGGAGTGAGAGAAGTTGCTTCACAAATTCAATCTCTCACTCCTTCACCAGAAACTATTTTTGTCACGGCT
ACCAAAGGTCTAGAACCAGAAACGATTTATACCCCGTCGCAAATTTGGCAATCGTGTTTCCCCCATCATCCAGTAGTTGT
CCTATCTGGGCCAAATTTATCTAAAGAAATCGACCAATCCCTACCAGCCGCCACGGTAGTAGCTAGTCGTGTAGCTACCG
CCGCCGCTACAGTGCAGCTGGCATTTTCTTCGTCTCGTTTCCGCGTCTATACAAATCCTGACCCCGTAGGTGTGGAGTTG
GGGGGTACACTCAAGAATGTAATTGCGATCGCCTCTGGTGTATGTGACGGTCTACATTTAGGAACTAATGCCAAAGCCGC
TTTAGTCACGCGCGGACTCACAGAAATGGTTCGCATTGGCAATTGTTGGGGTGCAAAGACGGAAACATTTTATGGTTTAT
CTGGTCTAGGGGATTTGTTAGCTACCTGTAACAGTCCTTTAAGTCGCAATTACCAAGTTGGCTATCAATTAGCCGGTGGT
GAAACACTGGCACAAATTCTAGCAAAATTACCAGGAACCGCCGAAGGAGTAAACACTTGTCAGGTATTAGTCCAACTAGC
TAGGCAACAAAATATAGTTATCCCTATTACCGAGCAAGTTTACCGATTACTACAAGGCGAAGTTACACCACAGCAAGCCC
TTGATGAACTCATGCTCCGAGATATTAAGCCGGAATACAACTAA

Upstream 100 bases:

>100_bases
CGCCGAACAAGTACGACAATTAATGGAGCGTTACCCACGGAACAAGTAGAAGCGTAATCAATCGTGTCTCTACAATTTTG
AATTGAGAATTTTTAAATCG

Downstream 100 bases:

>100_bases
TTGGCGATTGGTGATTGGTAAGGGGTAATTGGTAATTGGTTAATAGTCAACTGACAACAAGTCCCCAATTTAACTCATCA
CTACTCATCATCCCCATTAC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MQETTISILGAGAWGASLANLAIANGNRVRVWSRRGSETLSAVLQGADIVLSAISMKGVREVASQIQSLTPSPETIFVTA
TKGLEPETIYTPSQIWQSCFPHHPVVVLSGPNLSKEIDQSLPAATVVASRVATAAATVQLAFSSSRFRVYTNPDPVGVEL
GGTLKNVIAIASGVCDGLHLGTNAKAALVTRGLTEMVRIGNCWGAKTETFYGLSGLGDLLATCNSPLSRNYQVGYQLAGG
ETLAQILAKLPGTAEGVNTCQVLVQLARQQNIVIPITEQVYRLLQGEVTPQQALDELMLRDIKPEYN

Sequences:

>Translated_307_residues
MQETTISILGAGAWGASLANLAIANGNRVRVWSRRGSETLSAVLQGADIVLSAISMKGVREVASQIQSLTPSPETIFVTA
TKGLEPETIYTPSQIWQSCFPHHPVVVLSGPNLSKEIDQSLPAATVVASRVATAAATVQLAFSSSRFRVYTNPDPVGVEL
GGTLKNVIAIASGVCDGLHLGTNAKAALVTRGLTEMVRIGNCWGAKTETFYGLSGLGDLLATCNSPLSRNYQVGYQLAGG
ETLAQILAKLPGTAEGVNTCQVLVQLARQQNIVIPITEQVYRLLQGEVTPQQALDELMLRDIKPEYN
>Mature_307_residues
MQETTISILGAGAWGASLANLAIANGNRVRVWSRRGSETLSAVLQGADIVLSAISMKGVREVASQIQSLTPSPETIFVTA
TKGLEPETIYTPSQIWQSCFPHHPVVVLSGPNLSKEIDQSLPAATVVASRVATAAATVQLAFSSSRFRVYTNPDPVGVEL
GGTLKNVIAIASGVCDGLHLGTNAKAALVTRGLTEMVRIGNCWGAKTETFYGLSGLGDLLATCNSPLSRNYQVGYQLAGG
ETLAQILAKLPGTAEGVNTCQVLVQLARQQNIVIPITEQVYRLLQGEVTPQQALDELMLRDIKPEYN

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=255, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI33695088, Length=332, Percent_Identity=22.8915662650602, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790037, Length=333, Percent_Identity=33.6336336336336, Blast_Score=171, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI32564403, Length=213, Percent_Identity=30.5164319248826, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210136, Length=213, Percent_Identity=30.5164319248826, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210134, Length=213, Percent_Identity=30.5164319248826, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32564399, Length=213, Percent_Identity=30.5164319248826, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507425, Length=208, Percent_Identity=26.4423076923077, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324513, Length=362, Percent_Identity=24.585635359116, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=278, Percent_Identity=25.8992805755396, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI22026922, Length=204, Percent_Identity=28.921568627451, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136204, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17136200, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17136202, Length=202, Percent_Identity=28.2178217821782, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 32557; Mature: 32557

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETTISILGAGAWGASLANLAIANGNRVRVWSRRGSETLSAVLQGADIVLSAISMKGVR
CCCCEEEEEECCCHHHHHHHEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
EVASQIQSLTPSPETIFVTATKGLEPETIYTPSQIWQSCFPHHPVVVLSGPNLSKEIDQS
HHHHHHHHCCCCCCEEEEEEECCCCCCEEECHHHHHHHHCCCCCEEEEECCCCHHHHHHH
LPAATVVASRVATAAATVQLAFSSSRFRVYTNPDPVGVELGGTLKNVIAIASGVCDGLHL
CCHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCCEEECHHHHHHHHHHHHHCCCCCC
GTNAKAALVTRGLTEMVRIGNCWGAKTETFYGLSGLGDLLATCNSPLSRNYQVGYQLAGG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCCCCCCCEEEEEECCH
ETLAQILAKLPGTAEGVNTCQVLVQLARQQNIVIPITEQVYRLLQGEVTPQQALDELMLR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHH
DIKPEYN
HCCCCCC
>Mature Secondary Structure
MQETTISILGAGAWGASLANLAIANGNRVRVWSRRGSETLSAVLQGADIVLSAISMKGVR
CCCCEEEEEECCCHHHHHHHEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
EVASQIQSLTPSPETIFVTATKGLEPETIYTPSQIWQSCFPHHPVVVLSGPNLSKEIDQS
HHHHHHHHCCCCCCEEEEEEECCCCCCEEECHHHHHHHHCCCCCEEEEECCCCHHHHHHH
LPAATVVASRVATAAATVQLAFSSSRFRVYTNPDPVGVELGGTLKNVIAIASGVCDGLHL
CCHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCCEEECHHHHHHHHHHHHHCCCCCC
GTNAKAALVTRGLTEMVRIGNCWGAKTETFYGLSGLGDLLATCNSPLSRNYQVGYQLAGG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCCCCCCCEEEEEECCH
ETLAQILAKLPGTAEGVNTCQVLVQLARQQNIVIPITEQVYRLLQGEVTPQQALDELMLR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHH
DIKPEYN
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA